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The map label for this gene is uvrA [H]

Identifier: 108762926

GI number: 108762926

Start: 4019866

End: 4022418

Strand: Direct

Name: uvrA [H]

Synonym: MXAN_3452

Alternate gene names: 108762926

Gene position: 4019866-4022418 (Clockwise)

Preceding gene: 108761146

Following gene: 108759828

Centisome position: 43.98

GC content: 69.57

Gene sequence:

>2553_bases
ATGGCCAGGGCTCGTCGTTCGAAGCAGCAATCAGACTCGTCAGGTACCACCGAGCAAGGCTTCGTGGAGGTGCGCGGCGC
CCGCCAGCACAACCTGAAGAACGTCGACGTCCGAATTCCCCGCGACGCGTTCGTTGTGTTCACCGGCGTGTCGGGCTCGG
GCAAGTCGTCGCTGGCCTTCGGCACGCTCTACGCGGAAGCGCAGCGGCGGTACTTCGAATCCGTGGCCCCCTATGCGCGC
CGTCTCATCGACCAGGCGGGTGTGCCGGAGGTCGACGCCATCGACGGGCTGCCCCCTGCCGTGGCGCTCCAGCAGCACCG
GGGCGCGCCCACCACGCGTTCGTCCGTGGGGAGCGTGACGACGTTGGCGAACTCGTTGCGGTTGCTGTACTCGCGCGCGG
GCACGTATCCGCGAGGGCAGCCGCACCTGGATTCGGATGCCTTTTCCCCCAACACCCCCGCGGGCGCGTGCCCCAAGTGC
CACGGGCTGGGCCGCATCTACGACGCCACCGAGAAGTCGATGGTGCCGGATGACTCGCTCACCATCCGGGAGCGGGCGAT
TGCCGCCTGGCCGCCCGCGTGGCACGGCCAGAACCTGCGCGACATCCTGGTGACGCTCGGCTACGACGTCGACCGGCCGT
GGCGCGAGCTGCCGAAGAAGGACCGGGACTGGATTCTCTTCACGGAGGAGCAGCCCACGGTGCCCGTCTACGCGGGCTTC
ACTCCGGCCGAGACGCAGCGGGCCCTCAAGCGCAAGGCGGCGCCCAGCTACATGGGCACCTTCACGGGCGCCCGGCGCTA
CGTGCTCCAGACCTTCGCCACCACGCAGAGCGCGCTGATGAAGAGGCGCGTCTCGCAGTACATGGTGAGCGGCGACTGCC
CCGAATGCCACGGCAAGCGCCTGCGCCGCGAGTCCCTGTCCGTCACCTTCGCGGGGCTCGACATCGGCGAGCTGTCGCGT
CTGCCGCTCAGTGAACTCACGGACCTGCTCGCGCCCGTGGCGGATGGGACGGCCAAGGACGTGGCGGCGCTTGCCCGTGT
GCATCCGGAGAAGGCGCTGGTGGCCCAGCGCATCGCCCACGACGTGTTGGCGCGCGTCAACGTCCTGACGGAGCTGGGCC
TGGGCTACCTGTCGCTCGAGCGCGGAACGCCGACGCTGTCTCCTGGCGAGCTCCAGCGCTTGCGGCTGGCCACGCAGGTG
CGCTCCAACCTGTTCGGCGTGGTGTACGTGCTCGATGAGCCGTCCGCTGGGCTGCACCCCGCGGACACCGCGGCGCTGCT
GAAGGCGCTGGACCAGCTCAAGGGCTCAGGCAACTCGCTGTTCGTGGTGGAGCACGAGGTGGATGTCATCCGCCACGCGG
ACTGGATTGTCGACGTGGGGCCCGACGCGGGCGAGCAGGGCGGGCAGATTCTCTACAGCGGTCCGCTCGAAGGCCTGAAG
GCGGTGAAGGCGTCCCGGACGCGGCGCTATCTCTTCGGCGACGCGGAGAAGCACCGCGGCACGCGGCGTTCGCCCAAGGG
CTGGCTGCGCCTGCAGGGCGTGTCGCGCAACAACCTGAAGGAAGTGGACGTCGACTTCCCGCTGGGCGTCCTCACCACGG
TGACGGGGGTCTCCGGCTCCGGGAAGTCGAGCCTCGTGAGCCAGGTCCTGGTGGAGCTGGTGGCCGGACACCTGGGCCAC
GCGGTGCCGGAGAACGAGGACGAGGGAGAGGAGCTGGAGCGCACGGTCATCCACACCACCGGCGGCAGGATTGCCTCCGG
CATGGAGGGCATCAAGCGCCTGGTGCAGGTAGACCAGAAGCCCATTGGACGCACGCCGCGCTCCAACCTGGCGACGTACA
CGGGGCTGTTCGACAACGTCCGCAAGCTCTTCGCCGCGACGCCCGCCGCACGCTCCCGGCGTTATGACGTGGGACGCTTC
TCCTTCAACGTGGCCAAGGGCCGCTGCGAGACGTGCGAAGGTGAGGGCTTCGTCAGCGTGGAGCTGCTCTTCCTGCCCAG
CGTCTACGCGCCGTGCCCCACGTGTCAGGGGGCCCGCTACAACGCCAAGACGCTGGAGATTCAGTACCGGGGCAAGAACA
TCGCCGAGGTGCTGGGCATGACGGTGGACGCGGCCCACGACTTCTTCAGCGAGGACCCGCTGGTGCAGCGGCCGCTCGCC
GTCCTGCGGGAGGTGGGGTTGGGATACCTGCGGCTGGGGCAGCCCGCGACGGAGTTGTCCGGCGGCGAGGCCCAACGCAT
CAAGCTGGCCACGGAGCTTCAGCGGGCCCAGCGCGGCAGCTCGCTGTACGTGCTGGACGAACCCACCACGGGCCTGCACC
CCTCCGACGTGGACAAGCTGATGACGCAGTTGGAGGGGCTGGTGGCCTCCGGCAACACCGTCATCCTCGTCGAGCACGAC
ATGCGCGTGGTGGCCGCGAGCGACTGGGTCATCGACATGGGCCCGGGCGCTGGGGACAAGGGCGGGCGGGTGGTGGTGGC
GGGCCCACCGGAGGAGGTGGTGGGCCTGCCCTACAGCCAGACCGCGCCCTTCCTGGAGGAGGCGCTGGGCTGA

Upstream 100 bases:

>100_bases
AGCCCGGGGGCAGTGGCCCGTGTTCGCGCGTGTCTCCCACATCTGCCTCCGGTACAACGCCGCCGGAATTCATCCCTTCC
GACAACTCAGCGTGGGGCGT

Downstream 100 bases:

>100_bases
GCTTCCAGCGCCCGTCGGAGCCTCCGAGCCGTGGCCGTGAGGGCCGCCGGGCTCGGAGGTGGAGGCCGCGGAATCAGCGC
GCCTGCGCCTGTGCCGCGGG

Product: UvrABC system protein A

Products: NA

Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]

Number of amino acids: Translated: 850; Mature: 849

Protein sequence:

>850_residues
MARARRSKQQSDSSGTTEQGFVEVRGARQHNLKNVDVRIPRDAFVVFTGVSGSGKSSLAFGTLYAEAQRRYFESVAPYAR
RLIDQAGVPEVDAIDGLPPAVALQQHRGAPTTRSSVGSVTTLANSLRLLYSRAGTYPRGQPHLDSDAFSPNTPAGACPKC
HGLGRIYDATEKSMVPDDSLTIRERAIAAWPPAWHGQNLRDILVTLGYDVDRPWRELPKKDRDWILFTEEQPTVPVYAGF
TPAETQRALKRKAAPSYMGTFTGARRYVLQTFATTQSALMKRRVSQYMVSGDCPECHGKRLRRESLSVTFAGLDIGELSR
LPLSELTDLLAPVADGTAKDVAALARVHPEKALVAQRIAHDVLARVNVLTELGLGYLSLERGTPTLSPGELQRLRLATQV
RSNLFGVVYVLDEPSAGLHPADTAALLKALDQLKGSGNSLFVVEHEVDVIRHADWIVDVGPDAGEQGGQILYSGPLEGLK
AVKASRTRRYLFGDAEKHRGTRRSPKGWLRLQGVSRNNLKEVDVDFPLGVLTTVTGVSGSGKSSLVSQVLVELVAGHLGH
AVPENEDEGEELERTVIHTTGGRIASGMEGIKRLVQVDQKPIGRTPRSNLATYTGLFDNVRKLFAATPAARSRRYDVGRF
SFNVAKGRCETCEGEGFVSVELLFLPSVYAPCPTCQGARYNAKTLEIQYRGKNIAEVLGMTVDAAHDFFSEDPLVQRPLA
VLREVGLGYLRLGQPATELSGGEAQRIKLATELQRAQRGSSLYVLDEPTTGLHPSDVDKLMTQLEGLVASGNTVILVEHD
MRVVAASDWVIDMGPGAGDKGGRVVVAGPPEEVVGLPYSQTAPFLEEALG

Sequences:

>Translated_850_residues
MARARRSKQQSDSSGTTEQGFVEVRGARQHNLKNVDVRIPRDAFVVFTGVSGSGKSSLAFGTLYAEAQRRYFESVAPYAR
RLIDQAGVPEVDAIDGLPPAVALQQHRGAPTTRSSVGSVTTLANSLRLLYSRAGTYPRGQPHLDSDAFSPNTPAGACPKC
HGLGRIYDATEKSMVPDDSLTIRERAIAAWPPAWHGQNLRDILVTLGYDVDRPWRELPKKDRDWILFTEEQPTVPVYAGF
TPAETQRALKRKAAPSYMGTFTGARRYVLQTFATTQSALMKRRVSQYMVSGDCPECHGKRLRRESLSVTFAGLDIGELSR
LPLSELTDLLAPVADGTAKDVAALARVHPEKALVAQRIAHDVLARVNVLTELGLGYLSLERGTPTLSPGELQRLRLATQV
RSNLFGVVYVLDEPSAGLHPADTAALLKALDQLKGSGNSLFVVEHEVDVIRHADWIVDVGPDAGEQGGQILYSGPLEGLK
AVKASRTRRYLFGDAEKHRGTRRSPKGWLRLQGVSRNNLKEVDVDFPLGVLTTVTGVSGSGKSSLVSQVLVELVAGHLGH
AVPENEDEGEELERTVIHTTGGRIASGMEGIKRLVQVDQKPIGRTPRSNLATYTGLFDNVRKLFAATPAARSRRYDVGRF
SFNVAKGRCETCEGEGFVSVELLFLPSVYAPCPTCQGARYNAKTLEIQYRGKNIAEVLGMTVDAAHDFFSEDPLVQRPLA
VLREVGLGYLRLGQPATELSGGEAQRIKLATELQRAQRGSSLYVLDEPTTGLHPSDVDKLMTQLEGLVASGNTVILVEHD
MRVVAASDWVIDMGPGAGDKGGRVVVAGPPEEVVGLPYSQTAPFLEEALG
>Mature_849_residues
ARARRSKQQSDSSGTTEQGFVEVRGARQHNLKNVDVRIPRDAFVVFTGVSGSGKSSLAFGTLYAEAQRRYFESVAPYARR
LIDQAGVPEVDAIDGLPPAVALQQHRGAPTTRSSVGSVTTLANSLRLLYSRAGTYPRGQPHLDSDAFSPNTPAGACPKCH
GLGRIYDATEKSMVPDDSLTIRERAIAAWPPAWHGQNLRDILVTLGYDVDRPWRELPKKDRDWILFTEEQPTVPVYAGFT
PAETQRALKRKAAPSYMGTFTGARRYVLQTFATTQSALMKRRVSQYMVSGDCPECHGKRLRRESLSVTFAGLDIGELSRL
PLSELTDLLAPVADGTAKDVAALARVHPEKALVAQRIAHDVLARVNVLTELGLGYLSLERGTPTLSPGELQRLRLATQVR
SNLFGVVYVLDEPSAGLHPADTAALLKALDQLKGSGNSLFVVEHEVDVIRHADWIVDVGPDAGEQGGQILYSGPLEGLKA
VKASRTRRYLFGDAEKHRGTRRSPKGWLRLQGVSRNNLKEVDVDFPLGVLTTVTGVSGSGKSSLVSQVLVELVAGHLGHA
VPENEDEGEELERTVIHTTGGRIASGMEGIKRLVQVDQKPIGRTPRSNLATYTGLFDNVRKLFAATPAARSRRYDVGRFS
FNVAKGRCETCEGEGFVSVELLFLPSVYAPCPTCQGARYNAKTLEIQYRGKNIAEVLGMTVDAAHDFFSEDPLVQRPLAV
LREVGLGYLRLGQPATELSGGEAQRIKLATELQRAQRGSSLYVLDEPTTGLHPSDVDKLMTQLEGLVASGNTVILVEHDM
RVVAASDWVIDMGPGAGDKGGRVVVAGPPEEVVGLPYSQTAPFLEEALG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h

COG id: COG0178

COG function: function code L; Excinuclease ATPase subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI2367343, Length=712, Percent_Identity=39.4662921348315, Blast_Score=503, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017871 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 92214; Mature: 92083

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARARRSKQQSDSSGTTEQGFVEVRGARQHNLKNVDVRIPRDAFVVFTGVSGSGKSSLAF
CCCCHHHHHCCCCCCCCCCCEEEECCCHHCCCCCCEEEECCCEEEEEECCCCCCCCCHHH
GTLYAEAQRRYFESVAPYARRLIDQAGVPEVDAIDGLPPAVALQQHRGAPTTRSSVGSVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHH
TLANSLRLLYSRAGTYPRGQPHLDSDAFSPNTPAGACPKCHGLGRIYDATEKSMVPDDSL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHCCCCCCCC
TIRERAIAAWPPAWHGQNLRDILVTLGYDVDRPWRELPKKDRDWILFTEEQPTVPVYAGF
HHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCCCCEEEECC
TPAETQRALKRKAAPSYMGTFTGARRYVLQTFATTQSALMKRRVSQYMVSGDCPECHGKR
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LRRESLSVTFAGLDIGELSRLPLSELTDLLAPVADGTAKDVAALARVHPEKALVAQRIAH
HHHHHCEEEEECCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHH
DVLARVNVLTELGLGYLSLERGTPTLSPGELQRLRLATQVRSNLFGVVYVLDEPSAGLHP
HHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCC
ADTAALLKALDQLKGSGNSLFVVEHEVDVIRHADWIVDVGPDAGEQGGQILYSGPLEGLK
CHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCEEEECCCCCCCCCCEEEECCCHHHHH
AVKASRTRRYLFGDAEKHRGTRRSPKGWLRLQGVSRNNLKEVDVDFPLGVLTTVTGVSGS
HHHHHHHHHHEECCHHHHCCCCCCCCCEEEEECCCCCCCEEECCCCCHHHHHHHCCCCCC
GKSSLVSQVLVELVAGHLGHAVPENEDEGEELERTVIHTTGGRIASGMEGIKRLVQVDQK
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCC
PIGRTPRSNLATYTGLFDNVRKLFAATPAARSRRYDVGRFSFNVAKGRCETCEGEGFVSV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEE
ELLFLPSVYAPCPTCQGARYNAKTLEIQYRGKNIAEVLGMTVDAAHDFFSEDPLVQRPLA
EEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCHHHHHHHHCCCCCHHHHHHH
VLREVGLGYLRLGQPATELSGGEAQRIKLATELQRAQRGSSLYVLDEPTTGLHPSDVDKL
HHHHCCCCEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
MTQLEGLVASGNTVILVEHDMRVVAASDWVIDMGPGAGDKGGRVVVAGPPEEVVGLPYSQ
HHHHHHHEECCCEEEEEECCCEEEEECCEEEECCCCCCCCCCEEEEECCCHHHCCCCCCC
TAPFLEEALG
CCHHHHHHCC
>Mature Secondary Structure 
ARARRSKQQSDSSGTTEQGFVEVRGARQHNLKNVDVRIPRDAFVVFTGVSGSGKSSLAF
CCCHHHHHCCCCCCCCCCCEEEECCCHHCCCCCCEEEECCCEEEEEECCCCCCCCCHHH
GTLYAEAQRRYFESVAPYARRLIDQAGVPEVDAIDGLPPAVALQQHRGAPTTRSSVGSVT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHH
TLANSLRLLYSRAGTYPRGQPHLDSDAFSPNTPAGACPKCHGLGRIYDATEKSMVPDDSL
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCHHHCCCCCCCC
TIRERAIAAWPPAWHGQNLRDILVTLGYDVDRPWRELPKKDRDWILFTEEQPTVPVYAGF
HHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHHHCCCCCCCEEEEECCCCCCEEEECC
TPAETQRALKRKAAPSYMGTFTGARRYVLQTFATTQSALMKRRVSQYMVSGDCPECHGKR
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LRRESLSVTFAGLDIGELSRLPLSELTDLLAPVADGTAKDVAALARVHPEKALVAQRIAH
HHHHHCEEEEECCCHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHH
DVLARVNVLTELGLGYLSLERGTPTLSPGELQRLRLATQVRSNLFGVVYVLDEPSAGLHP
HHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCC
ADTAALLKALDQLKGSGNSLFVVEHEVDVIRHADWIVDVGPDAGEQGGQILYSGPLEGLK
CHHHHHHHHHHHHCCCCCEEEEEECCHHHHHCCCEEEECCCCCCCCCCEEEECCCHHHHH
AVKASRTRRYLFGDAEKHRGTRRSPKGWLRLQGVSRNNLKEVDVDFPLGVLTTVTGVSGS
HHHHHHHHHHEECCHHHHCCCCCCCCCEEEEECCCCCCCEEECCCCCHHHHHHHCCCCCC
GKSSLVSQVLVELVAGHLGHAVPENEDEGEELERTVIHTTGGRIASGMEGIKRLVQVDQK
CHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCC
PIGRTPRSNLATYTGLFDNVRKLFAATPAARSRRYDVGRFSFNVAKGRCETCEGEGFVSV
CCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEECCCCCCCCCCCCEEEE
ELLFLPSVYAPCPTCQGARYNAKTLEIQYRGKNIAEVLGMTVDAAHDFFSEDPLVQRPLA
EEEEECCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCHHHHHHHHCCCCCHHHHHHH
VLREVGLGYLRLGQPATELSGGEAQRIKLATELQRAQRGSSLYVLDEPTTGLHPSDVDKL
HHHHCCCCEEECCCCHHHCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHH
MTQLEGLVASGNTVILVEHDMRVVAASDWVIDMGPGAGDKGGRVVVAGPPEEVVGLPYSQ
HHHHHHHEECCCEEEEEECCCEEEEECCEEEECCCCCCCCCCEEEEECCCHHHCCCCCCC
TAPFLEEALG
CCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8269961 [H]