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The map label for this gene is speA [H]

Identifier: 108797210

GI number: 108797210

Start: 255315

End: 256769

Strand: Reverse

Name: speA [H]

Synonym: Mmcs_0230

Alternate gene names: 108797210

Gene position: 256769-255315 (Counterclockwise)

Preceding gene: 108797211

Following gene: 108797208

Centisome position: 4.5

GC content: 72.23

Gene sequence:

>1455_bases
ATGGACTCTGACCGGCACACGCGCGCACCGCTGTTCGAGGCGCTGCGCCGGTTCGTCGAACGCGATCAGGCGCCGTTCTA
CAGTCCCGGCCACAAGGGCGGCCGCACGCTGGACCCGTGGTTCCGCGAACACATCGCCGCCGTCGACCTCAACAATCTCG
CGGACCTCGACACGCTGCACTGCCCCAGCGGGCCGATCCTCGAAGCCGAAGAACTGATCGCCGATGCGTGGGGCGCCAAG
GCGAGCTTCATCCTCGTGCAGGGGTCGACCGGCGGCAACATCGCGGTCGCGTTGTCGGCGCTGCGACCCGGCGATCCGGT
GCTGGTGCAGCGCAACGCCCACAAGTCGGTGCTGGCCGGTCTGGTCCAGTCCGGTGCGCGGCCGATCTGGCTGACGCCGC
AGTGGGATGCGGATTTCGGTGTCGCGCACGGCCTTCCGGTCGACCGCGTCGAGGCGGCTCTGACCGCCGAGACCGCGGCC
GCGCTGTGGATACTGCACCCCACCTACTTCGGGACGACCGCCGACATCGCCGCGCTCACCGCGGTGTGCCGCCGCCACGG
CATCCCGCTGCTCGCCGACGGCGCCCACTCCCCGCACTTCGCCTTCCACCCCGACCTGCCGGCCGCCGCCGAGACCGCAG
GGGCGGCGGCGACCGTGCAGTCGGTGCACAAGATCCTCTCCGGGCTCAGCCAGGCCGCGGTGCTGCACGTCGACACCGAT
CAGCTGGACGTGCCGACGGTGCGCCGCGCGCTGCAGCTGGTCCAGACCACCAGCCCGCATTTCGCGATCATGGCGTCGAT
CGATCTGGCCCGCCGCCAGATGGTGGAGGACGGCCGCCGCCTCCTCGACGAGACGCTGCGGCGCGCCCGCGACACCGCTG
CGCGGCTGGCCCAGATCCCGGGACTACGCGTGCTGAGCGACCACGACCTCACCGGTCCGGGGTCCGGACTCCACCAGCGC
GACGAGACCAAACTGCTGATCGGGACGCACGGACTGGCCGCCGACGCATCCGACATCCTGGCGCGGCTGACCCGGGAACA
CGGCGTGCAGCCCGAACTCGCCGGCGCCGGCCACATCCTGTGCATCACCACGATCGGCAACACCGACGCCGACATGGACC
GGCTGGTCGACGGCCTGACCGATGTCGCCCTGGCGGTGGGCCGGCGCGACGGCGGGTGCCCGCCCGATGTGGGCGGTGCG
CTCGACCTGGCCCCGGAGATCGTGCTGACCCCGCGCGAGGCCTTCTTCGCCGACGTGGACACGGTTTCCCTGCGCGCGGC
GGTCGGCCGCATCGCCGCCGAACCGATCACGCCCTACCCGCCGGGCATTCCGCTGGTGATGCCCGGCGAACGCCTCAGCG
CCGAGGTCGTCGACGTACTCGACGGCCTGCGCGGTGCGGGCAACCCGATCAGCGCGGCGGACCCCACCCTCGAGCGGGTG
ACCGTCGTCCGGTGA

Upstream 100 bases:

>100_bases
GGCCTGGTGCTCGGCGACTGGGTCCGCACCGGCGACTGCACCGAGGCCGACGCGATCCGCATCGTCGACATGATCGGTGT
GCACAACGCCGAACGCGTCT

Downstream 100 bases:

>100_bases
GGTTCGGTCAGCCGCCGCAGCGCGGGTTCGGGCCCTTCATCGCCGCCACCCGCAGCACCGACTGGTCGACGCGCGGCATC
GTCAGCTCACCGGAGCCCAC

Product: Orn/Lys/Arg decarboxylase, major region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 484; Mature: 484

Protein sequence:

>484_residues
MDSDRHTRAPLFEALRRFVERDQAPFYSPGHKGGRTLDPWFREHIAAVDLNNLADLDTLHCPSGPILEAEELIADAWGAK
ASFILVQGSTGGNIAVALSALRPGDPVLVQRNAHKSVLAGLVQSGARPIWLTPQWDADFGVAHGLPVDRVEAALTAETAA
ALWILHPTYFGTTADIAALTAVCRRHGIPLLADGAHSPHFAFHPDLPAAAETAGAAATVQSVHKILSGLSQAAVLHVDTD
QLDVPTVRRALQLVQTTSPHFAIMASIDLARRQMVEDGRRLLDETLRRARDTAARLAQIPGLRVLSDHDLTGPGSGLHQR
DETKLLIGTHGLAADASDILARLTREHGVQPELAGAGHILCITTIGNTDADMDRLVDGLTDVALAVGRRDGGCPPDVGGA
LDLAPEIVLTPREAFFADVDTVSLRAAVGRIAAEPITPYPPGIPLVMPGERLSAEVVDVLDGLRGAGNPISAADPTLERV
TVVR

Sequences:

>Translated_484_residues
MDSDRHTRAPLFEALRRFVERDQAPFYSPGHKGGRTLDPWFREHIAAVDLNNLADLDTLHCPSGPILEAEELIADAWGAK
ASFILVQGSTGGNIAVALSALRPGDPVLVQRNAHKSVLAGLVQSGARPIWLTPQWDADFGVAHGLPVDRVEAALTAETAA
ALWILHPTYFGTTADIAALTAVCRRHGIPLLADGAHSPHFAFHPDLPAAAETAGAAATVQSVHKILSGLSQAAVLHVDTD
QLDVPTVRRALQLVQTTSPHFAIMASIDLARRQMVEDGRRLLDETLRRARDTAARLAQIPGLRVLSDHDLTGPGSGLHQR
DETKLLIGTHGLAADASDILARLTREHGVQPELAGAGHILCITTIGNTDADMDRLVDGLTDVALAVGRRDGGCPPDVGGA
LDLAPEIVLTPREAFFADVDTVSLRAAVGRIAAEPITPYPPGIPLVMPGERLSAEVVDVLDGLRGAGNPISAADPTLERV
TVVR
>Mature_484_residues
MDSDRHTRAPLFEALRRFVERDQAPFYSPGHKGGRTLDPWFREHIAAVDLNNLADLDTLHCPSGPILEAEELIADAWGAK
ASFILVQGSTGGNIAVALSALRPGDPVLVQRNAHKSVLAGLVQSGARPIWLTPQWDADFGVAHGLPVDRVEAALTAETAA
ALWILHPTYFGTTADIAALTAVCRRHGIPLLADGAHSPHFAFHPDLPAAAETAGAAATVQSVHKILSGLSQAAVLHVDTD
QLDVPTVRRALQLVQTTSPHFAIMASIDLARRQMVEDGRRLLDETLRRARDTAARLAQIPGLRVLSDHDLTGPGSGLHQR
DETKLLIGTHGLAADASDILARLTREHGVQPELAGAGHILCITTIGNTDADMDRLVDGLTDVALAVGRRDGGCPPDVGGA
LDLAPEIVLTPREAFFADVDTVSLRAAVGRIAAEPITPYPPGIPLVMPGERLSAEVVDVLDGLRGAGNPISAADPTLERV
TVVR

Specific function: Catalyzes the formation of agmatine from arginine [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786384, Length=552, Percent_Identity=26.9927536231884, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1790573, Length=552, Percent_Identity=26.4492753623188, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI221142684, Length=325, Percent_Identity=25.5384615384615, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 51294; Mature: 51294

Theoretical pI: Translated: 5.64; Mature: 5.64

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSDRHTRAPLFEALRRFVERDQAPFYSPGHKGGRTLDPWFREHIAAVDLNNLADLDTLH
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
CPSGPILEAEELIADAWGAKASFILVQGSTGGNIAVALSALRPGDPVLVQRNAHKSVLAG
CCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEECCCHHHHHHH
LVQSGARPIWLTPQWDADFGVAHGLPVDRVEAALTAETAAALWILHPTYFGTTADIAALT
HHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHH
AVCRRHGIPLLADGAHSPHFAFHPDLPAAAETAGAAATVQSVHKILSGLSQAAVLHVDTD
HHHHHCCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEEEECCC
QLDVPTVRRALQLVQTTSPHFAIMASIDLARRQMVEDGRRLLDETLRRARDTAARLAQIP
CCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLRVLSDHDLTGPGSGLHQRDETKLLIGTHGLAADASDILARLTREHGVQPELAGAGHIL
CCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
CITTIGNTDADMDRLVDGLTDVALAVGRRDGGCPPDVGGALDLAPEIVLTPREAFFADVD
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCEEECCHHHHHHCCC
TVSLRAAVGRIAAEPITPYPPGIPLVMPGERLSAEVVDVLDGLRGAGNPISAADPTLERV
HHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHE
TVVR
EECC
>Mature Secondary Structure
MDSDRHTRAPLFEALRRFVERDQAPFYSPGHKGGRTLDPWFREHIAAVDLNNLADLDTLH
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCC
CPSGPILEAEELIADAWGAKASFILVQGSTGGNIAVALSALRPGDPVLVQRNAHKSVLAG
CCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEECCCHHHHHHH
LVQSGARPIWLTPQWDADFGVAHGLPVDRVEAALTAETAAALWILHPTYFGTTADIAALT
HHHCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHH
AVCRRHGIPLLADGAHSPHFAFHPDLPAAAETAGAAATVQSVHKILSGLSQAAVLHVDTD
HHHHHCCCCEEECCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHEEEEEECCC
QLDVPTVRRALQLVQTTSPHFAIMASIDLARRQMVEDGRRLLDETLRRARDTAARLAQIP
CCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLRVLSDHDLTGPGSGLHQRDETKLLIGTHGLAADASDILARLTREHGVQPELAGAGHIL
CCEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
CITTIGNTDADMDRLVDGLTDVALAVGRRDGGCPPDVGGALDLAPEIVLTPREAFFADVD
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCCEEECCHHHHHHCCC
TVSLRAAVGRIAAEPITPYPPGIPLVMPGERLSAEVVDVLDGLRGAGNPISAADPTLERV
HHHHHHHHHHHHCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHE
TVVR
EECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377; 1697575; 1936936 [H]