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The map label for this gene is ttuB [H]

Identifier: 108797344

GI number: 108797344

Start: 405471

End: 406757

Strand: Reverse

Name: ttuB [H]

Synonym: Mmcs_0364

Alternate gene names: 108797344

Gene position: 406757-405471 (Counterclockwise)

Preceding gene: 108797345

Following gene: 108797342

Centisome position: 7.13

GC content: 68.76

Gene sequence:

>1287_bases
ATGTGGCGCACCGTTCCCATCTTGATGGCGCTGTACTTCGTCAACTACCTGGACCGCACCAATCTCGGCATCGCGAGAGC
CGACATCAGCGCCCACCTGCAACTGTCGGCCACGATGTTCGGGTTCGCATCGGGCATCTTCTTCATCGGCTACGTCCTCG
TCGAGGTGCCGTCGAATCTCGCGCTGCACCGCTTCGGCGCCCGGCGGTGGCTGGCGCGTATCGCAGTGTCCTGGGGTCTG
GTCGTCGTCGCGATCGGCTTCGCGCCAAACGCCCCGACACTGCTGGCGCTGCGTTTCCTGCTCGGCGTGGCCGAAGCCGG
ACTGTTCCCCGGGGTGATCCTCTACCTCAGCCGCTGGTTCCCGACGGCGTACCGGGCGCGGGTCGTCGCGATGTTCATGC
TGGCCAGCCCGATCGCCGCGGCGGTCGGGACACCGGTCGGCGCCTGGCTCATCGACGTCGGTGACGGCCTGTTCGGGTTG
GCCGGCTGGCAGTTCATGATGATCTGTTCGGGCCTTCCGGCGATCGCGCTCGGCGTGGTGTGCTGGATTGCCCTGACGGA
CCGGCCCGCCGACGCGAACTGGCTACCCGACGACGAAAAACGTTGGCTCATAGGCGTTCTCGCGGCAGAAGAGCATGCCG
TGAGCAGCCGGTTCGACTTCCCGCTGCGCCGAGCGCTCAGAAGCCCGCGGGTGTGGGCGCTCGCGGTGGTGTACTTCGGC
GTCGCCTACGGGCTCTACGCGCTGGCGTTCTTCCTGCCGTCGATCATCGCCGGGTTCCGTGAGGATTTCGGGCTGACGCT
GTCCATCGAGCAGGTCGGGCTGATCACGGCGATCCCGTACGCGTTCGCGGCGGTGGCGATGTACCTGTGGTCGCGGCGCG
CGGACCGCACCGGCGCACACACCCGCCACGTCGCGGTCCCGATGCTACTGGGCGGGTTGGCGATCCCCGTGGCCCTGTAC
CTGGACAGCCCGGTGCTGGTGATGATCCCGGTGACGCTGGCCGCCATGGGGGTGTTCAGCGCGATCCCGAGCTTCTGGGC
GCTGCCGTCGCGGTTCCTGACCGGCGCCGCGGCCGCGGGCGGCATCGGGCTGATCAACTCGGTCGGCAACCTCGGCGGGT
TCGCCGCCCCGTACGTCACGGGTGCGCTCGACGACGCGCTGGGTTCGGCACGGGCGGGGATGTGGGCGGTCGGGTTGATG
ATGGTGATCTCGGCGGGCGTCGTATTCACACTGTCGAACGACCGGCTCAGCCCGTCGACGCCCGCAACTCCGCCAGCGCG
GCGCTGA

Upstream 100 bases:

>100_bases
CCGACTGCGCCTGACGTGACTGGGGCGGCGCCCGCCGCCCCATTACGATCACGGCGTGACCAGTGGCGGGCAGCGGGGGT
CCGCCACGGTGCGCAGGGTC

Downstream 100 bases:

>100_bases
GGCCGTCGAGAGTCGCACCGTCGGGTAGGTCGACGCGGTCCAGCCACGGGATGTCCGGCGTGCCCGTCACGCGGCCGCCG
AGGATTCCGCCCGCGATCGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MWRTVPILMALYFVNYLDRTNLGIARADISAHLQLSATMFGFASGIFFIGYVLVEVPSNLALHRFGARRWLARIAVSWGL
VVVAIGFAPNAPTLLALRFLLGVAEAGLFPGVILYLSRWFPTAYRARVVAMFMLASPIAAAVGTPVGAWLIDVGDGLFGL
AGWQFMMICSGLPAIALGVVCWIALTDRPADANWLPDDEKRWLIGVLAAEEHAVSSRFDFPLRRALRSPRVWALAVVYFG
VAYGLYALAFFLPSIIAGFREDFGLTLSIEQVGLITAIPYAFAAVAMYLWSRRADRTGAHTRHVAVPMLLGGLAIPVALY
LDSPVLVMIPVTLAAMGVFSAIPSFWALPSRFLTGAAAAGGIGLINSVGNLGGFAAPYVTGALDDALGSARAGMWAVGLM
MVISAGVVFTLSNDRLSPSTPATPPARR

Sequences:

>Translated_428_residues
MWRTVPILMALYFVNYLDRTNLGIARADISAHLQLSATMFGFASGIFFIGYVLVEVPSNLALHRFGARRWLARIAVSWGL
VVVAIGFAPNAPTLLALRFLLGVAEAGLFPGVILYLSRWFPTAYRARVVAMFMLASPIAAAVGTPVGAWLIDVGDGLFGL
AGWQFMMICSGLPAIALGVVCWIALTDRPADANWLPDDEKRWLIGVLAAEEHAVSSRFDFPLRRALRSPRVWALAVVYFG
VAYGLYALAFFLPSIIAGFREDFGLTLSIEQVGLITAIPYAFAAVAMYLWSRRADRTGAHTRHVAVPMLLGGLAIPVALY
LDSPVLVMIPVTLAAMGVFSAIPSFWALPSRFLTGAAAAGGIGLINSVGNLGGFAAPYVTGALDDALGSARAGMWAVGLM
MVISAGVVFTLSNDRLSPSTPATPPARR
>Mature_428_residues
MWRTVPILMALYFVNYLDRTNLGIARADISAHLQLSATMFGFASGIFFIGYVLVEVPSNLALHRFGARRWLARIAVSWGL
VVVAIGFAPNAPTLLALRFLLGVAEAGLFPGVILYLSRWFPTAYRARVVAMFMLASPIAAAVGTPVGAWLIDVGDGLFGL
AGWQFMMICSGLPAIALGVVCWIALTDRPADANWLPDDEKRWLIGVLAAEEHAVSSRFDFPLRRALRSPRVWALAVVYFG
VAYGLYALAFFLPSIIAGFREDFGLTLSIEQVGLITAIPYAFAAVAMYLWSRRADRTGAHTRHVAVPMLLGGLAIPVALY
LDSPVLVMIPVTLAAMGVFSAIPSFWALPSRFLTGAAAAGGIGLINSVGNLGGFAAPYVTGALDDALGSARAGMWAVGLM
MVISAGVVFTLSNDRLSPSTPATPPARR

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI21322234, Length=395, Percent_Identity=24.0506329113924, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI9945322, Length=401, Percent_Identity=22.4438902743142, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082071, Length=420, Percent_Identity=35.4761904761905, Blast_Score=252, Evalue=4e-68,
Organism=Escherichia coli, GI1789515, Length=410, Percent_Identity=27.3170731707317, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI2367379, Length=414, Percent_Identity=25.8454106280193, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082320, Length=403, Percent_Identity=25.3101736972705, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1789152, Length=436, Percent_Identity=22.7064220183486, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI2367193, Length=238, Percent_Identity=23.9495798319328, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=274, Percent_Identity=24.0875912408759, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6321698, Length=352, Percent_Identity=26.1363636363636, Blast_Score=86, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6322025, Length=180, Percent_Identity=26.1111111111111, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322612, Length=238, Percent_Identity=20.5882352941176, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24654215, Length=385, Percent_Identity=21.5584415584416, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19922400, Length=385, Percent_Identity=21.5584415584416, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24639764, Length=433, Percent_Identity=23.3256351039261, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641682, Length=429, Percent_Identity=23.7762237762238, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583789, Length=396, Percent_Identity=21.7171717171717, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45749; Mature: 45749

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRTVPILMALYFVNYLDRTNLGIARADISAHLQLSATMFGFASGIFFIGYVLVEVPSNL
CCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCH
ALHRFGARRWLARIAVSWGLVVVAIGFAPNAPTLLALRFLLGVAEAGLFPGVILYLSRWF
HHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
PTAYRARVVAMFMLASPIAAAVGTPVGAWLIDVGDGLFGLAGWQFMMICSGLPAIALGVV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHH
CWIALTDRPADANWLPDDEKRWLIGVLAAEEHAVSSRFDFPLRRALRSPRVWALAVVYFG
HHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHH
VAYGLYALAFFLPSIIAGFREDFGLTLSIEQVGLITAIPYAFAAVAMYLWSRRADRTGAH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TRHVAVPMLLGGLAIPVALYLDSPVLVMIPVTLAAMGVFSAIPSFWALPSRFLTGAAAAG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIGLINSVGNLGGFAAPYVTGALDDALGSARAGMWAVGLMMVISAGVVFTLSNDRLSPST
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
PATPPARR
CCCCCCCC
>Mature Secondary Structure
MWRTVPILMALYFVNYLDRTNLGIARADISAHLQLSATMFGFASGIFFIGYVLVEVPSNL
CCCHHHHHHHHHHHHHHCCCCCCEEEECHHHHEEHHHHHHHHHHHHHHHHHHHHHCCCCH
ALHRFGARRWLARIAVSWGLVVVAIGFAPNAPTLLALRFLLGVAEAGLFPGVILYLSRWF
HHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHC
PTAYRARVVAMFMLASPIAAAVGTPVGAWLIDVGDGLFGLAGWQFMMICSGLPAIALGVV
CHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCHHHHHHHHHHHHHCCCHHHHHHHH
CWIALTDRPADANWLPDDEKRWLIGVLAAEEHAVSSRFDFPLRRALRSPRVWALAVVYFG
HHHHCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHH
VAYGLYALAFFLPSIIAGFREDFGLTLSIEQVGLITAIPYAFAAVAMYLWSRRADRTGAH
HHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TRHVAVPMLLGGLAIPVALYLDSPVLVMIPVTLAAMGVFSAIPSFWALPSRFLTGAAAAG
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GIGLINSVGNLGGFAAPYVTGALDDALGSARAGMWAVGLMMVISAGVVFTLSNDRLSPST
CHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCC
PATPPARR
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]