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The map label for this gene is fadE25 [H]

Identifier: 108797346

GI number: 108797346

Start: 407239

End: 409431

Strand: Reverse

Name: fadE25 [H]

Synonym: Mmcs_0366

Alternate gene names: 108797346

Gene position: 409431-407239 (Counterclockwise)

Preceding gene: 108797347

Following gene: 108797345

Centisome position: 7.18

GC content: 68.95

Gene sequence:

>2193_bases
ATGCCCATCGCAATCACCGAAGAGCACAACGATCTCGCCGACTCGGTGCGATCCCTGGTGGCGCGGGTGGCGCCGTCCGA
AATGCTCCACGATGCGCTCGAGAACCCGATTCCCAACCCGCCCCCGTTCTGGCGGGCGGCAGCGGAACAGGGACTGCAGG
GGGTGCACCTTCCCGAATCCGTGGGCGGGCAGGGCTTCGGCATCCTCGAGCTCGCGATCGTGCTCGCCGAATTCGGTTAC
GGCGCAGTGCCCGGCCCGTTCGTACCGTCGGCGATCGCCGGTGCGCTGATCGCCGCGCACGATCCCGACGCCAAGGTCCT
CAGCGGGCTCGCCTCGGGTGACGTCATCGCCGCCTACGCGATCGACTCGGGCCTGACCGCCACCCGGCACGGCGACGGGC
TGGTCATCCGCGGTGAGGTGCGGGCCGTTCCCGCCGCCGCGCAGGCCTCCGTGCTGGTTCTCCCGGTCGCCATCGACTCG
AGTGACGAATGGGTGGTCCTCGACGCCGGCCAACTGGAGATCGAACCGGTCGCGAGCATCGACCCCCTCCGTCCGGTGGC
CCACGTCCGCGCCAACGCCGTCGACGTCGCCGACGACCGGGTGCTGAGCAACCTCACGCCCGCGCTGGCTCGGGCGCTCA
TCGTCACGCTGCTGTCCGCCGAGGCGATCGGGGTGGCCCGGTGGGCGACCGACACCGCATCCGGCTACGCCAAGATCCGC
GAACAATTCGGCAGGCCGATCGGACAGTTCCAGGCCATCAAGCACAAATGCGCCGACATGATCGCCCAGACCGAGCGGGC
CACCGCCGCGGTGTGGGATGCCGCCCGCGCCCTCGACGAGGTTCGCGAGAACGTCACGGACGAGCCGCATTTCGAGTTCG
CCGCCGCGGTCGCGGCCACGCTGGCGCCGACCGCCGCCCAGCACTGCGTCCAGGAGTGCATCCAGGTGCACGGCGGCATC
GGGTTCACCTGGGAACACGACACCAACGTCTACTACCGCCGCGCGCTGGTGCTCGCCGCCGCGTTCGGACGCCGCGCCGA
CTACCCGCAGCACATCGTCGACACCGCGACGACCACCGGGATGCGTCCGATCAACATCGACCTCGACCCCGACACCGAGA
AGCTTCGTGAGGAGATCCGCGCCGAGGTCGCCGCGCTCAAGGCGCTGCCGCGCGAGGAGCGCACCGTCGCGATCGCCGAG
GGCGGCTGGGTGGTGCCGCACCTGCCCACCCCGTGGGGTCGCGGCGCCGGCCCGGTCGAGCAGATCCTCATCGCCCAGGA
GTTCGCCGCCGGCCGGGTCAAGCGCCCCCAGATGGGGATCGCCGCGTGGCTGATCCCGTCGATCGTGGCGTTCGGCACCG
ACGAGCAGAAGCAGCGCTTCCTGCCGCCGACGTTCCGTGGCGAGATGATCTGGTGCCAGCTGTTCTCCGAGCCGGGCGCC
GGATCCGATCTGGCGAGCCTGACCACGAAGGCCACCAAGGTCGACGGCGGCTGGCGCGTCACCGGCCAGAAGATCTGGAC
CACCGGCGCGCAGTACTCCCAGTGGGGGGCGCTGCTGGCGAGAACGGATCCGAATGCCCCGAAACACAACGGCATCACCT
ACTTCCTGCTCGACATGAACAGTGAAGGCGTCGAGGTCAAACCGCTGCGCGAACTGACCGGCAACGCGATGTTCAACACG
GTCTTCATCGACGACGTGTTCATCCCGGACGAACTGGTGGTCGGTGAGGTCAACCGCGGCTGGGAGGTCAGCCGCAACAC
GTTGACCAACGAGCGGGTCTCGATCGGCAGCAGCGAGCCGCCGTTCCTGGCCACGCTCGACGGTTTCGTCGAGTTCATCC
GCGACGGGCACTTCGACCAGATCGGCCAGAACAAGGCCGGTCAGCTGATCGCCGAAGGGCACGCCGCCAAACTGCTCAAC
CTGCGCTCGACGCTGCTCACCCTGGCCGGCGGCGACGCGATGCCGTCGGCCGCGATCTCCAAGTTGCTGTCGATGAAAAC
CGGTCAGGGGTACGCGGAGTTCGCGGTGTCGTCGTTCGGCACCGACGGCGTGCTCGCCGAACCGGAGTCACTGGAGTTCA
AGTGGGTGGAGTACCTGCTGGGCAGCCGGGCGACGACCATCTACGGCGGCACCTCGGAGGTGCAGCTCAACATCATCGCC
GAGCGCCTGCTCGGGTTGCCGCGCGATCCGTAA

Upstream 100 bases:

>100_bases
CCGCGATGGTCGACCAGCTCGCCGATCCCCGGTTGTACTGACTCGCACCGTATGTAATGTGGCTCCCAACCAAGCGGTTA
ATAGGGAAGGCAACGAAGCT

Downstream 100 bases:

>100_bases
TCCGCTGGGGGGTTTGGCGGGTCGACGGGGCGGGAACAACAGGCGATCAGCGTCCGTTGAGTGCTGTGCAGTTCCCCGCG
ACGACTTAAGAGGCAGCCAT

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 729

Protein sequence:

>730_residues
MPIAITEEHNDLADSVRSLVARVAPSEMLHDALENPIPNPPPFWRAAAEQGLQGVHLPESVGGQGFGILELAIVLAEFGY
GAVPGPFVPSAIAGALIAAHDPDAKVLSGLASGDVIAAYAIDSGLTATRHGDGLVIRGEVRAVPAAAQASVLVLPVAIDS
SDEWVVLDAGQLEIEPVASIDPLRPVAHVRANAVDVADDRVLSNLTPALARALIVTLLSAEAIGVARWATDTASGYAKIR
EQFGRPIGQFQAIKHKCADMIAQTERATAAVWDAARALDEVRENVTDEPHFEFAAAVAATLAPTAAQHCVQECIQVHGGI
GFTWEHDTNVYYRRALVLAAAFGRRADYPQHIVDTATTTGMRPINIDLDPDTEKLREEIRAEVAALKALPREERTVAIAE
GGWVVPHLPTPWGRGAGPVEQILIAQEFAAGRVKRPQMGIAAWLIPSIVAFGTDEQKQRFLPPTFRGEMIWCQLFSEPGA
GSDLASLTTKATKVDGGWRVTGQKIWTTGAQYSQWGALLARTDPNAPKHNGITYFLLDMNSEGVEVKPLRELTGNAMFNT
VFIDDVFIPDELVVGEVNRGWEVSRNTLTNERVSIGSSEPPFLATLDGFVEFIRDGHFDQIGQNKAGQLIAEGHAAKLLN
LRSTLLTLAGGDAMPSAAISKLLSMKTGQGYAEFAVSSFGTDGVLAEPESLEFKWVEYLLGSRATTIYGGTSEVQLNIIA
ERLLGLPRDP

Sequences:

>Translated_730_residues
MPIAITEEHNDLADSVRSLVARVAPSEMLHDALENPIPNPPPFWRAAAEQGLQGVHLPESVGGQGFGILELAIVLAEFGY
GAVPGPFVPSAIAGALIAAHDPDAKVLSGLASGDVIAAYAIDSGLTATRHGDGLVIRGEVRAVPAAAQASVLVLPVAIDS
SDEWVVLDAGQLEIEPVASIDPLRPVAHVRANAVDVADDRVLSNLTPALARALIVTLLSAEAIGVARWATDTASGYAKIR
EQFGRPIGQFQAIKHKCADMIAQTERATAAVWDAARALDEVRENVTDEPHFEFAAAVAATLAPTAAQHCVQECIQVHGGI
GFTWEHDTNVYYRRALVLAAAFGRRADYPQHIVDTATTTGMRPINIDLDPDTEKLREEIRAEVAALKALPREERTVAIAE
GGWVVPHLPTPWGRGAGPVEQILIAQEFAAGRVKRPQMGIAAWLIPSIVAFGTDEQKQRFLPPTFRGEMIWCQLFSEPGA
GSDLASLTTKATKVDGGWRVTGQKIWTTGAQYSQWGALLARTDPNAPKHNGITYFLLDMNSEGVEVKPLRELTGNAMFNT
VFIDDVFIPDELVVGEVNRGWEVSRNTLTNERVSIGSSEPPFLATLDGFVEFIRDGHFDQIGQNKAGQLIAEGHAAKLLN
LRSTLLTLAGGDAMPSAAISKLLSMKTGQGYAEFAVSSFGTDGVLAEPESLEFKWVEYLLGSRATTIYGGTSEVQLNIIA
ERLLGLPRDP
>Mature_729_residues
PIAITEEHNDLADSVRSLVARVAPSEMLHDALENPIPNPPPFWRAAAEQGLQGVHLPESVGGQGFGILELAIVLAEFGYG
AVPGPFVPSAIAGALIAAHDPDAKVLSGLASGDVIAAYAIDSGLTATRHGDGLVIRGEVRAVPAAAQASVLVLPVAIDSS
DEWVVLDAGQLEIEPVASIDPLRPVAHVRANAVDVADDRVLSNLTPALARALIVTLLSAEAIGVARWATDTASGYAKIRE
QFGRPIGQFQAIKHKCADMIAQTERATAAVWDAARALDEVRENVTDEPHFEFAAAVAATLAPTAAQHCVQECIQVHGGIG
FTWEHDTNVYYRRALVLAAAFGRRADYPQHIVDTATTTGMRPINIDLDPDTEKLREEIRAEVAALKALPREERTVAIAEG
GWVVPHLPTPWGRGAGPVEQILIAQEFAAGRVKRPQMGIAAWLIPSIVAFGTDEQKQRFLPPTFRGEMIWCQLFSEPGAG
SDLASLTTKATKVDGGWRVTGQKIWTTGAQYSQWGALLARTDPNAPKHNGITYFLLDMNSEGVEVKPLRELTGNAMFNTV
FIDDVFIPDELVVGEVNRGWEVSRNTLTNERVSIGSSEPPFLATLDGFVEFIRDGHFDQIGQNKAGQLIAEGHAAKLLNL
RSTLLTLAGGDAMPSAAISKLLSMKTGQGYAEFAVSSFGTDGVLAEPESLEFKWVEYLLGSRATTIYGGTSEVQLNIIAE
RLLGLPRDP

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=289, Percent_Identity=29.4117647058824, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4501859, Length=327, Percent_Identity=26.2996941896024, Blast_Score=90, Evalue=7e-18,
Organism=Homo sapiens, GI4557231, Length=343, Percent_Identity=26.2390670553936, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI187960098, Length=343, Percent_Identity=26.2390670553936, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI226958414, Length=321, Percent_Identity=26.1682242990654, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI226958412, Length=320, Percent_Identity=26.25, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4501857, Length=316, Percent_Identity=25.3164556962025, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI7656849, Length=300, Percent_Identity=26, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI4557235, Length=288, Percent_Identity=25.6944444444444, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI76496475, Length=288, Percent_Identity=25.6944444444444, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI21361497, Length=160, Percent_Identity=31.25, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI211971008, Length=299, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=9e-13,
Organism=Homo sapiens, GI48976061, Length=299, Percent_Identity=26.0869565217391, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI87081958, Length=295, Percent_Identity=28.4745762711864, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI1786223, Length=146, Percent_Identity=29.4520547945205, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17508101, Length=343, Percent_Identity=28.8629737609329, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=344, Percent_Identity=26.7441860465116, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=407, Percent_Identity=26.044226044226, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17569725, Length=339, Percent_Identity=26.2536873156342, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17551932, Length=285, Percent_Identity=25.9649122807018, Blast_Score=87, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=285, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17534899, Length=289, Percent_Identity=25.9515570934256, Blast_Score=85, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=234, Percent_Identity=26.0683760683761, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32563615, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538396, Length=240, Percent_Identity=28.3333333333333, Blast_Score=75, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24646207, Length=298, Percent_Identity=27.1812080536913, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356377, Length=289, Percent_Identity=25.9515570934256, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24666513, Length=404, Percent_Identity=25, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355753, Length=327, Percent_Identity=27.5229357798165, Blast_Score=78, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24660351, Length=295, Percent_Identity=24.7457627118644, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363737, Length=159, Percent_Identity=30.188679245283, Blast_Score=73, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 78229; Mature: 78097

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIAITEEHNDLADSVRSLVARVAPSEMLHDALENPIPNPPPFWRAAAEQGLQGVHLPES
CCEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCHH
VGGQGFGILELAIVLAEFGYGAVPGPFVPSAIAGALIAAHDPDAKVLSGLASGDVIAAYA
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHEEECCCCCHHHHHHCCCCCEEEEEE
IDSGLTATRHGDGLVIRGEVRAVPAAAQASVLVLPVAIDSSDEWVVLDAGQLEIEPVASI
ECCCCEEEECCCCEEEECCCEECCCCCCCEEEEEEEEECCCCCEEEEECCCEEECCCCCC
DPLRPVAHVRANAVDVADDRVLSNLTPALARALIVTLLSAEAIGVARWATDTASGYAKIR
CCCCHHHHHHCCCEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EQFGRPIGQFQAIKHKCADMIAQTERATAAVWDAARALDEVRENVTDEPHFEFAAAVAAT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LAPTAAQHCVQECIQVHGGIGFTWEHDTNVYYRRALVLAAAFGRRADYPQHIVDTATTTG
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
MRPINIDLDPDTEKLREEIRAEVAALKALPREERTVAIAEGGWVVPHLPTPWGRGAGPVE
CCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCCCCCCCHHH
QILIAQEFAAGRVKRPQMGIAAWLIPSIVAFGTDEQKQRFLPPTFRGEMIWCQLFSEPGA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEEEEECCCCC
GSDLASLTTKATKVDGGWRVTGQKIWTTGAQYSQWGALLARTDPNAPKHNGITYFLLDMN
CCHHHHHHHHHEECCCCEEEECCEEEECCCCHHHHCEEEEECCCCCCCCCCEEEEEEECC
SEGVEVKPLRELTGNAMFNTVFIDDVFIPDELVVGEVNRGWEVSRNTLTNERVSIGSSEP
CCCCEECCHHHHCCCCEEEEEEEECEECCCCEEEECCCCCCCCCCCCCCCCCEECCCCCC
PFLATLDGFVEFIRDGHFDQIGQNKAGQLIAEGHAAKLLNLRSTLLTLAGGDAMPSAAIS
CEEHHHHHHHHHHHCCCHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHH
KLLSMKTGQGYAEFAVSSFGTDGVLAEPESLEFKWVEYLLGSRATTIYGGTSEVQLNIIA
HHHHHCCCCCHHHHHHHHCCCCCCEECCCCCHHHHHHHHHCCCCEEEECCCCCEEHHHHH
ERLLGLPRDP
HHHHCCCCCC
>Mature Secondary Structure 
PIAITEEHNDLADSVRSLVARVAPSEMLHDALENPIPNPPPFWRAAAEQGLQGVHLPES
CEEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCHH
VGGQGFGILELAIVLAEFGYGAVPGPFVPSAIAGALIAAHDPDAKVLSGLASGDVIAAYA
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHEEECCCCCHHHHHHCCCCCEEEEEE
IDSGLTATRHGDGLVIRGEVRAVPAAAQASVLVLPVAIDSSDEWVVLDAGQLEIEPVASI
ECCCCEEEECCCCEEEECCCEECCCCCCCEEEEEEEEECCCCCEEEEECCCEEECCCCCC
DPLRPVAHVRANAVDVADDRVLSNLTPALARALIVTLLSAEAIGVARWATDTASGYAKIR
CCCCHHHHHHCCCEECHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
EQFGRPIGQFQAIKHKCADMIAQTERATAAVWDAARALDEVRENVTDEPHFEFAAAVAAT
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LAPTAAQHCVQECIQVHGGIGFTWEHDTNVYYRRALVLAAAFGRRADYPQHIVDTATTTG
HHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
MRPINIDLDPDTEKLREEIRAEVAALKALPREERTVAIAEGGWVVPHLPTPWGRGAGPVE
CCEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEECCCCCCCCCCCCHHH
QILIAQEFAAGRVKRPQMGIAAWLIPSIVAFGTDEQKQRFLPPTFRGEMIWCQLFSEPGA
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCEEEEEEECCCCC
GSDLASLTTKATKVDGGWRVTGQKIWTTGAQYSQWGALLARTDPNAPKHNGITYFLLDMN
CCHHHHHHHHHEECCCCEEEECCEEEECCCCHHHHCEEEEECCCCCCCCCCEEEEEEECC
SEGVEVKPLRELTGNAMFNTVFIDDVFIPDELVVGEVNRGWEVSRNTLTNERVSIGSSEP
CCCCEECCHHHHCCCCEEEEEEEECEECCCCEEEECCCCCCCCCCCCCCCCCEECCCCCC
PFLATLDGFVEFIRDGHFDQIGQNKAGQLIAEGHAAKLLNLRSTLLTLAGGDAMPSAAIS
CEEHHHHHHHHHHHCCCHHHHCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHH
KLLSMKTGQGYAEFAVSSFGTDGVLAEPESLEFKWVEYLLGSRATTIYGGTSEVQLNIIA
HHHHHCCCCCHHHHHHHHCCCCCCEECCCCCHHHHHHHHHCCCCEEEECCCCCEEHHHHH
ERLLGLPRDP
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]