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The map label for this gene is scoA [H]

Identifier: 108764087

GI number: 108764087

Start: 4555059

End: 4555757

Strand: Reverse

Name: scoA [H]

Synonym: MXAN_3790

Alternate gene names: 108764087

Gene position: 4555757-4555059 (Counterclockwise)

Preceding gene: 108757905

Following gene: 108756835

Centisome position: 49.85

GC content: 64.95

Gene sequence:

>699_bases
ATGAACAAGGTCTACGCGAACGCGGACGAGGCGGTCGCCGACATCCCGGATGGCTGCACGCTCATGAGCGGCGGCTTCGG
GCTGTGCGGCAACCCGGAGAATCTCATCGAGGCACTTCACCGGAAGAACGTGAAGGACCTCACCATCATCTCCAACAACT
GCGGCACCACCGAGCTGGGGCTCGGAATCCTGCTTCAGAACAAGCAGGTGAAGAAGATGGTGTCCAGCTACGTGGGAGAG
AACAAGGAGTTCGAGCGACAGTTCCTCTCCGGTGAGCTGGAGGTGGAGCTGAACCCGCAGGGCACCCTGGCCGAGCGCAT
CCGCGCGGGCGGCTGCGGCATTGGCGGCTTCTTCACCCCGACGGGCGCCGGCACCCAGGTGGCCGAAGGGAAGGAGACGC
GCGTCATCGACGGGCGGCTGCACGTGCTGGAGACGCCGCTGAAGGCGGACTTCGCCATTGTCCGTGCGTGGAAGGCGGAC
CGCTGGGGCAACCTGGTGTTCCGCAAGACGGCGCGGAACTTCTCTCCGATGATGTGCATGGCGGCCAAGGTCACCATCGT
CGAGGCGGAGCACATCGTGGAGCCGGGCGAGCTGGACCCGGACCTGGTGCACATCCCGAGCATCTTCGTGAAGCGCATCG
TCCAGGCGAAGAACCTCCAGAAGTGGATCGAGCGGCGCACCGTCCGCAAGTCGGCCTGA

Upstream 100 bases:

>100_bases
GCTGATGGTGGAGCGCTGAACTTCCTCTCCCAATAGGAGAGGGGCACGGGGTGGGGGCCTGCCAAGGGCCTTCACCCCGT
TCGCACATGCGGGAGGGCGG

Downstream 100 bases:

>100_bases
GGAGCCCAGCCATGCCACTGACTCGTGAACAGATTGCACAGCGCATCGCCCAGGAGCTGCAGGACGGCTTCTACGTCAAC
CTGGGTATCGGCATGCCCAC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKVYANADEAVADIPDGCTLMSGGFGLCGNPENLIEALHRKNVKDLTIISNNCGTTELGLGILLQNKQVKKMVSSYVGE
NKEFERQFLSGELEVELNPQGTLAERIRAGGCGIGGFFTPTGAGTQVAEGKETRVIDGRLHVLETPLKADFAIVRAWKAD
RWGNLVFRKTARNFSPMMCMAAKVTIVEAEHIVEPGELDPDLVHIPSIFVKRIVQAKNLQKWIERRTVRKSA

Sequences:

>Translated_232_residues
MNKVYANADEAVADIPDGCTLMSGGFGLCGNPENLIEALHRKNVKDLTIISNNCGTTELGLGILLQNKQVKKMVSSYVGE
NKEFERQFLSGELEVELNPQGTLAERIRAGGCGIGGFFTPTGAGTQVAEGKETRVIDGRLHVLETPLKADFAIVRAWKAD
RWGNLVFRKTARNFSPMMCMAAKVTIVEAEHIVEPGELDPDLVHIPSIFVKRIVQAKNLQKWIERRTVRKSA
>Mature_232_residues
MNKVYANADEAVADIPDGCTLMSGGFGLCGNPENLIEALHRKNVKDLTIISNNCGTTELGLGILLQNKQVKKMVSSYVGE
NKEFERQFLSGELEVELNPQGTLAERIRAGGCGIGGFFTPTGAGTQVAEGKETRVIDGRLHVLETPLKADFAIVRAWKAD
RWGNLVFRKTARNFSPMMCMAAKVTIVEAEHIVEPGELDPDLVHIPSIFVKRIVQAKNLQKWIERRTVRKSA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=55.0607287449393, Blast_Score=279, Evalue=2e-75,
Organism=Homo sapiens, GI11545841, Length=246, Percent_Identity=52.4390243902439, Blast_Score=244, Evalue=5e-65,
Organism=Escherichia coli, GI1788551, Length=201, Percent_Identity=46.7661691542289, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=54.320987654321, Blast_Score=263, Evalue=7e-71,
Organism=Drosophila melanogaster, GI21358325, Length=241, Percent_Identity=50.207468879668, Blast_Score=244, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24655794, Length=241, Percent_Identity=50.207468879668, Blast_Score=244, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25521; Mature: 25521

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYANADEAVADIPDGCTLMSGGFGLCGNPENLIEALHRKNVKDLTIISNNCGTTELG
CCCCCCCCCHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHC
LGILLQNKQVKKMVSSYVGENKEFERQFLSGELEVELNPQGTLAERIRAGGCGIGGFFTP
CEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCC
TGAGTQVAEGKETRVIDGRLHVLETPLKADFAIVRAWKADRWGNLVFRKTARNFSPMMCM
CCCCCCCCCCCCCEEECCEEEEEECCCHHHHHHEEECCCCCCCCCEEEHHHCCCCHHHHH
AAKVTIVEAEHIVEPGELDPDLVHIPSIFVKRIVQAKNLQKWIERRTVRKSA
HHEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKVYANADEAVADIPDGCTLMSGGFGLCGNPENLIEALHRKNVKDLTIISNNCGTTELG
CCCCCCCCCHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHC
LGILLQNKQVKKMVSSYVGENKEFERQFLSGELEVELNPQGTLAERIRAGGCGIGGFFTP
CEEEECCHHHHHHHHHHHCCCHHHHHHHHCCCEEEEECCCCHHHHHHHCCCCCCCCCCCC
TGAGTQVAEGKETRVIDGRLHVLETPLKADFAIVRAWKADRWGNLVFRKTARNFSPMMCM
CCCCCCCCCCCCCEEECCEEEEEECCCHHHHHHEEECCCCCCCCCEEEHHHCCCCHHHHH
AAKVTIVEAEHIVEPGELDPDLVHIPSIFVKRIVQAKNLQKWIERRTVRKSA
HHEEEEEEHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]