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The map label for this gene is hup [H]

Identifier: 108757022

GI number: 108757022

Start: 1691407

End: 1691676

Strand: Reverse

Name: hup [H]

Synonym: MXAN_1434

Alternate gene names: 108757022

Gene position: 1691676-1691407 (Counterclockwise)

Preceding gene: 108761962

Following gene: 108759427

Centisome position: 18.51

GC content: 59.63

Gene sequence:

>270_bases
ATGACCAAGGCAGAACTCGTCGAGGTGGTGGCGGCGCAGACACGTCTCACCAAGAAGTCGGCGGCGCAGATCCTCGACAT
CGTCTTCACCAATATCGGTAAGGCGGTGAAGAAGGACGCCCGCTTCAGCTATCCCGGCTTTGGAACCTGGTCGGTTCGGT
CGCGCAAGGCTCGCAAGATTCGCAACCCCCAGACCAACGAGATGATGAAGCTCAAGGCGTCGAAGACGATCGGCTTCCGG
CCCGCCAAGGAGCTGAAGAACTCCCTCTAG

Upstream 100 bases:

>100_bases
CGGCTCCAAACCGCAGCCGGCATTGACAGGGAAAAGAGCGATTTGTTACCACCAGCCGGGTTAAAGCACTTCAAGGCCAG
ACAACGGACGGAGGGGCGTA

Downstream 100 bases:

>100_bases
GCCATCGCCGAGGGACTTCGCGCAGGGGCGCTCACCCGAAAGGGGGCGCCCCTGTTGCATTGCGGGCTAGCGGCTTACGG
GCCCACGGGCCACTGACGGC

Product: DNA-binding protein HU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 89; Mature: 88

Protein sequence:

>89_residues
MTKAELVEVVAAQTRLTKKSAAQILDIVFTNIGKAVKKDARFSYPGFGTWSVRSRKARKIRNPQTNEMMKLKASKTIGFR
PAKELKNSL

Sequences:

>Translated_89_residues
MTKAELVEVVAAQTRLTKKSAAQILDIVFTNIGKAVKKDARFSYPGFGTWSVRSRKARKIRNPQTNEMMKLKASKTIGFR
PAKELKNSL
>Mature_88_residues
TKAELVEVVAAQTRLTKKSAAQILDIVFTNIGKAVKKDARFSYPGFGTWSVRSRKARKIRNPQTNEMMKLKASKTIGFRP
AKELKNSL

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=33.7078651685393, Blast_Score=65, Evalue=9e-13,
Organism=Escherichia coli, GI1788005, Length=87, Percent_Identity=31.0344827586207, Blast_Score=60, Evalue=2e-11,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9997; Mature: 9866

Theoretical pI: Translated: 11.60; Mature: 11.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAELVEVVAAQTRLTKKSAAQILDIVFTNIGKAVKKDARFSYPGFGTWSVRSRKARKI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
RNPQTNEMMKLKASKTIGFRPAKELKNSL
CCCCCHHHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
TKAELVEVVAAQTRLTKKSAAQILDIVFTNIGKAVKKDARFSYPGFGTWSVRSRKARKI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
RNPQTNEMMKLKASKTIGFRPAKELKNSL
CCCCCHHHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]