Click here to switch to the map view.

The map label for this gene is ubiE [C]

Identifier: 108797198

GI number: 108797198

Start: 238825

End: 239583

Strand: Reverse

Name: ubiE [C]

Synonym: Mmcs_0218

Alternate gene names: 108797198

Gene position: 239583-238825 (Counterclockwise)

Preceding gene: 108797200

Following gene: 108797197

Centisome position: 4.2

GC content: 71.28

Gene sequence:

>759_bases
GTGTCCGCTACCGAGCTGTTCGCCCGACGCGCGACGCTGGCGCGATCGGTCCGGTTGCTCAGTGAGTTCCGCTTCGAGCA
GTCCGACCCGGCCCGCTTCTACGGCGCGCTCGCCGACGACACCGCCGCGATGGTGGCCGACCTGTGGCAGGCCGCGACGG
AAACGACTCCGGGCGGCCGCACGGTGCTCGACGTCGGCGGGGGGCCCGGATTCTTCGCCGCCGCGTTCACCCGTCGCGGC
ATGGAGTATGTGGGCGTCGAGCCCGACCCCCGCGAGATGCATGCCGGCCCCGCGGCACAGGTAGGCGGCCGCTACGTCCG
CGCCTCCGGTACATCGTTGCCATTCGCCGATGGCAGCGTCGACGTCTGCCTGTCCTCCAACGTCGCCGAGCACGTGCCGG
ATCCCTGGCGGCTGGGCAACGAGATGTTGCGCGTCACCCGGCCCGGTGGCCTCGCCGTGTTGTCCTACACCGTCTGGCTG
GGCCCGTTCGGCGGGCACGAGACGGGTCTGACGCACTACCTCGGCGGTGCCCGGGCCGCCGACCGATACACCCGCAAACA
CGGGCACCGGCCGAAGAACGACTACGGTTCGTCACTGTTCGCGGTATCGGCGCACGACGGCCTCGAGTGGGCGGCGAGCA
CCGGCGCCCTGATCGCCGCATTCCCCCGCTACCACCCGCGATGGGCGTGGTGGACCAACGCGGTACCGGGGCTCCGCGAG
TTCGTGGTGAGCAACCAGGTGCTGGTCCTGCAGCCCTGA

Upstream 100 bases:

>100_bases
CCTGGGGGTGACCGGTGTCCCGCCAGCACAAGAGCAGGACGGAACGAAGCGGGCGCGCGGACATCGTCGGCCAGCCTAAT
GGCTGCGTAGGGTCGGTCGC

Downstream 100 bases:

>100_bases
CTGCAACAGGTTCTCGTTTGCGCGTCCAATCGGTAGTGTGACCTCCATGACACAGACCGTGCAGGAGCACAAGACAACGT
GGGACAAGCTCTTCATCGGC

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MSATELFARRATLARSVRLLSEFRFEQSDPARFYGALADDTAAMVADLWQAATETTPGGRTVLDVGGGPGFFAAAFTRRG
MEYVGVEPDPREMHAGPAAQVGGRYVRASGTSLPFADGSVDVCLSSNVAEHVPDPWRLGNEMLRVTRPGGLAVLSYTVWL
GPFGGHETGLTHYLGGARAADRYTRKHGHRPKNDYGSSLFAVSAHDGLEWAASTGALIAAFPRYHPRWAWWTNAVPGLRE
FVVSNQVLVLQP

Sequences:

>Translated_252_residues
MSATELFARRATLARSVRLLSEFRFEQSDPARFYGALADDTAAMVADLWQAATETTPGGRTVLDVGGGPGFFAAAFTRRG
MEYVGVEPDPREMHAGPAAQVGGRYVRASGTSLPFADGSVDVCLSSNVAEHVPDPWRLGNEMLRVTRPGGLAVLSYTVWL
GPFGGHETGLTHYLGGARAADRYTRKHGHRPKNDYGSSLFAVSAHDGLEWAASTGALIAAFPRYHPRWAWWTNAVPGLRE
FVVSNQVLVLQP
>Mature_251_residues
SATELFARRATLARSVRLLSEFRFEQSDPARFYGALADDTAAMVADLWQAATETTPGGRTVLDVGGGPGFFAAAFTRRGM
EYVGVEPDPREMHAGPAAQVGGRYVRASGTSLPFADGSVDVCLSSNVAEHVPDPWRLGNEMLRVTRPGGLAVLSYTVWLG
PFGGHETGLTHYLGGARAADRYTRKHGHRPKNDYGSSLFAVSAHDGLEWAASTGALIAAFPRYHPRWAWWTNAVPGLREF
VVSNQVLVLQP

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27260; Mature: 27129

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATELFARRATLARSVRLLSEFRFEQSDPARFYGALADDTAAMVADLWQAATETTPGGR
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
TVLDVGGGPGFFAAAFTRRGMEYVGVEPDPREMHAGPAAQVGGRYVRASGTSLPFADGSV
EEEECCCCCHHHHHHHHHCCCEEECCCCCHHHHCCCCHHHHCCEEEEECCCCCCCCCCCE
DVCLSSNVAEHVPDPWRLGNEMLRVTRPGGLAVLSYTVWLGPFGGHETGLTHYLGGARAA
EEEECCCHHHHCCCHHHHCHHHEEEECCCCEEEEEEEEEECCCCCCCCCHHHHHCCCHHH
DRYTRKHGHRPKNDYGSSLFAVSAHDGLEWAASTGALIAAFPRYHPRWAWWTNAVPGLRE
HHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHCCCCEEEECCCCCCCCHHHCCCCHHHHH
FVVSNQVLVLQP
HHHCCCEEEECC
>Mature Secondary Structure 
SATELFARRATLARSVRLLSEFRFEQSDPARFYGALADDTAAMVADLWQAATETTPGGR
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
TVLDVGGGPGFFAAAFTRRGMEYVGVEPDPREMHAGPAAQVGGRYVRASGTSLPFADGSV
EEEECCCCCHHHHHHHHHCCCEEECCCCCHHHHCCCCHHHHCCEEEEECCCCCCCCCCCE
DVCLSSNVAEHVPDPWRLGNEMLRVTRPGGLAVLSYTVWLGPFGGHETGLTHYLGGARAA
EEEECCCHHHHCCCHHHHCHHHEEEECCCCEEEEEEEEEECCCCCCCCCHHHHHCCCHHH
DRYTRKHGHRPKNDYGSSLFAVSAHDGLEWAASTGALIAAFPRYHPRWAWWTNAVPGLRE
HHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHCCCCEEEECCCCCCCCHHHCCCCHHHHH
FVVSNQVLVLQP
HHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA