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The map label for this gene is murA

Identifier: 108761915

GI number: 108761915

Start: 6142330

End: 6143592

Strand: Direct

Name: murA

Synonym: MXAN_4909

Alternate gene names: 108761915

Gene position: 6142330-6143592 (Clockwise)

Preceding gene: 108759552

Following gene: 108763417

Centisome position: 67.2

GC content: 69.75

Gene sequence:

>1263_bases
ATGGACAAGATCGTCATCAAGGGCGGCCAGGCGCTGCACGGCGAAGTGCAGGCCTCGGGCGCGAAGAACGCGGCGCTGCC
CATCCTCGCCTCGGCGCTGCTGGCCGACGGCACATCCACCTACCGCAACGTGCCGGCCCTGGCGGATGTCGCCACCATGC
TCAAGGTGCTGCGCACCATGGGCTGCGACGCGGAGCGCGACTCGGAGACGACGGACGTCTGCCGGGTCGGCGTCAACGGC
CACATCACCCCGGAGGCGCCGTACGACCTGGTGAAGACGATGCGCGCCAGCGTGCTGGTGCTGGGGCCGCTGGTCGCCCG
CTTCGGCCGGGCGCGGGTGTCCATGCCGGGCGGGTGCGCCATTGGCGCGCGGCCCATCGACCAGCACCTCAAGGGGCTCA
AGGCGCTGGGCGCGGACATCCACCTCACGGAAGGCTACGTGGAGGCCACGGCGAAGCAGCTCAAGGGTGGCACCGTCAAC
TTCGACGTCATCACCGTCACCGGCACGGAGAACGTGATGATGGCGGCGGTGCTGGCCAAGGGCCGCACCCTCATGGAGAA
CTGCGCCCGCGAGCCCGAGGTCGAAGAGCTGGCCAAGGTGCTCAACAAGATGGGGGCGCGCATCGAGGGCGCGGGCACGT
CCAGCATCACCATCGAGGGCGTGGACGGGCTGAAGCCGGTGGAGCACGCCATCCTCCCCGACCGCATCGAGGCCGGCACC
CTGCTGGTGGCGGCGGCCATCTCCGGCGGCGACGTGCTGGTGAAGCGCGTGGTGCCCGAGCACATGGACGCGCTGGTGGA
GAAGCTGCGCGAGGCCGGGTGCACGATTACCACCGAGGGCAGCGGCCTGCGCTGCAAGGCGCCCCAGCGGCTGGACGCGG
TGAACATCACCACCACGGAGCATCCGGGGTTCCCCACGGACATGCAGGCCCAGCTGATGGCCCTCATGTCGGTCAGTCAG
GGGACGTCCGTCATCAGCGAGAACATCTTCGAGAACCGCTTCATGCACGTGCCGGAGCTGCACCGGCTGGGCGCGGACAT
CACCATCCAGGGGCCCACCGCGGTGGTGAAGGGTGTGAAGGGCCTGAGCGGCGCGCCCGTCATGGCAACGGACTTGAGGG
CGAGTGCGTCACTCATCCTGGCCGGGCTGCGAGCGGAGGGCCGCACCGACGTCAGTCGCGTCTACCACCTGGACCGGGGC
TATGAGCGCCTGGAGCGCAAGTTGAGCGCCCTGGGTGCGGACATCCGCCGCGAGAAGGCGTAG

Upstream 100 bases:

>100_bases
CGGACGCGCGGGTGGAGAAGGACCTGGAGCGGCGGGAACGGATGGCATTTGGGACACAGCCCGTGGCCAGCGAGCCACAG
GGCTGAAGACGCAGGGAACC

Downstream 100 bases:

>100_bases
GGCTGAGGGGCCGGGGGGCGACGGGACGGCGCGTTGCCAACAGAAGGCACAAGGCGGGTTGCATCCGAAATTTCGCGCGA
CCTATCATTCTCCCATCGAC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDKIVIKGGQALHGEVQASGAKNAALPILASALLADGTSTYRNVPALADVATMLKVLRTMGCDAERDSETTDVCRVGVNG
HITPEAPYDLVKTMRASVLVLGPLVARFGRARVSMPGGCAIGARPIDQHLKGLKALGADIHLTEGYVEATAKQLKGGTVN
FDVITVTGTENVMMAAVLAKGRTLMENCAREPEVEELAKVLNKMGARIEGAGTSSITIEGVDGLKPVEHAILPDRIEAGT
LLVAAAISGGDVLVKRVVPEHMDALVEKLREAGCTITTEGSGLRCKAPQRLDAVNITTTEHPGFPTDMQAQLMALMSVSQ
GTSVISENIFENRFMHVPELHRLGADITIQGPTAVVKGVKGLSGAPVMATDLRASASLILAGLRAEGRTDVSRVYHLDRG
YERLERKLSALGADIRREKA

Sequences:

>Translated_420_residues
MDKIVIKGGQALHGEVQASGAKNAALPILASALLADGTSTYRNVPALADVATMLKVLRTMGCDAERDSETTDVCRVGVNG
HITPEAPYDLVKTMRASVLVLGPLVARFGRARVSMPGGCAIGARPIDQHLKGLKALGADIHLTEGYVEATAKQLKGGTVN
FDVITVTGTENVMMAAVLAKGRTLMENCAREPEVEELAKVLNKMGARIEGAGTSSITIEGVDGLKPVEHAILPDRIEAGT
LLVAAAISGGDVLVKRVVPEHMDALVEKLREAGCTITTEGSGLRCKAPQRLDAVNITTTEHPGFPTDMQAQLMALMSVSQ
GTSVISENIFENRFMHVPELHRLGADITIQGPTAVVKGVKGLSGAPVMATDLRASASLILAGLRAEGRTDVSRVYHLDRG
YERLERKLSALGADIRREKA
>Mature_420_residues
MDKIVIKGGQALHGEVQASGAKNAALPILASALLADGTSTYRNVPALADVATMLKVLRTMGCDAERDSETTDVCRVGVNG
HITPEAPYDLVKTMRASVLVLGPLVARFGRARVSMPGGCAIGARPIDQHLKGLKALGADIHLTEGYVEATAKQLKGGTVN
FDVITVTGTENVMMAAVLAKGRTLMENCAREPEVEELAKVLNKMGARIEGAGTSSITIEGVDGLKPVEHAILPDRIEAGT
LLVAAAISGGDVLVKRVVPEHMDALVEKLREAGCTITTEGSGLRCKAPQRLDAVNITTTEHPGFPTDMQAQLMALMSVSQ
GTSVISENIFENRFMHVPELHRLGADITIQGPTAVVKGVKGLSGAPVMATDLRASASLILAGLRAEGRTDVSRVYHLDRG
YERLERKLSALGADIRREKA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=422, Percent_Identity=53.5545023696682, Blast_Score=412, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_MYXXD (Q1D2Q7)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633066.1
- ProteinModelPortal:   Q1D2Q7
- SMR:   Q1D2Q7
- STRING:   Q1D2Q7
- GeneID:   4105660
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_4909
- TIGR:   MXAN_4909
- eggNOG:   COG0766
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- PhylomeDB:   Q1D2Q7
- ProtClustDB:   CLSK2778173
- BioCyc:   MXAN246197:MXAN_4909-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44373; Mature: 44373

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: ACT_SITE 119-119

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKIVIKGGQALHGEVQASGAKNAALPILASALLADGTSTYRNVPALADVATMLKVLRTM
CCCEEEECCCEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHH
GCDAERDSETTDVCRVGVNGHITPEAPYDLVKTMRASVLVLGPLVARFGRARVSMPGGCA
CCCCCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
IGARPIDQHLKGLKALGADIHLTEGYVEATAKQLKGGTVNFDVITVTGTENVMMAAVLAK
CCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHC
GRTLMENCAREPEVEELAKVLNKMGARIEGAGTSSITIEGVDGLKPVEHAILPDRIEAGT
CHHHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCE
LLVAAAISGGDVLVKRVVPEHMDALVEKLREAGCTITTEGSGLRCKAPQRLDAVNITTTE
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCCCCEEEEEECC
HPGFPTDMQAQLMALMSVSQGTSVISENIFENRFMHVPELHRLGADITIQGPTAVVKGVK
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCHHHHHHCC
GLSGAPVMATDLRASASLILAGLRAEGRTDVSRVYHLDRGYERLERKLSALGADIRREKA
CCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCC
>Mature Secondary Structure
MDKIVIKGGQALHGEVQASGAKNAALPILASALLADGTSTYRNVPALADVATMLKVLRTM
CCCEEEECCCEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHH
GCDAERDSETTDVCRVGVNGHITPEAPYDLVKTMRASVLVLGPLVARFGRARVSMPGGCA
CCCCCCCCCCHHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCC
IGARPIDQHLKGLKALGADIHLTEGYVEATAKQLKGGTVNFDVITVTGTENVMMAAVLAK
CCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHCCCEEEEEEEEEECCCHHHHHHHHHC
GRTLMENCAREPEVEELAKVLNKMGARIEGAGTSSITIEGVDGLKPVEHAILPDRIEAGT
CHHHHHHHCCCCCHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCHHHHHCCCCCCCCCE
LLVAAAISGGDVLVKRVVPEHMDALVEKLREAGCTITTEGSGLRCKAPQRLDAVNITTTE
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECCCCCCCEEEEEECC
HPGFPTDMQAQLMALMSVSQGTSVISENIFENRFMHVPELHRLGADITIQGPTAVVKGVK
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHCCCCEEECCCHHHHHHCC
GLSGAPVMATDLRASASLILAGLRAEGRTDVSRVYHLDRGYERLERKLSALGADIRREKA
CCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA