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The map label for this gene is pbuG [H]

Identifier: 108797333

GI number: 108797333

Start: 394250

End: 395665

Strand: Reverse

Name: pbuG [H]

Synonym: Mmcs_0353

Alternate gene names: 108797333

Gene position: 395665-394250 (Counterclockwise)

Preceding gene: 108797335

Following gene: 108797328

Centisome position: 6.93

GC content: 67.73

Gene sequence:

>1416_bases
ATGAATCGCCTCGATCGCTTCTTCGAGATCTCCGCTCGTGGGTCGACGCTCGGCGCCGAGGTCCGCGGCGGCCTGGTCAC
GTTCATCGCGATGGCCTACATCATCGTGCTGAACCCGATCATCCTGTCGAGTTCCGACGACGTGGAGGGCAACTCGCTGC
AGTTCGCCCAGGTCTCGGCGACCACGGCGCTCGCCGCGGGGGTCATGACGATCCTGTTCGGTCTGATCGCACGGTTGCCC
TTCGCCTTCGCCGCCGGCCTGGGCATCAACTCGTTCCTGGCGACGACGGTGGTCGGTGACGTCACCTGGCCCGAGGCGAT
GGGCCTGGTGGTCATCAACGGTCTGATCATCGTGCTGCTGGCGGTGACCGGTCTGCGGCGACTGGTGTTCGACGCGGTGC
CGATGCAACTGAAGCTGGCCATCACCGCGGGCATCGGATTGTTCATCCTGTTCATCGGCCTCGTCGACGCCGGTTTCGTC
AACTCCACCGGGCTGGCGTCGCCGCCGGTCGGGCTGGGTGCCGGTGGACTGGGCTCGATCAACACCGTGCCGACGCTCAT
CTTCGTGATCACGCTGCTGGTCACCGGTGTGCTGGTCGCGCGGCGGGTGCGCGGCGGCATCCTGATCGGCCTGGTGGCCG
GAACCGTCATCGCCGTCGTCGTCGAGGCGATCTGGGATCTGGGATCGGCCCAGGACAAGGCCGGCGGCTGGAGCCTGTCG
GTGCCGCAGTTGTCCGGTTCGCCGTTCGCGCTACCGGACCTCTCGCTGGTCGGTGAGTTCAGCCTGACCGGTGCCTTCGA
GCGCATCGGGATCCTCGCGGCGGTGATGCTCGTCTTCACGCTGGTGTTCGCCAACTTCTTCGACGCGATGGGCACGTTCA
CCGGGCTCTCGCGCGAGGCGGGGCTCTCCGATGACCGGGGGACGTTCCCCCGGTTGCGCTCCGCGCTGATCGTCGAGGGT
GCGGGCGCGGCAGTCGGCGGTGCGTCGTCGGCGTCGTCCAACACGGTGTTCATCGAATCCGGCGCCGGTATCGAAGAGGG
CGCCCGCACCGGCCTGGCGAACCTGATCACCGGTGCGCTCTTCCTCGCCGCGATGTTCGTCTCCCCGCTGGCCTCCATCG
TGCCGACGGAGGTGGCCGCGGCCGCCCTGGTGGTCGTCGGCGCGATGATGGTGTCCCACCTGCGCCACATCGAACTGTCG
GAGTTCTCAGTGGCGCTGCCGGTCGTCCTCACCGTCGCCGCCATGCCGTTCACCTACTCCATCGCCAACGGAATCGGTGT
CGGGTTCATCTCGTGGGTGGTCGTCCGCTCCGGCGCCGGGAAGGCCCGCGAGATCAGCCCGCTGCTGTGGGTCGTGGCCG
CCGGCTTCCTCTTCTACTTCGCCCGCAGCTGGATCGAGACCCTCATGGGAGTGTGA

Upstream 100 bases:

>100_bases
CGCGTCCGCGAATGGGCTGTGGCCACCGAACCAATCTAGGATTCCTGGCGCCCGCCGTGGTAATTCGCCGTCGACGGTGG
TTCACCTTAGGGTTCGTCCC

Downstream 100 bases:

>100_bases
CCGGCTCGGCCTGAACGTCACCGCGACATGCTGAAAACCCTTGACCCGCTCGGCCTTCGCCTTGCGCGTGTAGGTGCGCC
GATCGGCGGAGGTCAGCGTC

Product: xanthine/uracil/vitamin C permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MNRLDRFFEISARGSTLGAEVRGGLVTFIAMAYIIVLNPIILSSSDDVEGNSLQFAQVSATTALAAGVMTILFGLIARLP
FAFAAGLGINSFLATTVVGDVTWPEAMGLVVINGLIIVLLAVTGLRRLVFDAVPMQLKLAITAGIGLFILFIGLVDAGFV
NSTGLASPPVGLGAGGLGSINTVPTLIFVITLLVTGVLVARRVRGGILIGLVAGTVIAVVVEAIWDLGSAQDKAGGWSLS
VPQLSGSPFALPDLSLVGEFSLTGAFERIGILAAVMLVFTLVFANFFDAMGTFTGLSREAGLSDDRGTFPRLRSALIVEG
AGAAVGGASSASSNTVFIESGAGIEEGARTGLANLITGALFLAAMFVSPLASIVPTEVAAAALVVVGAMMVSHLRHIELS
EFSVALPVVLTVAAMPFTYSIANGIGVGFISWVVVRSGAGKAREISPLLWVVAAGFLFYFARSWIETLMGV

Sequences:

>Translated_471_residues
MNRLDRFFEISARGSTLGAEVRGGLVTFIAMAYIIVLNPIILSSSDDVEGNSLQFAQVSATTALAAGVMTILFGLIARLP
FAFAAGLGINSFLATTVVGDVTWPEAMGLVVINGLIIVLLAVTGLRRLVFDAVPMQLKLAITAGIGLFILFIGLVDAGFV
NSTGLASPPVGLGAGGLGSINTVPTLIFVITLLVTGVLVARRVRGGILIGLVAGTVIAVVVEAIWDLGSAQDKAGGWSLS
VPQLSGSPFALPDLSLVGEFSLTGAFERIGILAAVMLVFTLVFANFFDAMGTFTGLSREAGLSDDRGTFPRLRSALIVEG
AGAAVGGASSASSNTVFIESGAGIEEGARTGLANLITGALFLAAMFVSPLASIVPTEVAAAALVVVGAMMVSHLRHIELS
EFSVALPVVLTVAAMPFTYSIANGIGVGFISWVVVRSGAGKAREISPLLWVVAAGFLFYFARSWIETLMGV
>Mature_471_residues
MNRLDRFFEISARGSTLGAEVRGGLVTFIAMAYIIVLNPIILSSSDDVEGNSLQFAQVSATTALAAGVMTILFGLIARLP
FAFAAGLGINSFLATTVVGDVTWPEAMGLVVINGLIIVLLAVTGLRRLVFDAVPMQLKLAITAGIGLFILFIGLVDAGFV
NSTGLASPPVGLGAGGLGSINTVPTLIFVITLLVTGVLVARRVRGGILIGLVAGTVIAVVVEAIWDLGSAQDKAGGWSLS
VPQLSGSPFALPDLSLVGEFSLTGAFERIGILAAVMLVFTLVFANFFDAMGTFTGLSREAGLSDDRGTFPRLRSALIVEG
AGAAVGGASSASSNTVFIESGAGIEEGARTGLANLITGALFLAAMFVSPLASIVPTEVAAAALVVVGAMMVSHLRHIELS
EFSVALPVVLTVAAMPFTYSIANGIGVGFISWVVVRSGAGKAREISPLLWVVAAGFLFYFARSWIETLMGV

Specific function: Involved in the uptake of the purine bases hypoxanthine and guanine [H]

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790150, Length=457, Percent_Identity=33.2603938730853, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI87082309, Length=460, Percent_Identity=32.1739130434783, Blast_Score=220, Evalue=1e-58,
Organism=Escherichia coli, GI1790499, Length=467, Percent_Identity=30.8351177730193, Blast_Score=172, Evalue=4e-44,
Organism=Escherichia coli, GI48994909, Length=465, Percent_Identity=30.752688172043, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 48454; Mature: 48454

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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HHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969499; 9384377; 11591660 [H]