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The map label for this gene is lldR [H]

Identifier: 108797488

GI number: 108797488

Start: 563344

End: 564072

Strand: Reverse

Name: lldR [H]

Synonym: Mmcs_0508

Alternate gene names: 108797488

Gene position: 564072-563344 (Counterclockwise)

Preceding gene: 108797494

Following gene: 108797487

Centisome position: 9.89

GC content: 73.8

Gene sequence:

>729_bases
ATGCCCGACGATTTCCTGCTGCGACCTCTCGACGCCCCACCGGCGTATGCCGCCGTCGTCGAGCGGGTCCGGCGCGCGGT
CGCGCTCGGGGTGTTGCTGCCCGGCGACCGGTTGCCGTCCGAGCGGGCGCTGGCCGAAGGGCTCGGCGTCTCGAGGGTCA
CGGTGCGCGAGGCGCTGCGGGTCTTGCAGGGTGAACGGCTGCTGATCACCAAACGGGGCAACGGCGGCACGGTGGTGGCG
CCCACGGTCGCCCGCCTCGGGGACGATCCGGGCGGCGTGGACTACGGCCGCCGACTCGACGAGGTCTTCGAGTTGCGGCT
GGCCGTCGAGTCGATGGCCGCCCGCCTCGCGGCCCGGCGGGGCCGGCCGGAGGGCCTGCGGTGGCTGGACTCCTGCCAGG
AGGCGTTGCGGGCCAGCTCCGACGTGCACACCTTCCGGCGCGCCGACTCCGAGTTCCACCTGGCGGTCGCCCGGTTGAGC
GGAAACAGCATGCTCAGCCAGGTGATCGAGGATGCCCGCGCCGCGGCCTTCTCCCGGCTGGACCGCCAGGACTTCGCCGT
CATCTACGAATCCTCGATCCGCGGCCACGCCGCGGTGATCGAGGCCATCCGCAACGCGGACCCCGACGGCGCGGCGGCGG
CGATGGCCGCCCATATCGAGGAGGCCCGCGACGAAGTGGCGGCGGTGCTGTCCACGCGTGAGTCGCCGGAGGTCCGCTCG
GCCGGCTGA

Upstream 100 bases:

>100_bases
GCTCAACCCGCAGACACCGATCAGTGGCGTTACTTCCGAATTCATGGTCTTAGTTTCATACCACCAGACTTCGGGACCGC
GCCCGGTTACGCTGCAAAAG

Downstream 100 bases:

>100_bases
GCGCTGCCGGAGCGGCCGGTAACGTCGAATCGTGAGCATCCGCCCGCTGCGCCAGTCGGTGCGGCCGAGCCCCGTCTTCC
TCGCCGTGGTGGCGATCACC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MPDDFLLRPLDAPPAYAAVVERVRRAVALGVLLPGDRLPSERALAEGLGVSRVTVREALRVLQGERLLITKRGNGGTVVA
PTVARLGDDPGGVDYGRRLDEVFELRLAVESMAARLAARRGRPEGLRWLDSCQEALRASSDVHTFRRADSEFHLAVARLS
GNSMLSQVIEDARAAAFSRLDRQDFAVIYESSIRGHAAVIEAIRNADPDGAAAAMAAHIEEARDEVAAVLSTRESPEVRS
AG

Sequences:

>Translated_242_residues
MPDDFLLRPLDAPPAYAAVVERVRRAVALGVLLPGDRLPSERALAEGLGVSRVTVREALRVLQGERLLITKRGNGGTVVA
PTVARLGDDPGGVDYGRRLDEVFELRLAVESMAARLAARRGRPEGLRWLDSCQEALRASSDVHTFRRADSEFHLAVARLS
GNSMLSQVIEDARAAAFSRLDRQDFAVIYESSIRGHAAVIEAIRNADPDGAAAAMAAHIEEARDEVAAVLSTRESPEVRS
AG
>Mature_241_residues
PDDFLLRPLDAPPAYAAVVERVRRAVALGVLLPGDRLPSERALAEGLGVSRVTVREALRVLQGERLLITKRGNGGTVVAP
TVARLGDDPGGVDYGRRLDEVFELRLAVESMAARLAARRGRPEGLRWLDSCQEALRASSDVHTFRRADSEFHLAVARLSG
NSMLSQVIEDARAAAFSRLDRQDFAVIYESSIRGHAAVIEAIRNADPDGAAAAMAAHIEEARDEVAAVLSTRESPEVRSA
G

Specific function: May be a regulatory protein for the LCT genes [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790032, Length=218, Percent_Identity=34.4036697247706, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87082208, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI48994955, Length=201, Percent_Identity=31.8407960199005, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789353, Length=179, Percent_Identity=29.608938547486, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786303, Length=219, Percent_Identity=28.7671232876712, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789621, Length=227, Percent_Identity=28.6343612334802, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790780, Length=218, Percent_Identity=28.8990825688073, Blast_Score=64, Evalue=6e-12,
Organism=Escherichia coli, GI1786950, Length=65, Percent_Identity=47.6923076923077, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26097; Mature: 25966

Theoretical pI: Translated: 6.16; Mature: 6.16

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDFLLRPLDAPPAYAAVVERVRRAVALGVLLPGDRLPSERALAEGLGVSRVTVREALR
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHH
VLQGERLLITKRGNGGTVVAPTVARLGDDPGGVDYGRRLDEVFELRLAVESMAARLAARR
HHCCCEEEEEECCCCCEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRPEGLRWLDSCQEALRASSDVHTFRRADSEFHLAVARLSGNSMLSQVIEDARAAAFSRL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHEEEEEHHCCHHHHHHHHHHHHHHHHHHH
DRQDFAVIYESSIRGHAAVIEAIRNADPDGAAAAMAAHIEEARDEVAAVLSTRESPEVRS
CHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AG
CC
>Mature Secondary Structure 
PDDFLLRPLDAPPAYAAVVERVRRAVALGVLLPGDRLPSERALAEGLGVSRVTVREALR
CCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHH
VLQGERLLITKRGNGGTVVAPTVARLGDDPGGVDYGRRLDEVFELRLAVESMAARLAARR
HHCCCEEEEEECCCCCEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRPEGLRWLDSCQEALRASSDVHTFRRADSEFHLAVARLSGNSMLSQVIEDARAAAFSRL
CCCHHHHHHHHHHHHHHCCHHHHHHHHCCCHHEEEEEHHCCHHHHHHHHHHHHHHHHHHH
DRQDFAVIYESSIRGHAAVIEAIRNADPDGAAAAMAAHIEEARDEVAAVLSTRESPEVRS
CHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407843; 8041620; 9278503 [H]