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The map label for this gene is rpoBC [H]

Identifier: 108563562

GI number: 108563562

Start: 1199313

End: 1207985

Strand: Reverse

Name: rpoBC [H]

Synonym: HPAG1_1137

Alternate gene names: 108563562

Gene position: 1207985-1199313 (Counterclockwise)

Preceding gene: 108563563

Following gene: 108563561

Centisome position: 75.67

GC content: 43.48

Gene sequence:

>8673_bases
ATGTCAAAAAAAATTCCCCTAAAAAACCGCTTGAGAGCTGATTTTACAAAAACCCCGACAGATTTAGAAGTTCCTAATTT
ATTATCATTACAACGAGACAGCTATGATTCTTTCTTGTATTCCAAAGATGGCAAAGAGAGCGGGATTGAAAAGGTTTTTA
AATCCATTTTCCCTATCCAAGATGAGCATAACCGTATCACTTTAGAATACGCAGGTTGCGAATTTGGCAAGTCTAAATAC
ACTGTTAGAGAAGCGATGGAGAGAGGCATTACCTACTCTATCCCCCTCAAAATTAAAGTGCGCTTGATCTTGTGGGAAAA
AGACACCAAGAGTGGCGAAAAGAACGGCATTAAGGATATTAAAGAACAAAGCATTTTCATTCGTGAGATCCCTTTGATGA
CAGAACGCACTTCATTTATTATCAATGGGGTGGAGCGCGTGGTGGTCAATCAACTCCACAGAAGCCCCGGTGTGATTTTC
AAAGAAGAGGAGTCTAGCACTTCTTTAAACAAGCTCATTTACACAGGGCAAATCATCCCTGATAGGGGTTCGTGGTTGTA
TTTTGAATACGATTCTAAAGATGTTTTGTATGCTCGTATCAACAAACGCCGTAAAGTGCCTGTTACCATTTTATTCAGGG
CGATGGATTATCAAAAACAAGACATCATTAAAATGTTCTACCCGCTTGTTAAAGTGCGTTATGAAAACGATAAATATTTG
ATCCCGTTTGCTTCATTAGACGCCAATCAAAGAATGGAATTTGACTTGAAAGATTCACAAGGCAAGATCATTCTTTTAGC
GGGTAAAAAGCTCACTTCAAAAAAGATTAAAGAGCTTAAAGAAAACCATCTAGAATGGGTGGAATACCCTATGGATATTT
TAATCAATCGCCATTTAGCTGAGCCTGTTATGGTGGGGAAAGAAGTCTTATTGGACATGCTCACTCAGCTAGATAAAAAC
AAATTAGAAAAAATCCACGATTTAGGCGTGCAAGAATTTGTGATCATCAACGATCTAGCGTTAGGGCATGACGCTTCCAT
TATCCATTCTTTTTTGGCCGATTATGAGTCTTTGAGATTACTCAAGCAAACCGAAAAAATTGATGATGAAAACGCTCTAG
CGGCGATTCGTATCCATAAGGTTATGAAACCAGGCGATCCTGTTACGACTGAAGTGGCTAAGCAGTTTGTCAAAAAACTT
TTCTTTGATCCAGAACGCTATGATTTGACCATGGTGGGGCGCATGAAAATGAATCACAAGTTAGGCTTGCATGTGCCTGA
TTACATCACGACTTTAACGCATGAAGATATTATCACCACCGTTAAATACCTCATGAAAATCAAAAACAATCAGGGCAAGA
TTGATGATAGGGATCACTTGGGCAATCGTAGGATCAGAGCGGTAGGGGAATTATTGGCTAATGAATTGCATTCAGGCTTA
GTGAAAATGCAAAAGACCATTAAAGACAAGCTCACTACCATGAGTGGGGCTTTTGATTCGCTCATGCCCCATGACTTGGT
CAATTCTAAAATGATCACAAGCACCATCATGGAATTTTTCATGGGCGGTCAGCTCTCGCAATTTATGGATCAAACGAACC
CCTTGAGTGAGGTTACGCACAAACGCCGCCTTTCAGCACTCGGTGAAGGGGGGTTGGTGAAAGACAGGGTAGGGTTTGAA
GCTAGGGATGTGCACCCCACGCATTATGGCCGAATTTGTCCCATTGAGACCCCAGAAGGTCAAAATATCGGTTTGATCAA
CACCCTTTCCACTTTCACGAGAGTGAATGATTTAGGCTTTATTGAAGCCCCTTATAAAAAGGTTGTGGATGGCAAGGTAG
TGGGTGAGACGATTTATTTGACCGCTATTCAAGAAGACAGCCACATCATCGCTCCCGCAAGCACCCCCATTGATGAAGAG
GGTAATATTTTGGGCGATTTGATTGAAACGCGCGTGGAAGGCGAAATCGTTTTAAACGAAAAAAGCAAAGTTACCTTAAT
GGATTTAAGCTCTAGCATGCTAGTAGGGGTCGCCGCATCGCTCATTCCTTTCTTAGAGCATGATGACGCCAACCGCGCCT
TAATGGGGACTAACATGCAGCGCCAAGCGGTGCCTTTATTAAGAAGCGACGCTCCCATTGTAGGCACAGGGATTGAAAAA
ATTATCGCTAGGGATTCTTGGGGAGCGATCAAAGCCAATCGTGCAGGCGCTGTAGAAAAAATTGATTCTAAAAATATTTA
CATTTTAGGCGAAGGCAAAGAAGAAGCCTATATTGATGCGTATTCTTTGCAAAAAAACTTGCGCACCAACCAAAACACCA
GTTTCAATCAAGTCCCTATCGTTAAAGTGGGCGATAAAGTGGAAGCCGGGCAAATCATCGCTGATGGCCCTAGCATGGAT
AGGGGCGAGTTAGCGTTAGGGAAAAACGTGCGCGTGGCGTTCATGCCTTGGAATGGCTATAACTTTGAAGACGCCATCGT
GGTGAGTGAACGCATCACTAAAGACGATATTTTCACTTCCACCCACATTTATGAAAAAGAAGTGGACGCTAGGGAGCTTA
AGCATGGCGTGGAAGAATTTACCGCTGATATTCCTGATGTGAAAGAAGAAGCGCTCGCTCATCTTGATGAAAGCGGGATC
GTTAAAGTGGGCACTTATGTGAGTGCTGGCATGATTTTAGTGGGCAAGACTTCTCCTAAAGGCGAGATTAAAAGCACGCC
TGAAGAACGGCTTTTAAGGGCTATTTTTGGGGATAAAGCTGGGCATGTGGTCAATAAGAGTTTGTATTGCCCCCCCAGTT
TGGAAGGCACGGTGATTGATGTGAAAGTCTTCACTAAAAAAGGCTATGAGAAGGATGCGCGAGTTTTGAGCGCGTATGAA
GAAGAAAAAGCCAAGCTTGATATGGAGCATTTTGATCGCTTGACCATGCTCAATAGAGAAGAATTGTTGCGCGTTAGTTC
GCTCCTTTCTCAAGCGATTTTAGAAGAGCCTTTCAGCCATAACGGCAAGGATTATAAAGAAGGCGATCAAATCCCTAAAG
AAGAAATCGCTTCAATCAACCGCTTCACTTTGGCCAGTTTGGTGAAAAAGTATTCTAAAGAAGTGCAAAACCACTATGAA
ATCACTAAAAACAATTTCTTAGAGCAAAAGAAAGTTTTGGGCGAAGAGCATGAAGAAAAGCTTTCTATTTTAGAAAAAGA
TGATATTTTGCCTAATGGCGTGATCAAAAAAGTCAAGCTCTATATCGCTACAAAACGAAAGCTTAAAGTGGGCGATAAAA
TGGCAGGAAGGCATGGGAATAAAGGGATTGTGTCTAATATCGTGCCGGTTGCGGATATGCCTTATACCGCTGATGGCGAG
CCTGTGGATATTGTCTTAAACCCTTTAGGCGTGCCAAGCCGCATGAATATCGGGCAGATTTTAGAAATGCATTTAGGCTT
AGTGGGGAAAGAATTTGGGAAGCAAATCGCTCGCATGCTAGAGGATAAAACCAAAGATTTTGCCAAAGAATTGCGCGTTA
AAATGCTAGAAATCGCTAACGCCATTAATGAAAAAGACCCTTTGACAATCCATGCGCTTGAGAATTGTTCTGATGAAGAG
CTTTTGGAATACGCTAAAGATTGGAGCAAGGGCGTTAAGATGGCTATCCCTGTGTTTGAAGGCATCTCGCAAGAAAAATT
TTACAAGCTATTTGAATTAGCCAAGATCGCTATGGATGGCAAAATGGATCTGTATGACGGGCGTACAGGCGAAAAAATGA
GGGAGCGCGTGAATGTGGGCTACATGTATATGATCAAACTCCACCACTTAGTGGATGAAAAAGTCCATGCCAGAAGCACA
GGCCCTTATAGCTTAGTAACGCACCAGCCTGTTGGGGGTAAAGCGCTCTTTGGGGGTCAAAGGTTTGGGGAAATGGAAGT
GTGGGCCTTGGAAGCTTATGGCGCAGCGCACACTCTAAAAGAAATGCTCACCATTAAATCCGATGATATTAGAGGCAGAG
AGAACGCTTATAGGGCTATCGTTAAAGGTGAGCAAGTGGGCGAGAGTGAAATCCCTGAGACTTTCTATGTCTTGACTAAA
GAATTGCAATCGCTCGCTTTGGATATTAATATTTTTGGGGACGATGTGGATGAGGATGGAGCGCCTAAACCCATTGTCAT
TAAAGAAGATGACAGGCCTAAAGACTTTAGCTCTTTCCAACTCACTCTAGCCAGCCCTGAAAAAATCCATTCTTGGAGTT
ATGGGGAAGTTAAAAAGCCAGAAACGATCAATTATCGCACTCTAAAACCTGAACGAGACGGCTTGTTTTGCATGAAAATC
TTTGGCCCCACTAAAGATTATGAATGCTTGTGCGGTAAATACAAAAAGCCTCGCTTCAAAGACATTGGCACATGCGAAAA
ATGCGGCGTGGCGATCACGCACTCCAAAGTCAGGCGTTTTAGAATGGGGCATATTGAATTGGCCACTCCTGTAGCGCATA
TTTGGTATGTTAATTCCTTGCCTAGCCGTATCAGCACGCTTTTAGGCGTTAAGATGAAAGACTTAGAGCGCGTGTTGTAT
TATGAAGCTTATATCGTTAAAGAACCAGGCGAAGCCGCTTATGACAATGAAGGCACTAAGCTTGTGATGAAATACGATAT
TTTGAATGAAGAGCAGTATCAAAATATCTCACGAAGATACGAAGACAGGGGCTTTATAGCACAAATGGGCGGCGAAGCGA
TCAAGGATTTGTTAGAAGAAATTGATTTGATCACCTTATTGCAGAGTTTGAAAGAAGAAGTGAAAGACACCAATTCCGAT
GCGAAAAAGAAAAAACTCATTAAGCGTTTGAAAGTGGTAGAAAGCTTTTTAAATTCTGGTAACAGACCTGAGTGGATGAT
GCTCACGGTTTTACCGGTATTGCCGCCGGATTTAAGGCCTTTAGTCGCGCTAGATGGCGGGAAGTTTGCGGTCAGCGATG
TGAATGAATTGTATCGTCGTGTTATTAATCGTAACCAACGCTTGAAACGCTTGATGGAGCTTGGAGCGCCAGAAATCATT
GTGCGCAATGAAAAAAGGATGTTGCAAGAAGCCGTGGATGTGCTTTTTGATAACGGTCGCAGCACCAATGCGGTTAAAGG
GGCTAACAAACGCCCTTTAAAATCGCTCAGCGAGATCATTAAAGGCAAGCAAGGGCGTTTCAGGCAAAACCTTTTAGGTA
AGCGCGTGGATTTTTCAGGCAGAAGCGTGATTGTGGTTGGGCCTAACCTTAAAATGGATGAATGCGGGTTGCCTAAAAAC
ATGGCGTTAGAACTCTTTAAACCGCATTTGTTATCCAAGCTTGAAGAGAGAGGCTATGCCACCACGCTCAAACAAGCTAA
ACGCATGATTGAACAAAAAAGCAATGAAGTGTGGGAGTGCTTGCAAGAAATCACAGAGGGGTATCCGGTGTTACTCAACC
GCGCTCCTACCTTGCACAAGCAATCCATTCAAGCGTTCCATCCAAAGCTGATTGATGGCAAAGCGATCCAATTGCACCCG
TTAGTGTGTTCAGCGTTTAACGCCGATTTTGACGGGGACCAAATGGCGGTGCATGTGCCTTTAAGCCAGGAAGCGATCGC
TGAATGCAAGGTGCTGATGCTAAGCTCTATGAATATCCTTCTGCCCGCTAGCGGTAAAGCCGTAGCCATTCCTAGCCAGG
ATATGGTTTTAGGGCTTTATTATCTTTCTTTAGAAAAGAGCGGGGTCAAGGGCGAGCATAAGCTTTTTTCTAGCGTGAAT
GAAATCATCACCGCTATTGACACGAAAGAATTAGACATCCACGCAAAGATTAGGGTTTTAGATCAAGGGAATATTATCGC
TACGAGCGCGGGGCGCATGATCATTAAGTCTATTTTGCCTGATTTTATCCCTACGGATTTGTGGAACAGACCCATGAAGA
AAAAAGATATTGGTGTGCTTGTGGATTATGTGCATAAAGTCGGTGGTATCGGCATTACCGCAACCTTTTTGGATAATTTG
AAAACGCTTGGCTTTAGGTATGCGACTAAGGCTGGTATTTCTATCTCTATGGAAGATATTATCACGCCAAAAGACAAGCA
AAAAATGGTGGAAAAAGCCAAAGTAGAGGTTAAAAAAATCCAGCAACAATACGATCAAGGGCTACTCACTGACCAAGAGC
GTTACAATAAAATCATTGACACTTGGACTGAAGTCAATGACAAAATGAGTAAAGAAATGATGATCGCTATCGCAAAAGAT
AAAGAGGGCTTTAACTCTATTTATATGATGGCAGATAGCGGTGCAAGGGGTAGCGCGGCGCAAATCCGTCAGCTTTCAGC
GATGAGGGGTCTTATGACAAAGCCGGACGGCAGCATCATTGAAACGCCCATTATTTCTAACTTTAAAGAGGGGTTGAATG
TCTTAGAATACTTTAACTCCACGCATGGCGCTAGAAAGGGCTTAGCGGATACTGCGCTAAAAACAGCCAATGCGGGGTAT
TTGACAAGAAAACTCATTGATGTTTCGCAAAATGTCAAGGTGGTGTCTGATGATTGCGGCACGCATGAAGGGATTGAAAT
CACGGATATTGCGGTGGGGAGTGAGCTGATTGAACCTTTAGAAGAGCGTATTTTTGGGCGCGTTTTATTAGAAGATGTGA
TCGATCCCATTACGAATGAAATCTTGCTTTATGCGGACACTTTGATTGATGAAGAGGGCGCTAAAAAGGTGGTTGAAGCC
GGGATTAAATCCATTACGATCCGCACCCCAGTAACTTGTAAAGCGCCAAAGGGCGTGTGCGCGAAATGCTATGGCTTGAA
TTTGGGCGAAGGCAAGATGAGCTATCCAGGTGAAGCGGTGGGCGTGGTAGCCGCGCAATCTATTGGGGAGCCTGGAACGC
AGCTCACTTTAAGGACTTTCCATGTGGGCGGAACAGCGAGCAGGAGTCAGGATGAGCGCGAAATTGTAGCGAGCAAAGAA
GGTTTTGTGCGTTTTTATAACCTTAGGACTTACACGAACAAAGAGGGTAAAAACATTATCGCTAACCGCCGTAACGCTTC
TATTTTAGTGGTAGAGCCTAAGATTAAAGCGCCTTTTGATGGGGAATTACGCATTGAAACGGTCTATGAAGAAGTCGTTG
TGAGCGTGAAAAATGGCGAGCAAGAAGCTAAGTTCGTTTTAAGAAGAAGCGATATTGTCAAGCCAAGCGAATTAGCCGGC
GTTGGCGGTAAGATTGAGGGGAAAGTGTATTTGCCTTATGCTAGTGGGCATAAGGTGCATAAGGGGGGAAGTATCGCTGA
TATTATCCAAGAGGGTTGGAATGTGCCTAATCGCATCCCTTATGCGAGCGAATTGCTAGTCAAGGATAATGACCCTATTG
CACAAGATGTGTATGCCAAAGAAAAAGGCACAATCAAATACTATGTTTTAGAGGCTAACCATTTGGAGCGCACCCATGGG
ATCAAAAAGGGCGATATGGTGAGCGAAAAAGGCTTGTTTGCGGTGGTAGCTGATGATAATGGTAGGGAAGCCGCTCGCCA
TTATATCGCTAGGGGTTCTGAGATCTTGATTGATGATAATAGTGAAGTGAGCGCTAATAGCGTGATCTCTAAACTCACGA
CTAACACTTTCAAAACGATTGCCACATGGGATCCTTACAACACCCCTATCATTGCGGACTTTAAAGGTAAGGTGAGTTTT
GTGGATGTTATCGCAGGGGTTACGGTCGCTGAAAAAGAAGACGAAAATACCGGTATCACCAGTTTAGTGGTGAATGATTA
CATCCCAAGCGGATACAAACCAAGCTTGTTTTTAGAGGGGGCTAATGGCGAAGAGATGCGTTATTTCCTAGAGCCAAAAA
CTTCTATCGCCATTAGCGATGGCTCTAGCGTGGAGCAGGCTGAAGTGTTAGCGAAAATCCCTAAAGCGACCGTTAAATCC
AGGGATATTACTGGGGGTCTCCCAAGGGTTTCTGAACTCTTTGAAGCGAGAAAACCCAAGCCTAAAGATGTGGCGATCCT
TTCTGAAGTGGATGGGATTGTGAGTTTTGGCAAACCCATTCGCAATAAAGAACACATCATCGTAACTTCTAAAGATGGCC
GTTCCATGGATTATTTTGTGGATAAAGGCAAGCAAATTCTAGTGCATGCTGATGAATTTGTGCATGCAGGAGAGGCGATG
ACGGATGGAGTAATTTCAAGCCATGATATTTTAAGGATCAGCGGCGAAAAAGAGCTTTATAAATACATTGTGAGCGAAGT
CCAGCAAGTGTATCGCAGGCAGGGGGTAAGCATTGCCGACAAGCACATTGAAATCATTGTTTCTCAAATGCTAAGGCAAG
TGCGTATTTTAGACAGCGGGGATAGCAAGTTTATTGAAGGGGATTTAGTCAGTAAAAAACTCTTCAAAGAAGAAAACGCT
CGTATGATCGCTTTAAAAGGCGAGCCAGCGATTGCTGAACCGGTGCTTTTAGGGATCACCAGAGCGGCTATCGGGAGCGA
TAGCATCATTTCAGCGGCCTCTTTCCAAGAAACGACTAAAGTTTTAACAGAAGCCAGTATCGCTATGAAAAAAGACTTTT
TAGAAGACTTGAAAGAGAATGTGGTGTTGGGGAGGATGATCCCTGTGGGAACGGGCATGTATAAGAATAAAAAAATCGTG
CTGAGAACGCTTGAAGATGGCCCTAAATTTTGA

Upstream 100 bases:

>100_bases
ATGGATTCATGGATGGTTCTAAAGTTTAAAGATCCTTTTGCAATGCTTACTTGAATTAATGCATTAAATAACTCAAAATT
TTTGATCAAAGGCTTGAAAT

Downstream 100 bases:

>100_bases
TATAAAAAATCGGTTAAGATTTTTAAAAGAAAAATTAGGGTAAAATGGGGGAACTTTTAGTTTTAAATTTTTAGAATAAG
GAAAAATAGTGCCTACTATC

Product: DNA-directed RNA polymerase subunit beta/beta'

Products: NA

Alternate protein names: DNA-directed RNA polymerase subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta; DNA-directed RNA polymerase subunit beta'; RNA polymerase beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 2890; Mature: 2889

Protein sequence:

>2890_residues
MSKKIPLKNRLRADFTKTPTDLEVPNLLSLQRDSYDSFLYSKDGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKY
TVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIF
KEEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
IPFASLDANQRMEFDLKDSQGKIILLAGKKLTSKKIKELKENHLEWVEYPMDILINRHLAEPVMVGKEVLLDMLTQLDKN
KLEKIHDLGVQEFVIINDLALGHDASIIHSFLADYESLRLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKL
FFDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFE
ARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEE
GNILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
IIARDSWGAIKANRAGAVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQVPIVKVGDKVEAGQIIADGPSMD
RGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGI
VKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYE
ITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGE
PVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIARMLEDKTKDFAKELRVKMLEIANAINEKDPLTIHALENCSDEE
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARST
GPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIVKGEQVGESEIPETFYVLTK
ELQSLALDINIFGDDVDEDGAPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRISTLLGVKMKDLERVLY
YEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFIAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSD
AKKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKN
MALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHP
LVCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNL
KTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMIAIAKD
KEGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEA
GIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKE
GFVRFYNLRTYTNKEGKNIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGEQEAKFVLRRSDIVKPSELAG
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGTIKYYVLEANHLERTHG
IKKGDMVSEKGLFAVVADDNGREAARHYIARGSEILIDDNSEVSANSVISKLTTNTFKTIATWDPYNTPIIADFKGKVSF
VDVIAGVTVAEKEDENTGITSLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFVDKGKQILVHADEFVHAGEAM
TDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENA
RMIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
LRTLEDGPKF

Sequences:

>Translated_2890_residues
MSKKIPLKNRLRADFTKTPTDLEVPNLLSLQRDSYDSFLYSKDGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKY
TVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIF
KEEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
IPFASLDANQRMEFDLKDSQGKIILLAGKKLTSKKIKELKENHLEWVEYPMDILINRHLAEPVMVGKEVLLDMLTQLDKN
KLEKIHDLGVQEFVIINDLALGHDASIIHSFLADYESLRLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKL
FFDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFE
ARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEE
GNILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
IIARDSWGAIKANRAGAVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQVPIVKVGDKVEAGQIIADGPSMD
RGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGI
VKVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYE
ITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGE
PVDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIARMLEDKTKDFAKELRVKMLEIANAINEKDPLTIHALENCSDEE
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARST
GPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIVKGEQVGESEIPETFYVLTK
ELQSLALDINIFGDDVDEDGAPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRISTLLGVKMKDLERVLY
YEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFIAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSD
AKKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKN
MALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHP
LVCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNL
KTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMIAIAKD
KEGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEA
GIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKE
GFVRFYNLRTYTNKEGKNIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGEQEAKFVLRRSDIVKPSELAG
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGTIKYYVLEANHLERTHG
IKKGDMVSEKGLFAVVADDNGREAARHYIARGSEILIDDNSEVSANSVISKLTTNTFKTIATWDPYNTPIIADFKGKVSF
VDVIAGVTVAEKEDENTGITSLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFVDKGKQILVHADEFVHAGEAM
TDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENA
RMIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
LRTLEDGPKF
>Mature_2889_residues
SKKIPLKNRLRADFTKTPTDLEVPNLLSLQRDSYDSFLYSKDGKESGIEKVFKSIFPIQDEHNRITLEYAGCEFGKSKYT
VREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDIKEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFK
EEESSTSLNKLIYTGQIIPDRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYLI
PFASLDANQRMEFDLKDSQGKIILLAGKKLTSKKIKELKENHLEWVEYPMDILINRHLAEPVMVGKEVLLDMLTQLDKNK
LEKIHDLGVQEFVIINDLALGHDASIIHSFLADYESLRLLKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLF
FDPERYDLTMVGRMKMNHKLGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGLV
KMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTHKRRLSALGEGGLVKDRVGFEA
RDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGFIEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEG
NILGDLIETRVEGEIVLNEKSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEKI
IARDSWGAIKANRAGAVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQVPIVKVGDKVEAGQIIADGPSMDR
GELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTSTHIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIV
KVGTYVSAGMILVGKTSPKGEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYEE
EKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASINRFTLASLVKKYSKEVQNHYEI
TKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKLYIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEP
VDIVLNPLGVPSRMNIGQILEMHLGLVGKEFGKQIARMLEDKTKDFAKELRVKMLEIANAINEKDPLTIHALENCSDEEL
LEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVGYMYMIKLHHLVDEKVHARSTG
PYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLKEMLTIKSDDIRGRENAYRAIVKGEQVGESEIPETFYVLTKE
LQSLALDINIFGDDVDEDGAPKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKIF
GPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSLPSRISTLLGVKMKDLERVLYY
EAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRYEDRGFIAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDA
KKKKLIKRLKVVESFLNSGNRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEIIV
RNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSGRSVIVVGPNLKMDECGLPKNM
ALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWECLQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPL
VCSAFNADFDGDQMAVHVPLSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVNE
IITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVLVDYVHKVGGIGITATFLDNLK
TLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKIQQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMIAIAKDK
EGFNSIYMMADSGARGSAAQIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGYL
TRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNEILLYADTLIDEEGAKKVVEAG
IKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAVGVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEG
FVRFYNLRTYTNKEGKNIIANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGEQEAKFVLRRSDIVKPSELAGV
GGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAKEKGTIKYYVLEANHLERTHGI
KKGDMVSEKGLFAVVADDNGREAARHYIARGSEILIDDNSEVSANSVISKLTTNTFKTIATWDPYNTPIIADFKGKVSFV
DVIAGVTVAEKEDENTGITSLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKSR
DITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFVDKGKQILVHADEFVHAGEAMT
DGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIADKHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENAR
MIALKGEPAIAEPVLLGITRAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIVL
RTLEDGPKF

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=851, Percent_Identity=26.0869565217391, Blast_Score=194, Evalue=1e-48,
Organism=Homo sapiens, GI39725938, Length=314, Percent_Identity=31.2101910828025, Blast_Score=137, Evalue=1e-31,
Organism=Homo sapiens, GI103471997, Length=607, Percent_Identity=25.5354200988468, Blast_Score=120, Evalue=2e-26,
Organism=Homo sapiens, GI33469941, Length=257, Percent_Identity=30.7392996108949, Blast_Score=116, Evalue=3e-25,
Organism=Homo sapiens, GI212286172, Length=257, Percent_Identity=30.7392996108949, Blast_Score=116, Evalue=3e-25,
Organism=Homo sapiens, GI4505941, Length=169, Percent_Identity=29.585798816568, Blast_Score=81, Evalue=1e-14,
Organism=Homo sapiens, GI238908503, Length=138, Percent_Identity=36.231884057971, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI238908505, Length=138, Percent_Identity=36.231884057971, Blast_Score=74, Evalue=2e-12,
Organism=Escherichia coli, GI1790419, Length=1389, Percent_Identity=46.508279337653, Blast_Score=1222, Evalue=0.0,
Organism=Escherichia coli, GI2367335, Length=990, Percent_Identity=54.4444444444444, Blast_Score=1110, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=899, Percent_Identity=25.5839822024472, Blast_Score=187, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI25145495, Length=490, Percent_Identity=28.1632653061224, Blast_Score=145, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17552304, Length=169, Percent_Identity=29.585798816568, Blast_Score=80, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144348, Length=146, Percent_Identity=34.2465753424658, Blast_Score=77, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17506623, Length=111, Percent_Identity=36.9369369369369, Blast_Score=70, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320061, Length=890, Percent_Identity=24.9438202247191, Blast_Score=205, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6324690, Length=328, Percent_Identity=31.4024390243902, Blast_Score=140, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6324725, Length=257, Percent_Identity=31.5175097276265, Blast_Score=115, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=106, Percent_Identity=43.3962264150943, Blast_Score=81, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325267, Length=99, Percent_Identity=41.4141414141414, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17530899, Length=837, Percent_Identity=25.3285543608124, Blast_Score=178, Evalue=7e-44,
Organism=Drosophila melanogaster, GI281360912, Length=310, Percent_Identity=30.6451612903226, Blast_Score=134, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17647875, Length=357, Percent_Identity=27.4509803921569, Blast_Score=112, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136446, Length=253, Percent_Identity=30.8300395256917, Blast_Score=99, Evalue=4e-20,
Organism=Drosophila melanogaster, GI17136444, Length=169, Percent_Identity=29.585798816568, Blast_Score=81, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17647877, Length=89, Percent_Identity=42.6966292134831, Blast_Score=74, Evalue=2e-12,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR007120
- InterPro:   IPR000722
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5; PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_po

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 323867; Mature: 323736

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKIPLKNRLRADFTKTPTDLEVPNLLSLQRDSYDSFLYSKDGKESGIEKVFKSIFPIQ
CCCCCCCHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCC
DEHNRITLEYAGCEFGKSKYTVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDI
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECEEEEEEEEEEECCCCCCCCCCHHHH
KEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESSTSLNKLIYTGQIIP
HHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEEECEEEC
DRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
CCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHEEEECCCCEE
IPFASLDANQRMEFDLKDSQGKIILLAGKKLTSKKIKELKENHLEWVEYPMDILINRHLA
EEEECCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPVMVGKEVLLDMLTQLDKNKLEKIHDLGVQEFVIINDLALGHDASIIHSFLADYESLRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
LKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLFFDPERYDLTMVGRMKMNHK
HHHHHCCCCCCCEEHEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
LGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTH
HHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
KRRLSALGEGGLVKDRVGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGF
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCC
IEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEGNILGDLIETRVEGEIVLNE
CCCCHHHHCCCEEECCEEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECC
KSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHCHHHHCCCCEEECCHHH
IIARDSWGAIKANRAGAVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQVPI
HHHCCCCCCEECCCCCCHHEECCCCEEEEECCCCCCEEEHHHHHHHHCCCCCCCCCCCEE
VKVGDKVEAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTS
EEECCCCCCCEEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHCCHHHHHCC
THIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIVKVGTYVSAGMILVGKTSPK
CHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEEEEECCCCC
GEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
CCCCCCHHHHHHHHHHCCCCCCEECCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASIN
HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCH
RFTLASLVKKYSKEVQNHYEITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHEEE
YIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQI
EEEECCHHCCCCHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
LEMHLGLVGKEFGKQIARMLEDKTKDFAKELRVKMLEIANAINEKDPLTIHALENCSDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVG
HHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCC
YMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLK
EEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEHHCHHHHHH
EMLTIKSDDIRGRENAYRAIVKGEQVGESEIPETFYVLTKELQSLALDINIFGDDVDEDG
HHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
APKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
CCCCEEECCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEE
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSL
CCCCCCHHHHHCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHCCCEEECCHHHHEEEHHHH
PSRISTLLGVKMKDLERVLYYEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRY
HHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
EDRGFIAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDAKKKKLIKRLKVVESFLNSG
HCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
CCCCEEEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSG
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
RSVIVVGPNLKMDECGLPKNMALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWEC
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHH
LQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPLVCSAFNADFDGDQMAVHVP
HHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEC
LSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
CCHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVL
HHHHHHCCCEEEEEEEEEEEECCCEEEECCHHHHHHHHCHHHCCHHHHCCCCCCCHHHHH
VDYVHKVGGIGITATFLDNLKTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHH
QQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMIAIAKDKEGFNSIYMMADSGARGSAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEECCCCCCCHH
QIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCH
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNE
HHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYADTLIDEEGAKKVVEAGIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAV
EEEEHHHHHCCHHHHHHHHCCHHEEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCHH
GVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEGFVRFYNLRTYTNKEGKNII
HHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEEEECCCCCCEEE
ANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGEQEAKFVLRRSDIVKPSELAG
ECCCCCEEEEECCCCCCCCCCCEEHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCC
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAK
CCCEECCEEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHC
EKGTIKYYVLEANHLERTHGIKKGDMVSEKGLFAVVADDNGREAARHYIARGSEILIDDN
CCCCEEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECC
SEVSANSVISKLTTNTFKTIATWDPYNTPIIADFKGKVSFVDVIAGVTVAEKEDENTGIT
CCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEECCCCCHHHHHHHCCEEECCCCCCCCCE
SLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
EEEEECCCCCCCCCCEEEECCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHHCC
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFV
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHH
DKGKQILVHADEFVHAGEAMTDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIAD
CCCCEEEEECHHHHHCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHH
KHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENARMIALKGEPAIAEPVLLGIT
HHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
RAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEE
LRTLEDGPKF
EEEECCCCCC
>Mature Secondary Structure 
SKKIPLKNRLRADFTKTPTDLEVPNLLSLQRDSYDSFLYSKDGKESGIEKVFKSIFPIQ
CCCCCCHHHHCCCCCCCCCCCCCCCHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHCCCC
DEHNRITLEYAGCEFGKSKYTVREAMERGITYSIPLKIKVRLILWEKDTKSGEKNGIKDI
CCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECEEEEEEEEEEECCCCCCCCCCHHHH
KEQSIFIREIPLMTERTSFIINGVERVVVNQLHRSPGVIFKEEESSTSLNKLIYTGQIIP
HHHCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHEEEECEEEC
DRGSWLYFEYDSKDVLYARINKRRKVPVTILFRAMDYQKQDIIKMFYPLVKVRYENDKYL
CCCCEEEEEECCCCEEEEECCCCCCCCCEEEEEHHCCCHHHHHHHHHHHHEEEECCCCEE
IPFASLDANQRMEFDLKDSQGKIILLAGKKLTSKKIKELKENHLEWVEYPMDILINRHLA
EEEECCCCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EPVMVGKEVLLDMLTQLDKNKLEKIHDLGVQEFVIINDLALGHDASIIHSFLADYESLRL
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
LKQTEKIDDENALAAIRIHKVMKPGDPVTTEVAKQFVKKLFFDPERYDLTMVGRMKMNHK
HHHHHCCCCCCCEEHEEHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCC
LGLHVPDYITTLTHEDIITTVKYLMKIKNNQGKIDDRDHLGNRRIRAVGELLANELHSGL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHH
VKMQKTIKDKLTTMSGAFDSLMPHDLVNSKMITSTIMEFFMGGQLSQFMDQTNPLSEVTH
HHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHH
KRRLSALGEGGLVKDRVGFEARDVHPTHYGRICPIETPEGQNIGLINTLSTFTRVNDLGF
HHHHHHCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCC
IEAPYKKVVDGKVVGETIYLTAIQEDSHIIAPASTPIDEEGNILGDLIETRVEGEIVLNE
CCCCHHHHCCCEEECCEEEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCEEEECC
KSKVTLMDLSSSMLVGVAASLIPFLEHDDANRALMGTNMQRQAVPLLRSDAPIVGTGIEK
CCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCEEECCCCHHHHCHHHHCCCCEEECCHHH
IIARDSWGAIKANRAGAVEKIDSKNIYILGEGKEEAYIDAYSLQKNLRTNQNTSFNQVPI
HHHCCCCCCEECCCCCCHHEECCCCEEEEECCCCCCEEEHHHHHHHHCCCCCCCCCCCEE
VKVGDKVEAGQIIADGPSMDRGELALGKNVRVAFMPWNGYNFEDAIVVSERITKDDIFTS
EEECCCCCCCEEEECCCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEHHHCCHHHHHCC
THIYEKEVDARELKHGVEEFTADIPDVKEEALAHLDESGIVKVGTYVSAGMILVGKTSPK
CHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEEEEEECCEEEEECCCCC
GEIKSTPEERLLRAIFGDKAGHVVNKSLYCPPSLEGTVIDVKVFTKKGYEKDARVLSAYE
CCCCCCHHHHHHHHHHCCCCCCEECCCEECCCCCCCCEEEEEEEECCCCCHHHHHHHHHH
EEKAKLDMEHFDRLTMLNREELLRVSSLLSQAILEEPFSHNGKDYKEGDQIPKEEIASIN
HHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCH
RFTLASLVKKYSKEVQNHYEITKNNFLEQKKVLGEEHEEKLSILEKDDILPNGVIKKVKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHEEE
YIATKRKLKVGDKMAGRHGNKGIVSNIVPVADMPYTADGEPVDIVLNPLGVPSRMNIGQI
EEEECCHHCCCCHHCCCCCCCCHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHH
LEMHLGLVGKEFGKQIARMLEDKTKDFAKELRVKMLEIANAINEKDPLTIHALENCSDEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHH
LLEYAKDWSKGVKMAIPVFEGISQEKFYKLFELAKIAMDGKMDLYDGRTGEKMRERVNVG
HHHHHHHHHCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHCCC
YMYMIKLHHLVDEKVHARSTGPYSLVTHQPVGGKALFGGQRFGEMEVWALEAYGAAHTLK
EEEEHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCCCCCCEEEEEEEHHCHHHHHH
EMLTIKSDDIRGRENAYRAIVKGEQVGESEIPETFYVLTKELQSLALDINIFGDDVDEDG
HHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCC
APKPIVIKEDDRPKDFSSFQLTLASPEKIHSWSYGEVKKPETINYRTLKPERDGLFCMKI
CCCCEEECCCCCCCCCCCEEEEECCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEEE
FGPTKDYECLCGKYKKPRFKDIGTCEKCGVAITHSKVRRFRMGHIELATPVAHIWYVNSL
CCCCCCHHHHHCCCCCCCCCCCCCHHHCCEEEEHHHHHHHHCCCEEECCHHHHEEEHHHH
PSRISTLLGVKMKDLERVLYYEAYIVKEPGEAAYDNEGTKLVMKYDILNEEQYQNISRRY
HHHHHHHHCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
EDRGFIAQMGGEAIKDLLEEIDLITLLQSLKEEVKDTNSDAKKKKLIKRLKVVESFLNSG
HCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
NRPEWMMLTVLPVLPPDLRPLVALDGGKFAVSDVNELYRRVINRNQRLKRLMELGAPEII
CCCCEEEEEEECCCCCCCCCEEEECCCCEEHHHHHHHHHHHHCCCHHHHHHHHCCCCEEE
VRNEKRMLQEAVDVLFDNGRSTNAVKGANKRPLKSLSEIIKGKQGRFRQNLLGKRVDFSG
EECHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
RSVIVVGPNLKMDECGLPKNMALELFKPHLLSKLEERGYATTLKQAKRMIEQKSNEVWEC
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHH
LQEITEGYPVLLNRAPTLHKQSIQAFHPKLIDGKAIQLHPLVCSAFNADFDGDQMAVHVP
HHHHHCCCCEEECCCCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHCCCCCCCCCEEEEEC
LSQEAIAECKVLMLSSMNILLPASGKAVAIPSQDMVLGLYYLSLEKSGVKGEHKLFSSVN
CCHHHHHHHHHHHHCCCCEEEECCCCEEEECCCCCEEEEEEEEEECCCCCHHHHHHHHHH
EIITAIDTKELDIHAKIRVLDQGNIIATSAGRMIIKSILPDFIPTDLWNRPMKKKDIGVL
HHHHHHCCCEEEEEEEEEEEECCCEEEECCHHHHHHHHCHHHCCHHHHCCCCCCCHHHHH
VDYVHKVGGIGITATFLDNLKTLGFRYATKAGISISMEDIITPKDKQKMVEKAKVEVKKI
HHHHHHHCCCCEEHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHH
QQQYDQGLLTDQERYNKIIDTWTEVNDKMSKEMMIAIAKDKEGFNSIYMMADSGARGSAA
HHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCEEEEEECCCCCCCHH
QIRQLSAMRGLMTKPDGSIIETPIISNFKEGLNVLEYFNSTHGARKGLADTALKTANAGY
HHHHHHHHHCCCCCCCCCEECCHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHCCCCH
LTRKLIDVSQNVKVVSDDCGTHEGIEITDIAVGSELIEPLEERIFGRVLLEDVIDPITNE
HHHHHHHHCCCCEEEECCCCCCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLYADTLIDEEGAKKVVEAGIKSITIRTPVTCKAPKGVCAKCYGLNLGEGKMSYPGEAV
EEEEHHHHHCCHHHHHHHHCCHHEEEEECCCEECCCCCCCHHHCCCCCCCCCCCCCCCHH
GVVAAQSIGEPGTQLTLRTFHVGGTASRSQDEREIVASKEGFVRFYNLRTYTNKEGKNII
HHHHHHHCCCCCCEEEEEEEEECCCCCCCCHHHHHHHCCCCCEEEEEEEEECCCCCCEEE
ANRRNASILVVEPKIKAPFDGELRIETVYEEVVVSVKNGEQEAKFVLRRSDIVKPSELAG
ECCCCCEEEEECCCCCCCCCCCEEHHEEHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHCC
VGGKIEGKVYLPYASGHKVHKGGSIADIIQEGWNVPNRIPYASELLVKDNDPIAQDVYAK
CCCEECCEEEEEECCCCEECCCCCHHHHHHHHCCCCCCCCCHHEEEEECCCCHHHHHHHC
EKGTIKYYVLEANHLERTHGIKKGDMVSEKGLFAVVADDNGREAARHYIARGSEILIDDN
CCCCEEEEEEECCHHHHHCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEECC
SEVSANSVISKLTTNTFKTIATWDPYNTPIIADFKGKVSFVDVIAGVTVAEKEDENTGIT
CCCCHHHHHHHHHHHHHEEEEECCCCCCCEEEECCCCCHHHHHHHCCEEECCCCCCCCCE
SLVVNDYIPSGYKPSLFLEGANGEEMRYFLEPKTSIAISDGSSVEQAEVLAKIPKATVKS
EEEEECCCCCCCCCCEEEECCCCCCEEEEECCCCEEEECCCCCHHHHHHHHHCCHHHHCC
RDITGGLPRVSELFEARKPKPKDVAILSEVDGIVSFGKPIRNKEHIIVTSKDGRSMDYFV
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHH
DKGKQILVHADEFVHAGEAMTDGVISSHDILRISGEKELYKYIVSEVQQVYRRQGVSIAD
CCCCEEEEECHHHHHCCCHHHCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCHHH
KHIEIIVSQMLRQVRILDSGDSKFIEGDLVSKKLFKEENARMIALKGEPAIAEPVLLGIT
HHHHHHHHHHHHHHHHHCCCCCCEECCHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHH
RAAIGSDSIISAASFQETTKVLTEASIAMKKDFLEDLKENVVLGRMIPVGTGMYKNKKIV
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCCCCCCCEEE
LRTLEDGPKF
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA