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The map label for this gene is yprA [H]

Identifier: 108758894

GI number: 108758894

Start: 4606607

End: 4608946

Strand: Reverse

Name: yprA [H]

Synonym: MXAN_3833

Alternate gene names: 108758894

Gene position: 4608946-4606607 (Counterclockwise)

Preceding gene: 108760468

Following gene: 108758332

Centisome position: 50.43

GC content: 69.53

Gene sequence:

>2340_bases
GTGCTGGAGGGGTGGCGGTCGGACCGGCAGCTCCGCTCCTGCTTCGTCCTGGATGAGGCCACCCCCGCGCGGGCGGGCGT
CTTCGCGCCCATACCGGAAGAGGTGGCGCCCCAGGTGCGCGACGCGCTCGAGAAGCGGGGCATCCAGCAGCTCTTCTCGC
ACCAGGCGGAGGCGTACCGGCTGGCTCGGGCGGGCCAGAGCCTGGTCATCGCCACGCCCACCGCCTCCGGCAAGAGCCTT
TGTTACAACCTGCCGCTGCTGGACCGCTTCGCGCGGGAGCCCCAGGCGCGGGCGCTGTACCTGTTTCCCACCAAGGCCCT
GTCCAGAGATCAGGAAGAGTCCCTGCGCGCGCTGATGCGCGAGGCGGGCTTGTCCCATGGCGCCATCACCTTCGATGGTG
ACACGCCGGCGGATGCGCGCCGGGCCGCGCGGGAGCGCAGCGGCGTGCTGCTCACCAACCCGGACATGCTGCACACGGGC
ATCCTTCCGCATCACGCGAGCTGGGCGCGCCTGTTCTCCAATCTGCGCTACGTCGTCATCGACGAGCTGCACACGTACCG
GGGCGTCTTCGGCTCTCACCTGGCCAACGTGCTGCGCAGGCTCCAGCGCGTGGCGCGCTTCCACGGCGCGGACCCGGTGT
TCGTCGCGGCGTCGGCCACCATTGGCAATCCGGAGGCCCACGCGAGGCGGATGCTCGGGCGGGACGTGACGCTGGTGTCG
GAGAGCGGGGCGCCTTCCGGCGAGCGCCGCGTCATGGTGTTCAACCCGCCCGTGGTGAACGCGGAGCTGGGCATCCGGGC
CAGCTATCTCAAGACGGCGGTGCGGCTGACGGCCGACTTGGTACGCGCGGGCGTGTCGACGCTGCTCTTCGGACAGTCGC
GCAACAACATCGAGGTGATGCTCAAGTACCTCCGCGACCGCTTCGTCGAGGAGAAGTTGGATCCGTCCCTCATCCAGGGC
TACCGCGGTGGGTATCTACCGGGCACGCGGCGCGCCACGGAGGCGGCGCTGCGGGCGGGTGAAGTCCGCTGCGTGGTGGC
CACCAACGCGCTGGAGCTGGGCATCGACATCGGCTCGCTGGACGCGGTGGTGTGCGCGGGCTACCCGGGTTCGGTGGCGG
CGCTGATGCAGCGATTCGGCCGGGCAGGGCGGCGCGGTGAGGGGAGCCTGGCGCTCCTGGTGACGTCGAGCGCGCCGCTG
GACCAGTACCTCGCCGGCGACCCGCGCTTCCTCGTGGGCTCGCCGGTGGAGCACGCGCGCATCGACCCGGACAACGTGGA
GATCCTGGTCCAGCACCTCAAGTGCGCGTCCTTCGAATTGCCGTTCGAGGAGGGAGAGCCCTTCGGGGACGTACCGCCGG
AGTCCACCACGGAGGCGCTCGGGTTCCTCGCGCAGCACGAGGTGGTGCACCCCACCGTGGGCGAGGCGGGTCGTCGCGTG
TTCCACTGGTCCACGGATGCCTATCCGGCCAACCACGTGTCACTGCGCAGCGTCGGCTGGGACAACGTGGTCATCATCGA
GAAGGGGACGGACCGGACGCTGGCGGAGATGGACTTCCGTTCGGCGCACACGATGCTGCACGAGCAGGCCATCTACCAAC
ACGAGGCCGAGCAGTATCAGGTCGAGCGCTTCGACTACGAGAACCACAAGGCCTTCGTGCGGAAGGTGGCGCCGGACTAC
TTCACCGACGCGATGACCTACGTGCGCGTGCACGTCATCCAGGAGGACCAGGCCGCGCCCATGGGCCCGGACCTTCAGGC
GGGCATGGGCGAGGTGAGCGTCATCGAGAAGGTCGTGGGGTACAAGAAGATCAAGTACCACACGCATGAGAACGTCGGTT
ACGGCGACGTGGCGTTGCCGGAGATGCAGATGCACACCACGGCGCTCTGGCTGACGGTGCCGGAGACGGTGGTGCGCGCC
ATGCGGGCGCCGCGACCGGCGGTCATCGACGCACTGCGCGGCCTGACCACGGCGCTGCGCACGGTGGCGTGCGTGGGGTT
GATGATCGACCCTCGGGATATCGGCAAGACACTGGGGAGCCGGGATGACGCGGAGGGGCCGCCACGCAAGGATGGTGGCG
TGGGCTTCGACCCGACGCTGTTCTTGTACGACAACGTGCCCGGCGGAGTGGGGCTGGCGGCGCGGCTGTACGACCAGCGG
GACGAGCTGCTGAGCCGTGCGCGCCGACTGCTGGAGTCGTGCGCGTGCGAGGATGGCTGTCCGGCGTGTATCGGCCCTGC
CGCGGGGGCGATGCCGGGACAAGCGCCCGTGGACCCGCATCCGCGCAAGCGACTGGCGCTCGAAGTGCTATCGGCGCTGG
GCATCGCGGGAATGCAGTAA

Upstream 100 bases:

>100_bases
ACGTCTGTACAGTGCCCGGCCCATGAAGCCAGAGAAGGAACCGGGCGCTTTCGGAGGGGCCCGTCGCACGCCGTGGAACG
CGCCTCGCGGGTTGGACTCC

Downstream 100 bases:

>100_bases
CCGGGAGGCGCGGCCGTGGACCTCAAGCGCAAGCTGGCGCGCCTGACGAGCGTGGGCCCCGGGGGCAAGTCACCCCCGAA
GCCCCCCGTGGCGGAGCCAC

Product: DEAD-box ATP dependent DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MLEGWRSDRQLRSCFVLDEATPARAGVFAPIPEEVAPQVRDALEKRGIQQLFSHQAEAYRLARAGQSLVIATPTASGKSL
CYNLPLLDRFAREPQARALYLFPTKALSRDQEESLRALMREAGLSHGAITFDGDTPADARRAARERSGVLLTNPDMLHTG
ILPHHASWARLFSNLRYVVIDELHTYRGVFGSHLANVLRRLQRVARFHGADPVFVAASATIGNPEAHARRMLGRDVTLVS
ESGAPSGERRVMVFNPPVVNAELGIRASYLKTAVRLTADLVRAGVSTLLFGQSRNNIEVMLKYLRDRFVEEKLDPSLIQG
YRGGYLPGTRRATEAALRAGEVRCVVATNALELGIDIGSLDAVVCAGYPGSVAALMQRFGRAGRRGEGSLALLVTSSAPL
DQYLAGDPRFLVGSPVEHARIDPDNVEILVQHLKCASFELPFEEGEPFGDVPPESTTEALGFLAQHEVVHPTVGEAGRRV
FHWSTDAYPANHVSLRSVGWDNVVIIEKGTDRTLAEMDFRSAHTMLHEQAIYQHEAEQYQVERFDYENHKAFVRKVAPDY
FTDAMTYVRVHVIQEDQAAPMGPDLQAGMGEVSVIEKVVGYKKIKYHTHENVGYGDVALPEMQMHTTALWLTVPETVVRA
MRAPRPAVIDALRGLTTALRTVACVGLMIDPRDIGKTLGSRDDAEGPPRKDGGVGFDPTLFLYDNVPGGVGLAARLYDQR
DELLSRARRLLESCACEDGCPACIGPAAGAMPGQAPVDPHPRKRLALEVLSALGIAGMQ

Sequences:

>Translated_779_residues
MLEGWRSDRQLRSCFVLDEATPARAGVFAPIPEEVAPQVRDALEKRGIQQLFSHQAEAYRLARAGQSLVIATPTASGKSL
CYNLPLLDRFAREPQARALYLFPTKALSRDQEESLRALMREAGLSHGAITFDGDTPADARRAARERSGVLLTNPDMLHTG
ILPHHASWARLFSNLRYVVIDELHTYRGVFGSHLANVLRRLQRVARFHGADPVFVAASATIGNPEAHARRMLGRDVTLVS
ESGAPSGERRVMVFNPPVVNAELGIRASYLKTAVRLTADLVRAGVSTLLFGQSRNNIEVMLKYLRDRFVEEKLDPSLIQG
YRGGYLPGTRRATEAALRAGEVRCVVATNALELGIDIGSLDAVVCAGYPGSVAALMQRFGRAGRRGEGSLALLVTSSAPL
DQYLAGDPRFLVGSPVEHARIDPDNVEILVQHLKCASFELPFEEGEPFGDVPPESTTEALGFLAQHEVVHPTVGEAGRRV
FHWSTDAYPANHVSLRSVGWDNVVIIEKGTDRTLAEMDFRSAHTMLHEQAIYQHEAEQYQVERFDYENHKAFVRKVAPDY
FTDAMTYVRVHVIQEDQAAPMGPDLQAGMGEVSVIEKVVGYKKIKYHTHENVGYGDVALPEMQMHTTALWLTVPETVVRA
MRAPRPAVIDALRGLTTALRTVACVGLMIDPRDIGKTLGSRDDAEGPPRKDGGVGFDPTLFLYDNVPGGVGLAARLYDQR
DELLSRARRLLESCACEDGCPACIGPAAGAMPGQAPVDPHPRKRLALEVLSALGIAGMQ
>Mature_779_residues
MLEGWRSDRQLRSCFVLDEATPARAGVFAPIPEEVAPQVRDALEKRGIQQLFSHQAEAYRLARAGQSLVIATPTASGKSL
CYNLPLLDRFAREPQARALYLFPTKALSRDQEESLRALMREAGLSHGAITFDGDTPADARRAARERSGVLLTNPDMLHTG
ILPHHASWARLFSNLRYVVIDELHTYRGVFGSHLANVLRRLQRVARFHGADPVFVAASATIGNPEAHARRMLGRDVTLVS
ESGAPSGERRVMVFNPPVVNAELGIRASYLKTAVRLTADLVRAGVSTLLFGQSRNNIEVMLKYLRDRFVEEKLDPSLIQG
YRGGYLPGTRRATEAALRAGEVRCVVATNALELGIDIGSLDAVVCAGYPGSVAALMQRFGRAGRRGEGSLALLVTSSAPL
DQYLAGDPRFLVGSPVEHARIDPDNVEILVQHLKCASFELPFEEGEPFGDVPPESTTEALGFLAQHEVVHPTVGEAGRRV
FHWSTDAYPANHVSLRSVGWDNVVIIEKGTDRTLAEMDFRSAHTMLHEQAIYQHEAEQYQVERFDYENHKAFVRKVAPDY
FTDAMTYVRVHVIQEDQAAPMGPDLQAGMGEVSVIEKVVGYKKIKYHTHENVGYGDVALPEMQMHTTALWLTVPETVVRA
MRAPRPAVIDALRGLTTALRTVACVGLMIDPRDIGKTLGSRDDAEGPPRKDGGVGFDPTLFLYDNVPGGVGLAARLYDQR
DELLSRARRLLESCACEDGCPACIGPAAGAMPGQAPVDPHPRKRLALEVLSALGIAGMQ

Specific function: Unknown

COG id: COG1205

COG function: function code R; Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI284005309, Length=375, Percent_Identity=25.8666666666667, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI1787942, Length=424, Percent_Identity=29.9528301886792, Blast_Score=107, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI71987993, Length=387, Percent_Identity=24.2894056847545, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71987997, Length=427, Percent_Identity=24.3559718969555, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320497, Length=777, Percent_Identity=30.3732303732304, Blast_Score=377, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR018973
- InterPro:   IPR011545
- InterPro:   IPR001650
- InterPro:   IPR014021 [H]

Pfam domain/function: PF00270 DEAD; PF09369 DUF1998; PF00271 Helicase_C [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 85283; Mature: 85283

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGWRSDRQLRSCFVLDEATPARAGVFAPIPEEVAPQVRDALEKRGIQQLFSHQAEAYR
CCCCCCCHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARAGQSLVIATPTASGKSLCYNLPLLDRFAREPQARALYLFPTKALSRDQEESLRALMR
HHHCCCEEEEECCCCCCCCEEEECCHHHHHHCCCCCCEEEEECCHHHCCCHHHHHHHHHH
EAGLSHGAITFDGDTPADARRAARERSGVLLTNPDMLHTGILPHHASWARLFSNLRYVVI
HCCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCHHHCCCCCCCHHHHHHHHCCCEEEE
DELHTYRGVFGSHLANVLRRLQRVARFHGADPVFVAASATIGNPEAHARRMLGRDVTLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEE
ESGAPSGERRVMVFNPPVVNAELGIRASYLKTAVRLTADLVRAGVSTLLFGQSRNNIEVM
CCCCCCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
LKYLRDRFVEEKLDPSLIQGYRGGYLPGTRRATEAALRAGEVRCVVATNALELGIDIGSL
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEECCEEECCCCCCC
DAVVCAGYPGSVAALMQRFGRAGRRGEGSLALLVTSSAPLDQYLAGDPRFLVGSPVEHAR
CEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCCEEECCCHHHCC
IDPDNVEILVQHLKCASFELPFEEGEPFGDVPPESTTEALGFLAQHEVVHPTVGEAGRRV
CCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEE
FHWSTDAYPANHVSLRSVGWDNVVIIEKGTDRTLAEMDFRSAHTMLHEQAIYQHEAEQYQ
EEECCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VERFDYENHKAFVRKVAPDYFTDAMTYVRVHVIQEDQAAPMGPDLQAGMGEVSVIEKVVG
HHHCCCCHHHHHHHHHCCHHHHHHHHHHEEEEEECCCCCCCCCCHHCCCCHHHHHHHHHC
YKKIKYHTHENVGYGDVALPEMQMHTTALWLTVPETVVRAMRAPRPAVIDALRGLTTALR
HHHEEEECCCCCCCCCCCCCCHHHEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHH
TVACVGLMIDPRDIGKTLGSRDDAEGPPRKDGGVGFDPTLFLYDNVPGGVGLAARLYDQR
HHHHHHEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
DELLSRARRLLESCACEDGCPACIGPAAGAMPGQAPVDPHPRKRLALEVLSALGIAGMQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLEGWRSDRQLRSCFVLDEATPARAGVFAPIPEEVAPQVRDALEKRGIQQLFSHQAEAYR
CCCCCCCHHHHHHEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LARAGQSLVIATPTASGKSLCYNLPLLDRFAREPQARALYLFPTKALSRDQEESLRALMR
HHHCCCEEEEECCCCCCCCEEEECCHHHHHHCCCCCCEEEEECCHHHCCCHHHHHHHHHH
EAGLSHGAITFDGDTPADARRAARERSGVLLTNPDMLHTGILPHHASWARLFSNLRYVVI
HCCCCCCEEEECCCCCHHHHHHHHHHCCEEEECCCHHHCCCCCCCHHHHHHHHCCCEEEE
DELHTYRGVFGSHLANVLRRLQRVARFHGADPVFVAASATIGNPEAHARRMLGRDVTLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHCCCEEEEE
ESGAPSGERRVMVFNPPVVNAELGIRASYLKTAVRLTADLVRAGVSTLLFGQSRNNIEVM
CCCCCCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
LKYLRDRFVEEKLDPSLIQGYRGGYLPGTRRATEAALRAGEVRCVVATNALELGIDIGSL
HHHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEEEECCEEECCCCCCC
DAVVCAGYPGSVAALMQRFGRAGRRGEGSLALLVTSSAPLDQYLAGDPRFLVGSPVEHAR
CEEEECCCCCHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHCCCCCEEECCCHHHCC
IDPDNVEILVQHLKCASFELPFEEGEPFGDVPPESTTEALGFLAQHEVVHPTVGEAGRRV
CCCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEE
FHWSTDAYPANHVSLRSVGWDNVVIIEKGTDRTLAEMDFRSAHTMLHEQAIYQHEAEQYQ
EEECCCCCCCCCEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VERFDYENHKAFVRKVAPDYFTDAMTYVRVHVIQEDQAAPMGPDLQAGMGEVSVIEKVVG
HHHCCCCHHHHHHHHHCCHHHHHHHHHHEEEEEECCCCCCCCCCHHCCCCHHHHHHHHHC
YKKIKYHTHENVGYGDVALPEMQMHTTALWLTVPETVVRAMRAPRPAVIDALRGLTTALR
HHHEEEECCCCCCCCCCCCCCHHHEEEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHH
TVACVGLMIDPRDIGKTLGSRDDAEGPPRKDGGVGFDPTLFLYDNVPGGVGLAARLYDQR
HHHHHHEEECHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHH
DELLSRARRLLESCACEDGCPACIGPAAGAMPGQAPVDPHPRKRLALEVLSALGIAGMQ
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on acid anhydrides [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]