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The map label for this gene is grsT [H]

Identifier: 108761604

GI number: 108761604

Start: 4254240

End: 4254992

Strand: Reverse

Name: grsT [H]

Synonym: MXAN_3628

Alternate gene names: 108761604

Gene position: 4254992-4254240 (Counterclockwise)

Preceding gene: 108758643

Following gene: 108759990

Centisome position: 46.55

GC content: 70.92

Gene sequence:

>753_bases
ATGACGGATTGGTTGGCCTTCCACGTCCCCGCACCGGCGTCCTGGGTGCGGCTGTTCTGTCTGCCTCACGCGGGTGGCAG
CGCCTCCCTGTTCCGCACCTGGCAGGCGGAGCTGGGACAAGACATCGAGGTGTGCCCGGTGCAGCTCCCCGGTCGGGAGA
ACCGCCTGCGCGAGCCACCCCTGCGCGCGCTGCCGGACGTCATCGCGCCCCTGGTGGACGTGCTGGCCAAGCACACGGAC
AAGCCCTACGCCCTCTTCGGACACAGCATGGGCGCACTGCTCGCATACGAGCTGACGCGGGCGCTGCGCGAGCGCGGGCT
GCCGGCGCCGCTGCACCTCTTCGTCGCCAGCTACCGGGCGCCGCACACGCTCCAGGCCCACACACCGGCCACGGCCACCC
ATGACATCGACGCGTCCGAAGCCCGGCGCCTGGGTGAGTCACGCGCCGTGTCGGGCGAGATGGCGGAAGAGCTGCTGACT
TTGATGCGCGCCACCATGCTGGCGGACACCGCCGTGTGCGAGGGCTACGCGTGGAAGCCGGGCCCCATCCTGGCGTGCCC
GCTCTCCGCCTTCCGCGGCTTCGACGACTACGTGCCCGATGACGCGACGGAGGCGTGGCGCCAGCTCACCTCCGGTCCGT
TCGCCACCCAGACGTTCCTGGGGGATCACTTCTTCCTGCGACAGACGCCGCGCGGCCTGCTGCAGAACATCCGCCGGAGC
CTCACCAGGCTGCGGCCCGCATCGACTCGCTGA

Upstream 100 bases:

>100_bases
AGCAACGCGTGGTGGAGCTGTTCAGCCTGCCGCGCATGGTGGCTGCCAACCTCGCTGTGTACCAGAAGCTCGTTGGCGGA
CAGGGACGCGAGGTGCGGTC

Downstream 100 bases:

>100_bases
CCCCACTTTTCAAAGGAGCCTTCCCGATGAAGTACCTCGTCTACGTCAAGGATCGCACTTCGGGCCCCCAGCCCCAGGAC
CCCATCGCCCTCAACCGCGC

Product: non-ribosomal peptide biosynthesis thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTDWLAFHVPAPASWVRLFCLPHAGGSASLFRTWQAELGQDIEVCPVQLPGRENRLREPPLRALPDVIAPLVDVLAKHTD
KPYALFGHSMGALLAYELTRALRERGLPAPLHLFVASYRAPHTLQAHTPATATHDIDASEARRLGESRAVSGEMAEELLT
LMRATMLADTAVCEGYAWKPGPILACPLSAFRGFDDYVPDDATEAWRQLTSGPFATQTFLGDHFFLRQTPRGLLQNIRRS
LTRLRPASTR

Sequences:

>Translated_250_residues
MTDWLAFHVPAPASWVRLFCLPHAGGSASLFRTWQAELGQDIEVCPVQLPGRENRLREPPLRALPDVIAPLVDVLAKHTD
KPYALFGHSMGALLAYELTRALRERGLPAPLHLFVASYRAPHTLQAHTPATATHDIDASEARRLGESRAVSGEMAEELLT
LMRATMLADTAVCEGYAWKPGPILACPLSAFRGFDDYVPDDATEAWRQLTSGPFATQTFLGDHFFLRQTPRGLLQNIRRS
LTRLRPASTR
>Mature_249_residues
TDWLAFHVPAPASWVRLFCLPHAGGSASLFRTWQAELGQDIEVCPVQLPGRENRLREPPLRALPDVIAPLVDVLAKHTDK
PYALFGHSMGALLAYELTRALRERGLPAPLHLFVASYRAPHTLQAHTPATATHDIDASEARRLGESRAVSGEMAEELLTL
MRATMLADTAVCEGYAWKPGPILACPLSAFRGFDDYVPDDATEAWRQLTSGPFATQTFLGDHFFLRQTPRGLLQNIRRSL
TRLRPASTR

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=224, Percent_Identity=30.8035714285714, Blast_Score=100, Evalue=9e-22,
Organism=Homo sapiens, GI8922871, Length=189, Percent_Identity=31.2169312169312, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 27701; Mature: 27570

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDWLAFHVPAPASWVRLFCLPHAGGSASLFRTWQAELGQDIEVCPVQLPGRENRLREPP
CCCCEEEECCCCHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
LRALPDVIAPLVDVLAKHTDKPYALFGHSMGALLAYELTRALRERGLPAPLHLFVASYRA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
PHTLQAHTPATATHDIDASEARRLGESRAVSGEMAEELLTLMRATMLADTAVCEGYAWKP
CCEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPILACPLSAFRGFDDYVPDDATEAWRQLTSGPFATQTFLGDHFFLRQTPRGLLQNIRRS
CCEEECCHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHCCHHHHHHHHHHH
LTRLRPASTR
HHHCCCCCCC
>Mature Secondary Structure 
TDWLAFHVPAPASWVRLFCLPHAGGSASLFRTWQAELGQDIEVCPVQLPGRENRLREPP
CCCEEEECCCCHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCC
LRALPDVIAPLVDVLAKHTDKPYALFGHSMGALLAYELTRALRERGLPAPLHLFVASYRA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCC
PHTLQAHTPATATHDIDASEARRLGESRAVSGEMAEELLTLMRATMLADTAVCEGYAWKP
CCEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
GPILACPLSAFRGFDDYVPDDATEAWRQLTSGPFATQTFLGDHFFLRQTPRGLLQNIRRS
CCEEECCHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHCCHHHHHCCHHHHHHHHHHH
LTRLRPASTR
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]