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The map label for this gene is ttcA [H]

Identifier: 108563546

GI number: 108563546

Start: 1181684

End: 1182445

Strand: Direct

Name: ttcA [H]

Synonym: HPAG1_1121

Alternate gene names: 108563546

Gene position: 1181684-1182445 (Clockwise)

Preceding gene: 108563545

Following gene: 108563548

Centisome position: 74.02

GC content: 42.13

Gene sequence:

>762_bases
ATGGCCTATGAAATTTCTAAAAAAGTCTTACACATTGTGGGCAAGACCAACGCCACTTACAAGCTCATAGAAGAAGGCGA
TAAAATCTTATTAGGATTGAGTGGAGGCAAGGATTCTATCATGCTCGCTTGCATCTTAGCCAGGATGCAAAAACATGCCC
CTTTCAAATTTGATTTTAAAGCGGTTACCGTGCATTATGGTTTGGGCGAAGATTTGAAATGGTTGAGCGATTTGTGCCAA
GAGCAAGGCATTGAGCATGAGATCATTTACACCCAAATCGCTGCCACGATCAACGAAAAACGCCGTGAAAAAAGCTCGTT
TTGTTCGTTTTGTTCTCGTTTGAGGAGAGGGACTTTGTATTCTAAGGCTTTAGAAGAAGGCTATAATAAAGTCGCTATCG
CGCACCATTTAGATGATGCCGTAGAGAGCTTTTTTATGAATTTCACTTATAACGGGAGTTTGAGGAGCATGCCCCCCATT
TATAGGGCTGAAAACGGCTTATTGGTGATCCGCCCTTTGATTAAGGTTCGAGAAGCCAGTAGTATCCATTTTGTCACTTC
TCAAAATATCCCGGTTGCTCCTGATTGCAATTGCCCAGCCAAACAGCCTACCTCTGATAAGCCCCCTATCGCGCGATTAG
CCACTAAAAATTTCTTAAAAGAAATGCAAAACTTGCACCCTCGTTTCTTTGACAGCTTAGAAAACGCATTCAACAATGTT
CAAGCGAACAGCTTTAGCGACGCTAAATATTTAGACGCTTAA

Upstream 100 bases:

>100_bases
GAAATCATTATTGTGAAATATAATTCCGATCACATTAGCGAAGAAGAAATCATTCGCTTAGCGCAAAGCTTTAGAAAATA
AACATAATCAAGGATCAAAA

Downstream 100 bases:

>100_bases
GCTTTCATTTAAGCTTTTTTGTTGAGCATTTTAATCGCAATCGTGAATAATACCCCTTCAAAAATAGCCGCCATGAGCAA
TGCGTAGTAGGTGTTTTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MAYEISKKVLHIVGKTNATYKLIEEGDKILLGLSGGKDSIMLACILARMQKHAPFKFDFKAVTVHYGLGEDLKWLSDLCQ
EQGIEHEIIYTQIAATINEKRREKSSFCSFCSRLRRGTLYSKALEEGYNKVAIAHHLDDAVESFFMNFTYNGSLRSMPPI
YRAENGLLVIRPLIKVREASSIHFVTSQNIPVAPDCNCPAKQPTSDKPPIARLATKNFLKEMQNLHPRFFDSLENAFNNV
QANSFSDAKYLDA

Sequences:

>Translated_253_residues
MAYEISKKVLHIVGKTNATYKLIEEGDKILLGLSGGKDSIMLACILARMQKHAPFKFDFKAVTVHYGLGEDLKWLSDLCQ
EQGIEHEIIYTQIAATINEKRREKSSFCSFCSRLRRGTLYSKALEEGYNKVAIAHHLDDAVESFFMNFTYNGSLRSMPPI
YRAENGLLVIRPLIKVREASSIHFVTSQNIPVAPDCNCPAKQPTSDKPPIARLATKNFLKEMQNLHPRFFDSLENAFNNV
QANSFSDAKYLDA
>Mature_252_residues
AYEISKKVLHIVGKTNATYKLIEEGDKILLGLSGGKDSIMLACILARMQKHAPFKFDFKAVTVHYGLGEDLKWLSDLCQE
QGIEHEIIYTQIAATINEKRREKSSFCSFCSRLRRGTLYSKALEEGYNKVAIAHHLDDAVESFFMNFTYNGSLRSMPPIY
RAENGLLVIRPLIKVREASSIHFVTSQNIPVAPDCNCPAKQPTSDKPPIARLATKNFLKEMQNLHPRFFDSLENAFNNVQ
ANSFSDAKYLDA

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=253, Percent_Identity=33.596837944664, Blast_Score=150, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI193211090, Length=246, Percent_Identity=35.3658536585366, Blast_Score=122, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 28569; Mature: 28438

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYEISKKVLHIVGKTNATYKLIEEGDKILLGLSGGKDSIMLACILARMQKHAPFKFDFK
CCCHHHHHHHHHHCCCCCEEHEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEE
AVTVHYGLGEDLKWLSDLCQEQGIEHEIIYTQIAATINEKRREKSSFCSFCSRLRRGTLY
EEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
SKALEEGYNKVAIAHHLDDAVESFFMNFTYNGSLRSMPPIYRAENGLLVIRPLIKVREAS
HHHHHCCCCEEEHHHHHHHHHHHHHHHCEECCCCCCCCCCEECCCCEEEEEHHHHHHCCC
SIHFVTSQNIPVAPDCNCPAKQPTSDKPPIARLATKNFLKEMQNLHPRFFDSLENAFNNV
CEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
QANSFSDAKYLDA
CCCCCCCCCCCCC
>Mature Secondary Structure 
AYEISKKVLHIVGKTNATYKLIEEGDKILLGLSGGKDSIMLACILARMQKHAPFKFDFK
CCHHHHHHHHHHCCCCCEEHEEECCCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEE
AVTVHYGLGEDLKWLSDLCQEQGIEHEIIYTQIAATINEKRREKSSFCSFCSRLRRGTLY
EEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
SKALEEGYNKVAIAHHLDDAVESFFMNFTYNGSLRSMPPIYRAENGLLVIRPLIKVREAS
HHHHHCCCCEEEHHHHHHHHHHHHHHHCEECCCCCCCCCCEECCCCEEEEEHHHHHHCCC
SIHFVTSQNIPVAPDCNCPAKQPTSDKPPIARLATKNFLKEMQNLHPRFFDSLENAFNNV
CEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
QANSFSDAKYLDA
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA