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The map label for this gene is lolC [H]

Identifier: 108757531

GI number: 108757531

Start: 6748056

End: 6750422

Strand: Reverse

Name: lolC [H]

Synonym: MXAN_5419

Alternate gene names: 108757531

Gene position: 6750422-6748056 (Counterclockwise)

Preceding gene: 108762447

Following gene: 108763443

Centisome position: 73.86

GC content: 68.44

Gene sequence:

>2367_bases
GTGCGCTCCGCGGAACGGCAGACCGTCTATCGCTGGACCTTCATCTGGATGGGGGCCCTGGTCGCCCTCGCGGGCTTCGC
CTTGCTCGGGGTGGCGCTCACGTCCGCCCATGCTTGGGAGGAGGCCAGCCCCGCGCTGGGGCTCTCCCTGCTGGGCTGGG
GCGGCCTGGTCCAGGCCCTGAACGCGGCGCTGCTGGTGTCCCGGCAGGCCGTCGCGCCGCTGCCCAACACCGGCGTGCTG
CTGGCGGGGACGGCCGTCTGGCTCGTGGGGTGGGGGCTCATCGCTGCGGGCATCCGCCGCGCGCCGGCGTCCACGGAAGG
CCCCAGCCCGGCCGCGGGCGCCACGCTGTACCCGCGGCTGGCGCGCTACCGGGACTTCTACTGGAGCACCCTGGGTGCCT
ACGGCGGCGGCATCCTGCTGTCGGAGGTCGTCCTCATCCTCCTGCAGACGGTGCTGTCCAGCGGGGGGGCGACCAACGAA
CTGGCGGGCACGGCGAAGGGGGGCGGCGGCCTGTCGCTGGCGCCCACCGGCGCCTTCGCCATCGCGTTGATGGCCGGCGG
GATGGTGGCGTTCATCTCCGGCTTCATCGGCGCCTCGCGGGCGCAGCGGCTGTCGCTGCCCGAGGCCACCATCGGCGTGC
TGTACCTGGGCCTGCCCATCCCCATCGTCCTCACGCTGATGGAGCGGCTGCCTGGGCTCCAGCTCGCGCTGGGCTACCGG
CTGCGCGAGGTGACGTACGTCGCGGGGCTTATCGGCCGCCCGGAGCTGGGGTACTGGCTCGTCTTCATGTTCCTGGTGCT
GGCGCTGGTGCTGGGCGTCAACACCGGCTTCATCGCCGCCGGCAGTGGCCGCGTCGACCTGAAGATGGGCTTCGAGCTCT
TCGTCGCGCGCCGGCACGTGGCGGTGTTCCGCCCCTCGCTGCTGCTGGGGACGCTGGCGGTACTGATGCTCGGCATCATT
CCTCCGCTGCTCATCTACTTCATCATCCGCTCGGCGGAAGCCGCGGTGGAGCGCACCCGCATCCGCAAGCTGGGGCTGAA
GGACCCGCTGGCGGCCGCCTCCGACCTCAACCGCCTCAAGCAGCACGAGCAGTCCCCCACCATGATGATGACGGCCCTGT
CGGTGGGCGGCGTGGGCGTGGGGGTGATGGCGCTCATCATCGTCCTGTCGGTGATGAGCGGCTTCGAGGCGGACCTGCAG
CAGAAAATCCTGGGCACCAACGCGCACGCCGTGGTGTCCAAGTACGCGGGCGACCTGCCCGAGTACGCCAAGGTCATGGA
GTCCGTCCGCAAGGTGCCCGGTGTCGTGGGACAGACGCCCTTCATCATCAACCAGGTGATGATTGCGTCCGAGGGCAACG
TGGACGGCGTCATCATCAAGGGCATCGACCCGGGCACGGTGGGCGAGGTGACGGACCTGCCCAAGAACATCCTCGGTGGC
GGCTCGCTCGACACCCTCTATACGCCGGAGAAGATCGTCCACCGCGGCCTGCCGGACGAGGAGCCCGCCGAGGAGGGTGG
GGTGGAGGAGGACGAAATCATCCGCCGATCCGGTACGCCCAAGAAGCCGCAGGTGCTGCCCGGCATCGTCATCGGCCGGG
AGCTGGCGGCGTCGCTGCGCGTGGTGGTGGGAGACCGGGTGAACGTCGTGTCCCCGCTGGGCACCGAGCTGGGGCCCATT
GGCCCGATTCCGAAGAGCCGCGCCTTCCGCGTGGCGGCCATCTTCTACTCGGGCATGTACGAGTATGACTCCAAGTTCGT
CTACATCCTGCTCAAGGAGGCCCAGGACTTCTTCGACATGAAGGGCGCCACGGGCATCGAGTTGAAGGTGGCGGACATCG
ACGACGCGCGGCGCATCGCCTCCCAGGTGGTGAAGGCGCTGGGTGGCTACCCCTACCGGGCGAGGGACTGGGGTGAGATG
AACAAGAACTTCTTCTCCGCGCTGCGCCTACAGAAGCTGGTGATGGGCATCATCCTCTCCATCATCATCATCGTGGCCGC
GGGTCTCATCGTCGCCACCGTCATCATGCTGGTGCTGGAGAAGCGGAAGGAGATCTCCGTCCTCAAGGCGCTGGGCGTCC
CGGATGGTGGCATCGTGAAGATATTCCTCGCAGAGGGCCTGCAAATTGGCGTCGCGGGCGGCCTCCTCGGTCTGCTGTCC
GGCCTCTCCTCGTGCTTCTTCATCGAGAAGGTTGGCATCAAGCTGGACCCGGGCGTGTATTTCATGTCGGCGCTGCCGGT
GCGCATCGAGCCGGTGCAGACCGTGCTGGCCGTCGTCATCGCGGTGCTCGTCACCTACCTCGCCTCCATCTACCCGGCCC
TCAAGGCCAGCAGCGTGGAGCCAGTCGAAGGCCTCAAGGCGGAGTAG

Upstream 100 bases:

>100_bases
CTGCTGGAGGACCATCCATGCTGTTCACGGATTCGTAGAGCATCCGGGACGTCATCTTGTTCCCCCTCTCCAGCCACTGG
CGAAGTAGCTCGGAGGGCGC

Downstream 100 bases:

>100_bases
TCTGGACCGAAAGGGCCGCCGTCGTGGCAGCGAGCAGGCTTCGAAGCGGCTGGCGGCTCGGCTCAATCGAAGTCAGTCGG
AAGCGCGGCGTCGCGCGCGT

Product: LolC/E family lipoprotein releasing system, transmembrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MRSAERQTVYRWTFIWMGALVALAGFALLGVALTSAHAWEEASPALGLSLLGWGGLVQALNAALLVSRQAVAPLPNTGVL
LAGTAVWLVGWGLIAAGIRRAPASTEGPSPAAGATLYPRLARYRDFYWSTLGAYGGGILLSEVVLILLQTVLSSGGATNE
LAGTAKGGGGLSLAPTGAFAIALMAGGMVAFISGFIGASRAQRLSLPEATIGVLYLGLPIPIVLTLMERLPGLQLALGYR
LREVTYVAGLIGRPELGYWLVFMFLVLALVLGVNTGFIAAGSGRVDLKMGFELFVARRHVAVFRPSLLLGTLAVLMLGII
PPLLIYFIIRSAEAAVERTRIRKLGLKDPLAAASDLNRLKQHEQSPTMMMTALSVGGVGVGVMALIIVLSVMSGFEADLQ
QKILGTNAHAVVSKYAGDLPEYAKVMESVRKVPGVVGQTPFIINQVMIASEGNVDGVIIKGIDPGTVGEVTDLPKNILGG
GSLDTLYTPEKIVHRGLPDEEPAEEGGVEEDEIIRRSGTPKKPQVLPGIVIGRELAASLRVVVGDRVNVVSPLGTELGPI
GPIPKSRAFRVAAIFYSGMYEYDSKFVYILLKEAQDFFDMKGATGIELKVADIDDARRIASQVVKALGGYPYRARDWGEM
NKNFFSALRLQKLVMGIILSIIIIVAAGLIVATVIMLVLEKRKEISVLKALGVPDGGIVKIFLAEGLQIGVAGGLLGLLS
GLSSCFFIEKVGIKLDPGVYFMSALPVRIEPVQTVLAVVIAVLVTYLASIYPALKASSVEPVEGLKAE

Sequences:

>Translated_788_residues
MRSAERQTVYRWTFIWMGALVALAGFALLGVALTSAHAWEEASPALGLSLLGWGGLVQALNAALLVSRQAVAPLPNTGVL
LAGTAVWLVGWGLIAAGIRRAPASTEGPSPAAGATLYPRLARYRDFYWSTLGAYGGGILLSEVVLILLQTVLSSGGATNE
LAGTAKGGGGLSLAPTGAFAIALMAGGMVAFISGFIGASRAQRLSLPEATIGVLYLGLPIPIVLTLMERLPGLQLALGYR
LREVTYVAGLIGRPELGYWLVFMFLVLALVLGVNTGFIAAGSGRVDLKMGFELFVARRHVAVFRPSLLLGTLAVLMLGII
PPLLIYFIIRSAEAAVERTRIRKLGLKDPLAAASDLNRLKQHEQSPTMMMTALSVGGVGVGVMALIIVLSVMSGFEADLQ
QKILGTNAHAVVSKYAGDLPEYAKVMESVRKVPGVVGQTPFIINQVMIASEGNVDGVIIKGIDPGTVGEVTDLPKNILGG
GSLDTLYTPEKIVHRGLPDEEPAEEGGVEEDEIIRRSGTPKKPQVLPGIVIGRELAASLRVVVGDRVNVVSPLGTELGPI
GPIPKSRAFRVAAIFYSGMYEYDSKFVYILLKEAQDFFDMKGATGIELKVADIDDARRIASQVVKALGGYPYRARDWGEM
NKNFFSALRLQKLVMGIILSIIIIVAAGLIVATVIMLVLEKRKEISVLKALGVPDGGIVKIFLAEGLQIGVAGGLLGLLS
GLSSCFFIEKVGIKLDPGVYFMSALPVRIEPVQTVLAVVIAVLVTYLASIYPALKASSVEPVEGLKAE
>Mature_788_residues
MRSAERQTVYRWTFIWMGALVALAGFALLGVALTSAHAWEEASPALGLSLLGWGGLVQALNAALLVSRQAVAPLPNTGVL
LAGTAVWLVGWGLIAAGIRRAPASTEGPSPAAGATLYPRLARYRDFYWSTLGAYGGGILLSEVVLILLQTVLSSGGATNE
LAGTAKGGGGLSLAPTGAFAIALMAGGMVAFISGFIGASRAQRLSLPEATIGVLYLGLPIPIVLTLMERLPGLQLALGYR
LREVTYVAGLIGRPELGYWLVFMFLVLALVLGVNTGFIAAGSGRVDLKMGFELFVARRHVAVFRPSLLLGTLAVLMLGII
PPLLIYFIIRSAEAAVERTRIRKLGLKDPLAAASDLNRLKQHEQSPTMMMTALSVGGVGVGVMALIIVLSVMSGFEADLQ
QKILGTNAHAVVSKYAGDLPEYAKVMESVRKVPGVVGQTPFIINQVMIASEGNVDGVIIKGIDPGTVGEVTDLPKNILGG
GSLDTLYTPEKIVHRGLPDEEPAEEGGVEEDEIIRRSGTPKKPQVLPGIVIGRELAASLRVVVGDRVNVVSPLGTELGPI
GPIPKSRAFRVAAIFYSGMYEYDSKFVYILLKEAQDFFDMKGATGIELKVADIDDARRIASQVVKALGGYPYRARDWGEM
NKNFFSALRLQKLVMGIILSIIIIVAAGLIVATVIMLVLEKRKEISVLKALGVPDGGIVKIFLAEGLQIGVAGGLLGLLS
GLSSCFFIEKVGIKLDPGVYFMSALPVRIEPVQTVLAVVIAVLVTYLASIYPALKASSVEPVEGLKAE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787360, Length=424, Percent_Identity=27.8301886792453, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787362, Length=431, Percent_Identity=26.9141531322506, Blast_Score=130, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 83349; Mature: 83349

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSAERQTVYRWTFIWMGALVALAGFALLGVALTSAHAWEEASPALGLSLLGWGGLVQAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
NAALLVSRQAVAPLPNTGVLLAGTAVWLVGWGLIAAGIRRAPASTEGPSPAAGATLYPRL
HHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
ARYRDFYWSTLGAYGGGILLSEVVLILLQTVLSSGGATNELAGTAKGGGGLSLAPTGAFA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCHHHHH
IALMAGGMVAFISGFIGASRAQRLSLPEATIGVLYLGLPIPIVLTLMERLPGLQLALGYR
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCEEHHHHH
LREVTYVAGLIGRPELGYWLVFMFLVLALVLGVNTGFIAAGSGRVDLKMGFELFVARRHV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHH
AVFRPSLLLGTLAVLMLGIIPPLLIYFIIRSAEAAVERTRIRKLGLKDPLAAASDLNRLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QHEQSPTMMMTALSVGGVGVGVMALIIVLSVMSGFEADLQQKILGTNAHAVVSKYAGDLP
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHCCCH
EYAKVMESVRKVPGVVGQTPFIINQVMIASEGNVDGVIIKGIDPGTVGEVTDLPKNILGG
HHHHHHHHHHHCCCCCCCCCHHHHHEEEECCCCCCEEEEECCCCCCCCCHHHCCHHHCCC
GSLDTLYTPEKIVHRGLPDEEPAEEGGVEEDEIIRRSGTPKKPQVLPGIVIGRELAASLR
CCCCCCCCCHHHHHCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VVVGDRVNVVSPLGTELGPIGPIPKSRAFRVAAIFYSGMYEYDSKFVYILLKEAQDFFDM
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHC
KGATGIELKVADIDDARRIASQVVKALGGYPYRARDWGEMNKNFFSALRLQKLVMGIILS
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIIIVAAGLIVATVIMLVLEKRKEISVLKALGVPDGGIVKIFLAEGLQIGVAGGLLGLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHH
GLSSCFFIEKVGIKLDPGVYFMSALPVRIEPVQTVLAVVIAVLVTYLASIYPALKASSVE
HHHHHHHHHHCCCEECCCCCEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVEGLKAE
CCCCCCCC
>Mature Secondary Structure
MRSAERQTVYRWTFIWMGALVALAGFALLGVALTSAHAWEEASPALGLSLLGWGGLVQAL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
NAALLVSRQAVAPLPNTGVLLAGTAVWLVGWGLIAAGIRRAPASTEGPSPAAGATLYPRL
HHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHH
ARYRDFYWSTLGAYGGGILLSEVVLILLQTVLSSGGATNELAGTAKGGGGLSLAPTGAFA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEECCHHHHH
IALMAGGMVAFISGFIGASRAQRLSLPEATIGVLYLGLPIPIVLTLMERLPGLQLALGYR
HHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHCCCCEEHHHHH
LREVTYVAGLIGRPELGYWLVFMFLVLALVLGVNTGFIAAGSGRVDLKMGFELFVARRHV
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHHHHHHHHHHHH
AVFRPSLLLGTLAVLMLGIIPPLLIYFIIRSAEAAVERTRIRKLGLKDPLAAASDLNRLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
QHEQSPTMMMTALSVGGVGVGVMALIIVLSVMSGFEADLQQKILGTNAHAVVSKYAGDLP
HHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHCCCH
EYAKVMESVRKVPGVVGQTPFIINQVMIASEGNVDGVIIKGIDPGTVGEVTDLPKNILGG
HHHHHHHHHHHCCCCCCCCCHHHHHEEEECCCCCCEEEEECCCCCCCCCHHHCCHHHCCC
GSLDTLYTPEKIVHRGLPDEEPAEEGGVEEDEIIRRSGTPKKPQVLPGIVIGRELAASLR
CCCCCCCCCHHHHHCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
VVVGDRVNVVSPLGTELGPIGPIPKSRAFRVAAIFYSGMYEYDSKFVYILLKEAQDFFDM
HHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHC
KGATGIELKVADIDDARRIASQVVKALGGYPYRARDWGEMNKNFFSALRLQKLVMGIILS
CCCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IIIIVAAGLIVATVIMLVLEKRKEISVLKALGVPDGGIVKIFLAEGLQIGVAGGLLGLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHH
GLSSCFFIEKVGIKLDPGVYFMSALPVRIEPVQTVLAVVIAVLVTYLASIYPALKASSVE
HHHHHHHHHHCCCEECCCCCEECCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVEGLKAE
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]