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The map label for this gene is plsC [H]

Identifier: 108563720

GI number: 108563720

Start: 1340033

End: 1340749

Strand: Reverse

Name: plsC [H]

Synonym: HPAG1_1295

Alternate gene names: 108563720

Gene position: 1340749-1340033 (Counterclockwise)

Preceding gene: 108563721

Following gene: 108563719

Centisome position: 83.99

GC content: 39.61

Gene sequence:

>717_bases
ATGAAGTCAAATAAAAAATCTTTAAGAGCGATTTATAGAGCTTTAGTGATCGCTATAGGACTAGCTGCTATCATTGTTTT
CAATTATTTTAACCGCAAAAACAATAACGCCCGCTCCAGCCGTAGGGCTTGTTCGTGCTTTTTTCCCCTTACCGGGGTTA
ATTTAGAAAAAATAGGCGCTTTTGATACGGACGCTAAACTCATTGTCTTAAACCACCAAAGCTTACTAGACATTATTTAT
TTAGAAGCCTACCACCCTAGCAATATTTGTTGGATCGCTAAAAAAGAGCTAGGCGAAATCCCTTTTTATGGGCATGCCTT
AACGGATACGGGAATGATTTTAATTGACAGGGAGGATAAAAAGGGGATTGTGAGCCTTTTGAAAGCGTGTAAGGAAAAGC
TAGATCAAAACCGCCCTTTAGTGATTTTCCCTGAAGGCACTAGAGGCAAAGGAGGAGAAAAATTCCTCCCTTTCAAGCAA
GGGGCTAAAATCATCGCCGAAAAATTCCAGCTCAAAATCCAGCCCATGGTGTTAATCAATTCCATTAAAATCTTTAATTC
CAAACCCCTAGAAGCCTATAAAGCCCGCACCCGTTTAGTCATGCTAGAAAGCTATACGCCTAATTTTAACTCGCCCACCT
GGTATGAAGAATTACAAGAACGCATGCAAAAAGAGTATTTAAAACACTATCATGAATTAAACCCTAGCGAACAATGA

Upstream 100 bases:

>100_bases
GGGCTTTCTAAAAATGAAATGCCGATTAAAATCTTAGGCTCGCATGATGATTATTATAAAATCCTAACGCCGCATGAACA
AATAGGATGGGTCAAAAAAG

Downstream 100 bases:

>100_bases
AGCTTTTTGACTACGCTCCTTTGAGTTTGGCTTGGCGGGAATTTTTGCAAAGCGAATTTAAAAAGCCTTATTTTTTAGAA
ATAGAAAAACGCTACCTAGA

Product: 1-acyl-glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: 1-AGP acyltransferase; 1-AGPAT; Lysophosphatidic acid acyltransferase; LPAAT [H]

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MKSNKKSLRAIYRALVIAIGLAAIIVFNYFNRKNNNARSSRRACSCFFPLTGVNLEKIGAFDTDAKLIVLNHQSLLDIIY
LEAYHPSNICWIAKKELGEIPFYGHALTDTGMILIDREDKKGIVSLLKACKEKLDQNRPLVIFPEGTRGKGGEKFLPFKQ
GAKIIAEKFQLKIQPMVLINSIKIFNSKPLEAYKARTRLVMLESYTPNFNSPTWYEELQERMQKEYLKHYHELNPSEQ

Sequences:

>Translated_238_residues
MKSNKKSLRAIYRALVIAIGLAAIIVFNYFNRKNNNARSSRRACSCFFPLTGVNLEKIGAFDTDAKLIVLNHQSLLDIIY
LEAYHPSNICWIAKKELGEIPFYGHALTDTGMILIDREDKKGIVSLLKACKEKLDQNRPLVIFPEGTRGKGGEKFLPFKQ
GAKIIAEKFQLKIQPMVLINSIKIFNSKPLEAYKARTRLVMLESYTPNFNSPTWYEELQERMQKEYLKHYHELNPSEQ
>Mature_238_residues
MKSNKKSLRAIYRALVIAIGLAAIIVFNYFNRKNNNARSSRRACSCFFPLTGVNLEKIGAFDTDAKLIVLNHQSLLDIIY
LEAYHPSNICWIAKKELGEIPFYGHALTDTGMILIDREDKKGIVSLLKACKEKLDQNRPLVIFPEGTRGKGGEKFLPFKQ
GAKIIAEKFQLKIQPMVLINSIKIFNSKPLEAYKARTRLVMLESYTPNFNSPTWYEELQERMQKEYLKHYHELNPSEQ

Specific function: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position [H]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI15100175, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=155, Percent_Identity=32.258064516129, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320151, Length=151, Percent_Identity=31.7880794701987, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364648, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582856, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582854, Length=168, Percent_Identity=30.3571428571429, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR004552 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.51 [H]

Molecular weight: Translated: 27357; Mature: 27357

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSNKKSLRAIYRALVIAIGLAAIIVFNYFNRKNNNARSSRRACSCFFPLTGVNLEKIGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEECCCCCCCHHHCCC
FDTDAKLIVLNHQSLLDIIYLEAYHPSNICWIAKKELGEIPFYGHALTDTGMILIDREDK
CCCCCEEEEEECHHHEEEHEEEEECCCCEEEEEHHHCCCCCCCCEEECCCCEEEEECCCC
KGIVSLLKACKEKLDQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAEKFQLKIQPMVLIN
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEE
SIKIFNSKPLEAYKARTRLVMLESYTPNFNSPTWYEELQERMQKEYLKHYHELNPSEQ
EEEECCCCCHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKSNKKSLRAIYRALVIAIGLAAIIVFNYFNRKNNNARSSRRACSCFFPLTGVNLEKIGA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEEEECCCCCCCHHHCCC
FDTDAKLIVLNHQSLLDIIYLEAYHPSNICWIAKKELGEIPFYGHALTDTGMILIDREDK
CCCCCEEEEEECHHHEEEHEEEEECCCCEEEEEHHHCCCCCCCCEEECCCCEEEEECCCC
KGIVSLLKACKEKLDQNRPLVIFPEGTRGKGGEKFLPFKQGAKIIAEKFQLKIQPMVLIN
HHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHEECEEEEEE
SIKIFNSKPLEAYKARTRLVMLESYTPNFNSPTWYEELQERMQKEYLKHYHELNPSEQ
EEEECCCCCHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9252185 [H]