Click here to switch to the map view.

The map label for this gene is pgm [H]

Identifier: 108758440

GI number: 108758440

Start: 6121233

End: 6122870

Strand: Direct

Name: pgm [H]

Synonym: MXAN_4888

Alternate gene names: 108758440

Gene position: 6121233-6122870 (Clockwise)

Preceding gene: 108762729

Following gene: 108758034

Centisome position: 66.97

GC content: 69.54

Gene sequence:

>1638_bases
ATGGCCCACCCGCTCGCTGGCAAGCCCCCTCCGGAAGACTTCCTCATCGACCCCGAGAAACTGCGCGCCGCGTACTTCTC
CGGCCGGCCCGACGTGGACGTGCCGGAGCAACGCGTGGCCTTCGGCACCTCCGGGCACCGCGGTTCCTCCGCGCGCAACA
GCTTCAACGAAGGCCACATCCTCGCGGTGACGCAGGCCATCTGCGAGTACCGCCAGCAGCAGGGCATCGACGGGCCGCTC
TTCCTGGGCATGGACACCCACGCCCTCTCCTCCCCCGCGCAGCAGACGGCGCTGGAGGTGCTGGCGGCGAACGGCGTGCA
GGTGCGCTTCACCGACGGCGCCACGCCCACGCCCGTCATCTCCCACGCCATCCTCACGTACAACCGCGGCCGCACGGCGG
GGTTCGCGGACGGCATCGTCATCACCCCGTCCCACAACCCGCCGGAAGACGGTGGCATCAAGTACAACCCGCCCAACGGC
GGCCCCGCGGACACGAACGTCACCTCCGTCATCGAGAAGCGCGCCAACGCGCTGCTGGGTGCGGGCAACGAGGGCGTCCA
GCGCATCCCCCACGAGCGCGCGCGCACCGCGCCCACGGTGAAGCCGTACGACTTCATCACCCCGTACGTGGAGGACCTGG
GCACCGTCATCGACATGGAGGCCCTGCGCGGTGCGAAGCTGCGCATCGGCGCGGACCCGCTCGGCGGCTCCAACGTCGCG
TACTGGGAGCCCATCGCCACGCGCTACGGGCTGAACCTGCACGTGGTGAACCCCACGGTGGACCCGACGTTCCGGTTCAT
GCCGCTGGACCACGACGGGAAGATTCGCATGGACTGCTCGTCCCCGCATGCCATGGCGAACCTGGTGCGCCTGAAGGACG
CGTATGACATCGCGTTTGGCAACGACGCGGACTCGGACCGGCACGGCATCGTCACCCGCAGCCTGGGGCTGATGAACCCG
AACCACTACCTGGCGGTCGCCATCGACTACCTCTATCGCAACCGGCCCGGCTGGAAGCCCGGCACCGCGGTGGGCAAGAC
ACTGGTGAGCAGCAGCCTCATCGACCGCGTGGCGAAGGACCTGGGCCGCCGAGTCGTCGAGGTGCCGGTGGGCTTCAAGT
GGTTCGTGGACGGGCTGCTGGACGGCTCGCTCGGCTTCGGCGGCGAGGAAAGCGCCGGCGCGTCGTTCCTCCGCCGAGAC
GGCACGGTGTGGACCACCGACAAGGACGGCATCATCCTGGACCTGCTGTCGGTGGAGATCCTCGCGCGCACCGGAAAGGA
CCCCGGTGAGCACTACCAGTCCCTGGCGGCGAAGTTCGGCGCGCCGCACTACACGCGCATCGACCAGCCGGCCACCGCCG
CGCAGAAGGCCGCGCTGAAGAAGCTGTCCCCGGAGGCGGTGAAGGCCACCACGCTGGCCGGTGAGCCCATCCTCCAGCGC
CTCACCCGCGCGCCCGGCAACAACGCGGACATCGGCGGGCTCAAGGTGGTGGCGGAGAACGGCTGGTTCGCCGCGCGTCC
CTCCGGCACCGAGGACGTCTACAAAATCTACGCGGAGAGCTTCCGCGACGAAGCCCACCTCCAAGACATCCTCCAGGAGG
CGCGCGCCATCGTCGGCGAGGCGTTCGCGTCGACTTGA

Upstream 100 bases:

>100_bases
CCCTGAGCGTCGGCGCCGCGTCACCGGAGGATGTAACGCGGTGCACGCTCGCCAGAATCGTTGAGCCTTCCGCCGTGGGG
CATGGCTATGTTCCGCGGCC

Downstream 100 bases:

>100_bases
GCGGCGTGGCGGAGGTGCTGCTGGGCGTGGACCTGGCCATCCTCCACGCGAGCGGGCTGGCAGCCGGGGCCTCGTCGCCC
TGTTCATCGCCGTCTTTCCA

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MAHPLAGKPPPEDFLIDPEKLRAAYFSGRPDVDVPEQRVAFGTSGHRGSSARNSFNEGHILAVTQAICEYRQQQGIDGPL
FLGMDTHALSSPAQQTALEVLAANGVQVRFTDGATPTPVISHAILTYNRGRTAGFADGIVITPSHNPPEDGGIKYNPPNG
GPADTNVTSVIEKRANALLGAGNEGVQRIPHERARTAPTVKPYDFITPYVEDLGTVIDMEALRGAKLRIGADPLGGSNVA
YWEPIATRYGLNLHVVNPTVDPTFRFMPLDHDGKIRMDCSSPHAMANLVRLKDAYDIAFGNDADSDRHGIVTRSLGLMNP
NHYLAVAIDYLYRNRPGWKPGTAVGKTLVSSSLIDRVAKDLGRRVVEVPVGFKWFVDGLLDGSLGFGGEESAGASFLRRD
GTVWTTDKDGIILDLLSVEILARTGKDPGEHYQSLAAKFGAPHYTRIDQPATAAQKAALKKLSPEAVKATTLAGEPILQR
LTRAPGNNADIGGLKVVAENGWFAARPSGTEDVYKIYAESFRDEAHLQDILQEARAIVGEAFAST

Sequences:

>Translated_545_residues
MAHPLAGKPPPEDFLIDPEKLRAAYFSGRPDVDVPEQRVAFGTSGHRGSSARNSFNEGHILAVTQAICEYRQQQGIDGPL
FLGMDTHALSSPAQQTALEVLAANGVQVRFTDGATPTPVISHAILTYNRGRTAGFADGIVITPSHNPPEDGGIKYNPPNG
GPADTNVTSVIEKRANALLGAGNEGVQRIPHERARTAPTVKPYDFITPYVEDLGTVIDMEALRGAKLRIGADPLGGSNVA
YWEPIATRYGLNLHVVNPTVDPTFRFMPLDHDGKIRMDCSSPHAMANLVRLKDAYDIAFGNDADSDRHGIVTRSLGLMNP
NHYLAVAIDYLYRNRPGWKPGTAVGKTLVSSSLIDRVAKDLGRRVVEVPVGFKWFVDGLLDGSLGFGGEESAGASFLRRD
GTVWTTDKDGIILDLLSVEILARTGKDPGEHYQSLAAKFGAPHYTRIDQPATAAQKAALKKLSPEAVKATTLAGEPILQR
LTRAPGNNADIGGLKVVAENGWFAARPSGTEDVYKIYAESFRDEAHLQDILQEARAIVGEAFAST
>Mature_544_residues
AHPLAGKPPPEDFLIDPEKLRAAYFSGRPDVDVPEQRVAFGTSGHRGSSARNSFNEGHILAVTQAICEYRQQQGIDGPLF
LGMDTHALSSPAQQTALEVLAANGVQVRFTDGATPTPVISHAILTYNRGRTAGFADGIVITPSHNPPEDGGIKYNPPNGG
PADTNVTSVIEKRANALLGAGNEGVQRIPHERARTAPTVKPYDFITPYVEDLGTVIDMEALRGAKLRIGADPLGGSNVAY
WEPIATRYGLNLHVVNPTVDPTFRFMPLDHDGKIRMDCSSPHAMANLVRLKDAYDIAFGNDADSDRHGIVTRSLGLMNPN
HYLAVAIDYLYRNRPGWKPGTAVGKTLVSSSLIDRVAKDLGRRVVEVPVGFKWFVDGLLDGSLGFGGEESAGASFLRRDG
TVWTTDKDGIILDLLSVEILARTGKDPGEHYQSLAAKFGAPHYTRIDQPATAAQKAALKKLSPEAVKATTLAGEPILQRL
TRAPGNNADIGGLKVVAENGWFAARPSGTEDVYKIYAESFRDEAHLQDILQEARAIVGEAFAST

Specific function: This enzyme participates in both the breakdown and synthesis of glucose [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI133922562, Length=528, Percent_Identity=23.4848484848485, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI290463102, Length=444, Percent_Identity=26.5765765765766, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI21361621, Length=444, Percent_Identity=26.5765765765766, Blast_Score=85, Evalue=2e-16,
Organism=Escherichia coli, GI1786904, Length=542, Percent_Identity=62.9151291512915, Blast_Score=663, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17535441, Length=458, Percent_Identity=27.0742358078603, Blast_Score=95, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322722, Length=537, Percent_Identity=28.8640595903166, Blast_Score=101, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6323752, Length=536, Percent_Identity=27.0522388059701, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17864244, Length=417, Percent_Identity=27.5779376498801, Blast_Score=103, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005852 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 58653; Mature: 58521

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHPLAGKPPPEDFLIDPEKLRAAYFSGRPDVDVPEQRVAFGTSGHRGSSARNSFNEGHI
CCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHEECCCCCCCCCHHCCCCCCCC
LAVTQAICEYRQQQGIDGPLFLGMDTHALSSPAQQTALEVLAANGVQVRFTDGATPTPVI
HHHHHHHHHHHHHCCCCCCEEECCCHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCHHH
SHAILTYNRGRTAGFADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTSVIEKRANALLG
HHHHEEECCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHC
AGNEGVQRIPHERARTAPTVKPYDFITPYVEDLGTVIDMEALRGAKLRIGADPLGGSNVA
CCCHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCE
YWEPIATRYGLNLHVVNPTVDPTFRFMPLDHDGKIRMDCSSPHAMANLVRLKDAYDIAFG
EECHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHEEEEEC
NDADSDRHGIVTRSLGLMNPNHYLAVAIDYLYRNRPGWKPGTAVGKTLVSSSLIDRVAKD
CCCCCCCCCEEEHHHCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGRRVVEVPVGFKWFVDGLLDGSLGFGGEESAGASFLRRDGTVWTTDKDGIILDLLSVEI
HCCEEEECCCCHHHHHHHHHCCCCCCCCCCHHCHHHHHCCCCEEECCCCCEEEHHHHHHH
LARTGKDPGEHYQSLAAKFGAPHYTRIDQPATAAQKAALKKLSPEAVKATTLAGEPILQR
HHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
LTRAPGNNADIGGLKVVAENGWFAARPSGTEDVYKIYAESFRDEAHLQDILQEARAIVGE
HHCCCCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AFAST
HHHCC
>Mature Secondary Structure 
AHPLAGKPPPEDFLIDPEKLRAAYFSGRPDVDVPEQRVAFGTSGHRGSSARNSFNEGHI
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHEECCCCCCCCCHHCCCCCCCC
LAVTQAICEYRQQQGIDGPLFLGMDTHALSSPAQQTALEVLAANGVQVRFTDGATPTPVI
HHHHHHHHHHHHHCCCCCCEEECCCHHHHCCHHHHHHHHHHHCCCEEEEECCCCCCCHHH
SHAILTYNRGRTAGFADGIVITPSHNPPEDGGIKYNPPNGGPADTNVTSVIEKRANALLG
HHHHEEECCCCCCCCCCCEEECCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHC
AGNEGVQRIPHERARTAPTVKPYDFITPYVEDLGTVIDMEALRGAKLRIGADPLGGSNVA
CCCHHHHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCE
YWEPIATRYGLNLHVVNPTVDPTFRFMPLDHDGKIRMDCSSPHAMANLVRLKDAYDIAFG
EECHHHHHCCCEEEEECCCCCCCEEEEECCCCCCEEEECCCCHHHHHHHHHHHHEEEEEC
NDADSDRHGIVTRSLGLMNPNHYLAVAIDYLYRNRPGWKPGTAVGKTLVSSSLIDRVAKD
CCCCCCCCCEEEHHHCCCCCCCEEEEEEEHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LGRRVVEVPVGFKWFVDGLLDGSLGFGGEESAGASFLRRDGTVWTTDKDGIILDLLSVEI
HCCEEEECCCCHHHHHHHHHCCCCCCCCCCHHCHHHHHCCCCEEECCCCCEEEHHHHHHH
LARTGKDPGEHYQSLAAKFGAPHYTRIDQPATAAQKAALKKLSPEAVKATTLAGEPILQR
HHHCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
LTRAPGNNADIGGLKVVAENGWFAARPSGTEDVYKIYAESFRDEAHLQDILQEARAIVGE
HHCCCCCCCCCCCEEEEEECCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AFAST
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8025683 [H]