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The map label for this gene is 108759310

Identifier: 108759310

GI number: 108759310

Start: 1612559

End: 1613458

Strand: Reverse

Name: 108759310

Synonym: MXAN_1373

Alternate gene names: NA

Gene position: 1613458-1612559 (Counterclockwise)

Preceding gene: 108762079

Following gene: 108760406

Centisome position: 17.65

GC content: 70.78

Gene sequence:

>900_bases
GTGCGCGTCTTCCATTCGGACAGCTACGAAGTCCCGTTGCCTCCCGGCCACCGCTTCCCCATGGAGAAGTACCGGCTGCT
GCGCGAGGCGCTCCTGGAGCGGGGCGTGCTCACCCCGGAATCCCTCACCGAATCCACGCCCTGCCCACGCCAGGACCTCG
CGCGCGTCCACACGCCCCGCTACCTCGACGCGCTGTCCCAGGGCACCCTCACCGACGCCGAGCAACGGCGCCTCGGCTTC
CCCTGGTCCCCCGAGCTGATGCGGCGCTTCTCCGCCGCGGTGGCGGGCACCCTCGACGCCGCCCGCGCGGCGCTCCAGGA
CGGCATCGGCGGCAACCTCTCCGGCGGCACGCACCACGGCTTTCCGGACCACGGCGAGGGCTTCTGCGTCTTCAATGACA
TCGCGGTGGCCATCCGCGTGCTCCAGGCCTCGCGTGACATCCGCCGGGCCGTGGTGGTGGACCTGGACGTCCACCAGGGC
AACGGCACCGCCGCCGTCTTCACCGGCGACGACTCCGTCTTCACCTTCTCCATGCACGGAGAAAACAACTTCCCCTTCCG
CAAGCAGCCCTCCCACCTCGACGTGGGCCTGCCAGACGGCACGGGAGACGCGGCATACCTGGACGCGCTCGCCCTGCACC
TGCCCGAGGTGCTCGACAGCGCGGGCGCCTGCATCCTCTTCTTCCAGGCGGGCGTGGACCCGCTCACGGAAGACGCGCTG
GGACGGCTGTCCCTCACTCACGCCGGACTGAGAGCGCGCGACAGGCTGGTGCTCGAGGCCGCACGCCAACGGGGCATCCC
CGCGGTGCTCACCCTGGGCGGCGGCTACGCGAAACCCCTGTCCGCCACGATTGATGCGCACGTGGGCACCTATGAAGTGG
CCCGTGCGCTGTTCCGCTGA

Upstream 100 bases:

>100_bases
CGAAACGAATGACTTCGCCCCTGGGTCTACGCCCCCGGTCGATTTCTCACACGCGCCGCCGGTTGCACCCGCCCGGCCCT
GGAGTTAGGGCACCTTCCGC

Downstream 100 bases:

>100_bases
GCCCGCCTGCTCTGGAGCGGCTTGCCCGGGTGCCACGGTGGACGGATGCTGGCACGCACCAGGAGATTCAAGAACATGAC
CCCATCCCTCCGCCGGTCCC

Product: histone deacetylase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRVFHSDSYEVPLPPGHRFPMEKYRLLREALLERGVLTPESLTESTPCPRQDLARVHTPRYLDALSQGTLTDAEQRRLGF
PWSPELMRRFSAAVAGTLDAARAALQDGIGGNLSGGTHHGFPDHGEGFCVFNDIAVAIRVLQASRDIRRAVVVDLDVHQG
NGTAAVFTGDDSVFTFSMHGENNFPFRKQPSHLDVGLPDGTGDAAYLDALALHLPEVLDSAGACILFFQAGVDPLTEDAL
GRLSLTHAGLRARDRLVLEAARQRGIPAVLTLGGGYAKPLSATIDAHVGTYEVARALFR

Sequences:

>Translated_299_residues
MRVFHSDSYEVPLPPGHRFPMEKYRLLREALLERGVLTPESLTESTPCPRQDLARVHTPRYLDALSQGTLTDAEQRRLGF
PWSPELMRRFSAAVAGTLDAARAALQDGIGGNLSGGTHHGFPDHGEGFCVFNDIAVAIRVLQASRDIRRAVVVDLDVHQG
NGTAAVFTGDDSVFTFSMHGENNFPFRKQPSHLDVGLPDGTGDAAYLDALALHLPEVLDSAGACILFFQAGVDPLTEDAL
GRLSLTHAGLRARDRLVLEAARQRGIPAVLTLGGGYAKPLSATIDAHVGTYEVARALFR
>Mature_299_residues
MRVFHSDSYEVPLPPGHRFPMEKYRLLREALLERGVLTPESLTESTPCPRQDLARVHTPRYLDALSQGTLTDAEQRRLGF
PWSPELMRRFSAAVAGTLDAARAALQDGIGGNLSGGTHHGFPDHGEGFCVFNDIAVAIRVLQASRDIRRAVVVDLDVHQG
NGTAAVFTGDDSVFTFSMHGENNFPFRKQPSHLDVGLPDGTGDAAYLDALALHLPEVLDSAGACILFFQAGVDPLTEDAL
GRLSLTHAGLRARDRLVLEAARQRGIPAVLTLGGGYAKPLSATIDAHVGTYEVARALFR

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI217272877, Length=272, Percent_Identity=33.0882352941176, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI209862883, Length=272, Percent_Identity=32.3529411764706, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI13128862, Length=284, Percent_Identity=26.4084507042254, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI13128864, Length=280, Percent_Identity=29.2857142857143, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI8923769, Length=247, Percent_Identity=28.3400809716599, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI13128860, Length=305, Percent_Identity=24.5901639344262, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI30795202, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI30795204, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI17158039, Length=135, Percent_Identity=31.8518518518519, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI293336691, Length=169, Percent_Identity=31.3609467455621, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI262073092, Length=160, Percent_Identity=31.875, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193207430, Length=295, Percent_Identity=31.5254237288136, Blast_Score=124, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17561978, Length=304, Percent_Identity=26.3157894736842, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17508561, Length=284, Percent_Identity=26.7605633802817, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17534739, Length=295, Percent_Identity=25.7627118644068, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17537347, Length=247, Percent_Identity=28.7449392712551, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193206283, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17540332, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17540334, Length=145, Percent_Identity=28.9655172413793, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323999, Length=285, Percent_Identity=26.3157894736842, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321244, Length=288, Percent_Identity=27.4305555555556, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6325325, Length=206, Percent_Identity=26.2135922330097, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649807, Length=281, Percent_Identity=33.8078291814947, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24644244, Length=289, Percent_Identity=23.1833910034602, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24657891, Length=305, Percent_Identity=24.9180327868852, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281360899, Length=260, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24642142, Length=266, Percent_Identity=26.6917293233083, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24642146, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24642144, Length=266, Percent_Identity=26.6917293233083, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281360799, Length=221, Percent_Identity=29.8642533936652, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 32356; Mature: 32356

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFHSDSYEVPLPPGHRFPMEKYRLLREALLERGVLTPESLTESTPCPRQDLARVHTPR
CCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHCCCH
YLDALSQGTLTDAEQRRLGFPWSPELMRRFSAAVAGTLDAARAALQDGIGGNLSGGTHHG
HHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FPDHGEGFCVFNDIAVAIRVLQASRDIRRAVVVDLDVHQGNGTAAVFTGDDSVFTFSMHG
CCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCCCEEEEEECC
ENNFPFRKQPSHLDVGLPDGTGDAAYLDALALHLPEVLDSAGACILFFQAGVDPLTEDAL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
GRLSLTHAGLRARDRLVLEAARQRGIPAVLTLGGGYAKPLSATIDAHVGTYEVARALFR
HHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHC
>Mature Secondary Structure
MRVFHSDSYEVPLPPGHRFPMEKYRLLREALLERGVLTPESLTESTPCPRQDLARVHTPR
CCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCCCCHHHHHHHCCCH
YLDALSQGTLTDAEQRRLGFPWSPELMRRFSAAVAGTLDAARAALQDGIGGNLSGGTHHG
HHHHHHCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
FPDHGEGFCVFNDIAVAIRVLQASRDIRRAVVVDLDVHQGNGTAAVFTGDDSVFTFSMHG
CCCCCCCEEEEHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEECCCCEEEEEECC
ENNFPFRKQPSHLDVGLPDGTGDAAYLDALALHLPEVLDSAGACILFFQAGVDPLTEDAL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
GRLSLTHAGLRARDRLVLEAARQRGIPAVLTLGGGYAKPLSATIDAHVGTYEVARALFR
HHHHHHHHCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7678591 [H]