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The map label for this gene is mhpA [H]

Identifier: 108763094

GI number: 108763094

Start: 4115407

End: 4117032

Strand: Direct

Name: mhpA [H]

Synonym: MXAN_3533

Alternate gene names: 108763094

Gene position: 4115407-4117032 (Clockwise)

Preceding gene: 108763899

Following gene: 108759727

Centisome position: 45.03

GC content: 70.42

Gene sequence:

>1626_bases
ATGGCTCCGGAGTCCGTTGATGTCATCATCGTGGGCAGTGGTCCGGTGGGAGCGATGGCGGCGAATCTCCTGGGACAGCA
GGGGATTCGGACGCTGGTGGTGGAGCGTGAAGTCACGCCTCATGGCCAGTCCCGCGCCATCAGCGTGGATGACGAGGGCC
AGCGCATCTTCCAGTCCGCGGGGCTGGTGGGCGACCTGGGCGCGGGCTTCTATCCGTGCAAGCGGCTGCAGTACCTGAAT
GACTCGCTGCGCTCGCTGGCGGAGGTGGACTTCACCCGGTTGGACCGGCCGTTCGGCTACGTGCCCGCGGCCTTCTTCCA
GCAGCCGCGCATGGAGGCGGTGCTTCGTCAGGGACTGAAGCGCTTCCCGCACGTGGACCTGTGGCTGGGCCACGAGGTGG
AGTCCTTCGTCCAGGACGAAGACGGCGTCACCGCCCGCGTGAAGGAGGTCGCGGGGGAGCGTGCCGTCAACGTGCGCGCG
CGCTTCCTGCTCGCGTGCGACGGCTCGCACAGCTCCATCCGCCGGCGGCTGGGTCTGAAGCTCGTGGGGACGACGGCGCT
GGAGCACTCGCTGGCCATCACCGTGAAGACGCGCTCACCCGAGCCCGAATTCACCAGCTACCTGTGCGGCCCCGTGCGCC
GGGGGTTCATCGCGCGCACCGCGCCGAACGAGATTCGCTTCGACATCATCCTGGAGCCAGATGCGGACCTGAAGGCGGCG
CGCTCGCTCGAGAACGTGCGGCGGCTGATCGGCTACTACCTGGACCCGGATTCGGTGGAGCTCGACTCCGTCAAGATCTT
CTCGTACCACAGCCGCATGTCCGAGCAGTGGCGGGTGGGCCGCGTGTTCCTCCTGGGCGACGCGGCGCACCTGATGCCGC
CCTTCCTGGGGCAGGGGCTCTGCGCGGGCCTCCGGGACGCGGCGAACCTGACCTGGAAGCTCGGGCTGGTGCTCGCGGGC
GCGGCGGATGCGTCGCTGCTCGACACCTACGAGGAAGAGCGGCGTGGCCACGTGTCGGAGGTGATTCGCGGCTCGGACGC
CATGGGCCGGGTGATGATGTCGGGCGGGCGGGTGATGGCTCGCGTCCGCAACGCGCTCATCCAGGTGATGTACCGGCTGC
CGGTGACGGGCGACTTCATCCGCGACTACAAGGTGAAGCCGCAGATGCCGCTGCGCCGGGGCTTCATGCTCGGCGCCCAA
CGCGAGAAGGGGGACGTGCCGGAAGGCTCCTACTTCCCGCAGCCGCGCGTGGAGCGGCCCGACGGGGAGACGGCGCTGCT
GGATGACTGCCTGGGCGAGGGCTTCGTGGTGCTGACGCGTCCAGGTGCTTCCCAGGAGGCCCAGCGCGAGGCACGGGCCC
TGGCGGACGAACTCGGAGCACGCTGGTGGCAGGTGGCCGCGGCGGACCGCGCGGGAAGTGGCGGGCCGGACACGCTGGTG
GACCTGGACGGCCGGCTGGGCGCCTGGTTCGTGCAGTACGCGGCCGACCTCGTGGTGCTCCGGCCGGACCGCTACGTGTT
CGGCATCGCAGGGGGTGGCAAGCGGGGCCACCTCCTGGGCTCGCTCAAGGGCCGCGTCCGCCCTCACTCGCGTCCGAGTG
GCGCGGAGGTCCGGCGGGCGGGCTGA

Upstream 100 bases:

>100_bases
GGCTTCCGAGTGAAAACAGGACATTCCAGGTCGTGGCTGATTTTGATATCGAAATGACTCAAAGGCAGCTCAGCACACGT
ACTCGCAACGGGAGGGAGAG

Downstream 100 bases:

>100_bases
AACGCGGGGGAACGGAAAAACAACAGGCGCCCGGGCCGGGGCGCCCTACGACCGCGAAGTGGGGCTGCGGGGAGGCTCAG
GCCGCGGCGGCGGACTGGAC

Product: PheA/TfdB family FAD-binding monooxygenase

Products: NA

Alternate protein names: 3-HCI hydroxylase; 3-HPP hydroxylase [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MAPESVDVIIVGSGPVGAMAANLLGQQGIRTLVVEREVTPHGQSRAISVDDEGQRIFQSAGLVGDLGAGFYPCKRLQYLN
DSLRSLAEVDFTRLDRPFGYVPAAFFQQPRMEAVLRQGLKRFPHVDLWLGHEVESFVQDEDGVTARVKEVAGERAVNVRA
RFLLACDGSHSSIRRRLGLKLVGTTALEHSLAITVKTRSPEPEFTSYLCGPVRRGFIARTAPNEIRFDIILEPDADLKAA
RSLENVRRLIGYYLDPDSVELDSVKIFSYHSRMSEQWRVGRVFLLGDAAHLMPPFLGQGLCAGLRDAANLTWKLGLVLAG
AADASLLDTYEEERRGHVSEVIRGSDAMGRVMMSGGRVMARVRNALIQVMYRLPVTGDFIRDYKVKPQMPLRRGFMLGAQ
REKGDVPEGSYFPQPRVERPDGETALLDDCLGEGFVVLTRPGASQEAQREARALADELGARWWQVAAADRAGSGGPDTLV
DLDGRLGAWFVQYAADLVVLRPDRYVFGIAGGGKRGHLLGSLKGRVRPHSRPSGAEVRRAG

Sequences:

>Translated_541_residues
MAPESVDVIIVGSGPVGAMAANLLGQQGIRTLVVEREVTPHGQSRAISVDDEGQRIFQSAGLVGDLGAGFYPCKRLQYLN
DSLRSLAEVDFTRLDRPFGYVPAAFFQQPRMEAVLRQGLKRFPHVDLWLGHEVESFVQDEDGVTARVKEVAGERAVNVRA
RFLLACDGSHSSIRRRLGLKLVGTTALEHSLAITVKTRSPEPEFTSYLCGPVRRGFIARTAPNEIRFDIILEPDADLKAA
RSLENVRRLIGYYLDPDSVELDSVKIFSYHSRMSEQWRVGRVFLLGDAAHLMPPFLGQGLCAGLRDAANLTWKLGLVLAG
AADASLLDTYEEERRGHVSEVIRGSDAMGRVMMSGGRVMARVRNALIQVMYRLPVTGDFIRDYKVKPQMPLRRGFMLGAQ
REKGDVPEGSYFPQPRVERPDGETALLDDCLGEGFVVLTRPGASQEAQREARALADELGARWWQVAAADRAGSGGPDTLV
DLDGRLGAWFVQYAADLVVLRPDRYVFGIAGGGKRGHLLGSLKGRVRPHSRPSGAEVRRAG
>Mature_540_residues
APESVDVIIVGSGPVGAMAANLLGQQGIRTLVVEREVTPHGQSRAISVDDEGQRIFQSAGLVGDLGAGFYPCKRLQYLND
SLRSLAEVDFTRLDRPFGYVPAAFFQQPRMEAVLRQGLKRFPHVDLWLGHEVESFVQDEDGVTARVKEVAGERAVNVRAR
FLLACDGSHSSIRRRLGLKLVGTTALEHSLAITVKTRSPEPEFTSYLCGPVRRGFIARTAPNEIRFDIILEPDADLKAAR
SLENVRRLIGYYLDPDSVELDSVKIFSYHSRMSEQWRVGRVFLLGDAAHLMPPFLGQGLCAGLRDAANLTWKLGLVLAGA
ADASLLDTYEEERRGHVSEVIRGSDAMGRVMMSGGRVMARVRNALIQVMYRLPVTGDFIRDYKVKPQMPLRRGFMLGAQR
EKGDVPEGSYFPQPRVERPDGETALLDDCLGEGFVVLTRPGASQEAQREARALADELGARWWQVAAADRAGSGGPDTLVD
LDGRLGAWFVQYAADLVVLRPDRYVFGIAGGGKRGHLLGSLKGRVRPHSRPSGAEVRRAG

Specific function: Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3- hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI) [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pheA/tfdB FAD monooxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786543, Length=549, Percent_Identity=35.7012750455373, Blast_Score=299, Evalue=3e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 59426; Mature: 59295

Theoretical pI: Translated: 8.66; Mature: 8.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPESVDVIIVGSGPVGAMAANLLGQQGIRTLVVEREVTPHGQSRAISVDDEGQRIFQSA
CCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHC
GLVGDLGAGFYPCKRLQYLNDSLRSLAEVDFTRLDRPFGYVPAAFFQQPRMEAVLRQGLK
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHH
RFPHVDLWLGHEVESFVQDEDGVTARVKEVAGERAVNVRARFLLACDGSHSSIRRRLGLK
HCCCEEEEECCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEEEEEECCCHHHHHHHHCCE
LVGTTALEHSLAITVKTRSPEPEFTSYLCGPVRRGFIARTAPNEIRFDIILEPDADLKAA
EEEHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCHHHH
RSLENVRRLIGYYLDPDSVELDSVKIFSYHSRMSEQWRVGRVFLLGDAAHLMPPFLGQGL
HHHHHHHHHHHEECCCCCCEECCEEEEEHHHHHHHCCCEEEEEEECCHHHHCCHHHHHHH
CAGLRDAANLTWKLGLVLAGAADASLLDTYEEERRGHVSEVIRGSDAMGRVMMSGGRVMA
HHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHCCCHHHH
RVRNALIQVMYRLPVTGDFIRDYKVKPQMPLRRGFMLGAQREKGDVPEGSYFPQPRVERP
HHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCC
DGETALLDDCLGEGFVVLTRPGASQEAQREARALADELGARWWQVAAADRAGSGGPDTLV
CCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHEEEHHHCCCCCCCCCCEE
DLDGRLGAWFVQYAADLVVLRPDRYVFGIAGGGKRGHLLGSLKGRVRPHSRPSGAEVRRA
ECCCCHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
G
C
>Mature Secondary Structure 
APESVDVIIVGSGPVGAMAANLLGQQGIRTLVVEREVTPHGQSRAISVDDEGQRIFQSA
CCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEECCCHHHHHHHHC
GLVGDLGAGFYPCKRLQYLNDSLRSLAEVDFTRLDRPFGYVPAAFFQQPRMEAVLRQGLK
CCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHH
RFPHVDLWLGHEVESFVQDEDGVTARVKEVAGERAVNVRARFLLACDGSHSSIRRRLGLK
HCCCEEEEECCHHHHHHCCCCCHHHHHHHHHCCCEEEEEEEEEEEECCCHHHHHHHHCCE
LVGTTALEHSLAITVKTRSPEPEFTSYLCGPVRRGFIARTAPNEIRFDIILEPDADLKAA
EEEHHHCCCEEEEEEEECCCCCHHHHHHHHHHHCCEEEECCCCCEEEEEEECCCCCHHHH
RSLENVRRLIGYYLDPDSVELDSVKIFSYHSRMSEQWRVGRVFLLGDAAHLMPPFLGQGL
HHHHHHHHHHHEECCCCCCEECCEEEEEHHHHHHHCCCEEEEEEECCHHHHCCHHHHHHH
CAGLRDAANLTWKLGLVLAGAADASLLDTYEEERRGHVSEVIRGSDAMGRVMMSGGRVMA
HHHHHHHCCCEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHCCCHHHH
RVRNALIQVMYRLPVTGDFIRDYKVKPQMPLRRGFMLGAQREKGDVPEGSYFPQPRVERP
HHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHEECCCCCCCCCCCCCCCCCCCCCCC
DGETALLDDCLGEGFVVLTRPGASQEAQREARALADELGARWWQVAAADRAGSGGPDTLV
CCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCHHEEEHHHCCCCCCCCCCEE
DLDGRLGAWFVQYAADLVVLRPDRYVFGIAGGGKRGHLLGSLKGRVRPHSRPSGAEVRRA
ECCCCHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCEEECCCCCCCCCCCCCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA