Click here to switch to the map view.

The map label for this gene is ygjG [C]

Identifier: 108797178

GI number: 108797178

Start: 216939

End: 218216

Strand: Reverse

Name: ygjG [C]

Synonym: Mmcs_0198

Alternate gene names: 108797178

Gene position: 218216-216939 (Counterclockwise)

Preceding gene: 108797180

Following gene: 108797177

Centisome position: 3.82

GC content: 65.73

Gene sequence:

>1278_bases
GTGTACGACTACGGCACGTTCTCGTTCGAGTCCAAGACTCAGGTGCTGGACCGGGCGAAGGCGTTCTGGAATCCGGACAA
GACGCAGTTCTGGACAGACGCCGGCGTAGACCTGGTGATCGACCGCAGGGAGGACTACTTCCTGTGGGACATGGGCGGTC
GCCGGCTCATCGACATGCACCTCAACGGCGGCACCTACAACCTCGGGCACCGCAACCCCGAAGTGATGCAAGCCGTTTCG
CAGGGCATGGAGATCTTCGACGTCGGCAACCACCACTTCCCGTCGGTGGCGCGCACCGCGCTGGCCCAACGCCTGGTGGA
GACCGCACCCGATTCGATCAGCAAGGTGGCCTTCGGCTCCGGCGGCGGGGAGGCGATCGACATCGCGCTCAAGAGCGCCC
GCCACGCCACCGGACGCCGCAAGATCGTGTCGATCATCAAGGCCTACCACGGCCACACCGGCCTGGCGGTCGCGACCGGA
GACGAGCGCTTCGCCAAACTGTTCCTCTCCGACCGGCCCGACGAGTTCATCCAGGTGCCGTTCGGCGACGTCGCCGCGAT
GGAACAGGCGCTCAAAGGCAACGATGTCGCGGCGGTCATCATGGAGACCATCCCCGCGACATACGGATTCCCGCTTCCCC
CACCGGGTTACCTCGAAGCGGTCTACGCCCTGACCCAGAAGTACGGCTCCCTCTACATCGCCGACGAGGTCCAGACCGGG
CTGATGCGCACCGGCGAACTGTGGGCGATCACCAAACACGGCATCGAACCGGACATCCTCGTCACCGGTAAGGGACTCTC
CGGCGGCGTGTACCCGATCACCGCGGCGCTGCTCGGTGACCGGGCCGCCCAGTGGCTCGACCAGGACGGCTTCGCCCACA
TCTCCACCTTCGGCGGCGCCGAACTGGGTTGTGTCGCAGCGATCAAGACCCTCGAGATCACCACCCGGCCCGAGGTGCGG
TCGATGGTGCACTACATCGCCGACATCTTCGACAACGGACTGCGCCGCATCCAGGACGACTATCCGGACTGGTTCATCGG
GATCCGGCAGAACGGGGTCGTGATCGGGCTGGAGTTCGACCACCCCGAGGGCGCCAAGTTCGTGATGCGCGAACTCTACG
AGAACGGCGTGTGGGCGATCTTCTCCACGCTCGATCCCCGTGTGCTGCAGTTCAAACCGGGTCTCCTGCTCGGCCGCGAC
CTGTGCGAGGACGTGCTGGACCGGCTGGAGGTCGCGGTGGGCCGGGCGAAGACTGCAGCCAGGAAGGGACGGGCATGA

Upstream 100 bases:

>100_bases
ACACCGGGACCGCTACGTATATTGGCACTACCAATAGGTCCCCGCAACAGGAACGGCGAACCATTGACATAAATGGTTGC
GACCTTTTACGGTGGGCCGC

Downstream 100 bases:

>100_bases
GCGACATCCCGGCAGGGCGAGCGGAGCGACGGGAGATTGCGGCAGCCGGCCACATGCTCGAGCGCGCCCGGTGGGCGGCA
CGGGCATATGCCGACTACGA

Product: aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MYDYGTFSFESKTQVLDRAKAFWNPDKTQFWTDAGVDLVIDRREDYFLWDMGGRRLIDMHLNGGTYNLGHRNPEVMQAVS
QGMEIFDVGNHHFPSVARTALAQRLVETAPDSISKVAFGSGGGEAIDIALKSARHATGRRKIVSIIKAYHGHTGLAVATG
DERFAKLFLSDRPDEFIQVPFGDVAAMEQALKGNDVAAVIMETIPATYGFPLPPPGYLEAVYALTQKYGSLYIADEVQTG
LMRTGELWAITKHGIEPDILVTGKGLSGGVYPITAALLGDRAAQWLDQDGFAHISTFGGAELGCVAAIKTLEITTRPEVR
SMVHYIADIFDNGLRRIQDDYPDWFIGIRQNGVVIGLEFDHPEGAKFVMRELYENGVWAIFSTLDPRVLQFKPGLLLGRD
LCEDVLDRLEVAVGRAKTAARKGRA

Sequences:

>Translated_425_residues
MYDYGTFSFESKTQVLDRAKAFWNPDKTQFWTDAGVDLVIDRREDYFLWDMGGRRLIDMHLNGGTYNLGHRNPEVMQAVS
QGMEIFDVGNHHFPSVARTALAQRLVETAPDSISKVAFGSGGGEAIDIALKSARHATGRRKIVSIIKAYHGHTGLAVATG
DERFAKLFLSDRPDEFIQVPFGDVAAMEQALKGNDVAAVIMETIPATYGFPLPPPGYLEAVYALTQKYGSLYIADEVQTG
LMRTGELWAITKHGIEPDILVTGKGLSGGVYPITAALLGDRAAQWLDQDGFAHISTFGGAELGCVAAIKTLEITTRPEVR
SMVHYIADIFDNGLRRIQDDYPDWFIGIRQNGVVIGLEFDHPEGAKFVMRELYENGVWAIFSTLDPRVLQFKPGLLLGRD
LCEDVLDRLEVAVGRAKTAARKGRA
>Mature_425_residues
MYDYGTFSFESKTQVLDRAKAFWNPDKTQFWTDAGVDLVIDRREDYFLWDMGGRRLIDMHLNGGTYNLGHRNPEVMQAVS
QGMEIFDVGNHHFPSVARTALAQRLVETAPDSISKVAFGSGGGEAIDIALKSARHATGRRKIVSIIKAYHGHTGLAVATG
DERFAKLFLSDRPDEFIQVPFGDVAAMEQALKGNDVAAVIMETIPATYGFPLPPPGYLEAVYALTQKYGSLYIADEVQTG
LMRTGELWAITKHGIEPDILVTGKGLSGGVYPITAALLGDRAAQWLDQDGFAHISTFGGAELGCVAAIKTLEITTRPEVR
SMVHYIADIFDNGLRRIQDDYPDWFIGIRQNGVVIGLEFDHPEGAKFVMRELYENGVWAIFSTLDPRVLQFKPGLLLGRD
LCEDVLDRLEVAVGRAKTAARKGRA

Specific function: Unknown

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI24119277, Length=418, Percent_Identity=26.7942583732057, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI4557809, Length=371, Percent_Identity=28.3018867924528, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI37574042, Length=435, Percent_Identity=25.0574712643678, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI226442709, Length=378, Percent_Identity=25.6613756613757, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI226442705, Length=435, Percent_Identity=24.5977011494253, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI284507298, Length=225, Percent_Identity=34.2222222222222, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI13994255, Length=390, Percent_Identity=22.3076923076923, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI145693181, Length=369, Percent_Identity=33.8753387533875, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1789759, Length=377, Percent_Identity=29.973474801061, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788044, Length=380, Percent_Identity=29.4736842105263, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI1787560, Length=338, Percent_Identity=28.4023668639053, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789016, Length=339, Percent_Identity=26.2536873156342, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1786991, Length=395, Percent_Identity=26.0759493670886, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786349, Length=262, Percent_Identity=27.8625954198473, Blast_Score=86, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=422, Percent_Identity=28.1990521327014, Blast_Score=145, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25144274, Length=232, Percent_Identity=34.4827586206897, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI32564660, Length=433, Percent_Identity=24.4803695150115, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=27.2058823529412, Blast_Score=111, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6323470, Length=343, Percent_Identity=26.530612244898, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6324386, Length=314, Percent_Identity=29.2993630573248, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=29.1777188328912, Blast_Score=144, Evalue=1e-34,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=26.2254901960784, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI161085790, Length=426, Percent_Identity=29.1079812206573, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI28574759, Length=364, Percent_Identity=29.9450549450549, Blast_Score=118, Evalue=9e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 46857; Mature: 46857

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDYGTFSFESKTQVLDRAKAFWNPDKTQFWTDAGVDLVIDRREDYFLWDMGGRRLIDMH
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCEEEEECCCCEEEEEE
LNGGTYNLGHRNPEVMQAVSQGMEIFDVGNHHFPSVARTALAQRLVETAPDSISKVAFGS
ECCCEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHEECC
GGGEAIDIALKSARHATGRRKIVSIIKAYHGHTGLAVATGDERFAKLFLSDRPDEFIQVP
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCEEECC
FGDVAAMEQALKGNDVAAVIMETIPATYGFPLPPPGYLEAVYALTQKYGSLYIADEVQTG
CCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHH
LMRTGELWAITKHGIEPDILVTGKGLSGGVYPITAALLGDRAAQWLDQDGFAHISTFGGA
HHCCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
ELGCVAAIKTLEITTRPEVRSMVHYIADIFDNGLRRIQDDYPDWFIGIRQNGVVIGLEFD
CHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECC
HPEGAKFVMRELYENGVWAIFSTLDPRVLQFKPGLLLGRDLCEDVLDRLEVAVGRAKTAA
CCCCHHHHHHHHHHCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKGRA
HCCCC
>Mature Secondary Structure
MYDYGTFSFESKTQVLDRAKAFWNPDKTQFWTDAGVDLVIDRREDYFLWDMGGRRLIDMH
CCCCCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEEEECCCCEEEEECCCCEEEEEE
LNGGTYNLGHRNPEVMQAVSQGMEIFDVGNHHFPSVARTALAQRLVETAPDSISKVAFGS
ECCCEEECCCCCHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHEECC
GGGEAIDIALKSARHATGRRKIVSIIKAYHGHTGLAVATGDERFAKLFLSDRPDEFIQVP
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHCCCCCCEEECC
FGDVAAMEQALKGNDVAAVIMETIPATYGFPLPPPGYLEAVYALTQKYGSLYIADEVQTG
CCHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEHHHHHH
LMRTGELWAITKHGIEPDILVTGKGLSGGVYPITAALLGDRAAQWLDQDGFAHISTFGGA
HHCCCCEEEEECCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
ELGCVAAIKTLEITTRPEVRSMVHYIADIFDNGLRRIQDDYPDWFIGIRQNGVVIGLEFD
CHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEECC
HPEGAKFVMRELYENGVWAIFSTLDPRVLQFKPGLLLGRDLCEDVLDRLEVAVGRAKTAA
CCCCHHHHHHHHHHCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RKGRA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]