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The map label for this gene is capA [H]

Identifier: 108760803

GI number: 108760803

Start: 6138845

End: 6140062

Strand: Direct

Name: capA [H]

Synonym: MXAN_4905

Alternate gene names: 108760803

Gene position: 6138845-6140062 (Clockwise)

Preceding gene: 108760280

Following gene: 108759492

Centisome position: 67.17

GC content: 71.59

Gene sequence:

>1218_bases
ATGCGCCACGTCGCCCTGCTGCTGCTCATGTTGTCCGCCTGTCACCCCCGCACCATCCCCCCGCCGGAGCCGCTGCCGCC
GGAGGAGCCCGCCGGACAGTCCCCCGCCCCCGGGGATGCGGGCCAGGCGCCCGCCCCTCCCATCGGGGCGCCAGCGGCCG
AGCCCCCCGCCCGTTCCGTGTCCATCATCGTGGGCGGCGACGTGACGCTGGGCCACAACTACCAGACACACTACGACGCG
GAGACCGCCAAGGGCCGCCCCCAGGACGCCCTGCTGGCCTACGGGTTCCAGGAGGTGAAGCCCCTGACGGACGCCGCCGA
CCTGTTCGTCGTCAACCTGGAGTGCCCCTTCACCGAGCGCGGTGAGAAGCTGCCCAAGAACTTCAACTTCCGCGCGAAGC
CGGAGCTGGTGGGCATCCTCACCGCCGGCGGCGTGGACGTGGTGAGCCTGGCCAACAACCACCTGATGGACTACGGCGCC
CAGGGCCTGCTCGACACGCTGGACACCCTGGACGCGGCGCACATCCCCTACTTCGGCGCGGGCCGGAACCTGGCGGAGGC
CCGGCGCCCGGCCATCGTCACCGTGGGCGGCCAGCGGGTCGCGCTGCTGGGCTACTTCTTCCTGGGCACGCGCAACATCG
AACCGCCCGGGGTCTACGCCACGGAGACGACCCCTGGGGTCGCTGGCCACTTCTCCGACGAGGCCGTCATGGAGCAGATG
CTCCGGGAGGACATCGCCGCGGCCCGGGCCCAGGCGGACATCGTCCTGCCCTACTTCCACTGGGGACGCGAAGGCACCTA
CACCCCGGAGCCCTACCAGGTCCGCCTGGCCCACGTCGCCATCGACGCGGGCGCCGCGGGTGTGCTGGGCGCCCACCCGC
ACGTCCTCCAGGCCATGGAGCTGTACCAGGGCAGACCGGTCGTCTACTCGCTGGGGAACTTCGTCTTCGGGGGGAACTGG
AACCCTCGCGACAAGCGCGGCGCCCTGTGGAAGGGCCACTTCGGGCCCGACGGCGGCTACCTGTCCAGCGAGATTCTGCC
CTTGAGGACCGACCGCTTCCCGGAGCTGCCCTTCCAGCCGGTGCCCGTCACGGGCGAGGCGGCGGAGGCGGTGCTGCGGC
TCCTGGCGGAGTCTTCAGAAGGCGTGGAGCGGATGCTGCCCGAATTGGAACCGTGGGCACGTCCGCCTCCCTCCCCCGAA
GTCCGAGGGAGGGAGTAG

Upstream 100 bases:

>100_bases
TCGTCGGAGAGAGCGATGTTGTCCTTTTCGCGGGCCATGAGCGCGCGGGCAATCTACGCGCCGCGCTCCAAGAGGTGCAA
GGTAGAGTTTCCCCTCGCCC

Downstream 100 bases:

>100_bases
CCAACGCACTAGACCTTGTTGTTGGACTGGCCCTTCTTGGCGCGGCTGCGGCGGCGCTTCAGCTGGGCCTTCCGGCCCTT
GGCGCGGTTGGCGACCTTCT

Product: putative polyglutamate synthase CapA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MRHVALLLLMLSACHPRTIPPPEPLPPEEPAGQSPAPGDAGQAPAPPIGAPAAEPPARSVSIIVGGDVTLGHNYQTHYDA
ETAKGRPQDALLAYGFQEVKPLTDAADLFVVNLECPFTERGEKLPKNFNFRAKPELVGILTAGGVDVVSLANNHLMDYGA
QGLLDTLDTLDAAHIPYFGAGRNLAEARRPAIVTVGGQRVALLGYFFLGTRNIEPPGVYATETTPGVAGHFSDEAVMEQM
LREDIAAARAQADIVLPYFHWGREGTYTPEPYQVRLAHVAIDAGAAGVLGAHPHVLQAMELYQGRPVVYSLGNFVFGGNW
NPRDKRGALWKGHFGPDGGYLSSEILPLRTDRFPELPFQPVPVTGEAAEAVLRLLAESSEGVERMLPELEPWARPPPSPE
VRGRE

Sequences:

>Translated_405_residues
MRHVALLLLMLSACHPRTIPPPEPLPPEEPAGQSPAPGDAGQAPAPPIGAPAAEPPARSVSIIVGGDVTLGHNYQTHYDA
ETAKGRPQDALLAYGFQEVKPLTDAADLFVVNLECPFTERGEKLPKNFNFRAKPELVGILTAGGVDVVSLANNHLMDYGA
QGLLDTLDTLDAAHIPYFGAGRNLAEARRPAIVTVGGQRVALLGYFFLGTRNIEPPGVYATETTPGVAGHFSDEAVMEQM
LREDIAAARAQADIVLPYFHWGREGTYTPEPYQVRLAHVAIDAGAAGVLGAHPHVLQAMELYQGRPVVYSLGNFVFGGNW
NPRDKRGALWKGHFGPDGGYLSSEILPLRTDRFPELPFQPVPVTGEAAEAVLRLLAESSEGVERMLPELEPWARPPPSPE
VRGRE
>Mature_405_residues
MRHVALLLLMLSACHPRTIPPPEPLPPEEPAGQSPAPGDAGQAPAPPIGAPAAEPPARSVSIIVGGDVTLGHNYQTHYDA
ETAKGRPQDALLAYGFQEVKPLTDAADLFVVNLECPFTERGEKLPKNFNFRAKPELVGILTAGGVDVVSLANNHLMDYGA
QGLLDTLDTLDAAHIPYFGAGRNLAEARRPAIVTVGGQRVALLGYFFLGTRNIEPPGVYATETTPGVAGHFSDEAVMEQM
LREDIAAARAQADIVLPYFHWGREGTYTPEPYQVRLAHVAIDAGAAGVLGAHPHVLQAMELYQGRPVVYSLGNFVFGGNW
NPRDKRGALWKGHFGPDGGYLSSEILPLRTDRFPELPFQPVPVTGEAAEAVLRLLAESSEGVERMLPELEPWARPPPSPE
VRGRE

Specific function: Essential for the synthesis of the polyglutamate capsule of B.anthracis which is one of the principal virulence factors during anthrax infection. May form a polyglutamyl synthetase complex together with proteins CapB and CapC [H]

COG id: COG2843

COG function: function code M; Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CapA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019079 [H]

Pfam domain/function: PF09587 PGA_cap [H]

EC number: NA

Molecular weight: Translated: 43575; Mature: 43575

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHVALLLLMLSACHPRTIPPPEPLPPEEPAGQSPAPGDAGQAPAPPIGAPAAEPPARSV
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
SIIVGGDVTLGHNYQTHYDAETAKGRPQDALLAYGFQEVKPLTDAADLFVVNLECPFTER
EEEECCCEEECCCCCCCCCCHHCCCCCHHHHHHHCHHHHCCCCCCCEEEEEEEECCCHHH
GEKLPKNFNFRAKPELVGILTAGGVDVVSLANNHLMDYGAQGLLDTLDTLDAAHIPYFGA
HHHCCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
GRNLAEARRPAIVTVGGQRVALLGYFFLGTRNIEPPGVYATETTPGVAGHFSDEAVMEQM
CCCHHHHCCCEEEEECCCEEEEEEEHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHH
LREDIAAARAQADIVLPYFHWGREGTYTPEPYQVRLAHVAIDAGAAGVLGAHPHVLQAME
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHH
LYQGRPVVYSLGNFVFGGNWNPRDKRGALWKGHFGPDGGYLSSEILPLRTDRFPELPFQP
HHCCCCEEEECCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCEECCCCCCCCCCCCC
VPVTGEAAEAVLRLLAESSEGVERMLPELEPWARPPPSPEVRGRE
CCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRHVALLLLMLSACHPRTIPPPEPLPPEEPAGQSPAPGDAGQAPAPPIGAPAAEPPARSV
CHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEE
SIIVGGDVTLGHNYQTHYDAETAKGRPQDALLAYGFQEVKPLTDAADLFVVNLECPFTER
EEEECCCEEECCCCCCCCCCHHCCCCCHHHHHHHCHHHHCCCCCCCEEEEEEEECCCHHH
GEKLPKNFNFRAKPELVGILTAGGVDVVSLANNHLMDYGAQGLLDTLDTLDAAHIPYFGA
HHHCCCCCCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
GRNLAEARRPAIVTVGGQRVALLGYFFLGTRNIEPPGVYATETTPGVAGHFSDEAVMEQM
CCCHHHHCCCEEEEECCCEEEEEEEHHHCCCCCCCCCEEEECCCCCCCCCCCHHHHHHHH
LREDIAAARAQADIVLPYFHWGREGTYTPEPYQVRLAHVAIDAGAAGVLGAHPHVLQAME
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHH
LYQGRPVVYSLGNFVFGGNWNPRDKRGALWKGHFGPDGGYLSSEILPLRTDRFPELPFQP
HHCCCCEEEECCCEEECCCCCCCCCCCCEEECCCCCCCCCCCCCCEECCCCCCCCCCCCC
VPVTGEAAEAVLRLLAESSEGVERMLPELEPWARPPPSPEVRGRE
CCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2536679; 10475962; 12004073 [H]