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The map label for this gene is speB1 [H]

Identifier: 108761940

GI number: 108761940

Start: 5479665

End: 5480702

Strand: Direct

Name: speB1 [H]

Synonym: MXAN_4431

Alternate gene names: 108761940

Gene position: 5479665-5480702 (Clockwise)

Preceding gene: 108757276

Following gene: 108757026

Centisome position: 59.95

GC content: 69.17

Gene sequence:

>1038_bases
ATGGCTACCCACTTCGACCCCAGCGCCGCCGCCCAGCCGGACTCCGGCGTGTTCGGCCTCCCCCACTCCCCGGAAGAGGC
GCACGTCATCCTCATCCCCGTTCCCTTCGAGGCCACCACCAGTTACGGCGGTGGCACGTCCGAGGGGCCAACCGCCGTCC
TGGAAGCCAGCCGGCAGGTCGACCTCTTCGACGTGGAGACGGGTCGTCCCTACGAGCGTGGCATCGCCATGCTCCCCGAG
CCCCAGGAGCTGCGCGACTGGAACACCCGCGCCAAGGAGCGCGCCCAGGTCGTCATCGAGGCCGGTGGCATCCACTCCGG
CGAGGCCGCGCTGATTCAGGCCGCGCAGGACGTGAATGTCCTCTGCGACCAGATGAACGAGCACGTCTACCGCACCACCA
AGCACTGGTTGGACCAGGGCAAGCGCGTGGCCGCGGTGGGCGGTGACCACTCCATCTCCTACGGCATCATCCGCGCGCAC
GCGGAGAAGTACCCCGGCCTGGGCGTGCTGCACCTGGACGCGCACGCCGACCTGCGCGTGGCCTACGAGGGCTTCACCTG
GTCCCACGCGTCCATCATGTACAACGTCGCGGAGCGCATCCCCGGCGTGAAGACGCTGGTCCAGGTGGGCCTGCGCGACA
TGAGCGCGGAGGAGTACCAGTACATCGCGGACTCCAACGGCCGCGTGCACGGCTTCTTCGACGCCGTCCTCCAGAACAAG
CGCTTCGACGGCGTGCCCTGGAACCGGCAGGTGGATGAGATGGTCGCCCTGCTCCCGAAGCAGGTCTACCTGTCCTTCGA
CATCGACGGGCTGGACCCCGTGCTCTGCCCCCACACGGGCACCCCGGTGCCCGGCGGACTGTCCTTCGCCGAGGCCGTGG
CCCTCATCGCCGGCGTGGTCCGCTCCGGGCGCACCATCGTGGGCTTCGACCTCACCGAGGTGGCCCCCGACCCCGAGGGC
GGCGAGTGGGACGGCAACGTCGGCGCCCGGCTTCTGTACAAGATGATTGGCTGGATGCTGAAGTCGCAGCAGGCCTGA

Upstream 100 bases:

>100_bases
GAGAAACATCAGGTGCTGGCCGGGCGTTTCGACGTCAAGGAACGCATCGAGAAGTAACAGACCATTGCGCCCCGACACCG
GGCCTTTATCCTGCGCCGCC

Downstream 100 bases:

>100_bases
CGTCTCGTCACGCGAAGCGCCCGTGAAGGGATGCCATCGCGTGTCAGGTGCTCCGCGGCAGCATCAGGCTGAACGTGGAG
CCCTCGCCGGGTCGTGACTG

Product: putative agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase 1; AUH 1 [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MATHFDPSAAAQPDSGVFGLPHSPEEAHVILIPVPFEATTSYGGGTSEGPTAVLEASRQVDLFDVETGRPYERGIAMLPE
PQELRDWNTRAKERAQVVIEAGGIHSGEAALIQAAQDVNVLCDQMNEHVYRTTKHWLDQGKRVAAVGGDHSISYGIIRAH
AEKYPGLGVLHLDAHADLRVAYEGFTWSHASIMYNVAERIPGVKTLVQVGLRDMSAEEYQYIADSNGRVHGFFDAVLQNK
RFDGVPWNRQVDEMVALLPKQVYLSFDIDGLDPVLCPHTGTPVPGGLSFAEAVALIAGVVRSGRTIVGFDLTEVAPDPEG
GEWDGNVGARLLYKMIGWMLKSQQA

Sequences:

>Translated_345_residues
MATHFDPSAAAQPDSGVFGLPHSPEEAHVILIPVPFEATTSYGGGTSEGPTAVLEASRQVDLFDVETGRPYERGIAMLPE
PQELRDWNTRAKERAQVVIEAGGIHSGEAALIQAAQDVNVLCDQMNEHVYRTTKHWLDQGKRVAAVGGDHSISYGIIRAH
AEKYPGLGVLHLDAHADLRVAYEGFTWSHASIMYNVAERIPGVKTLVQVGLRDMSAEEYQYIADSNGRVHGFFDAVLQNK
RFDGVPWNRQVDEMVALLPKQVYLSFDIDGLDPVLCPHTGTPVPGGLSFAEAVALIAGVVRSGRTIVGFDLTEVAPDPEG
GEWDGNVGARLLYKMIGWMLKSQQA
>Mature_344_residues
ATHFDPSAAAQPDSGVFGLPHSPEEAHVILIPVPFEATTSYGGGTSEGPTAVLEASRQVDLFDVETGRPYERGIAMLPEP
QELRDWNTRAKERAQVVIEAGGIHSGEAALIQAAQDVNVLCDQMNEHVYRTTKHWLDQGKRVAAVGGDHSISYGIIRAHA
EKYPGLGVLHLDAHADLRVAYEGFTWSHASIMYNVAERIPGVKTLVQVGLRDMSAEEYQYIADSNGRVHGFFDAVLQNKR
FDGVPWNRQVDEMVALLPKQVYLSFDIDGLDPVLCPHTGTPVPGGLSFAEAVALIAGVVRSGRTIVGFDLTEVAPDPEGG
EWDGNVGARLLYKMIGWMLKSQQA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=240, Percent_Identity=30.8333333333333, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI10947139, Length=223, Percent_Identity=27.8026905829596, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502215, Length=229, Percent_Identity=25.764192139738, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1789306, Length=311, Percent_Identity=31.5112540192926, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6325146, Length=297, Percent_Identity=24.5791245791246, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24638886, Length=238, Percent_Identity=29.4117647058824, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 37522; Mature: 37390

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATHFDPSAAAQPDSGVFGLPHSPEEAHVILIPVPFEATTSYGGGTSEGPTAVLEASRQV
CCCCCCCCCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCE
DLFDVETGRPYERGIAMLPEPQELRDWNTRAKERAQVVIEAGGIHSGEAALIQAAQDVNV
EEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHH
LCDQMNEHVYRTTKHWLDQGKRVAAVGGDHSISYGIIRAHAEKYPGLGVLHLDAHADLRV
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHEEEHHHHCCCCEEEEECCCCCEEE
AYEGFTWSHASIMYNVAERIPGVKTLVQVGLRDMSAEEYQYIADSNGRVHGFFDAVLQNK
EEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHEECCCCEEEHHHHHHHCCC
RFDGVPWNRQVDEMVALLPKQVYLSFDIDGLDPVLCPHTGTPVPGGLSFAEAVALIAGVV
CCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHH
RSGRTIVGFDLTEVAPDPEGGEWDGNVGARLLYKMIGWMLKSQQA
HCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATHFDPSAAAQPDSGVFGLPHSPEEAHVILIPVPFEATTSYGGGTSEGPTAVLEASRQV
CCCCCCCCCCCCCCCEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCE
DLFDVETGRPYERGIAMLPEPQELRDWNTRAKERAQVVIEAGGIHSGEAALIQAAQDVNV
EEEECCCCCCHHHCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCHHHHHHHHHHHH
LCDQMNEHVYRTTKHWLDQGKRVAAVGGDHSISYGIIRAHAEKYPGLGVLHLDAHADLRV
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEHHHEEEHHHHCCCCEEEEECCCCCEEE
AYEGFTWSHASIMYNVAERIPGVKTLVQVGLRDMSAEEYQYIADSNGRVHGFFDAVLQNK
EEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHEECCCCEEEHHHHHHHCCC
RFDGVPWNRQVDEMVALLPKQVYLSFDIDGLDPVLCPHTGTPVPGGLSFAEAVALIAGVV
CCCCCCCCCCHHHHHHHCCCEEEEEEECCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHH
RSGRTIVGFDLTEVAPDPEGGEWDGNVGARLLYKMIGWMLKSQQA
HCCCEEEEEEHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]