BacMap

Definition	Mycobacterium sp. MCS chromosome, complete genome.
Accession	NC_008146
Length	5,705,448

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The map label for this gene is yqjQ [H]

Identifier: 108797460

GI number: 108797460

Start: 535217

End: 535993

Strand: Direct

Name: yqjQ [H]

Synonym: Mmcs_0480

Alternate gene names: 108797460

Gene position: 535217-535993 (Clockwise)

Preceding gene: 108797459

Following gene: 108797461

Centisome position: 9.38

GC content: 70.91

Gene sequence:

>777_bases
ATGCCCCGTCCCGTCGTCCTGATCACCGGACCGACCTCCGGCCTCGGTGAAGGCTTCGCGCGTCGCTACGCCGCCGACGG
CCACGACCTCGTCCTCGTCGCCCGCGACGAAGCCCGCCTCGAAGCGCTCGCGGGGGCACTACGCGCCGAGACCGGCGCCG
GTGTCGAGGTGCTACCCGCCGACCTCGCCGACGCCGATGACCGCGCCAAGGTCGCCGAACGGCTCTCCTCGCGCGTCCGG
GTGCTCGTCAACAACGCCGGATTCGGCACCTCCGGGGAGTTCTGGACCGCCGACTACCAGGTGTTGCAGTCCCAGCTCGA
CGTCAACGTCACCGCGGTCATGCAGCTCACCCACGCCGCCCTCCCGCCGATGCTCGACGCGCACGCCGGCACCGTCATCA
ACGTCGCGAGCGTGTCGGGTCTGCTGCCCGGCCGCGGGTCGACCTACTCGGCCTCCAAGGCGTGGGTGATCGCCTTCTCC
GAAGGACTCGCCAACGGGCTCGGCGGCACCGGCGTCGGCGTGCACGCCCTGTGTCCCGGATTCATCCACACCGAATTCCA
CCAGCGGGCCGGCATCGAGATGTCCGGCCTGCCGTCGTGGATGTGGCTCGAAGTCGACGACGTCGTCGGTGACTGTCTCA
CCGCCGTCGCCAAGGACAGGGTCGTCATCGTGCCCGGTGTGCAGTACAAGGCCATGACCACCGTCAGCCGCCTGGTCCCG
CGCCACCTCGTGCGCGCCATGACGAGGACCGTGGGCCGCGGCCGCGGCCGCACCTGA

Upstream 100 bases:

>100_bases
CGGTCCGCCGGCGGCACGCCCTGACACCGCACGCCGGACCCCGCCGGCGCGCAACGGGCACCAGTCGGCCAACTTCCAGC
GCTGAGTGCGCTGCTCCGCG

Downstream 100 bases:

>100_bases
TCGCCGGTGCGCGCGCTCGTCGCCGTCGTCGTGACGGTTCTGCTCGTTGCGGTCACCGGCTGCTCGAAGGCCGAGGGCCG
GTCCGACACCTACTCCGCGC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MPRPVVLITGPTSGLGEGFARRYAADGHDLVLVARDEARLEALAGALRAETGAGVEVLPADLADADDRAKVAERLSSRVR
VLVNNAGFGTSGEFWTADYQVLQSQLDVNVTAVMQLTHAALPPMLDAHAGTVINVASVSGLLPGRGSTYSASKAWVIAFS
EGLANGLGGTGVGVHALCPGFIHTEFHQRAGIEMSGLPSWMWLEVDDVVGDCLTAVAKDRVVIVPGVQYKAMTTVSRLVP
RHLVRAMTRTVGRGRGRT

Sequences:

>Translated_258_residues
MPRPVVLITGPTSGLGEGFARRYAADGHDLVLVARDEARLEALAGALRAETGAGVEVLPADLADADDRAKVAERLSSRVR
VLVNNAGFGTSGEFWTADYQVLQSQLDVNVTAVMQLTHAALPPMLDAHAGTVINVASVSGLLPGRGSTYSASKAWVIAFS
EGLANGLGGTGVGVHALCPGFIHTEFHQRAGIEMSGLPSWMWLEVDDVVGDCLTAVAKDRVVIVPGVQYKAMTTVSRLVP
RHLVRAMTRTVGRGRGRT
>Mature_257_residues
PRPVVLITGPTSGLGEGFARRYAADGHDLVLVARDEARLEALAGALRAETGAGVEVLPADLADADDRAKVAERLSSRVRV
LVNNAGFGTSGEFWTADYQVLQSQLDVNVTAVMQLTHAALPPMLDAHAGTVINVASVSGLLPGRGSTYSASKAWVIAFSE
GLANGLGGTGVGVHALCPGFIHTEFHQRAGIEMSGLPSWMWLEVDDVVGDCLTAVAKDRVVIVPGVQYKAMTTVSRLVPR
HLVRAMTRTVGRGRGRT

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705855, Length=240, Percent_Identity=25, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4557649, Length=183, Percent_Identity=31.6939890710383, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI142976729, Length=261, Percent_Identity=28.735632183908, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI40254992, Length=187, Percent_Identity=31.5508021390374, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI32483357, Length=193, Percent_Identity=30.0518134715026, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI20149619, Length=196, Percent_Identity=33.6734693877551, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI210032110, Length=238, Percent_Identity=27.3109243697479, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226371731, Length=186, Percent_Identity=26.8817204301075, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI25282469, Length=280, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI223718074, Length=198, Percent_Identity=36.3636363636364, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI7657478, Length=206, Percent_Identity=30.5825242718447, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI150247226, Length=205, Percent_Identity=32.6829268292683, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=28.9340101522843, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI31542939, Length=191, Percent_Identity=30.3664921465969, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI186928839, Length=219, Percent_Identity=30.1369863013699, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI210032112, Length=158, Percent_Identity=28.4810126582279, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI40548397, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI214010158, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI214010156, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI22758144, Length=209, Percent_Identity=27.7511961722488, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=1e-10,
Organism=Escherichia coli, GI1787820, Length=191, Percent_Identity=34.5549738219895, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI87082100, Length=190, Percent_Identity=32.6315789473684, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1787335, Length=199, Percent_Identity=29.1457286432161, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082160, Length=220, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1786701, Length=197, Percent_Identity=31.4720812182741, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71994600, Length=205, Percent_Identity=34.6341463414634, Blast_Score=94, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71994604, Length=204, Percent_Identity=30.8823529411765, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17508895, Length=259, Percent_Identity=27.027027027027, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555706, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=221, Percent_Identity=28.0542986425339, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=232, Percent_Identity=29.3103448275862, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=266, Percent_Identity=27.4436090225564, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=213, Percent_Identity=28.6384976525822, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17507613, Length=213, Percent_Identity=28.6384976525822, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17551412, Length=228, Percent_Identity=28.0701754385965, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=227, Percent_Identity=26.8722466960352, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561402, Length=189, Percent_Identity=25.9259259259259, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147288, Length=185, Percent_Identity=30.2702702702703, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17562904, Length=208, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=199, Percent_Identity=34.6733668341709, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319635, Length=185, Percent_Identity=29.1891891891892, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=185, Percent_Identity=27.5675675675676, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI23397609, Length=196, Percent_Identity=36.734693877551, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571526, Length=202, Percent_Identity=34.1584158415842, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=31.5789473684211, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357041, Length=202, Percent_Identity=31.6831683168317, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584752, Length=202, Percent_Identity=30.1980198019802, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=31.3513513513514, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=31.3513513513514, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=31.3131313131313, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644339, Length=202, Percent_Identity=30.1980198019802, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28574402, Length=210, Percent_Identity=29.0476190476191, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584744, Length=210, Percent_Identity=29.0476190476191, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355319, Length=192, Percent_Identity=28.6458333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651139, Length=193, Percent_Identity=34.7150259067358, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581726, Length=238, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI116007236, Length=218, Percent_Identity=27.5229357798165, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24639444, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24643142, Length=215, Percent_Identity=27.906976744186, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27190; Mature: 27059

Theoretical pI: Translated: 7.22; Mature: 7.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPVVLITGPTSGLGEGFARRYAADGHDLVLVARDEARLEALAGALRAETGAGVEVLPA
CCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEC
DLADADDRAKVAERLSSRVRVLVNNAGFGTSGEFWTADYQVLQSQLDVNVTAVMQLTHAA
CCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHH
LPPMLDAHAGTVINVASVSGLLPGRGSTYSASKAWVIAFSEGLANGLGGTGVGVHALCPG
CCCCHHCCCCCEEEEHHHCCCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHCCH
FIHTEFHQRAGIEMSGLPSWMWLEVDDVVGDCLTAVAKDRVVIVPGVQYKAMTTVSRLVP
HHHHHHHHHCCCEECCCCCEEEEEHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
RHLVRAMTRTVGRGRGRT
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PRPVVLITGPTSGLGEGFARRYAADGHDLVLVARDEARLEALAGALRAETGAGVEVLPA
CCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEC
DLADADDRAKVAERLSSRVRVLVNNAGFGTSGEFWTADYQVLQSQLDVNVTAVMQLTHAA
CCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCEEHHHHHHHHHHHCCCHHHHHHHHHHH
LPPMLDAHAGTVINVASVSGLLPGRGSTYSASKAWVIAFSEGLANGLGGTGVGVHALCPG
CCCCHHCCCCCEEEEHHHCCCCCCCCCCCCCCCEEEEEECCHHHCCCCCCCCCHHHHCCH
FIHTEFHQRAGIEMSGLPSWMWLEVDDVVGDCLTAVAKDRVVIVPGVQYKAMTTVSRLVP
HHHHHHHHHCCCEECCCCCEEEEEHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHH
RHLVRAMTRTVGRGRGRT
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]