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The map label for this gene is guaD [H]

Identifier: 108763474

GI number: 108763474

Start: 6751913

End: 6752374

Strand: Reverse

Name: guaD [H]

Synonym: MXAN_5421

Alternate gene names: 108763474

Gene position: 6752374-6751913 (Counterclockwise)

Preceding gene: 108763804

Following gene: 108762447

Centisome position: 73.88

GC content: 66.02

Gene sequence:

>462_bases
ATGGAGAGGTCCGCCGAAGAATTCATGCGCGAGGCCATCGCCCTGGCTCGCACCAACGTCAAGTCCGGTGGCCGTCCGTT
CGGGGCCTTGCTCGTGCGCGACGGCCGGGTGATTGCGCGCGCGGTCAACGAGGTCAATCAGACGAAGGATCCCACCGCCC
ACGCCGAGCTTCTGGCCATTCGCAATGCGAGCCAGAGCCTCGGTAGCGCCAGCCTGAGCGGCTGCGTCGTCTATGCCAGT
GGTCATCCCTGCCCGATGTGTCTGGCCGCCATGTACCTGTGCGGAATCCAGGGCGCCTATTTCGCTTACTCCAACGAGGA
GGGTGAAGCCTTCGGCCTCTCCACCGCGCCGATCTACGCGCAGTTGGCCCGCGAGCCCCAAGCCCAGTCCCTCGCCTTGC
GGCCTCTGCGCCCGGCGGACGAGCACGGACTGTACGACGAGTGGAAGCGTCATCAGGGATGA

Upstream 100 bases:

>100_bases
TCAACCTGGCGGACGGAAACGGCGTTACGCCGCTCCAGCACGCCCGCGAGCGCAAGCAAGACGCGATTGCCAAGATGCTC
GTAGCCGCCGGAGGTCGCTG

Downstream 100 bases:

>100_bases
CCGATAAGGAGCTCCGGATGCGTCAGTCAGTCGACTCCTCCCGTACGTCCACCCCAGTCGAGCTGGTGAACGTAACCCTT
CCTGATGGCCGCTGCGTGGA

Product: putative guanine deaminase

Products: NA

Alternate protein names: GDEase; Guanase; Guanine aminase; Guanine aminohydrolase; GAH [H]

Number of amino acids: Translated: 153; Mature: 153

Protein sequence:

>153_residues
MERSAEEFMREAIALARTNVKSGGRPFGALLVRDGRVIARAVNEVNQTKDPTAHAELLAIRNASQSLGSASLSGCVVYAS
GHPCPMCLAAMYLCGIQGAYFAYSNEEGEAFGLSTAPIYAQLAREPQAQSLALRPLRPADEHGLYDEWKRHQG

Sequences:

>Translated_153_residues
MERSAEEFMREAIALARTNVKSGGRPFGALLVRDGRVIARAVNEVNQTKDPTAHAELLAIRNASQSLGSASLSGCVVYAS
GHPCPMCLAAMYLCGIQGAYFAYSNEEGEAFGLSTAPIYAQLAREPQAQSLALRPLRPADEHGLYDEWKRHQG
>Mature_153_residues
MERSAEEFMREAIALARTNVKSGGRPFGALLVRDGRVIARAVNEVNQTKDPTAHAELLAIRNASQSLGSASLSGCVVYAS
GHPCPMCLAAMYLCGIQGAYFAYSNEEGEAFGLSTAPIYAQLAREPQAQSLALRPLRPADEHGLYDEWKRHQG

Specific function: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=112, Percent_Identity=33.9285714285714, Blast_Score=63, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17554608, Length=125, Percent_Identity=37.6, Blast_Score=98, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17555996, Length=127, Percent_Identity=37.007874015748, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=109, Percent_Identity=35.7798165137615, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.3 [H]

Molecular weight: Translated: 16538; Mature: 16538

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERSAEEFMREAIALARTNVKSGGRPFGALLVRDGRVIARAVNEVNQTKDPTAHAELLAI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHH
RNASQSLGSASLSGCVVYASGHPCPMCLAAMYLCGIQGAYFAYSNEEGEAFGLSTAPIYA
HCCHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCHHHHH
QLAREPQAQSLALRPLRPADEHGLYDEWKRHQG
HHHCCCCCHHEECCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MERSAEEFMREAIALARTNVKSGGRPFGALLVRDGRVIARAVNEVNQTKDPTAHAELLAI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHH
RNASQSLGSASLSGCVVYASGHPCPMCLAAMYLCGIQGAYFAYSNEEGEAFGLSTAPIYA
HCCHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCCCCEECCCCHHHHH
QLAREPQAQSLALRPLRPADEHGLYDEWKRHQG
HHHCCCCCHHEECCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 11101664 [H]