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The map label for this gene is murG

Identifier: 108761678

GI number: 108761678

Start: 6966474

End: 6967625

Strand: Reverse

Name: murG

Synonym: MXAN_5604

Alternate gene names: 108761678

Gene position: 6967625-6966474 (Counterclockwise)

Preceding gene: 108761950

Following gene: 108759161

Centisome position: 76.23

GC content: 66.41

Gene sequence:

>1152_bases
ATGATGAAGGTGCTCATCGCGGGTGGGGGCACGGGCGGACATCTCTTTCCGGGCATCGCCCTGGCGGAAGAGGTGGTGAC
ACGGCATCACCGCAACGAGGTTGTCTTCGTGGGCACCGAGCGCGGCATCGAGTCGCGCGTGGTGCCGAAGGAAGGTTATC
CGCTGGAGCTGGTGAAGGTGCAGGGCCTCAAGGGCAAGGGCTTCTTGTCCCTGCTCAAGGCGCTCTTCGCGCTGCCGCTG
GCCTTCATCGAGTCCTTTCGCATCCTCGCCCGGCAGAAGCCGGATGTGGTGGTGGGCGTGGGTGGCTACGCCAGCGGGCC
GGTGGTGATGGCCGCGTGGCTGATGGGCATCCCCACCGCCATCCAGGAGCAGAACGCGCTGCCCGGCTTCACCAACAAGG
TGCTGGGCCGCATCGTGCGCGTGGTGTTCATCGCCTTCGAGGAAGCGCGCGCCTTCTTCCCGGAGAAGAAGGTCCAGCTC
ATCGGCAACCCCATCCGCCGCAAGCTGATGGACAACTACCTGCGCAGCCACGTCGCGCACGAGCGCTTCTCCGTGCTCGT
TTTCGGCGGCAGCCTGGGTGCGCGGGGCATCAACCAGCGGATGACGGAAGCGCTGGATTCGCTGGGCGACCTGAAGGACA
GCCTGCACTTCGTCCACCAGACGGGGAAGAACGACCTGGAGTCGGTGCGCAAGGGCTACGCGGACAAGGGCTTCCAGGCG
GAGGTGGTCGAGTTCATCGACGACATGTCCAGCGCCTATGCCCGCGCGGACCTCGTCGTCTGTCGCGCCGGCGCGACGAC
CCTCGCGGAGCTGACCGTCTGTAAGAAGGCCAGCATCCTGATTCCCTTCCCGCACGCCACGGACGACCACCAGGCCGTCA
ACGCGCGGGCGTTGGTGGATGCTGGCGCGGCGCTGATGTTTCGCGAGTCGGAGCTCACCGGGGAAAAGCTGGCGCAGACG
GTGCGTGAGCTGAAGAGCCACCCGGAGCGCCTCAAGAGCATGGAGAAGAAGGCGGGCCTGTTGGGCCGTCCCGAGGCCGC
CAAGGAACTGGCGGACGTGTGCGTGGACCTGATGGTCCAGACGTGGGGCCCCAACGGCCGCGAGCGTACCCCCATCGAAG
CCGAGAAGAAGGCCCCCAGGAGCAATTCGTGA

Upstream 100 bases:

>100_bases
TGTTGATGGGTGCGGCTGGAGTGCTGTTGTCGTTGAGCGCGAACACCCAGGGGGTCGCGAGGCCCAGCCGGGTGGGAACC
GACATGCGGGAGGTGGCGGC

Downstream 100 bases:

>100_bases
CACGTAACAAGCCCCCCAGCCTCTTCAAGACGCGCCATGCGGCGCAGGTCCACTTCGTGGGGCTCGGTGGTATCGGCATG
AGCGGCATCGCCGAGGTGCT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MMKVLIAGGGTGGHLFPGIALAEEVVTRHHRNEVVFVGTERGIESRVVPKEGYPLELVKVQGLKGKGFLSLLKALFALPL
AFIESFRILARQKPDVVVGVGGYASGPVVMAAWLMGIPTAIQEQNALPGFTNKVLGRIVRVVFIAFEEARAFFPEKKVQL
IGNPIRRKLMDNYLRSHVAHERFSVLVFGGSLGARGINQRMTEALDSLGDLKDSLHFVHQTGKNDLESVRKGYADKGFQA
EVVEFIDDMSSAYARADLVVCRAGATTLAELTVCKKASILIPFPHATDDHQAVNARALVDAGAALMFRESELTGEKLAQT
VRELKSHPERLKSMEKKAGLLGRPEAAKELADVCVDLMVQTWGPNGRERTPIEAEKKAPRSNS

Sequences:

>Translated_383_residues
MMKVLIAGGGTGGHLFPGIALAEEVVTRHHRNEVVFVGTERGIESRVVPKEGYPLELVKVQGLKGKGFLSLLKALFALPL
AFIESFRILARQKPDVVVGVGGYASGPVVMAAWLMGIPTAIQEQNALPGFTNKVLGRIVRVVFIAFEEARAFFPEKKVQL
IGNPIRRKLMDNYLRSHVAHERFSVLVFGGSLGARGINQRMTEALDSLGDLKDSLHFVHQTGKNDLESVRKGYADKGFQA
EVVEFIDDMSSAYARADLVVCRAGATTLAELTVCKKASILIPFPHATDDHQAVNARALVDAGAALMFRESELTGEKLAQT
VRELKSHPERLKSMEKKAGLLGRPEAAKELADVCVDLMVQTWGPNGRERTPIEAEKKAPRSNS
>Mature_383_residues
MMKVLIAGGGTGGHLFPGIALAEEVVTRHHRNEVVFVGTERGIESRVVPKEGYPLELVKVQGLKGKGFLSLLKALFALPL
AFIESFRILARQKPDVVVGVGGYASGPVVMAAWLMGIPTAIQEQNALPGFTNKVLGRIVRVVFIAFEEARAFFPEKKVQL
IGNPIRRKLMDNYLRSHVAHERFSVLVFGGSLGARGINQRMTEALDSLGDLKDSLHFVHQTGKNDLESVRKGYADKGFQA
EVVEFIDDMSSAYARADLVVCRAGATTLAELTVCKKASILIPFPHATDDHQAVNARALVDAGAALMFRESELTGEKLAQT
VRELKSHPERLKSMEKKAGLLGRPEAAKELADVCVDLMVQTWGPNGRERTPIEAEKKAPRSNS

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=358, Percent_Identity=39.1061452513966, Blast_Score=229, Evalue=2e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_MYXXD (Q1D0T0)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_633743.1
- ProteinModelPortal:   Q1D0T0
- SMR:   Q1D0T0
- STRING:   Q1D0T0
- GeneID:   4104076
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_5604
- TIGR:   MXAN_5604
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q1D0T0
- ProtClustDB:   PRK00726
- BioCyc:   MXAN246197:MXAN_5604-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 41786; Mature: 41786

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKVLIAGGGTGGHLFPGIALAEEVVTRHHRNEVVFVGTERGIESRVVPKEGYPLELVKV
CEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEE
QGLKGKGFLSLLKALFALPLAFIESFRILARQKPDVVVGVGGYASGPVVMAAWLMGIPTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCHH
IQEQNALPGFTNKVLGRIVRVVFIAFEEARAFFPEKKVQLIGNPIRRKLMDNYLRSHVAH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ERFSVLVFGGSLGARGINQRMTEALDSLGDLKDSLHFVHQTGKNDLESVRKGYADKGFQA
HHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHH
EVVEFIDDMSSAYARADLVVCRAGATTLAELTVCKKASILIPFPHATDDHQAVNARALVD
HHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
AGAALMFRESELTGEKLAQTVRELKSHPERLKSMEKKAGLLGRPEAAKELADVCVDLMVQ
CCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TWGPNGRERTPIEAEKKAPRSNS
HCCCCCCCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MMKVLIAGGGTGGHLFPGIALAEEVVTRHHRNEVVFVGTERGIESRVVPKEGYPLELVKV
CEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEEEEEE
QGLKGKGFLSLLKALFALPLAFIESFRILARQKPDVVVGVGGYASGPVVMAAWLMGIPTA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHCCCHH
IQEQNALPGFTNKVLGRIVRVVFIAFEEARAFFPEKKVQLIGNPIRRKLMDNYLRSHVAH
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHH
ERFSVLVFGGSLGARGINQRMTEALDSLGDLKDSLHFVHQTGKNDLESVRKGYADKGFQA
HHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCHH
EVVEFIDDMSSAYARADLVVCRAGATTLAELTVCKKASILIPFPHATDDHQAVNARALVD
HHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHH
AGAALMFRESELTGEKLAQTVRELKSHPERLKSMEKKAGLLGRPEAAKELADVCVDLMVQ
CCHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
TWGPNGRERTPIEAEKKAPRSNS
HCCCCCCCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA