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The map label for this gene is glyA [H]

Identifier: 108761101

GI number: 108761101

Start: 5742028

End: 5743398

Strand: Direct

Name: glyA [H]

Synonym: MXAN_4593

Alternate gene names: 108761101

Gene position: 5742028-5743398 (Clockwise)

Preceding gene: 108760510

Following gene: 108758230

Centisome position: 62.82

GC content: 66.89

Gene sequence:

>1371_bases
ATGTCGTTAGGATTGCGCAGTGGAGGCCGGTCTCGCGGGCCACTGCCTCAAGGAGCGTCCGTGGACCTGGAACAGATCTC
AGAGATCCTGACCCGCCTCGAACAGCATGAGACACGCGCCGCGCGCACCCTGAACATGGTGCCGAGCGAGAACAGCATGT
CGGCGCTGGCCAAGCTGCCGATGCTGCTCGATCTACACCACCGCTATTTTTTCAATGATGGGGCAGAAGAGGAGCCCTGG
GAGTTCCGGGGCGTACAAGAGCTGTCCTCGCTGGAGACCGAGCTGGCGAGGCCGCTGCTGCGCGAGTTGGCCGGCGCCGA
GTTCGTCAACGTGCGCGCGCTGTCCGGGCTGAACCTGATGACCCTGACGCTGTCCGCGCTCGGAGGCCCGCCTGGCTCCA
CGGTGATGCTGCTATCCCGCGCCCAGGGCGGGCACTATGCGACCGCGAGCGTCGCCGCCCGGCTGGGATTGAAGGTCTGC
TACGCCACGGGCCCCGACGCGCACACCGTGGACGAGACACAGTTCGCAGAGACGCTGCGGGCCCACCAGCCGGGGCTCGT
CTACATCGATCAATCCAATGCGCTGTTTCCCCTGGGCGTCGAACGGCTGGCGCGGGCCGTCCAGCGAGATGCCCCGAACA
CCCTGCTCCACATCGACGCAAGTCATTGGATGGGTCTGGTGCTCGGCCGTCAGCTTCCCAATCCGCTCACGGAGGGGGCC
CACTCCTTCGGCGGCTCCACCCACAAGACCTTCCCGGGTCCGCAGAAGGCCATCTTCGCCACCAACCGGAGGGAGCTCTT
CGAGCGCTTCCGAGCAACCCAGCAGTACATGGTGAGCAGCCACCACTTCGGGGCGACGGTGAGCCTGGCGTTGGCGCTGC
TCGAGTTCAAGCACTGCCGGGGTGAGCAGTACGCCGCCCAGGTGGTGTTGAATACCCGGCGCTTCGGCGCCGCGCTCGAT
CGTCTCGGGTTGGCGCTTGACGGCAAGGAACGTGGCTTCTCGGCCGGCCATCAGCTCTGGATCCGGACGCGGGCCTCCGG
CGTGGACGCGTTCACCGCGAGCCAGCGGCTGTTCGACGCGGGCATCCGCACCAATGCCTATCCATCGCTGCCCGGCATCC
CTGAACCGGTCCTCCGGGTCGGCCTGAACGAGCCCACGTACCACGGACTCATGGCCGACGACATGGAGGAGCTCGCCGGG
CTCTTCGTCGCGGCAATCTTCCAGACGCAGCCGACGGAGCAGATCGCCGGGCGTGTGGCGGCGCTGCGCGCGCGCTACCG
GTTCCCCTACCGCTTCCCATCCGACGACCCAAAGCTGCTCGAACAAGCGATGCGACTGGTGCGTCTGGCGTTGACACAGC
CCGTGGAGTGA

Upstream 100 bases:

>100_bases
TTGATCCGGAAAACTCCTGCGAGAGTCCAGGATTGTGCCCATCATGGGAAAGTCATGCAAGTGCCGCTCGCAGCCCCACA
AGCGAACCCGCGCCTGACAC

Downstream 100 bases:

>100_bases
GGCCGCGGCATGGCTTCCAGGGAACATGGACTGTCCGCGGAAGACGGGACAAGCTCGGACCATGAACCTGGTCCCCTTCG
CGAACGAGCACCTGGAAGCG

Product: hypothetical protein

Products: NA

Alternate protein names: SHMT; Serine methylase [H]

Number of amino acids: Translated: 456; Mature: 455

Protein sequence:

>456_residues
MSLGLRSGGRSRGPLPQGASVDLEQISEILTRLEQHETRAARTLNMVPSENSMSALAKLPMLLDLHHRYFFNDGAEEEPW
EFRGVQELSSLETELARPLLRELAGAEFVNVRALSGLNLMTLTLSALGGPPGSTVMLLSRAQGGHYATASVAARLGLKVC
YATGPDAHTVDETQFAETLRAHQPGLVYIDQSNALFPLGVERLARAVQRDAPNTLLHIDASHWMGLVLGRQLPNPLTEGA
HSFGGSTHKTFPGPQKAIFATNRRELFERFRATQQYMVSSHHFGATVSLALALLEFKHCRGEQYAAQVVLNTRRFGAALD
RLGLALDGKERGFSAGHQLWIRTRASGVDAFTASQRLFDAGIRTNAYPSLPGIPEPVLRVGLNEPTYHGLMADDMEELAG
LFVAAIFQTQPTEQIAGRVAALRARYRFPYRFPSDDPKLLEQAMRLVRLALTQPVE

Sequences:

>Translated_456_residues
MSLGLRSGGRSRGPLPQGASVDLEQISEILTRLEQHETRAARTLNMVPSENSMSALAKLPMLLDLHHRYFFNDGAEEEPW
EFRGVQELSSLETELARPLLRELAGAEFVNVRALSGLNLMTLTLSALGGPPGSTVMLLSRAQGGHYATASVAARLGLKVC
YATGPDAHTVDETQFAETLRAHQPGLVYIDQSNALFPLGVERLARAVQRDAPNTLLHIDASHWMGLVLGRQLPNPLTEGA
HSFGGSTHKTFPGPQKAIFATNRRELFERFRATQQYMVSSHHFGATVSLALALLEFKHCRGEQYAAQVVLNTRRFGAALD
RLGLALDGKERGFSAGHQLWIRTRASGVDAFTASQRLFDAGIRTNAYPSLPGIPEPVLRVGLNEPTYHGLMADDMEELAG
LFVAAIFQTQPTEQIAGRVAALRARYRFPYRFPSDDPKLLEQAMRLVRLALTQPVE
>Mature_455_residues
SLGLRSGGRSRGPLPQGASVDLEQISEILTRLEQHETRAARTLNMVPSENSMSALAKLPMLLDLHHRYFFNDGAEEEPWE
FRGVQELSSLETELARPLLRELAGAEFVNVRALSGLNLMTLTLSALGGPPGSTVMLLSRAQGGHYATASVAARLGLKVCY
ATGPDAHTVDETQFAETLRAHQPGLVYIDQSNALFPLGVERLARAVQRDAPNTLLHIDASHWMGLVLGRQLPNPLTEGAH
SFGGSTHKTFPGPQKAIFATNRRELFERFRATQQYMVSSHHFGATVSLALALLEFKHCRGEQYAAQVVLNTRRFGAALDR
LGLALDGKERGFSAGHQLWIRTRASGVDAFTASQRLFDAGIRTNAYPSLPGIPEPVLRVGLNEPTYHGLMADDMEELAGL
FVAAIFQTQPTEQIAGRVAALRARYRFPYRFPSDDPKLLEQAMRLVRLALTQPVE

Specific function: Interconversion of serine and glycine [H]

COG id: COG0112

COG function: function code E; Glycine/serine hydroxymethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SHMT family [H]

Homologues:

None

Paralogues:

None

Copy number: 3180 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 12,000 Molecules/Cell In: Glucose minimal

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR001085
- InterPro:   IPR019798 [H]

Pfam domain/function: PF00464 SHMT [H]

EC number: =2.1.2.1 [H]

Molecular weight: Translated: 50079; Mature: 49948

Theoretical pI: Translated: 7.88; Mature: 7.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLGLRSGGRSRGPLPQGASVDLEQISEILTRLEQHETRAARTLNMVPSENSMSALAKLP
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MLLDLHHRYFFNDGAEEEPWEFRGVQELSSLETELARPLLRELAGAEFVNVRALSGLNLM
HHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCHHH
TLTLSALGGPPGSTVMLLSRAQGGHYATASVAARLGLKVCYATGPDAHTVDETQFAETLR
HHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHH
AHQPGLVYIDQSNALFPLGVERLARAVQRDAPNTLLHIDASHWMGLVLGRQLPNPLTEGA
HCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHH
HSFGGSTHKTFPGPQKAIFATNRRELFERFRATQQYMVSSHHFGATVSLALALLEFKHCR
HHCCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
GEQYAAQVVLNTRRFGAALDRLGLALDGKERGFSAGHQLWIRTRASGVDAFTASQRLFDA
CHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
GIRTNAYPSLPGIPEPVLRVGLNEPTYHGLMADDMEELAGLFVAAIFQTQPTEQIAGRVA
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALRARYRFPYRFPSDDPKLLEQAMRLVRLALTQPVE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLGLRSGGRSRGPLPQGASVDLEQISEILTRLEQHETRAARTLNMVPSENSMSALAKLP
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
MLLDLHHRYFFNDGAEEEPWEFRGVQELSSLETELARPLLRELAGAEFVNVRALSGLNLM
HHHHHHHHHHCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCHHH
TLTLSALGGPPGSTVMLLSRAQGGHYATASVAARLGLKVCYATGPDAHTVDETQFAETLR
HHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHCEEEEEECCCCCCCCCHHHHHHHHH
AHQPGLVYIDQSNALFPLGVERLARAVQRDAPNTLLHIDASHWMGLVLGRQLPNPLTEGA
HCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHCCCCHHHHHH
HSFGGSTHKTFPGPQKAIFATNRRELFERFRATQQYMVSSHHFGATVSLALALLEFKHCR
HHCCCCCCCCCCCCCHHEEECCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHC
GEQYAAQVVLNTRRFGAALDRLGLALDGKERGFSAGHQLWIRTRASGVDAFTASQRLFDA
CHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
GIRTNAYPSLPGIPEPVLRVGLNEPTYHGLMADDMEELAGLFVAAIFQTQPTEQIAGRVA
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ALRARYRFPYRFPSDDPKLLEQAMRLVRLALTQPVE
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA