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The map label for this gene is artJ [H]

Identifier: 108797844

GI number: 108797844

Start: 963930

End: 964739

Strand: Reverse

Name: artJ [H]

Synonym: Mmcs_0869

Alternate gene names: 108797844

Gene position: 964739-963930 (Counterclockwise)

Preceding gene: 108797845

Following gene: 108797843

Centisome position: 16.91

GC content: 66.17

Gene sequence:

>810_bases
GTGGGGGCCATCGCGCTCGCGCTGGTCTCCGCGTGTTCGAGCAGCACCCCCGCCGAGAACTCCGGTGCCGAGGCCGATCC
GGCCTCGCGCGAGATCGTCATCGGCACATCCGGCGACTTCCCGCCGGTGTCGTTCCTCGAAGACGGCTCCACCGAGGTGG
TCGGCTTCGAGAACGACCTCGCCAAGGGCGTGACCGACGACCTGGGCTGGACCTACCGATTCGAGCAGATCTCGTTCGAC
GGTCTGCTGCCCGCGCTGCAGTCCGGGCGCATCGACGCGATCCTGTCGGGCATGTACAACACGGAGAAACGCCGGGAGCA
GGTCGATTTCATCGACTACATGCAGATCCCGCTGTCTGTGCTGACGACGGTCGACAACGCCCCGAAGACCCCCGGGCCGG
AGGCGCTGTGCGGGCAGTCGGTGGCCTATCTGACCGCGAGCCCGCCCGAACGTGCGCAGCTCGACGCGTGGTCGCAACAG
TGCACCGACAGCGGTAAACCTCCGCTGCAGCCGACCGGTTTCCCCTCCGTCGCACAAGGTGTCAACGCCGTCGCGACCGG
TCGCGTGTACGCACAGCTCGAGGGTGACATCGTGACCCTCTACATCTCGCGCACCGAATTCGGCGACAAACTCGACGTCG
CGTTCAACGTCGAGGGCGAGAAGAGCGTCGTGGGCATGGCGGTGGCGAAGGACAGCCCGCTCAAACCGGAACTGCAGAAG
GCCATGGAGAGTTACGTCGCGTCCGAGGCGTACTGCCAGTCGGCCCAACAGTGGCAGTTCACGGCCGCCAATCCCATCCG
CCAGTGTTGA

Upstream 100 bases:

>100_bases
CGCTATCTCCTCGACGTCTGACACCGACACCCACGATCAGGAAGTGACCAGCATGATGCGACGCCATCGGATGCCGATCG
TAATGGGAGCCGCGGGAGCA

Downstream 100 bases:

>100_bases
CGGAGTTCTGGTATTACTTCACGCTGCCGGAACTGATCGACGGTGGCCTGCTGGCACTGCGGATCGCGCTGCTGTCGCTG
ATCATCGCCTGGCCGGCGGG

Product: extracellular solute-binding protein

Products: ADP; phosphate; L-histidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MGAIALALVSACSSSTPAENSGAEADPASREIVIGTSGDFPPVSFLEDGSTEVVGFENDLAKGVTDDLGWTYRFEQISFD
GLLPALQSGRIDAILSGMYNTEKRREQVDFIDYMQIPLSVLTTVDNAPKTPGPEALCGQSVAYLTASPPERAQLDAWSQQ
CTDSGKPPLQPTGFPSVAQGVNAVATGRVYAQLEGDIVTLYISRTEFGDKLDVAFNVEGEKSVVGMAVAKDSPLKPELQK
AMESYVASEAYCQSAQQWQFTAANPIRQC

Sequences:

>Translated_269_residues
MGAIALALVSACSSSTPAENSGAEADPASREIVIGTSGDFPPVSFLEDGSTEVVGFENDLAKGVTDDLGWTYRFEQISFD
GLLPALQSGRIDAILSGMYNTEKRREQVDFIDYMQIPLSVLTTVDNAPKTPGPEALCGQSVAYLTASPPERAQLDAWSQQ
CTDSGKPPLQPTGFPSVAQGVNAVATGRVYAQLEGDIVTLYISRTEFGDKLDVAFNVEGEKSVVGMAVAKDSPLKPELQK
AMESYVASEAYCQSAQQWQFTAANPIRQC
>Mature_268_residues
GAIALALVSACSSSTPAENSGAEADPASREIVIGTSGDFPPVSFLEDGSTEVVGFENDLAKGVTDDLGWTYRFEQISFDG
LLPALQSGRIDAILSGMYNTEKRREQVDFIDYMQIPLSVLTTVDNAPKTPGPEALCGQSVAYLTASPPERAQLDAWSQQC
TDSGKPPLQPTGFPSVAQGVNAVATGRVYAQLEGDIVTLYISRTEFGDKLDVAFNVEGEKSVVGMAVAKDSPLKPELQKA
MESYVASEAYCQSAQQWQFTAANPIRQC

Specific function: Probably part of an ABC transporter complex involved in arginine transport. Binds arginine. Interacts with host epithelial cells, suggesting a role in host-cell adhesion during infection [H]

COG id: COG0834

COG function: function code ET; ABC-type amino acid transport/signal transduction systems, periplasmic component/domain

Gene ontology:

Cell location: Secreted. Cell surface [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1788648, Length=129, Percent_Identity=31.0077519379845, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788649, Length=132, Percent_Identity=28.7878787878788, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 3400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 320 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001638 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 28718; Mature: 28587

Theoretical pI: Translated: 4.04; Mature: 4.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAIALALVSACSSSTPAENSGAEADPASREIVIGTSGDFPPVSFLEDGSTEVVGFENDL
CCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHCCCCCEEEEECHHHH
AKGVTDDLGWTYRFEQISFDGLLPALQSGRIDAILSGMYNTEKRREQVDFIDYMQIPLSV
HHCCHHCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTVDNAPKTPGPEALCGQSVAYLTASPPERAQLDAWSQQCTDSGKPPLQPTGFPSVAQG
HHHHCCCCCCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHC
VNAVATGRVYAQLEGDIVTLYISRTEFGDKLDVAFNVEGEKSVVGMAVAKDSPLKPELQK
CCCEECCEEEEEECCCEEEEEEECCCCCCEEEEEEECCCCCCEEEEEEECCCCCCHHHHH
AMESYVASEAYCQSAQQWQFTAANPIRQC
HHHHHHHHHHHHCCHHCEEEECCCCCCCC
>Mature Secondary Structure 
GAIALALVSACSSSTPAENSGAEADPASREIVIGTSGDFPPVSFLEDGSTEVVGFENDL
CHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHCCCCCEEEEECHHHH
AKGVTDDLGWTYRFEQISFDGLLPALQSGRIDAILSGMYNTEKRREQVDFIDYMQIPLSV
HHCCHHCCCCEEEEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTTVDNAPKTPGPEALCGQSVAYLTASPPERAQLDAWSQQCTDSGKPPLQPTGFPSVAQG
HHHHCCCCCCCCCHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHC
VNAVATGRVYAQLEGDIVTLYISRTEFGDKLDVAFNVEGEKSVVGMAVAKDSPLKPELQK
CCCEECCEEEEEECCCEEEEEEECCCCCCEEEEEEECCCCCCEEEEEEECCCCCCHHHHH
AMESYVASEAYCQSAQQWQFTAANPIRQC
HHHHHHHHHHHHCCHHCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9784136 [H]