BacMap

Definition	Mycobacterium sp. MCS chromosome, complete genome.
Accession	NC_008146
Length	5,705,448

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The map label for this gene is yqjQ [H]

Identifier: 108797168

GI number: 108797168

Start: 209526

End: 210314

Strand: Direct

Name: yqjQ [H]

Synonym: Mmcs_0188

Alternate gene names: 108797168

Gene position: 209526-210314 (Clockwise)

Preceding gene: 108797165

Following gene: 108797179

Centisome position: 3.67

GC content: 69.58

Gene sequence:

>789_bases
GTGAAGCTCACCGGATACACCGCGCTCGTCACCGGCGCCAGCGGCGGCATCGGCGAGGAGTTCGCCACGCGGTTGGCCGC
CGACCGGGTCAACCTGATCCTCGTCGCGCGGCGCACCGAGCGGCTCGAGGAGTTGCGCAGCAGGTTGCTCGATCGCCATC
CCGGGATCGACATCGACGTGCTGTCGGCCGATCTGGGGGTGCCGGGCGCGGCCGCCGCGCTCGCCCAGCAGGTCGACGCC
CTCGGCCGCCGGGTGGATGTGCTGATCAACAACGCCGGCATCGGTCTGCACGGCAGCTTCGCCGAACAGGACCCGGCGGC
CAACGCCGCGCAGATCCAGTTGAACTGCGTCACTCTGGTCGAGTTGACCGGCTGTTTCCTGCCGGCGATGATCGCCGCGA
AACGCGGGGTGGTCCTCAACGTCGGGTCGACCGCCGGTTTCCAGCCCGTGCCCAGCATGGCGGTGTACGGCGCCACCAAG
GCCTTCGTGCTGTCGTTCTCCGAGGCGCTGTGGCAGGAGACCCGCGGCTCGGGGGTCAAGGTGCTCACGCTGTGTCCGGG
CGCCACCGAGACCGAGTTCTTCGACCGCACCGGAAAGAGCTTCATGACGCGTGGCCGTCAGAGCTCGGCGCAGGTCGTCG
ACACCGCGCTCAAGGCACTCGACCGCCCGTTCCCGACGGTGGTGTCCGGTCTGCACAACCGCATCCTGGCGCTCGGCTAC
CGGATCGCGCCGCGGCCGGTGCTCGCGATGGTCTCCGAACAGCTGATGAAGGCGCGCGGTCAGGGTTAG

Upstream 100 bases:

>100_bases
CGCGAGCCGGAAACCTTCATCTGCCCGACGATACGACGGTCGGTGCGCTCCGGTGGTTACGTTGGACCAATGAAGGTCCA
ACGATCATGAGGTTCCGACA

Downstream 100 bases:

>100_bases
ACGGCGAGCTGGCTCTGCAGTTTGACCGACGCCGTGTTGGTGTCGGGTCCGCTGCCGAGCCCCTTGCCGATGCCCCTGCC
CTGTGCGGTGACGGCGAGGT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MKLTGYTALVTGASGGIGEEFATRLAADRVNLILVARRTERLEELRSRLLDRHPGIDIDVLSADLGVPGAAAALAQQVDA
LGRRVDVLINNAGIGLHGSFAEQDPAANAAQIQLNCVTLVELTGCFLPAMIAAKRGVVLNVGSTAGFQPVPSMAVYGATK
AFVLSFSEALWQETRGSGVKVLTLCPGATETEFFDRTGKSFMTRGRQSSAQVVDTALKALDRPFPTVVSGLHNRILALGY
RIAPRPVLAMVSEQLMKARGQG

Sequences:

>Translated_262_residues
MKLTGYTALVTGASGGIGEEFATRLAADRVNLILVARRTERLEELRSRLLDRHPGIDIDVLSADLGVPGAAAALAQQVDA
LGRRVDVLINNAGIGLHGSFAEQDPAANAAQIQLNCVTLVELTGCFLPAMIAAKRGVVLNVGSTAGFQPVPSMAVYGATK
AFVLSFSEALWQETRGSGVKVLTLCPGATETEFFDRTGKSFMTRGRQSSAQVVDTALKALDRPFPTVVSGLHNRILALGY
RIAPRPVLAMVSEQLMKARGQG
>Mature_262_residues
MKLTGYTALVTGASGGIGEEFATRLAADRVNLILVARRTERLEELRSRLLDRHPGIDIDVLSADLGVPGAAAALAQQVDA
LGRRVDVLINNAGIGLHGSFAEQDPAANAAQIQLNCVTLVELTGCFLPAMIAAKRGVVLNVGSTAGFQPVPSMAVYGATK
AFVLSFSEALWQETRGSGVKVLTLCPGATETEFFDRTGKSFMTRGRQSSAQVVDTALKALDRPFPTVVSGLHNRILALGY
RIAPRPVLAMVSEQLMKARGQG

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7706318, Length=200, Percent_Identity=34, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=28.2051282051282, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI4557649, Length=202, Percent_Identity=28.2178217821782, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI226371731, Length=195, Percent_Identity=27.1794871794872, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI20149619, Length=189, Percent_Identity=28.5714285714286, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI142976729, Length=202, Percent_Identity=29.7029702970297, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=27.8846153846154, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI223718074, Length=261, Percent_Identity=30.6513409961686, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI66933014, Length=151, Percent_Identity=28.476821192053, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=35.1351351351351, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082100, Length=225, Percent_Identity=32, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=29.5, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787335, Length=193, Percent_Identity=28.4974093264249, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788459, Length=192, Percent_Identity=28.125, Blast_Score=61, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25152911, Length=204, Percent_Identity=32.3529411764706, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17557668, Length=212, Percent_Identity=28.7735849056604, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI212646214, Length=203, Percent_Identity=27.5862068965517, Blast_Score=87, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559552, Length=203, Percent_Identity=28.0788177339901, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=213, Percent_Identity=30.9859154929577, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560176, Length=212, Percent_Identity=28.3018867924528, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17508895, Length=253, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=211, Percent_Identity=28.9099526066351, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562904, Length=205, Percent_Identity=27.3170731707317, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=203, Percent_Identity=30.0492610837438, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=203, Percent_Identity=29.064039408867, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560676, Length=192, Percent_Identity=27.0833333333333, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17532725, Length=248, Percent_Identity=23.7903225806452, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=206, Percent_Identity=30.0970873786408, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=201, Percent_Identity=28.3582089552239, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=203, Percent_Identity=29.064039408867, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=201, Percent_Identity=27.363184079602, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=209, Percent_Identity=28.2296650717703, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=201, Percent_Identity=27.8606965174129, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=195, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=233, Percent_Identity=26.6094420600858, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=200, Percent_Identity=28, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=197, Percent_Identity=30.9644670050761, Blast_Score=96, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6319635, Length=190, Percent_Identity=27.8947368421053, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640442, Length=193, Percent_Identity=33.6787564766839, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24584752, Length=186, Percent_Identity=32.258064516129, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24584744, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574402, Length=263, Percent_Identity=29.277566539924, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI161076933, Length=199, Percent_Identity=30.1507537688442, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24584748, Length=199, Percent_Identity=30.1507537688442, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=30.9278350515464, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI23397609, Length=198, Percent_Identity=34.3434343434343, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221331216, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24665247, Length=240, Percent_Identity=28.3333333333333, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI221331218, Length=240, Percent_Identity=28.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24665243, Length=240, Percent_Identity=28.3333333333333, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24580925, Length=272, Percent_Identity=27.9411764705882, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571526, Length=190, Percent_Identity=30.5263157894737, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI116007236, Length=241, Percent_Identity=29.4605809128631, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24648944, Length=227, Percent_Identity=29.5154185022026, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21357041, Length=192, Percent_Identity=30.2083333333333, Blast_Score=68, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24665264, Length=208, Percent_Identity=28.3653846153846, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355631, Length=175, Percent_Identity=30.8571428571429, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24644339, Length=219, Percent_Identity=26.9406392694064, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24641232, Length=227, Percent_Identity=28.1938325991189, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27714; Mature: 27714

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTGYTALVTGASGGIGEEFATRLAADRVNLILVARRTERLEELRSRLLDRHPGIDIDV
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEE
LSADLGVPGAAAALAQQVDALGRRVDVLINNAGIGLHGSFAEQDPAANAAQIQLNCVTLV
EECCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHH
ELTGCFLPAMIAAKRGVVLNVGSTAGFQPVPSMAVYGATKAFVLSFSEALWQETRGSGVK
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEE
VLTLCPGATETEFFDRTGKSFMTRGRQSSAQVVDTALKALDRPFPTVVSGLHNRILALGY
EEEECCCCCCHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
RIAPRPVLAMVSEQLMKARGQG
CCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLTGYTALVTGASGGIGEEFATRLAADRVNLILVARRTERLEELRSRLLDRHPGIDIDV
CCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCEEE
LSADLGVPGAAAALAQQVDALGRRVDVLINNAGIGLHGSFAEQDPAANAAQIQLNCVTLV
EECCCCCCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEHHHHH
ELTGCFLPAMIAAKRGVVLNVGSTAGFQPVPSMAVYGATKAFVLSFSEALWQETRGSGVK
HHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCEE
VLTLCPGATETEFFDRTGKSFMTRGRQSSAQVVDTALKALDRPFPTVVSGLHNRILALGY
EEEECCCCCCHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
RIAPRPVLAMVSEQLMKARGQG
CCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]