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The map label for this gene is aroA [H]

Identifier: 108563416

GI number: 108563416

Start: 1044287

End: 1045576

Strand: Direct

Name: aroA [H]

Synonym: HPAG1_0991

Alternate gene names: 108563416

Gene position: 1044287-1045576 (Clockwise)

Preceding gene: 108563415

Following gene: 108563417

Centisome position: 65.42

GC content: 39.53

Gene sequence:

>1290_bases
GTGATAGAGCTTGACATTAACGCTAGCGATAAATCGCTCTCGCACAGAGCCGTTATTTTTAGCCTACTCGCTCAAAAGCC
TTGTTTCGTGCGGAATTTTTTAATGGGAGAAGATTGTTTAAGCTCTTTGGAAATCGCTCAAAATTTAGGGGCTAAAGTGG
AAAATACCGCCAAAAATTCTTTTAAAATCACGCCTCCAACGGCTATAAAAGAGCCCAGTAAGATTTTAAATTGCAACAAT
TCTGGCACTAGCATGCGTTTATACAGCGGGCTTTTAAGCGCTCAAAAAGGCCTTTTTGTTTTAAGCGGGGACAATTCCTT
AAACGCGCGCCCCATGAAAAGAATCATTGAGCCTTTGAAAGCTTTTGGGGCAAGGATTTTAGGGAGAGAGGATAACCATT
TCGCCCCCTTAGTGATTGTAGGGAGTCCTTTAAAAGCTTGTAATTATGAAAGCCCTATCGCTTCAGCTCAAGTCAAAAGC
GCTTTTGTTTTAAGCGCCTTACAAGCTCAAGGCGTAAGCGTTTATAAAGAAAATGAGCTTAGCCGTAACCACACAGAAAT
CATGCTTAAAAGTTTGGGAGCTAAGATTCACAATCAAGACGGCGTTTTAATGATTTCACCCCTAGAAAAACCCCTAGAAG
CTTTTGATTTTACGATAGCTAATGATCCGTCTAGCGCGTTTTTTTTCGCCCTCGCTTGCGCGATTACGCCAAAAAGCCGC
CTTCTTTTAAAAAATGTCTTGCTCAACCCCACCCGCATAGAAGCTTTTGAAGCGTTGAAAAAAATGGGCGCTTCCATAGA
GTATGTCATTCAATCCAAAGATTTAGAAATGATTGGCGATATTTATGTAGAGCATGCCCCTTTAAAAGCGATCAGCATTG
AGCAAAATATCGCCAGTCTTATTGATGAAATCCCTGCTTTAAGTATCGCTATGCTTTTTGCAAAAGGCAAAAGCATGGTC
AAAAACGCTAAAGATTTACGGGTTAAAGAAAGCGATAGGATAAAAGCCGTTATTTCTAATTTCAAGGCTTTAGGGATTGA
GTGCGAAGAGTTTGAAGACGGGTTTTATATAGAGGGATTAGAAGATATAAGCCCATTAAAACAGCGCTTTTCTCAAAAAA
AACCCCCCCTTATCAAAAGCTTTAATGATCACAGGATTGCGATGAGTTTCGCTATTTTAACTTTAGCGTTGCCTTTAGAA
ATTGATAATTTAGAATGCGCAAACATTTCTTTCCCGCAATTCAAACGCTTACTCAATCTATTCAAAAAAGGGAGTTTTAA
TGGAAATTAA

Upstream 100 bases:

>100_bases
TTTAGAAAAAACCCTGAATGATGAAGAGGTCAATTCAGCCGTGCAAAAAGCGCTTGAAATTTTAGAAAAAGAATTTAACG
CCCGCCTTAAAGGATGATAT

Downstream 100 bases:

>100_bases
AATGGCTAAGGACTATGGTTTTTGTTTTGGCGTCAAAAGAGCGATACAAATCGCTGAAAAAAATCAAAACAGCTTGATTT
TTGGCTCGCTCATTCATAAC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 429; Mature: 429

Protein sequence:

>429_residues
MIELDINASDKSLSHRAVIFSLLAQKPCFVRNFLMGEDCLSSLEIAQNLGAKVENTAKNSFKITPPTAIKEPSKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGARILGREDNHFAPLVIVGSPLKACNYESPIASAQVKS
AFVLSALQAQGVSVYKENELSRNHTEIMLKSLGAKIHNQDGVLMISPLEKPLEAFDFTIANDPSSAFFFALACAITPKSR
LLLKNVLLNPTRIEAFEALKKMGASIEYVIQSKDLEMIGDIYVEHAPLKAISIEQNIASLIDEIPALSIAMLFAKGKSMV
KNAKDLRVKESDRIKAVISNFKALGIECEEFEDGFYIEGLEDISPLKQRFSQKKPPLIKSFNDHRIAMSFAILTLALPLE
IDNLECANISFPQFKRLLNLFKKGSFNGN

Sequences:

>Translated_429_residues
MIELDINASDKSLSHRAVIFSLLAQKPCFVRNFLMGEDCLSSLEIAQNLGAKVENTAKNSFKITPPTAIKEPSKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGARILGREDNHFAPLVIVGSPLKACNYESPIASAQVKS
AFVLSALQAQGVSVYKENELSRNHTEIMLKSLGAKIHNQDGVLMISPLEKPLEAFDFTIANDPSSAFFFALACAITPKSR
LLLKNVLLNPTRIEAFEALKKMGASIEYVIQSKDLEMIGDIYVEHAPLKAISIEQNIASLIDEIPALSIAMLFAKGKSMV
KNAKDLRVKESDRIKAVISNFKALGIECEEFEDGFYIEGLEDISPLKQRFSQKKPPLIKSFNDHRIAMSFAILTLALPLE
IDNLECANISFPQFKRLLNLFKKGSFNGN
>Mature_429_residues
MIELDINASDKSLSHRAVIFSLLAQKPCFVRNFLMGEDCLSSLEIAQNLGAKVENTAKNSFKITPPTAIKEPSKILNCNN
SGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLKAFGARILGREDNHFAPLVIVGSPLKACNYESPIASAQVKS
AFVLSALQAQGVSVYKENELSRNHTEIMLKSLGAKIHNQDGVLMISPLEKPLEAFDFTIANDPSSAFFFALACAITPKSR
LLLKNVLLNPTRIEAFEALKKMGASIEYVIQSKDLEMIGDIYVEHAPLKAISIEQNIASLIDEIPALSIAMLFAKGKSMV
KNAKDLRVKESDRIKAVISNFKALGIECEEFEDGFYIEGLEDISPLKQRFSQKKPPLIKSFNDHRIAMSFAILTLALPLE
IDNLECANISFPQFKRLLNLFKKGSFNGN

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=346, Percent_Identity=26.878612716763, Blast_Score=112, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6320332, Length=451, Percent_Identity=22.6164079822616, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 47299; Mature: 47299

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELDINASDKSLSHRAVIFSLLAQKPCFVRNFLMGEDCLSSLEIAQNLGAKVENTAKNS
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FKITPPTAIKEPSKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLK
EEECCCHHHCCCHHHEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AFGARILGREDNHFAPLVIVGSPLKACNYESPIASAQVKSAFVLSALQAQGVSVYKENEL
HHHHHHCCCCCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCC
SRNHTEIMLKSLGAKIHNQDGVLMISPLEKPLEAFDFTIANDPSSAFFFALACAITPKSR
CCHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHCEEEECCCCHHHHHHHHHHCCCHHH
LLLKNVLLNPTRIEAFEALKKMGASIEYVIQSKDLEMIGDIYVEHAPLKAISIEQNIASL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHHH
IDEIPALSIAMLFAKGKSMVKNAKDLRVKESDRIKAVISNFKALGIECEEFEDGFYIEGL
HHHCCHHHHHHHHHHCHHHHCCHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCCCEEECCH
EDISPLKQRFSQKKPPLIKSFNDHRIAMSFAILTLALPLEIDNLECANISFPQFKRLLNL
HHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHH
FKKGSFNGN
HHCCCCCCC
>Mature Secondary Structure
MIELDINASDKSLSHRAVIFSLLAQKPCFVRNFLMGEDCLSSLEIAQNLGAKVENTAKNS
CEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
FKITPPTAIKEPSKILNCNNSGTSMRLYSGLLSAQKGLFVLSGDNSLNARPMKRIIEPLK
EEECCCHHHCCCHHHEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHH
AFGARILGREDNHFAPLVIVGSPLKACNYESPIASAQVKSAFVLSALQAQGVSVYKENEL
HHHHHHCCCCCCCCCCEEEECCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCCC
SRNHTEIMLKSLGAKIHNQDGVLMISPLEKPLEAFDFTIANDPSSAFFFALACAITPKSR
CCHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHCEEEECCCCHHHHHHHHHHCCCHHH
LLLKNVLLNPTRIEAFEALKKMGASIEYVIQSKDLEMIGDIYVEHAPLKAISIEQNIASL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHCCCCCEEEEHHHHHHHH
IDEIPALSIAMLFAKGKSMVKNAKDLRVKESDRIKAVISNFKALGIECEEFEDGFYIEGL
HHHCCHHHHHHHHHHCHHHHCCHHHCCCCCHHHHHHHHHHHHHCCCCHHHCCCCEEECCH
EDISPLKQRFSQKKPPLIKSFNDHRIAMSFAILTLALPLEIDNLECANISFPQFKRLLNL
HHHHHHHHHHHCCCCCHHHCCCCCHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHH
FKKGSFNGN
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA