| Definition | Mycobacterium sp. MCS chromosome, complete genome. |
|---|---|
| Accession | NC_008146 |
| Length | 5,705,448 |
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The map label for this gene is hflB [C]
Identifier: 108797572
GI number: 108797572
Start: 651149
End: 653374
Strand: Reverse
Name: hflB [C]
Synonym: Mmcs_0592
Alternate gene names: 108797572
Gene position: 653374-651149 (Counterclockwise)
Preceding gene: 108797573
Following gene: 108797571
Centisome position: 11.45
GC content: 72.55
Gene sequence:
>2226_bases ATGACCGAGGCCGGACTGTCCGAGCGCGAACCGAATCTGAGCCACCTGCGGCTCACGGCGCGGTTGAACACCGCCGCCCT CGACTCCCGGCGCGGGGTGGTCCGGCTGCATCCGGAGGTGATCGCCGCGCTCGGGATCCGGGAGTGGGATGCGGTGTCGC TCACCGGCGCACGGACGACGGCCGCGGTGGTCGGCATCGCCCCGCCGGGCACGCCGACGGGCACCGCCCTGCTCGACGAC GTGACGCTGTCCAACGCCGGGCTGCCCGAGAACAGCAGCGTCATCGTGGCGCCGGTGACGGTCTACGGCGCACGATCGGT GACCGTGTCGGGGTCCCGGCTGGCCACCAACTCGATCTCCCCGGCCACTCTGCGCCAGGCGCTGCTGGGCAAGGTGATGA CGGTCGGCGACACCGTCTCGCTGCTCCCCCGCGATCTGGGCCCCGGCACGTCGACGTCGTCGGCGACCACCGCGCTCGCG TCGTCGGTGGGCATCACCTGGACCTCGGAACTGCTGACGGTCACCAGCGTCGACCCTCCGGGCACCGTGAGCATCCAGCC GAATTCGTCGGTCACCTGGGGTGACGGACCCGCGCCGAAGGCCGCGTCCGCCGGCCCGACCGACGGCGCGGCGGTCGGCG AGGCCACCGTCACCACACCGTCGGTGGACCGACCGGCGGTGTCCTTCGACGATCTCAAGGGCAGCCACGCGCAGGCCGGC CGGCTCACGGAATGGCTGAAGCTCTCCCTCGACGAGCCGTCGTTGCTCGAGACGCTCGGCGCCACAGCGCATCTCGGCGT GCTGGTATCGGGTCCGGCCGGGGTGGGCAAGGCCACGCTGGTGCGGACGGTGTGCGCCCAGCGACGGCTCGTCGAATTGG ACGGTCCGGAGGTCGGCGCGCTGCATGCCGAGGACCGGCTCAACCGGGTGTCGTCGGCGGTGTCGACGGTCCGCGACGGC GGCGGCGTACTGCTGATCTCCGACATCGACGCACTGCTGCCCGCGACGCCGGAACCGGTGGGCACGCTGATCCTCACCGA ACTGCGCACCGCCGTCGCGACACCCGGTGTCGCGTTCGTGGCGACCTCGGCCAGGCCGGACGGCGTCGACGCCCGCCTGC GCGACCCCGACCTCTGCGACCGTGAGCTCGGGCTGAGCCTGCCCGACGCGGCCACTCGTAAGGAGCTGCTCGAGGTGCTG CTGCGCAGCGTCCCGGCGCAGGAACTGCACCTCGACGAGATCGCCGGACGCACACCGGGTTTCGTGATCGCCGACCTGTG CGCGCTGGTGCGTGAGGCGGCGCTGCGGGCGGCGGCGCGGGCCAGTGCCGACGGGGCGCCGCCGCAACTCACCCAGGCGG ATCTCACCGGTGCGCTCACCGTGATCCGTCCGCTGTCGAGGTCGGCCACCGAAGAGGTGTCGGTCGGGTCGGTCACCCTC GCCGACGTCGGCGACATGACCGAGACCAAGCAGGCGCTGACCGAGGCGGTGTTGTGGCCGCTGCAGCATCCGGACACCTT CGAACGCCTCGGCATCGAACCGCCGCGCGGGGTGCTGCTCTACGGACCGCCGGGCTGCGGGAAGACCTTCGTGGTGCGCG CCCTCGCCAGTTCGGGGCGGCTGTCGGTGCACGCGGTCAAGGGCGCCGAGCTCATGGACAAATGGGTCGGCGCCTCGGAG AAGGCGGTGCGCGAACTGTTCCGCAGGGCGCGCGACTCCGCCCCGTCGCTGGTGTTCCTCGACGAGATCGACGCGCTCGC GCCGCGGCGCGGGCAGAGCTTCGACTCCGGGGTGACCGACCGGGTCGTGGCGTCGCTGCTGACCGAACTCGACGGCATCG AACCGATGTGCAACGTCGTCGTGCTGGGCGCCACGAACCGGCCCGATCTGATCGACCCCGCGCTGCTGCGGCCCGGGCGG TTGGAGCGGCTGGTGTTCGTCGAACCGCCCGACGCCGAGGCGCGCCGCGAGATCCTGCGCACCGCAGGCAAATCCGTACC GCTCGCCGACGACGTCGACCTCGACACGCTGGCCGCCGGTCTCGACGGGTACAGCGCTGCGGACTGCGTCGCGCTGCTGC GGGAGGCGGCGATGACGGCGATGCGACGATCGATCGACGCCGCCGACGTCACTGCCGCCGACGTGGAGGCCGCCCGCCAG ACGGTGCGCCCGTCGCTGGACCCGCTGCAGGTCGACACGCTGCGGGCGTTCGCGGAGAACCGCTGA
Upstream 100 bases:
>100_bases CGCCGCGCGATCCGCCGCGCCTCCCGTCGCGAGATCCGGCGCACCCAACCGCACCGCCGTTCGGTGGCCCGGCTGGGTCT GCGCAAACCGGGCAGGTGAC
Downstream 100 bases:
>100_bases ACACCGCGGGCATAAATCTTGACAGTGCCTAGTTGTGGTGGGACAGTCGAACCATCGCAACTAGCCACTGTCTAGATGAC TTCGGGAGGCATCATGACCG
Product: vesicle-fusing ATPase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 741; Mature: 740
Protein sequence:
>741_residues MTEAGLSEREPNLSHLRLTARLNTAALDSRRGVVRLHPEVIAALGIREWDAVSLTGARTTAAVVGIAPPGTPTGTALLDD VTLSNAGLPENSSVIVAPVTVYGARSVTVSGSRLATNSISPATLRQALLGKVMTVGDTVSLLPRDLGPGTSTSSATTALA SSVGITWTSELLTVTSVDPPGTVSIQPNSSVTWGDGPAPKAASAGPTDGAAVGEATVTTPSVDRPAVSFDDLKGSHAQAG RLTEWLKLSLDEPSLLETLGATAHLGVLVSGPAGVGKATLVRTVCAQRRLVELDGPEVGALHAEDRLNRVSSAVSTVRDG GGVLLISDIDALLPATPEPVGTLILTELRTAVATPGVAFVATSARPDGVDARLRDPDLCDRELGLSLPDAATRKELLEVL LRSVPAQELHLDEIAGRTPGFVIADLCALVREAALRAAARASADGAPPQLTQADLTGALTVIRPLSRSATEEVSVGSVTL ADVGDMTETKQALTEAVLWPLQHPDTFERLGIEPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMDKWVGASE KAVRELFRRARDSAPSLVFLDEIDALAPRRGQSFDSGVTDRVVASLLTELDGIEPMCNVVVLGATNRPDLIDPALLRPGR LERLVFVEPPDAEARREILRTAGKSVPLADDVDLDTLAAGLDGYSAADCVALLREAAMTAMRRSIDAADVTAADVEAARQ TVRPSLDPLQVDTLRAFAENR
Sequences:
>Translated_741_residues MTEAGLSEREPNLSHLRLTARLNTAALDSRRGVVRLHPEVIAALGIREWDAVSLTGARTTAAVVGIAPPGTPTGTALLDD VTLSNAGLPENSSVIVAPVTVYGARSVTVSGSRLATNSISPATLRQALLGKVMTVGDTVSLLPRDLGPGTSTSSATTALA SSVGITWTSELLTVTSVDPPGTVSIQPNSSVTWGDGPAPKAASAGPTDGAAVGEATVTTPSVDRPAVSFDDLKGSHAQAG RLTEWLKLSLDEPSLLETLGATAHLGVLVSGPAGVGKATLVRTVCAQRRLVELDGPEVGALHAEDRLNRVSSAVSTVRDG GGVLLISDIDALLPATPEPVGTLILTELRTAVATPGVAFVATSARPDGVDARLRDPDLCDRELGLSLPDAATRKELLEVL LRSVPAQELHLDEIAGRTPGFVIADLCALVREAALRAAARASADGAPPQLTQADLTGALTVIRPLSRSATEEVSVGSVTL ADVGDMTETKQALTEAVLWPLQHPDTFERLGIEPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMDKWVGASE KAVRELFRRARDSAPSLVFLDEIDALAPRRGQSFDSGVTDRVVASLLTELDGIEPMCNVVVLGATNRPDLIDPALLRPGR LERLVFVEPPDAEARREILRTAGKSVPLADDVDLDTLAAGLDGYSAADCVALLREAAMTAMRRSIDAADVTAADVEAARQ TVRPSLDPLQVDTLRAFAENR >Mature_740_residues TEAGLSEREPNLSHLRLTARLNTAALDSRRGVVRLHPEVIAALGIREWDAVSLTGARTTAAVVGIAPPGTPTGTALLDDV TLSNAGLPENSSVIVAPVTVYGARSVTVSGSRLATNSISPATLRQALLGKVMTVGDTVSLLPRDLGPGTSTSSATTALAS SVGITWTSELLTVTSVDPPGTVSIQPNSSVTWGDGPAPKAASAGPTDGAAVGEATVTTPSVDRPAVSFDDLKGSHAQAGR LTEWLKLSLDEPSLLETLGATAHLGVLVSGPAGVGKATLVRTVCAQRRLVELDGPEVGALHAEDRLNRVSSAVSTVRDGG GVLLISDIDALLPATPEPVGTLILTELRTAVATPGVAFVATSARPDGVDARLRDPDLCDRELGLSLPDAATRKELLEVLL RSVPAQELHLDEIAGRTPGFVIADLCALVREAALRAAARASADGAPPQLTQADLTGALTVIRPLSRSATEEVSVGSVTLA DVGDMTETKQALTEAVLWPLQHPDTFERLGIEPPRGVLLYGPPGCGKTFVVRALASSGRLSVHAVKGAELMDKWVGASEK AVRELFRRARDSAPSLVFLDEIDALAPRRGQSFDSGVTDRVVASLLTELDGIEPMCNVVVLGATNRPDLIDPALLRPGRL ERLVFVEPPDAEARREILRTAGKSVPLADDVDLDTLAAGLDGYSAADCVALLREAAMTAMRRSIDAADVTAADVEAARQT VRPSLDPLQVDTLRAFAENR
Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving
COG id: COG0464
COG function: function code O; ATPases of the AAA+ class
Gene ontology:
Cell location: Integral Membrane Protein. Inner Membrane [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]
Homologues:
Organism=Homo sapiens, GI157671927, Length=547, Percent_Identity=39.1224862888483, Blast_Score=347, Evalue=2e-95, Organism=Homo sapiens, GI6005942, Length=499, Percent_Identity=35.0701402805611, Blast_Score=293, Evalue=3e-79, Organism=Homo sapiens, GI45643125, Length=550, Percent_Identity=35.4545454545455, Blast_Score=281, Evalue=2e-75, Organism=Homo sapiens, GI45643123, Length=550, Percent_Identity=35.4545454545455, Blast_Score=281, Evalue=2e-75, Organism=Homo sapiens, GI229577436, Length=508, Percent_Identity=36.8110236220472, Blast_Score=278, Evalue=9e-75, Organism=Homo sapiens, GI4505725, Length=470, Percent_Identity=34.8936170212766, Blast_Score=235, Evalue=1e-61, Organism=Homo sapiens, GI194018488, Length=474, Percent_Identity=34.3881856540084, Blast_Score=200, Evalue=4e-51, Organism=Homo sapiens, GI24497618, Length=270, Percent_Identity=40.7407407407407, Blast_Score=196, Evalue=9e-50, Organism=Homo sapiens, GI5729991, Length=250, Percent_Identity=41.2, Blast_Score=194, Evalue=2e-49, Organism=Homo sapiens, GI24430155, Length=250, Percent_Identity=41.2, Blast_Score=194, Evalue=2e-49, Organism=Homo sapiens, GI89064750, Length=250, Percent_Identity=41.2, Blast_Score=194, Evalue=3e-49, Organism=Homo sapiens, GI24430151, Length=246, Percent_Identity=41.0569105691057, Blast_Score=192, Evalue=1e-48, Organism=Homo sapiens, GI21361144, Length=238, Percent_Identity=39.4957983193277, Blast_Score=189, Evalue=1e-47, Organism=Homo sapiens, GI153792536, Length=233, Percent_Identity=43.7768240343348, Blast_Score=188, Evalue=2e-47, Organism=Homo sapiens, GI195539395, Length=258, Percent_Identity=38.3720930232558, Blast_Score=187, Evalue=4e-47, Organism=Homo sapiens, GI4506209, Length=230, Percent_Identity=43.0434782608696, Blast_Score=181, Evalue=2e-45, Organism=Homo sapiens, GI24497435, Length=243, Percent_Identity=40.7407407407407, Blast_Score=181, Evalue=2e-45, Organism=Homo sapiens, GI5901990, Length=291, Percent_Identity=37.4570446735395, Blast_Score=177, Evalue=3e-44, Organism=Homo sapiens, GI156564401, Length=259, Percent_Identity=39.7683397683398, Blast_Score=164, Evalue=2e-40, Organism=Homo sapiens, GI300192933, Length=238, Percent_Identity=37.8151260504202, Blast_Score=164, Evalue=3e-40, Organism=Homo sapiens, GI21327685, Length=256, Percent_Identity=35.15625, Blast_Score=164, Evalue=4e-40, Organism=Homo sapiens, GI7657689, Length=256, Percent_Identity=35.15625, Blast_Score=164, Evalue=4e-40, Organism=Homo sapiens, GI14149767, Length=238, Percent_Identity=40.3361344537815, Blast_Score=162, Evalue=8e-40, Organism=Homo sapiens, GI62177112, Length=238, Percent_Identity=40.3361344537815, Blast_Score=162, Evalue=8e-40, Organism=Homo sapiens, GI310125280, Length=231, Percent_Identity=41.1255411255411, Blast_Score=162, Evalue=1e-39, Organism=Homo sapiens, GI310125282, Length=233, Percent_Identity=40.7725321888412, Blast_Score=162, Evalue=1e-39, Organism=Homo sapiens, GI4507173, Length=230, Percent_Identity=38.695652173913, Blast_Score=154, Evalue=2e-37, Organism=Homo sapiens, GI31742536, Length=265, Percent_Identity=34.7169811320755, Blast_Score=151, Evalue=3e-36, Organism=Homo sapiens, GI112789543, Length=265, Percent_Identity=34.7169811320755, Blast_Score=151, Evalue=3e-36, Organism=Homo sapiens, GI7019569, Length=267, Percent_Identity=32.5842696629214, Blast_Score=142, Evalue=8e-34, Organism=Homo sapiens, GI17865802, Length=257, Percent_Identity=33.4630350194552, Blast_Score=142, Evalue=1e-33, Organism=Homo sapiens, GI31377644, Length=275, Percent_Identity=31.2727272727273, Blast_Score=139, Evalue=1e-32, Organism=Homo sapiens, GI226371754, Length=244, Percent_Identity=34.0163934426229, Blast_Score=138, Evalue=2e-32, Organism=Homo sapiens, GI11875211, Length=275, Percent_Identity=33.4545454545455, Blast_Score=133, Evalue=6e-31, Organism=Homo sapiens, GI40806170, Length=275, Percent_Identity=33.4545454545455, Blast_Score=133, Evalue=7e-31, Organism=Homo sapiens, GI64084766, Length=269, Percent_Identity=28.996282527881, Blast_Score=104, Evalue=3e-22, Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=37.6811594202899, Blast_Score=94, Evalue=3e-19, Organism=Homo sapiens, GI116292174, Length=258, Percent_Identity=29.4573643410853, Blast_Score=86, Evalue=2e-16, Organism=Escherichia coli, GI1789568, Length=256, Percent_Identity=38.28125, Blast_Score=185, Evalue=1e-47, Organism=Caenorhabditis elegans, GI17532375, Length=504, Percent_Identity=33.9285714285714, Blast_Score=298, Evalue=6e-81, Organism=Caenorhabditis elegans, GI17531535, Length=506, Percent_Identity=33.9920948616601, Blast_Score=290, Evalue=1e-78, Organism=Caenorhabditis elegans, GI17508053, Length=312, Percent_Identity=48.0769230769231, Blast_Score=271, Evalue=9e-73, Organism=Caenorhabditis elegans, GI17537217, Length=590, Percent_Identity=31.5254237288136, Blast_Score=255, Evalue=5e-68, Organism=Caenorhabditis elegans, GI25153574, Length=393, Percent_Identity=34.3511450381679, Blast_Score=216, Evalue=3e-56, Organism=Caenorhabditis elegans, GI17562804, Length=486, Percent_Identity=29.6296296296296, Blast_Score=205, Evalue=6e-53, Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=45.3333333333333, Blast_Score=201, Evalue=1e-51, Organism=Caenorhabditis elegans, GI71987364, Length=258, Percent_Identity=40.6976744186046, Blast_Score=191, Evalue=8e-49, Organism=Caenorhabditis elegans, GI71987372, Length=258, Percent_Identity=40.6976744186046, Blast_Score=191, Evalue=9e-49, Organism=Caenorhabditis elegans, GI17554784, Length=323, Percent_Identity=36.8421052631579, Blast_Score=191, Evalue=1e-48, Organism=Caenorhabditis elegans, GI17563250, Length=246, Percent_Identity=39.8373983739837, Blast_Score=184, Evalue=2e-46, Organism=Caenorhabditis elegans, GI17508701, Length=238, Percent_Identity=38.655462184874, Blast_Score=182, Evalue=5e-46, Organism=Caenorhabditis elegans, GI17554786, Length=243, Percent_Identity=39.917695473251, Blast_Score=179, Evalue=6e-45, Organism=Caenorhabditis elegans, GI17563248, Length=229, Percent_Identity=44.1048034934498, Blast_Score=178, Evalue=1e-44, Organism=Caenorhabditis elegans, GI25144281, Length=243, Percent_Identity=39.917695473251, Blast_Score=177, Evalue=1e-44, Organism=Caenorhabditis elegans, GI25144278, Length=243, Percent_Identity=39.917695473251, Blast_Score=177, Evalue=1e-44, Organism=Caenorhabditis elegans, GI193206116, Length=237, Percent_Identity=42.6160337552743, Blast_Score=177, Evalue=2e-44, Organism=Caenorhabditis elegans, GI193206114, Length=237, Percent_Identity=42.6160337552743, Blast_Score=177, Evalue=3e-44, Organism=Caenorhabditis elegans, GI133931034, Length=237, Percent_Identity=42.6160337552743, Blast_Score=177, Evalue=3e-44, Organism=Caenorhabditis elegans, GI17508421, Length=272, Percent_Identity=38.9705882352941, Blast_Score=167, Evalue=3e-41, Organism=Caenorhabditis elegans, GI32563584, Length=275, Percent_Identity=38.5454545454545, Blast_Score=165, Evalue=8e-41, Organism=Caenorhabditis elegans, GI25146157, Length=277, Percent_Identity=35.0180505415162, Blast_Score=160, Evalue=3e-39, Organism=Caenorhabditis elegans, GI17505546, Length=226, Percent_Identity=36.7256637168142, Blast_Score=159, Evalue=4e-39, Organism=Caenorhabditis elegans, GI86561515, Length=256, Percent_Identity=34.375, Blast_Score=154, Evalue=2e-37, Organism=Caenorhabditis elegans, GI133901662, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=9e-35, Organism=Caenorhabditis elegans, GI133901658, Length=237, Percent_Identity=37.9746835443038, Blast_Score=144, Evalue=1e-34, Organism=Caenorhabditis elegans, GI17554264, Length=237, Percent_Identity=35.4430379746835, Blast_Score=144, Evalue=2e-34, Organism=Caenorhabditis elegans, GI17560432, Length=283, Percent_Identity=36.7491166077738, Blast_Score=144, Evalue=2e-34, Organism=Caenorhabditis elegans, GI115534323, Length=272, Percent_Identity=33.4558823529412, Blast_Score=137, Evalue=2e-32, Organism=Caenorhabditis elegans, GI71994521, Length=234, Percent_Identity=36.7521367521368, Blast_Score=129, Evalue=4e-30, Organism=Caenorhabditis elegans, GI17541224, Length=218, Percent_Identity=33.0275229357798, Blast_Score=119, Evalue=4e-27, Organism=Caenorhabditis elegans, GI17541226, Length=218, Percent_Identity=33.0275229357798, Blast_Score=119, Evalue=4e-27, Organism=Saccharomyces cerevisiae, GI6323429, Length=536, Percent_Identity=35.0746268656716, Blast_Score=301, Evalue=2e-82, Organism=Saccharomyces cerevisiae, GI6320077, Length=551, Percent_Identity=35.02722323049, Blast_Score=299, Evalue=1e-81, Organism=Saccharomyces cerevisiae, GI6322994, Length=567, Percent_Identity=30.5114638447972, Blast_Score=251, Evalue=2e-67, Organism=Saccharomyces cerevisiae, GI6324000, Length=498, Percent_Identity=31.5261044176707, Blast_Score=202, Evalue=1e-52, Organism=Saccharomyces cerevisiae, GI6322651, Length=354, Percent_Identity=33.3333333333333, Blast_Score=198, Evalue=2e-51, Organism=Saccharomyces cerevisiae, GI6320602, Length=230, Percent_Identity=44.3478260869565, Blast_Score=195, Evalue=2e-50, Organism=Saccharomyces cerevisiae, GI6321390, Length=239, Percent_Identity=42.2594142259414, Blast_Score=190, Evalue=7e-49, Organism=Saccharomyces cerevisiae, GI6321709, Length=236, Percent_Identity=41.5254237288136, Blast_Score=184, Evalue=4e-47, Organism=Saccharomyces cerevisiae, GI6320197, Length=246, Percent_Identity=37.8048780487805, Blast_Score=183, Evalue=8e-47, Organism=Saccharomyces cerevisiae, GI6324833, Length=258, Percent_Identity=36.4341085271318, Blast_Score=174, Evalue=5e-44, Organism=Saccharomyces cerevisiae, GI6322704, Length=230, Percent_Identity=40.8695652173913, Blast_Score=171, Evalue=5e-43, Organism=Saccharomyces cerevisiae, GI6323736, Length=258, Percent_Identity=37.984496124031, Blast_Score=169, Evalue=2e-42, Organism=Saccharomyces cerevisiae, GI6325281, Length=251, Percent_Identity=36.2549800796813, Blast_Score=162, Evalue=2e-40, Organism=Saccharomyces cerevisiae, GI6324691, Length=226, Percent_Identity=37.1681415929204, Blast_Score=160, Evalue=6e-40, Organism=Saccharomyces cerevisiae, GI6320854, Length=239, Percent_Identity=36.8200836820084, Blast_Score=150, Evalue=5e-37, Organism=Saccharomyces cerevisiae, GI6319554, Length=245, Percent_Identity=34.6938775510204, Blast_Score=150, Evalue=6e-37, Organism=Saccharomyces cerevisiae, GI6325431, Length=250, Percent_Identity=35.6, Blast_Score=150, Evalue=7e-37, Organism=Saccharomyces cerevisiae, GI6321465, Length=257, Percent_Identity=35.0194552529183, Blast_Score=146, Evalue=2e-35, Organism=Saccharomyces cerevisiae, GI6325183, Length=263, Percent_Identity=33.4600760456274, Blast_Score=136, Evalue=1e-32, Organism=Saccharomyces cerevisiae, GI6320887, Length=268, Percent_Identity=30.9701492537313, Blast_Score=126, Evalue=1e-29, Organism=Saccharomyces cerevisiae, GI6320583, Length=161, Percent_Identity=29.8136645962733, Blast_Score=75, Evalue=6e-14, Organism=Drosophila melanogaster, GI19921202, Length=492, Percent_Identity=38.0081300813008, Blast_Score=308, Evalue=1e-83, Organism=Drosophila melanogaster, GI17137560, Length=510, Percent_Identity=35.0980392156863, Blast_Score=301, Evalue=2e-81, Organism=Drosophila melanogaster, GI161076488, Length=510, Percent_Identity=35.0980392156863, Blast_Score=300, Evalue=2e-81, Organism=Drosophila melanogaster, GI161076486, Length=510, Percent_Identity=35.0980392156863, Blast_Score=300, Evalue=2e-81, Organism=Drosophila melanogaster, GI281365776, Length=293, Percent_Identity=44.0273037542662, Blast_Score=239, Evalue=6e-63, Organism=Drosophila melanogaster, GI24660075, Length=293, Percent_Identity=44.0273037542662, Blast_Score=239, Evalue=6e-63, Organism=Drosophila melanogaster, GI45552965, Length=293, Percent_Identity=44.0273037542662, Blast_Score=239, Evalue=6e-63, Organism=Drosophila melanogaster, GI24656825, Length=533, Percent_Identity=31.5196998123827, Blast_Score=220, Evalue=2e-57, Organism=Drosophila melanogaster, GI24656820, Length=433, Percent_Identity=33.9491916859122, Blast_Score=216, Evalue=6e-56, Organism=Drosophila melanogaster, GI21355121, Length=503, Percent_Identity=31.013916500994, Blast_Score=202, Evalue=6e-52, Organism=Drosophila melanogaster, GI18860063, Length=305, Percent_Identity=37.7049180327869, Blast_Score=198, Evalue=1e-50, Organism=Drosophila melanogaster, GI281361487, Length=249, Percent_Identity=40.1606425702811, Blast_Score=192, Evalue=5e-49, Organism=Drosophila melanogaster, GI24652279, Length=198, Percent_Identity=44.9494949494949, Blast_Score=190, Evalue=4e-48, Organism=Drosophila melanogaster, GI24649446, Length=246, Percent_Identity=40.650406504065, Blast_Score=188, Evalue=1e-47, Organism=Drosophila melanogaster, GI281363136, Length=306, Percent_Identity=38.8888888888889, Blast_Score=187, Evalue=2e-47, Organism=Drosophila melanogaster, GI78707192, Length=306, Percent_Identity=38.8888888888889, Blast_Score=187, Evalue=2e-47, Organism=Drosophila melanogaster, GI17738151, Length=238, Percent_Identity=39.0756302521008, Blast_Score=186, Evalue=7e-47, Organism=Drosophila melanogaster, GI19920408, Length=242, Percent_Identity=40.495867768595, Blast_Score=185, Evalue=8e-47, Organism=Drosophila melanogaster, GI24651451, Length=244, Percent_Identity=40.1639344262295, Blast_Score=182, Evalue=6e-46, Organism=Drosophila melanogaster, GI17137738, Length=230, Percent_Identity=43.4782608695652, Blast_Score=182, Evalue=8e-46, Organism=Drosophila melanogaster, GI24640100, Length=258, Percent_Identity=38.3720930232558, Blast_Score=179, Evalue=8e-45, Organism=Drosophila melanogaster, GI24663015, Length=254, Percent_Identity=38.1889763779528, Blast_Score=176, Evalue=7e-44, Organism=Drosophila melanogaster, GI24658770, Length=247, Percent_Identity=40.4858299595142, Blast_Score=174, Evalue=2e-43, Organism=Drosophila melanogaster, GI24644145, Length=234, Percent_Identity=42.3076923076923, Blast_Score=165, Evalue=8e-41, Organism=Drosophila melanogaster, GI28573010, Length=231, Percent_Identity=39.3939393939394, Blast_Score=154, Evalue=2e-37, Organism=Drosophila melanogaster, GI24639391, Length=249, Percent_Identity=35.3413654618474, Blast_Score=152, Evalue=6e-37, Organism=Drosophila melanogaster, GI17864540, Length=232, Percent_Identity=39.2241379310345, Blast_Score=152, Evalue=1e-36, Organism=Drosophila melanogaster, GI28574878, Length=240, Percent_Identity=37.0833333333333, Blast_Score=149, Evalue=6e-36, Organism=Drosophila melanogaster, GI24665814, Length=240, Percent_Identity=37.0833333333333, Blast_Score=149, Evalue=8e-36, Organism=Drosophila melanogaster, GI18859657, Length=255, Percent_Identity=33.7254901960784, Blast_Score=146, Evalue=5e-35, Organism=Drosophila melanogaster, GI20129423, Length=278, Percent_Identity=32.7338129496403, Blast_Score=146, Evalue=6e-35, Organism=Drosophila melanogaster, GI281360146, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI281360138, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI281360144, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI281360140, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI281360136, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI24644411, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI281360142, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI21357333, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=1e-34, Organism=Drosophila melanogaster, GI24581396, Length=229, Percent_Identity=37.5545851528384, Blast_Score=139, Evalue=9e-33, Organism=Drosophila melanogaster, GI20129529, Length=231, Percent_Identity=35.0649350649351, Blast_Score=131, Evalue=2e-30, Organism=Drosophila melanogaster, GI24639486, Length=264, Percent_Identity=34.0909090909091, Blast_Score=127, Evalue=2e-29, Organism=Drosophila melanogaster, GI28571849, Length=278, Percent_Identity=34.1726618705036, Blast_Score=125, Evalue=8e-29, Organism=Drosophila melanogaster, GI28571847, Length=278, Percent_Identity=34.1726618705036, Blast_Score=125, Evalue=8e-29, Organism=Drosophila melanogaster, GI45554047, Length=167, Percent_Identity=35.9281437125749, Blast_Score=118, Evalue=2e-26, Organism=Drosophila melanogaster, GI28573181, Length=167, Percent_Identity=32.3353293413174, Blast_Score=67, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR009010 - InterPro: IPR003593 - InterPro: IPR005938 - InterPro: IPR003959 - InterPro: IPR003960 - InterPro: IPR003338 - InterPro: IPR004201 - InterPro: IPR015415 [H]
Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]
EC number: 3.4.24.- [C]
Molecular weight: Translated: 77123; Mature: 76992
Theoretical pI: Translated: 4.71; Mature: 4.71
Prosite motif: PS00674 AAA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 1.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 0.8 %Met (Mature Protein) 1.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTEAGLSEREPNLSHLRLTARLNTAALDSRRGVVRLHPEVIAALGIREWDAVSLTGARTT CCCCCCCCCCCCCCEEEEEEECCHHHHHCCCCEEEECHHHHHHHCCCCCCCEEECCCCCE AAVVGIAPPGTPTGTALLDDVTLSNAGLPENSSVIVAPVTVYGARSVTVSGSRLATNSIS EEEEEECCCCCCCCCCEEECEEECCCCCCCCCCEEEEEEEEECCEEEEECCCEEECCCCC PATLRQALLGKVMTVGDTVSLLPRDLGPGTSTSSATTALASSVGITWTSELLTVTSVDPP HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEECCEEEEEECCCC GTVSIQPNSSVTWGDGPAPKAASAGPTDGAAVGEATVTTPSVDRPAVSFDDLKGSHAQAG CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCHH RLTEWLKLSLDEPSLLETLGATAHLGVLVSGPAGVGKATLVRTVCAQRRLVELDGPEVGA HHHHHHHCCCCCCHHHHHHCCHHEEEEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCE LHAEDRLNRVSSAVSTVRDGGGVLLISDIDALLPATPEPVGTLILTELRTAVATPGVAFV ECHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEE ATSARPDGVDARLRDPDLCDRELGLSLPDAATRKELLEVLLRSVPAQELHLDEIAGRTPG EECCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC FVIADLCALVREAALRAAARASADGAPPQLTQADLTGALTVIRPLSRSATEEVSVGSVTL HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE ADVGDMTETKQALTEAVLWPLQHPDTFERLGIEPPRGVLLYGPPGCGKTFVVRALASSGR CCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCC LSVHAVKGAELMDKWVGASEKAVRELFRRARDSAPSLVFLDEIDALAPRRGQSFDSGVTD EEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCHHH RVVASLLTELDGIEPMCNVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAEARREILR HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHH TAGKSVPLADDVDLDTLAAGLDGYSAADCVALLREAAMTAMRRSIDAADVTAADVEAARQ HCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH TVRPSLDPLQVDTLRAFAENR HHCCCCCCCHHHHHHHHHCCC >Mature Secondary Structure TEAGLSEREPNLSHLRLTARLNTAALDSRRGVVRLHPEVIAALGIREWDAVSLTGARTT CCCCCCCCCCCCCEEEEEEECCHHHHHCCCCEEEECHHHHHHHCCCCCCCEEECCCCCE AAVVGIAPPGTPTGTALLDDVTLSNAGLPENSSVIVAPVTVYGARSVTVSGSRLATNSIS EEEEEECCCCCCCCCCEEECEEECCCCCCCCCCEEEEEEEEECCEEEEECCCEEECCCCC PATLRQALLGKVMTVGDTVSLLPRDLGPGTSTSSATTALASSVGITWTSELLTVTSVDPP HHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCEEECCEEEEEECCCC GTVSIQPNSSVTWGDGPAPKAASAGPTDGAAVGEATVTTPSVDRPAVSFDDLKGSHAQAG CEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCHHHCCCCCCCHH RLTEWLKLSLDEPSLLETLGATAHLGVLVSGPAGVGKATLVRTVCAQRRLVELDGPEVGA HHHHHHHCCCCCCHHHHHHCCHHEEEEEEECCCCCCHHHHHHHHHHHCCEEECCCCCCCE LHAEDRLNRVSSAVSTVRDGGGVLLISDIDALLPATPEPVGTLILTELRTAVATPGVAFV ECHHHHHHHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEE ATSARPDGVDARLRDPDLCDRELGLSLPDAATRKELLEVLLRSVPAQELHLDEIAGRTPG EECCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC FVIADLCALVREAALRAAARASADGAPPQLTQADLTGALTVIRPLSRSATEEVSVGSVTL HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEE ADVGDMTETKQALTEAVLWPLQHPDTFERLGIEPPRGVLLYGPPGCGKTFVVRALASSGR CCCCCHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCC LSVHAVKGAELMDKWVGASEKAVRELFRRARDSAPSLVFLDEIDALAPRRGQSFDSGVTD EEEEEECCHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEECCHHHHCCCCCCCCCCCHHH RVVASLLTELDGIEPMCNVVVLGATNRPDLIDPALLRPGRLERLVFVEPPDAEARREILR HHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHH TAGKSVPLADDVDLDTLAAGLDGYSAADCVALLREAAMTAMRRSIDAADVTAADVEAARQ HCCCCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH TVRPSLDPLQVDTLRAFAENR HHCCCCCCCHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 9389475 [H]