Click here to switch to the map view.

The map label for this gene is iap [C]

Identifier: 108759753

GI number: 108759753

Start: 5760474

End: 5762855

Strand: Direct

Name: iap [C]

Synonym: MXAN_4599

Alternate gene names: 108759753

Gene position: 5760474-5762855 (Clockwise)

Preceding gene: 108760891

Following gene: 108757382

Centisome position: 63.03

GC content: 71.28

Gene sequence:

>2382_bases
GTGGGCACGGCCGCCGCGGCGGTGGCGCCTCTCGCACGGTACGACGTGGCCCCTCCATCCCCCTCCTCGTGGTACCGCGC
GCTTCGGCCCTGGCTGCTCGGATTGGGGCTCACCCTGGTGGTCGTCGCGATCCAGGCCGAAGCGAGCCGGACACCCAGTC
CCCGCACCGCGGACGCGCCTTCCACCGAGTTCTCCGAAGAGCGTGCCCAGCGCGTCATGCGGCACCTGGCAGATGGCATC
GGTCGGCGCATCCCCGGCACCCCCGCCCACCGGGAGGCCGCCACCTACCTGGCCAGCGTGCTGCGCGAGCTTCCGCGCCT
CGAGGTCGAGATTCAGGAGGCGGAGGGGCACTATCTCGATGACGACACCCTCGTCGCCTACACCGTCCGGAACGTGGTGG
CCCGCTTGCCGGGACGCAGGCCGGACGCGGTGCTCCTCTCGGCCCATTACGACACCTCTCCTGAGGGCGCCGGAGCGGCG
GACGACGCGCTCGGAATCGCCGCGATGGTTGAGGTCGCGCGCGCACTCGCGAACGGACCGGAGCTCGAGAACACGGTCCT
CTTCAACCTCAATGGGGCCGAGGAGTATGGCCTGCTCGGCGCGGCCGGTTTCATGCAGCACCGGTGGGCGAGCCAGGTCC
GCACCTTCCTGAACCTCGAAGCCACTGGGCTGGGCGGCCGGGCCATCCTCTTCCAGGCCGGGCCGGACGCATCCTGGCTC
CTGGAGGCCTATGCCCGGGCCGTGCCCCAACCGTTCGGCGACGTGCTGGGCCAGGACCTCTTCCAGTATCGACTGGTTCC
GGCGGGCACCGACGGCCACGTGTACCGCAGCGCGGGCATCTCCGGATTGGATCTCGCCCTCTTCCGGGACGGCTATGCGG
TGCACTCCCCGTTGGATCGACCCGAGCGGGTAGAACCCGGAAGCCTTCAGCACATGGGCGAGAGCGCGCTGGCAGTGACA
CGCGAGCTCGCCACACGGCCATTCCCGGACGGGAAAGGCTCGGGCCCGTCCATCTACTACGACGTGCTGGGGCGCTGGAT
GCTCCAGTACGGCGCCCACGCGGCGTGGGCATGGGCCGCGGCCGCCGCGCTGCTGGTGGCCGGCGCCACCGTCCTCGCCA
CACGGCGGAAACTCGTCCGCCTGTCCGTGGCCGCCGAGGGGCTCGGCTTCTGTACGCTTTCGCTCGCGGTGGCGCTGGTG
GTGCCGGTTGCCTTCGGCTTCCTGCCCCACTACGCATTCGAACGCCCACATGGCTGGTACGCCTCGCCGTGGCTGGCCGT
CGCGACCTTCGGCACGCTCGCTGTGACGGGGGCGCTGCTCCCCCGCGCGCTGTGGGCGCAAAGGCTGGCTGCCCGGGGCG
TGGCTCCCCAGGAGCGAGTGTTCACGGCCTGGCTCGGAGGGCTCTGGCTGTGGGTGCTGACACTTGGCGCGTTGCAGCTC
CTGGGGCTTGGCACCGCCTACCTGGCGCTGTGGTGGACCGTGGGCGGCGCGCTCGGGCTCATCGCCGCCACCTTCCTCGC
CTCGCCTCGCGCTCGGATGATGGCCCTGTATGCGAGCTGGGTGCCGGGCTTGCTGCTGACCGTGCAGATGGGGCGCTCCC
TGCTGGAGCTCTTCGTCCCGGTGGCGGGCCACCTTCGGCTGGGGGTACCACTCGATCCACTCGTGGCCCTGCTGGCGGCG
CTGCCGGTGGCCATGGCGTCCGTGCTCGGCCTTGCCCCCGTCCAGGAGCAGTCTCGCTTCGGCCCATCGGCCGCGGCCTT
CGCCACGGCGAGCGTGGCCTTCCTGGCCGCGCTGCTCCTGCGCTTCCCGTACACACACGAACGGCCCAAGCGGCTCTGGC
TGGAGCACCGCCTTCAAGAGGGCCGCAGTGAGCTGCAGTACTCGAGCTGGGACTTTCCCGATCCGCGCGCCGCGCTCTCC
GGGCAGCCCGGGCCCCTCCAGACGGCCGCGCGGATGCCGGGCTTTCGCGGTGGTTACACCGCGCCAGTGCCGCCCGCGAA
CCTGCCTGCACCCCAGGTCGACGTGCTCGAATCACAGGACGACGAAACCACCGCGCTCCGAACCGTGCGGCTGCGCCTCC
AATTGGGCGCGGCATACCTCGGCCGGGTGCGGATTCCGCGGGCTGCCCTCGTGGGATGGTCGCTCCCGGCCCCCCTCCCG
CCGCTGGCGCCCGAGGACTCGGTCTATGTCCTCGACGTGCTCGCACCGCCAGGAGGGCACTACGAGGTCTCGCTGCGTCT
GAGAGGCCAGGAGGAGGTGCCGGTGGACGTACAAGCCTTCTTCGCGGAATGGACGCCGCCGCTCGAAGAGGCGCGTTCGC
GGCTCCCCGCGTGGACGACAGCGAACCTGCGCGTCTCCACCTACGCCACCATCCGGCTCTGA

Upstream 100 bases:

>100_bases
GAAGTAGCGCCGGGTGGTGTACCTCTTCCGGAGGACTCGCCCTCCGGAACGCGTTGCCGGAAGCATCCTTTCCGGTGGCG
CGGTGAACTCTTAAACTCGC

Downstream 100 bases:

>100_bases
CCCGCCCGGCTTACGCCTTCACCTGGACGGGCGGCGGGGCCTTGTCACCCGCCCGAGGAGGCATGGGATGGGGCTTCGGC
GCATCAGCCCTGGCGCCGCG

Product: M28 family peptidase

Products: NA

Alternate protein names: Peptidase; M28 Family Peptidase; Aminopeptidase; Peptidase Family; Peptidase Family M

Number of amino acids: Translated: 793; Mature: 792

Protein sequence:

>793_residues
MGTAAAAVAPLARYDVAPPSPSSWYRALRPWLLGLGLTLVVVAIQAEASRTPSPRTADAPSTEFSEERAQRVMRHLADGI
GRRIPGTPAHREAATYLASVLRELPRLEVEIQEAEGHYLDDDTLVAYTVRNVVARLPGRRPDAVLLSAHYDTSPEGAGAA
DDALGIAAMVEVARALANGPELENTVLFNLNGAEEYGLLGAAGFMQHRWASQVRTFLNLEATGLGGRAILFQAGPDASWL
LEAYARAVPQPFGDVLGQDLFQYRLVPAGTDGHVYRSAGISGLDLALFRDGYAVHSPLDRPERVEPGSLQHMGESALAVT
RELATRPFPDGKGSGPSIYYDVLGRWMLQYGAHAAWAWAAAAALLVAGATVLATRRKLVRLSVAAEGLGFCTLSLAVALV
VPVAFGFLPHYAFERPHGWYASPWLAVATFGTLAVTGALLPRALWAQRLAARGVAPQERVFTAWLGGLWLWVLTLGALQL
LGLGTAYLALWWTVGGALGLIAATFLASPRARMMALYASWVPGLLLTVQMGRSLLELFVPVAGHLRLGVPLDPLVALLAA
LPVAMASVLGLAPVQEQSRFGPSAAAFATASVAFLAALLLRFPYTHERPKRLWLEHRLQEGRSELQYSSWDFPDPRAALS
GQPGPLQTAARMPGFRGGYTAPVPPANLPAPQVDVLESQDDETTALRTVRLRLQLGAAYLGRVRIPRAALVGWSLPAPLP
PLAPEDSVYVLDVLAPPGGHYEVSLRLRGQEEVPVDVQAFFAEWTPPLEEARSRLPAWTTANLRVSTYATIRL

Sequences:

>Translated_793_residues
MGTAAAAVAPLARYDVAPPSPSSWYRALRPWLLGLGLTLVVVAIQAEASRTPSPRTADAPSTEFSEERAQRVMRHLADGI
GRRIPGTPAHREAATYLASVLRELPRLEVEIQEAEGHYLDDDTLVAYTVRNVVARLPGRRPDAVLLSAHYDTSPEGAGAA
DDALGIAAMVEVARALANGPELENTVLFNLNGAEEYGLLGAAGFMQHRWASQVRTFLNLEATGLGGRAILFQAGPDASWL
LEAYARAVPQPFGDVLGQDLFQYRLVPAGTDGHVYRSAGISGLDLALFRDGYAVHSPLDRPERVEPGSLQHMGESALAVT
RELATRPFPDGKGSGPSIYYDVLGRWMLQYGAHAAWAWAAAAALLVAGATVLATRRKLVRLSVAAEGLGFCTLSLAVALV
VPVAFGFLPHYAFERPHGWYASPWLAVATFGTLAVTGALLPRALWAQRLAARGVAPQERVFTAWLGGLWLWVLTLGALQL
LGLGTAYLALWWTVGGALGLIAATFLASPRARMMALYASWVPGLLLTVQMGRSLLELFVPVAGHLRLGVPLDPLVALLAA
LPVAMASVLGLAPVQEQSRFGPSAAAFATASVAFLAALLLRFPYTHERPKRLWLEHRLQEGRSELQYSSWDFPDPRAALS
GQPGPLQTAARMPGFRGGYTAPVPPANLPAPQVDVLESQDDETTALRTVRLRLQLGAAYLGRVRIPRAALVGWSLPAPLP
PLAPEDSVYVLDVLAPPGGHYEVSLRLRGQEEVPVDVQAFFAEWTPPLEEARSRLPAWTTANLRVSTYATIRL
>Mature_792_residues
GTAAAAVAPLARYDVAPPSPSSWYRALRPWLLGLGLTLVVVAIQAEASRTPSPRTADAPSTEFSEERAQRVMRHLADGIG
RRIPGTPAHREAATYLASVLRELPRLEVEIQEAEGHYLDDDTLVAYTVRNVVARLPGRRPDAVLLSAHYDTSPEGAGAAD
DALGIAAMVEVARALANGPELENTVLFNLNGAEEYGLLGAAGFMQHRWASQVRTFLNLEATGLGGRAILFQAGPDASWLL
EAYARAVPQPFGDVLGQDLFQYRLVPAGTDGHVYRSAGISGLDLALFRDGYAVHSPLDRPERVEPGSLQHMGESALAVTR
ELATRPFPDGKGSGPSIYYDVLGRWMLQYGAHAAWAWAAAAALLVAGATVLATRRKLVRLSVAAEGLGFCTLSLAVALVV
PVAFGFLPHYAFERPHGWYASPWLAVATFGTLAVTGALLPRALWAQRLAARGVAPQERVFTAWLGGLWLWVLTLGALQLL
GLGTAYLALWWTVGGALGLIAATFLASPRARMMALYASWVPGLLLTVQMGRSLLELFVPVAGHLRLGVPLDPLVALLAAL
PVAMASVLGLAPVQEQSRFGPSAAAFATASVAFLAALLLRFPYTHERPKRLWLEHRLQEGRSELQYSSWDFPDPRAALSG
QPGPLQTAARMPGFRGGYTAPVPPANLPAPQVDVLESQDDETTALRTVRLRLQLGAAYLGRVRIPRAALVGWSLPAPLPP
LAPEDSVYVLDVLAPPGGHYEVSLRLRGQEEVPVDVQAFFAEWTPPLEEARSRLPAWTTANLRVSTYATIRL

Specific function: This Protein, Presumably An Aminopeptidase, Mediates The Conversion Of E.Coli Alkaline Phosphatase Isozyme 1, To Isozymes 2 And 3 By Removing, One By One, The Two Amino-Terminal Arginine Residues. [C]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI55749804, Length=637, Percent_Identity=27.6295133437991, Blast_Score=204, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI17531383, Length=622, Percent_Identity=28.9389067524116, Blast_Score=228, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI193204254, Length=601, Percent_Identity=29.450915141431, Blast_Score=216, Evalue=4e-56,
Organism=Saccharomyces cerevisiae, GI6319548, Length=284, Percent_Identity=29.9295774647887, Blast_Score=138, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24655610, Length=575, Percent_Identity=29.2173913043478, Blast_Score=223, Evalue=5e-58,
Organism=Drosophila melanogaster, GI45550463, Length=575, Percent_Identity=29.2173913043478, Blast_Score=222, Evalue=7e-58,
Organism=Drosophila melanogaster, GI221330185, Length=675, Percent_Identity=26.962962962963, Blast_Score=199, Evalue=7e-51,
Organism=Drosophila melanogaster, GI45550464, Length=357, Percent_Identity=33.8935574229692, Blast_Score=199, Evalue=7e-51,
Organism=Drosophila melanogaster, GI24652989, Length=669, Percent_Identity=26.7563527653214, Blast_Score=192, Evalue=8e-49,
Organism=Drosophila melanogaster, GI24655613, Length=598, Percent_Identity=25.5852842809365, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI281363746, Length=481, Percent_Identity=29.3139293139293, Blast_Score=187, Evalue=4e-47,
Organism=Drosophila melanogaster, GI28573701, Length=468, Percent_Identity=28.8461538461538, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI28573381, Length=633, Percent_Identity=26.8562401263823, Blast_Score=182, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24652993, Length=668, Percent_Identity=26.1976047904192, Blast_Score=181, Evalue=1e-45,
Organism=Drosophila melanogaster, GI28573565, Length=656, Percent_Identity=26.5243902439024, Blast_Score=178, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24655630, Length=633, Percent_Identity=24.9605055292259, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI221330187, Length=432, Percent_Identity=28.0092592592593, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28573377, Length=590, Percent_Identity=23.5593220338983, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI28573379, Length=593, Percent_Identity=23.9460370994941, Blast_Score=126, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.4.11.- [C]

Molecular weight: Translated: 85271; Mature: 85140

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: PS00758 ARGE_DAPE_CPG2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTAAAAVAPLARYDVAPPSPSSWYRALRPWLLGLGLTLVVVAIQAEASRTPSPRTADAP
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STEFSEERAQRVMRHLADGIGRRIPGTPAHREAATYLASVLRELPRLEVEIQEAEGHYLD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
DDTLVAYTVRNVVARLPGRRPDAVLLSAHYDTSPEGAGAADDALGIAAMVEVARALANGP
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ELENTVLFNLNGAEEYGLLGAAGFMQHRWASQVRTFLNLEATGLGGRAILFQAGPDASWL
CCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHH
LEAYARAVPQPFGDVLGQDLFQYRLVPAGTDGHVYRSAGISGLDLALFRDGYAVHSPLDR
HHHHHHHCCCHHHHHHHHHHHHEEEEECCCCCCEECCCCCCCCEEHHHCCCCCCCCCCCC
PERVEPGSLQHMGESALAVTRELATRPFPDGKGSGPSIYYDVLGRWMLQYGAHAAWAWAA
CCCCCCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHH
AAALLVAGATVLATRRKLVRLSVAAEGLGFCTLSLAVALVVPVAFGFLPHYAFERPHGWY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASPWLAVATFGTLAVTGALLPRALWAQRLAARGVAPQERVFTAWLGGLWLWVLTLGALQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGLGTAYLALWWTVGGALGLIAATFLASPRARMMALYASWVPGLLLTVQMGRSLLELFVP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGHLRLGVPLDPLVALLAALPVAMASVLGLAPVQEQSRFGPSAAAFATASVAFLAALLL
HHCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHH
RFPYTHERPKRLWLEHRLQEGRSELQYSSWDFPDPRAALSGQPGPLQTAARMPGFRGGYT
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHCCCCCCCCC
APVPPANLPAPQVDVLESQDDETTALRTVRLRLQLGAAYLGRVRIPRAALVGWSLPAPLP
CCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
PLAPEDSVYVLDVLAPPGGHYEVSLRLRGQEEVPVDVQAFFAEWTPPLEEARSRLPAWTT
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEEE
ANLRVSTYATIRL
CCEEEEEEEEEEC
>Mature Secondary Structure 
GTAAAAVAPLARYDVAPPSPSSWYRALRPWLLGLGLTLVVVAIQAEASRTPSPRTADAP
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
STEFSEERAQRVMRHLADGIGRRIPGTPAHREAATYLASVLRELPRLEVEIQEAEGHYLD
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
DDTLVAYTVRNVVARLPGRRPDAVLLSAHYDTSPEGAGAADDALGIAAMVEVARALANGP
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
ELENTVLFNLNGAEEYGLLGAAGFMQHRWASQVRTFLNLEATGLGGRAILFQAGPDASWL
CCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEEECCCCHHHH
LEAYARAVPQPFGDVLGQDLFQYRLVPAGTDGHVYRSAGISGLDLALFRDGYAVHSPLDR
HHHHHHHCCCHHHHHHHHHHHHEEEEECCCCCCEECCCCCCCCEEHHHCCCCCCCCCCCC
PERVEPGSLQHMGESALAVTRELATRPFPDGKGSGPSIYYDVLGRWMLQYGAHAAWAWAA
CCCCCCCCHHHHCHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHHHHHHHHCCCHHHHHHH
AAALLVAGATVLATRRKLVRLSVAAEGLGFCTLSLAVALVVPVAFGFLPHYAFERPHGWY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
ASPWLAVATFGTLAVTGALLPRALWAQRLAARGVAPQERVFTAWLGGLWLWVLTLGALQL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LGLGTAYLALWWTVGGALGLIAATFLASPRARMMALYASWVPGLLLTVQMGRSLLELFVP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGHLRLGVPLDPLVALLAALPVAMASVLGLAPVQEQSRFGPSAAAFATASVAFLAALLL
HHCCEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHH
RFPYTHERPKRLWLEHRLQEGRSELQYSSWDFPDPRAALSGQPGPLQTAARMPGFRGGYT
HCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCHHHHHCCCCCCCCC
APVPPANLPAPQVDVLESQDDETTALRTVRLRLQLGAAYLGRVRIPRAALVGWSLPAPLP
CCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCC
PLAPEDSVYVLDVLAPPGGHYEVSLRLRGQEEVPVDVQAFFAEWTPPLEEARSRLPAWTT
CCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHCCCEEE
ANLRVSTYATIRL
CCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Aminopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA