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The map label for this gene is kasB [H]

Identifier: 108797762

GI number: 108797762

Start: 842996

End: 844246

Strand: Direct

Name: kasB [H]

Synonym: Mmcs_0783

Alternate gene names: 108797762

Gene position: 842996-844246 (Clockwise)

Preceding gene: 108797761

Following gene: 108797763

Centisome position: 14.78

GC content: 70.74

Gene sequence:

>1251_bases
ATGGCCAAGTTGAGAACCGGCAGCGGATTCGGCGATGTGGTGGTGACCGCGGTCGCCTCCACCACGGCGGTGGCACCCGA
CGCCGAGGACACCTGGCAGCAGTTGCTGGCGGGCCACAGCGGTATCCGCGCGCTGGACTCCTGGTTCGTCGACGAACTCG
ACTCGCCGGTGCGCATCGGCGGGCAGCTGCGGGAGAACTCCGACGCCTACCTCAACCGTGTCGAGCTGCGCCGGCTGGCG
TACATGCAGAAGATGTCGACGGTGCTGGGCCGCCGGTTGTGGGAGGCGGCGGGCACGCCCGACATCGACCCGCGGCGGCT
GATGGTGTCGATCGGACTCGCGCTCGGCTCCACCGAGGAGATCCCGGCGCAGTACGACGACTGGCGGCAGAAGGGTCTGC
GCGCGGTGTCGCCGCTGGCGGTGCAGATGTACATGCCCAACGCCCCGGCCGCCGCGGTCGGACTGGACCGGCAGGCCAAG
GGCGGCATCATCTCTCCGGTGATGGCCGACGCGTCGGGGGCGGCCGCCATCGCCCAGGCGTGGCGCCAGATCGTGCTCGG
CGAGGTCGAGATGGCGATCTGCGGCGGGGTGGAGACCAAGATCGAGGCGGTCCCGGTGGGCGCGTTCACGCGGTTGGGTC
TGTTGTCCACCAACAACGACGATCCGGCCGGTGCGTGCCGCCCATTCGACAAGGACCGCGACGGCATGGTGCTCGGTGAG
GGCGGCGCGCTGCTGCTCATCGAGACCGAGGAGAACGCCAAGGCGCGCGGCGCGACGATCCTCGGCCGGATCATGGGCGC
GGCGATGACCTCGGACGGCTACGACATCGTCGAACCGGATCCGAGCGGGGTGCCCGCCGGCGACGCGATCCGGCACGCGG
TCGATCTGGCTGGCCTCGAGCCGTCCGACGTCGACCTGGTCAATGCCCACGCCACCGGTACGGCGTTCGGCGACGTGGCC
GAGGGATGCGCCATCCGGCACGCGCTGGGTGCGCACCGTCCGGCGGTGTACGCACCCAAAGCGGCGCTGGGGCATTCGCT
CGGCGCGGCCGGCGCCGTCGAGGCGGTGTTGACGGTCCAGGCGTTGCGCGACGGGGTGGTGCCGCCGACGCTCAACGTGC
AGCATCTCGACGCCGACATCGACCTCGACGTCGTCACAGGTGAGCCCCGGCGCGGCGACTTCCGTTATGCGGTCAGCAAC
TCGTTCGGCCTCGGCGGGCACAACATCGTGCTGGTGTTCGGCGCGTACTGA

Upstream 100 bases:

>100_bases
TGCGCTGATTCCCGTGCCGGGGGCCGAAAGCCGCGGCGGCGCAGCGTAACCTCTGGGGGACACTCAACGTCGTCGAGGAG
CAGTGGAGGATTCCGCAGGC

Downstream 100 bases:

>100_bases
GCCGCGGCGTCTGATTCACACGTCTCATCCGAAGCGCCCGCCATAAGCGGACTTTCGCCTTAACGTCGGGCCGGTGTCGT
TGATCTCCACCGCCCTGCTT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: Beta-ketoacyl-ACP synthase 2; KAS 2 [H]

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MAKLRTGSGFGDVVVTAVASTTAVAPDAEDTWQQLLAGHSGIRALDSWFVDELDSPVRIGGQLRENSDAYLNRVELRRLA
YMQKMSTVLGRRLWEAAGTPDIDPRRLMVSIGLALGSTEEIPAQYDDWRQKGLRAVSPLAVQMYMPNAPAAAVGLDRQAK
GGIISPVMADASGAAAIAQAWRQIVLGEVEMAICGGVETKIEAVPVGAFTRLGLLSTNNDDPAGACRPFDKDRDGMVLGE
GGALLLIETEENAKARGATILGRIMGAAMTSDGYDIVEPDPSGVPAGDAIRHAVDLAGLEPSDVDLVNAHATGTAFGDVA
EGCAIRHALGAHRPAVYAPKAALGHSLGAAGAVEAVLTVQALRDGVVPPTLNVQHLDADIDLDVVTGEPRRGDFRYAVSN
SFGLGGHNIVLVFGAY

Sequences:

>Translated_416_residues
MAKLRTGSGFGDVVVTAVASTTAVAPDAEDTWQQLLAGHSGIRALDSWFVDELDSPVRIGGQLRENSDAYLNRVELRRLA
YMQKMSTVLGRRLWEAAGTPDIDPRRLMVSIGLALGSTEEIPAQYDDWRQKGLRAVSPLAVQMYMPNAPAAAVGLDRQAK
GGIISPVMADASGAAAIAQAWRQIVLGEVEMAICGGVETKIEAVPVGAFTRLGLLSTNNDDPAGACRPFDKDRDGMVLGE
GGALLLIETEENAKARGATILGRIMGAAMTSDGYDIVEPDPSGVPAGDAIRHAVDLAGLEPSDVDLVNAHATGTAFGDVA
EGCAIRHALGAHRPAVYAPKAALGHSLGAAGAVEAVLTVQALRDGVVPPTLNVQHLDADIDLDVVTGEPRRGDFRYAVSN
SFGLGGHNIVLVFGAY
>Mature_415_residues
AKLRTGSGFGDVVVTAVASTTAVAPDAEDTWQQLLAGHSGIRALDSWFVDELDSPVRIGGQLRENSDAYLNRVELRRLAY
MQKMSTVLGRRLWEAAGTPDIDPRRLMVSIGLALGSTEEIPAQYDDWRQKGLRAVSPLAVQMYMPNAPAAAVGLDRQAKG
GIISPVMADASGAAAIAQAWRQIVLGEVEMAICGGVETKIEAVPVGAFTRLGLLSTNNDDPAGACRPFDKDRDGMVLGEG
GALLLIETEENAKARGATILGRIMGAAMTSDGYDIVEPDPSGVPAGDAIRHAVDLAGLEPSDVDLVNAHATGTAFGDVAE
GCAIRHALGAHRPAVYAPKAALGHSLGAAGAVEAVLTVQALRDGVVPPTLNVQHLDADIDLDVVTGEPRRGDFRYAVSNS
FGLGGHNIVLVFGAY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=31.7307692307692, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI223972627, Length=146, Percent_Identity=40.4109589041096, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI41872631, Length=270, Percent_Identity=30, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1787337, Length=407, Percent_Identity=36.1179361179361, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1788663, Length=413, Percent_Identity=32.9297820823245, Blast_Score=163, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI71983541, Length=327, Percent_Identity=34.5565749235474, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI71983535, Length=262, Percent_Identity=36.6412213740458, Blast_Score=163, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17550940, Length=303, Percent_Identity=26.4026402640264, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI212642053, Length=423, Percent_Identity=25.7683215130024, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6320904, Length=445, Percent_Identity=30.3370786516854, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24644341, Length=436, Percent_Identity=35.7798165137615, Blast_Score=228, Evalue=7e-60,
Organism=Drosophila melanogaster, GI221330659, Length=261, Percent_Identity=29.1187739463602, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI19920632, Length=259, Percent_Identity=28.957528957529, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24581345, Length=332, Percent_Identity=24.6987951807229, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 43502; Mature: 43371

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLRTGSGFGDVVVTAVASTTAVAPDAEDTWQQLLAGHSGIRALDSWFVDELDSPVRIG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEC
GQLRENSDAYLNRVELRRLAYMQKMSTVLGRRLWEAAGTPDIDPRRLMVSIGLALGSTEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEHHHCCCCCC
IPAQYDDWRQKGLRAVSPLAVQMYMPNAPAAAVGLDRQAKGGIISPVMADASGAAAIAQA
CCCCHHHHHHHCCHHCCCEEEEEECCCCCHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHH
WRQIVLGEVEMAICGGVETKIEAVPVGAFTRLGLLSTNNDDPAGACRPFDKDRDGMVLGE
HHHHHHHHHHEEEECCCCCEEEEECCCHHHHEEEEECCCCCCCCCCCCCCCCCCCEEEEC
GGALLLIETEENAKARGATILGRIMGAAMTSDGYDIVEPDPSGVPAGDAIRHAVDLAGLE
CCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHCCCC
PSDVDLVNAHATGTAFGDVAEGCAIRHALGAHRPAVYAPKAALGHSLGAAGAVEAVLTVQ
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEECCHHHHCCCCCCHHHHHHHHHHH
ALRDGVVPPTLNVQHLDADIDLDVVTGEPRRGDFRYAVSNSFGLGGHNIVLVFGAY
HHHCCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
AKLRTGSGFGDVVVTAVASTTAVAPDAEDTWQQLLAGHSGIRALDSWFVDELDSPVRIG
CCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEC
GQLRENSDAYLNRVELRRLAYMQKMSTVLGRRLWEAAGTPDIDPRRLMVSIGLALGSTEE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHEEEEEHHHCCCCCC
IPAQYDDWRQKGLRAVSPLAVQMYMPNAPAAAVGLDRQAKGGIISPVMADASGAAAIAQA
CCCCHHHHHHHCCHHCCCEEEEEECCCCCHHHHCCCCCCCCCCCCHHHCCCCCHHHHHHH
WRQIVLGEVEMAICGGVETKIEAVPVGAFTRLGLLSTNNDDPAGACRPFDKDRDGMVLGE
HHHHHHHHHHEEEECCCCCEEEEECCCHHHHEEEEECCCCCCCCCCCCCCCCCCCEEEEC
GGALLLIETEENAKARGATILGRIMGAAMTSDGYDIVEPDPSGVPAGDAIRHAVDLAGLE
CCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHHHHCCCC
PSDVDLVNAHATGTAFGDVAEGCAIRHALGAHRPAVYAPKAALGHSLGAAGAVEAVLTVQ
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEECCHHHHCCCCCCHHHHHHHHHHH
ALRDGVVPPTLNVQHLDADIDLDVVTGEPRRGDFRYAVSNSFGLGGHNIVLVFGAY
HHHCCCCCCCCCCEEECCCCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]