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The map label for this gene is cysS [H]

Identifier: 108563291

GI number: 108563291

Start: 902488

End: 903885

Strand: Direct

Name: cysS [H]

Synonym: HPAG1_0866

Alternate gene names: 108563291

Gene position: 902488-903885 (Clockwise)

Preceding gene: 108563290

Following gene: 108563292

Centisome position: 56.53

GC content: 38.84

Gene sequence:

>1398_bases
ATGTTTATTTATGATACCAAATCAAAACAAAAAGTCCCTTTTGAGCCTTTAGTTAAAAATAAGGCGAATATTTATGTGTG
CGGGCCTACGGTGTATGATGACGCTCATTTAGGGCATGCCAGGAGCGCGATTGCTTTTGATTTGTTAAGGCGCACGCTTG
AATTGAGCGGCTATGAAGTGATGTTAGTAAGGAATTTCACGGATATTGACGATAAAATCATCAACAAAGCCCTAAAAGAA
AACAAAAGCATTCAAGAATTAAGCAGCATTTATATTGAATCTTACACGAGGGATTTGAACGCTTTGAACGTGAAAAAACC
CAGCCTAGAGCCTAAAGCGAGCGAGTATTTAGACGCTATGGTGCACATGATTGAAACGCTTTTAGAAAAAAATATCGCTT
ATAGAGTCTCTAATGGGGATATTTATTTAGACACGAGCAAGGATAAAGATTACGGCTCTTTGAGCGTGCATAATAGTAGC
ATTGAATTTGGCCGTATTGGTTTGGTGCAAGAAAAACGGCTTGAGCAGGATTTTGTGTTATGGAAAAGCTATAAGGGGGA
TAATGATGTGGGCTTTGATAGCCCTTTAGGCAAAGGACGCCCTGGCTGGCATATAGAATGCTCTAGCATGGTTTTTGAAA
CTTTAGCGCTCGCTAACACCCCTTATCAAATTGATATTCATGCAGGCGGATCGGATTTGTTATTCCCCCACCATGAAAAT
GAAGCGTGCCAAACCCGTTGCGCCTTTGGCGTGGAGCTTGCCAAATACTGGATGCATAATGGCTTTGTGAATATCAATAA
TGAAAAAATGTCTAAAAGTTTAGGGAATAGCTTTTTTGTTAAAGACGCTCTCAAAAACTATGATGGCGAAATTTTGCGCA
ATTACTTGCTAGGGGTGCATTATCGCTCTGTTTTGAATTTCAATGAAGAAGACTTGTTGGTGAGTAAAAAACGCTTGGAT
AAAATCTATCGCCTAAAACAGCGCGTTTTAGGGACTTTAGGCGGAATAAATCCAAACTTTAAAAAAGAAATTTTAGAATG
CATGCAAGATGATTTAAACGTTTCTAAAGCGTTGAGCGTTTTAGAAAACATGCTTTCTTCCACTAATGAAAAATTAGATC
AAAACCCTAAAAACAAGGCTTTAAAGGGCGAAATTTTAGCGAATTTGAAATTTGTAGAAGAACTGCTTGGCATCGGGTTT
AAAGACCCTAGCGCCTATTTCCAATTAGGCGTGAGCGAGAGCGAAAAACAAGAAATTGAAAACAAGATAGAAGAAAGAAA
ACGCGCCAAAGAGCAAAAAGATTTTTTAAAAGCCGATCGCATCAGAGAAGAGCTTTTAAACCGCAAAATCGCTTTGATGG
ACACCCCACAAGGCACGATTTGGGAGAAGTTTTTTTAA

Upstream 100 bases:

>100_bases
TGTAATCTTTTTTCTCGCTTGCGTGGAAATCTTATTACTCTTAGCGTTCAAATCGTGGGTTACACATTTATATTTATTTT
ATTATTTTCAAGGTTTTTAA

Downstream 100 bases:

>100_bases
GCTTTTCAGATTTTACCTATTTACACATTCTAGCCCAAAATTTCAGCATTTTTGCTTTTTAATCTTGTTAAGTTTTATTT
TCATTTACTTTAATTTGATA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MFIYDTKSKQKVPFEPLVKNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVMLVRNFTDIDDKIINKALKE
NKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVHMIETLLEKNIAYRVSNGDIYLDTSKDKDYGSLSVHNSS
IEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANTPYQIDIHAGGSDLLFPHHEN
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLVSKKRLD
KIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSVLENMLSSTNEKLDQNPKNKALKGEILANLKFVEELLGIGF
KDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADRIREELLNRKIALMDTPQGTIWEKFF

Sequences:

>Translated_465_residues
MFIYDTKSKQKVPFEPLVKNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVMLVRNFTDIDDKIINKALKE
NKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVHMIETLLEKNIAYRVSNGDIYLDTSKDKDYGSLSVHNSS
IEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANTPYQIDIHAGGSDLLFPHHEN
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLVSKKRLD
KIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSVLENMLSSTNEKLDQNPKNKALKGEILANLKFVEELLGIGF
KDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADRIREELLNRKIALMDTPQGTIWEKFF
>Mature_465_residues
MFIYDTKSKQKVPFEPLVKNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEVMLVRNFTDIDDKIINKALKE
NKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAMVHMIETLLEKNIAYRVSNGDIYLDTSKDKDYGSLSVHNSS
IEFGRIGLVQEKRLEQDFVLWKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANTPYQIDIHAGGSDLLFPHHEN
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVHYRSVLNFNEEDLLVSKKRLD
KIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSVLENMLSSTNEKLDQNPKNKALKGEILANLKFVEELLGIGF
KDPSAYFQLGVSESEKQEIENKIEERKRAKEQKDFLKADRIREELLNRKIALMDTPQGTIWEKFF

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=484, Percent_Identity=30.9917355371901, Blast_Score=217, Evalue=2e-56,
Organism=Homo sapiens, GI303304987, Length=386, Percent_Identity=29.5336787564767, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI21269877, Length=386, Percent_Identity=29.5336787564767, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI62240992, Length=386, Percent_Identity=29.5336787564767, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI10835051, Length=386, Percent_Identity=29.5336787564767, Blast_Score=146, Evalue=4e-35,
Organism=Escherichia coli, GI1786737, Length=468, Percent_Identity=39.957264957265, Blast_Score=337, Evalue=1e-93,
Organism=Caenorhabditis elegans, GI17509795, Length=258, Percent_Identity=30.6201550387597, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17509797, Length=258, Percent_Identity=30.6201550387597, Blast_Score=120, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324082, Length=448, Percent_Identity=28.7946428571429, Blast_Score=151, Evalue=2e-37,
Organism=Drosophila melanogaster, GI19922218, Length=508, Percent_Identity=29.5275590551181, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI19922364, Length=259, Percent_Identity=32.8185328185328, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53268; Mature: 53268

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFIYDTKSKQKVPFEPLVKNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEV
CEEECCCCCCCCCCCHHHCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEE
MLVRNFTDIDDKIINKALKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAM
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
VHMIETLLEKNIAYRVSNGDIYLDTSKDKDYGSLSVHNSSIEFGRIGLVQEKRLEQDFVL
HHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
WKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANTPYQIDIHAGGSDLLFPHHEN
HHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVH
HHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHH
YRSVLNFNEEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
LENMLSSTNEKLDQNPKNKALKGEILANLKFVEELLGIGFKDPSAYFQLGVSESEKQEIE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCHHHHHHH
NKIEERKRAKEQKDFLKADRIREELLNRKIALMDTPQGTIWEKFF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCC
>Mature Secondary Structure
MFIYDTKSKQKVPFEPLVKNKANIYVCGPTVYDDAHLGHARSAIAFDLLRRTLELSGYEV
CEEECCCCCCCCCCCHHHCCCCEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHCCCEEE
MLVRNFTDIDDKIINKALKENKSIQELSSIYIESYTRDLNALNVKKPSLEPKASEYLDAM
EEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
VHMIETLLEKNIAYRVSNGDIYLDTSKDKDYGSLSVHNSSIEFGRIGLVQEKRLEQDFVL
HHHHHHHHHCCCEEEEECCCEEEECCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHH
WKSYKGDNDVGFDSPLGKGRPGWHIECSSMVFETLALANTPYQIDIHAGGSDLLFPHHEN
HHCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
EACQTRCAFGVELAKYWMHNGFVNINNEKMSKSLGNSFFVKDALKNYDGEILRNYLLGVH
HHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHH
YRSVLNFNEEDLLVSKKRLDKIYRLKQRVLGTLGGINPNFKKEILECMQDDLNVSKALSV
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHH
LENMLSSTNEKLDQNPKNKALKGEILANLKFVEELLGIGFKDPSAYFQLGVSESEKQEIE
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCCCHHHHHHH
NKIEERKRAKEQKDFLKADRIREELLNRKIALMDTPQGTIWEKFF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA