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The map label for this gene is fadE [H]

Identifier: 108797222

GI number: 108797222

Start: 268985

End: 270820

Strand: Reverse

Name: fadE [H]

Synonym: Mmcs_0242

Alternate gene names: 108797222

Gene position: 270820-268985 (Counterclockwise)

Preceding gene: 108797224

Following gene: 108797220

Centisome position: 4.75

GC content: 66.99

Gene sequence:

>1836_bases
GTGAGCCACTACAAGAGCAACGTACGCGACCAGGTGTTCAACCTGTTCGAGGTACTCGGCGTCGACAAGGCCATGGGCCA
GGGCGACTTCAGCGAGCTGGACGCCGACACCGCCCGCGAGATGCTCGACGAGATGGCCCGGCTGGCGGAGGGCCCGATCG
CCGAGTCCTTCTTCGAGGGCGACCGCAATCCGCCGGTGTTCGATCCGAAGACCCACTCGGTGAAGCTGCCGGAGCCGTTC
AAGAAGTCCATGCGCGCCCTGTTCGACGCGGGCTGGGACAAGGCCGGCATGCCCGAGGAACTCGGCGGCATGCCGATGCC
CCGCGCGCTGCAGTGGGCCCTGATCGAGCACGTCCTCGGCGCCAACCCCGCCGCGTACATGTACGCCATGGGCGGCGGTA
TGGCCCACATCCTGCACAACCTCGGCACCGAGGAGCAGAAGAAGTGGGCGGTGCTCGCCGCTGAGCGCGGCTGGGGCGCC
ACCATGGTGCTGACCGAGCCCGATGCCGGCTCCGACGTCGGCGCCGGCCGCACCAAGGCCGTCAAGCAGGACGACGGCTC
CTGGCACATCGAGGGCGTCAAGCGGTTCATCACCTCGGCCGATTCCGACGACCTGTTCGAGAACATCTTCCACCTGGTGC
TGGCCCGCCCCGAGGGCGCAGGCCCGGGCACCAAGGGTCTGTCGCTGTTCTTCGTGCCGAAGTTCCTCGTGGACTTCGAG
ACCGGTGAGCTCGGCGAGCGCAACGGTGCCTTCGTCACCAACGTCGAGCACAAGATGGGCCTGAAGGTCTCGGCCACCTG
TGAGCTGTCCCTCGGACAGCACGGCGTGCCCGCCAAGGGCTGGCTGGTCGGCGAGGTGCACAACGGCATCGCGCAGATGT
TCGACGTCATCGAGCAGGCTCGAATGATGGTCGGCACCAAGGCCATCGCCACCCTGTCGACCGGTTACCTCAACGCGCTC
GAGTACGCCAAGAGCCGCGTGCAGGGTGCCGACATGACCCAGATGACCGACAAGACCGCGCCGCGCGTGACCATCACGCA
CCACCCCGACGTGCGTCGCTCGCTGATGACCCAGAAGGCCTACGCCGAGGGTCTTCGCGCGCTGTACCTCTACACCGCCA
CCTTCCAGGACACGGCGGTCGCCAAGGCCGTGCACGACGTGGACTCCGAGCTGGCGGTCCGCGTCAACGACCTGATGCTG
CCGATCGTCAAGGGTGTGGGTTCCGAGCAGGCGTACGCCAAGCTCACCGAGAGCCTGCAGACCTTCGGCGGTTCGGGCTT
CCTGCAGGACTACCCGATCGAGCAGTACATCCGCGACGCCAAGATCGACTCGCTGTACGAGGGCACCACCGCGATCCAGG
CGCAGGACTTCTTCTTCCGCAAGATCGTGCGGGACAAGGGCCAGGCGCTGGCGTACGTCGCGGGGCAGATCGAGCAGTTC
GTCAAGAGCGAGTCGGGCAACGGCCGCCTCAAGGCCGAGCGTGCACTGCTGGCGACCGCGCTGGAGGACGTGCAGGCGAT
GGCTGCGTCGCTCACCGGCTACCTGATGGCGGCGCAGGAGAACCCGGCCGAGCTGTACAAGGTCGGCCTCGGGTCGGTGC
GCTTCCTGATGAGCGTTGGCGACCTGGTCATCGGTTGGCTGCTGCAGCAGCAGGCCGCCGTGGCCATCGGCGCGCTCGAC
GGCGGTGCGACCGGTGAGGACAAGGCCTTCTACGAGGGCAAGGTCGCGGTTGCGTCGTTCTTCGCGAAGAACTTCCTGCC
GCTGCTGACCAGCACCCGCCAGGTGGTCGAGCACCTCGACAACGAGATCATGGAGCTCGACGAAGCCGCGTTCTGA

Upstream 100 bases:

>100_bases
GCGTTGAAGTTACCGAGCGGTATAGTCGGGCGCAGTTACTGGTGGGTAACTTAGCCCCAAGTACCCAACCGCAGGTGGCA
TTTCTCATCGAGGAGGCAAC

Downstream 100 bases:

>100_bases
TCCCTTCCACGCAGAAGGCCCTCGCTACGGCGAGGGCCTTTTGTGTGGGCGGAGGGCGGTGAGCAGACACAGAATCGCGT
GAAACACGCGCGTGCAACGC

Product: acyl-CoA dehydrogenase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MSHYKSNVRDQVFNLFEVLGVDKAMGQGDFSELDADTAREMLDEMARLAEGPIAESFFEGDRNPPVFDPKTHSVKLPEPF
KKSMRALFDAGWDKAGMPEELGGMPMPRALQWALIEHVLGANPAAYMYAMGGGMAHILHNLGTEEQKKWAVLAAERGWGA
TMVLTEPDAGSDVGAGRTKAVKQDDGSWHIEGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLVDFE
TGELGERNGAFVTNVEHKMGLKVSATCELSLGQHGVPAKGWLVGEVHNGIAQMFDVIEQARMMVGTKAIATLSTGYLNAL
EYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDTAVAKAVHDVDSELAVRVNDLML
PIVKGVGSEQAYAKLTESLQTFGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGQALAYVAGQIEQF
VKSESGNGRLKAERALLATALEDVQAMAASLTGYLMAAQENPAELYKVGLGSVRFLMSVGDLVIGWLLQQQAAVAIGALD
GGATGEDKAFYEGKVAVASFFAKNFLPLLTSTRQVVEHLDNEIMELDEAAF

Sequences:

>Translated_611_residues
MSHYKSNVRDQVFNLFEVLGVDKAMGQGDFSELDADTAREMLDEMARLAEGPIAESFFEGDRNPPVFDPKTHSVKLPEPF
KKSMRALFDAGWDKAGMPEELGGMPMPRALQWALIEHVLGANPAAYMYAMGGGMAHILHNLGTEEQKKWAVLAAERGWGA
TMVLTEPDAGSDVGAGRTKAVKQDDGSWHIEGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLVDFE
TGELGERNGAFVTNVEHKMGLKVSATCELSLGQHGVPAKGWLVGEVHNGIAQMFDVIEQARMMVGTKAIATLSTGYLNAL
EYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDTAVAKAVHDVDSELAVRVNDLML
PIVKGVGSEQAYAKLTESLQTFGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGQALAYVAGQIEQF
VKSESGNGRLKAERALLATALEDVQAMAASLTGYLMAAQENPAELYKVGLGSVRFLMSVGDLVIGWLLQQQAAVAIGALD
GGATGEDKAFYEGKVAVASFFAKNFLPLLTSTRQVVEHLDNEIMELDEAAF
>Mature_610_residues
SHYKSNVRDQVFNLFEVLGVDKAMGQGDFSELDADTAREMLDEMARLAEGPIAESFFEGDRNPPVFDPKTHSVKLPEPFK
KSMRALFDAGWDKAGMPEELGGMPMPRALQWALIEHVLGANPAAYMYAMGGGMAHILHNLGTEEQKKWAVLAAERGWGAT
MVLTEPDAGSDVGAGRTKAVKQDDGSWHIEGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLVDFET
GELGERNGAFVTNVEHKMGLKVSATCELSLGQHGVPAKGWLVGEVHNGIAQMFDVIEQARMMVGTKAIATLSTGYLNALE
YAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKAYAEGLRALYLYTATFQDTAVAKAVHDVDSELAVRVNDLMLP
IVKGVGSEQAYAKLTESLQTFGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGQALAYVAGQIEQFV
KSESGNGRLKAERALLATALEDVQAMAASLTGYLMAAQENPAELYKVGLGSVRFLMSVGDLVIGWLLQQQAAVAIGALDG
GATGEDKAFYEGKVAVASFFAKNFLPLLTSTRQVVEHLDNEIMELDEAAF

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=426, Percent_Identity=26.7605633802817, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI4501857, Length=434, Percent_Identity=26.036866359447, Blast_Score=90, Evalue=8e-18,
Organism=Homo sapiens, GI4557231, Length=392, Percent_Identity=26.0204081632653, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187960098, Length=392, Percent_Identity=26.0204081632653, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4557233, Length=362, Percent_Identity=26.7955801104972, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI87082384, Length=305, Percent_Identity=27.5409836065574, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI87081958, Length=375, Percent_Identity=25.0666666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1786223, Length=383, Percent_Identity=25.8485639686684, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17534899, Length=361, Percent_Identity=30.4709141274238, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI86563383, Length=380, Percent_Identity=26.0526315789474, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=380, Percent_Identity=26.0526315789474, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17569725, Length=426, Percent_Identity=27.9342723004695, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17570075, Length=298, Percent_Identity=28.1879194630872, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=25.7372654155496, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24660351, Length=399, Percent_Identity=26.0651629072682, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363737, Length=376, Percent_Identity=26.5957446808511, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646207, Length=319, Percent_Identity=25.705329153605, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=26.3297872340426, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 66547; Mature: 66415

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHYKSNVRDQVFNLFEVLGVDKAMGQGDFSELDADTAREMLDEMARLAEGPIAESFFEG
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHCC
DRNPPVFDPKTHSVKLPEPFKKSMRALFDAGWDKAGMPEELGGMPMPRALQWALIEHVLG
CCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHC
ANPAAYMYAMGGGMAHILHNLGTEEQKKWAVLAAERGWGATMVLTEPDAGSDVGAGRTKA
CCCHHHHEECCCCHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCC
VKQDDGSWHIEGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLVDFE
CCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCC
TGELGERNGAFVTNVEHKMGLKVSATCELSLGQHGVPAKGWLVGEVHNGIAQMFDVIEQA
CCCCCCCCCCEEEECHHHHCCEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALEYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLYTATFQDTAVAKAVHDVDSELAVRVNDLMLPIVKGVGSEQAYAKLTESLQ
HHHHHHEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TFGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGQALAYVAGQIEQF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VKSESGNGRLKAERALLATALEDVQAMAASLTGYLMAAQENPAELYKVGLGSVRFLMSVG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHH
DLVIGWLLQQQAAVAIGALDGGATGEDKAFYEGKVAVASFFAKNFLPLLTSTRQVVEHLD
HHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEIMELDEAAF
HHHHHHHHCCC
>Mature Secondary Structure 
SHYKSNVRDQVFNLFEVLGVDKAMGQGDFSELDADTAREMLDEMARLAEGPIAESFFEG
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHCC
DRNPPVFDPKTHSVKLPEPFKKSMRALFDAGWDKAGMPEELGGMPMPRALQWALIEHVLG
CCCCCCCCCCCCCEECCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHC
ANPAAYMYAMGGGMAHILHNLGTEEQKKWAVLAAERGWGATMVLTEPDAGSDVGAGRTKA
CCCHHHHEECCCCHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCC
VKQDDGSWHIEGVKRFITSADSDDLFENIFHLVLARPEGAGPGTKGLSLFFVPKFLVDFE
CCCCCCCEEHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHCCC
TGELGERNGAFVTNVEHKMGLKVSATCELSLGQHGVPAKGWLVGEVHNGIAQMFDVIEQA
CCCCCCCCCCEEEECHHHHCCEEEEEEEEECCCCCCCCCCEEEHHHHHHHHHHHHHHHHH
RMMVGTKAIATLSTGYLNALEYAKSRVQGADMTQMTDKTAPRVTITHHPDVRRSLMTQKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHH
YAEGLRALYLYTATFQDTAVAKAVHDVDSELAVRVNDLMLPIVKGVGSEQAYAKLTESLQ
HHHHHHEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TFGGSGFLQDYPIEQYIRDAKIDSLYEGTTAIQAQDFFFRKIVRDKGQALAYVAGQIEQF
HCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
VKSESGNGRLKAERALLATALEDVQAMAASLTGYLMAAQENPAELYKVGLGSVRFLMSVG
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHH
DLVIGWLLQQQAAVAIGALDGGATGEDKAFYEGKVAVASFFAKNFLPLLTSTRQVVEHLD
HHHHHHHHHHHHHHEEECCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
NEIMELDEAAF
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]