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The map label for this gene is mraY [H]

Identifier: 108562894

GI number: 108562894

Start: 485246

End: 486307

Strand: Direct

Name: mraY [H]

Synonym: HPAG1_0469

Alternate gene names: 108562894

Gene position: 485246-486307 (Clockwise)

Preceding gene: 108562890

Following gene: 108562895

Centisome position: 30.4

GC content: 41.34

Gene sequence:

>1062_bases
ATGCTCTATTCTTTACTATATGGCTATTTCAATATCAATCTTTTCCAGTATTTGACCTTTAGAGCAGGGTTAGGGTTTTT
CATAGCCTTTTTCCTCACGCTTTTTTTAATGCCTAAATTCATTCTATGGGCCAAGGCTAAAAAGGCTAACCAGCCCATTT
CAAGCTTTGTGCCAAGCCACCAGAATAAAAAGGATACCCCTACGATGGGAGGGATTGTGTTTGTTTTTGCAACCATTGTT
GCGAGCGTGTTGTGCGCGTCTTTGGGTAATCTTTATGTGTTGTTAGGGATAATCGTGTTAGTGGGCTTTAGTTTTGTGGG
TTTTAGAGACGATTACACTAAAATCAACCAACAAAATAACGCCGGGATGAGCGCGAAAATGAAATTTGGCATGCTGTTTG
TCCTTTCGCTTGTGGTGTCCGTTTTATTAAGCCTTAAAGGGTTAGACACTTTTTTATACGCGCCTTTTTTGAAAAACCCC
TTGTTTGAAATGCCCACGATGTTAGCGGTTGGTTTTTGGGTGTTGGTTTTTTTATCCACGAGCAATGCGGTGAATTTAAC
CGACGGGTTAGACGGCTTAGCGAGCGTGCCTAGCATTTTCACCCTTTTAAGCCTTTCTATCTTTGTGTATGTGGCAGGGA
ATGCGGAATTTTCTAAATACTTGCTCTATCCTAAAGTCATAGATGTGGGGGAATTGTTTGTTGTCTCGCTGGCTTTAGTG
GGATCGCTCTTTGGCTTTTTGTGGTATAACTGCAACCCGGCAAGCGTGTTTATGGGCGATAGCGGGAGTTTGGCTTTGGG
GGGGTTTATCGCTTATAACGCTATTGTTTCGCATAATGAAATCTTACTCGTTTTAATGGGATCTATTTTTGTGGTAGAAA
CTTTGTCTGTGATCTTGCAAGTAGGGAGTTATAAAACCCGCAAAAAACGCCTTTTTTTAATGGCGCCTATCCATCATCAT
TTTGAGCAAAAGGGTTGGGCAGAAAACAAAGTGATCGTGCGTTTTTGGATCATTTCTATGCTGAGTAATTTAGTCGCTCT
TTTAAGCTTGAAGGTGCGTTAA

Upstream 100 bases:

>100_bases
ACTTCTGTTCTACCCTATTCATGCTATTTTTAAGTAAATCAATTTGCGCTACAATTTTCTTTTTTTCTAAATTTCAAGCA
TGGCGATTTTAGGGGATTTT

Downstream 100 bases:

>100_bases
AATGAAAATCTCTTTATTGGGGCATGGCAAAACCACTCTAGCCCTAGCGCGTTTTTTTAAAAAAAACCATAACGAAGTCA
AATTTTTTGATGATCAATTC

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSHQNKKDTPTMGGIVFVFATIV
ASVLCASLGNLYVLLGIIVLVGFSFVGFRDDYTKINQQNNAGMSAKMKFGMLFVLSLVVSVLLSLKGLDTFLYAPFLKNP
LFEMPTMLAVGFWVLVFLSTSNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALV
GSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVVETLSVILQVGSYKTRKKRLFLMAPIHHH
FEQKGWAENKVIVRFWIISMLSNLVALLSLKVR

Sequences:

>Translated_353_residues
MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSHQNKKDTPTMGGIVFVFATIV
ASVLCASLGNLYVLLGIIVLVGFSFVGFRDDYTKINQQNNAGMSAKMKFGMLFVLSLVVSVLLSLKGLDTFLYAPFLKNP
LFEMPTMLAVGFWVLVFLSTSNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALV
GSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVVETLSVILQVGSYKTRKKRLFLMAPIHHH
FEQKGWAENKVIVRFWIISMLSNLVALLSLKVR
>Mature_353_residues
MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSHQNKKDTPTMGGIVFVFATIV
ASVLCASLGNLYVLLGIIVLVGFSFVGFRDDYTKINQQNNAGMSAKMKFGMLFVLSLVVSVLLSLKGLDTFLYAPFLKNP
LFEMPTMLAVGFWVLVFLSTSNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALV
GSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVVETLSVILQVGSYKTRKKRLFLMAPIHHH
FEQKGWAENKVIVRFWIISMLSNLVALLSLKVR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=353, Percent_Identity=45.3257790368272, Blast_Score=277, Evalue=6e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 39155; Mature: 39155

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
QNKKDTPTMGGIVFVFATIVASVLCASLGNLYVLLGIIVLVGFSFVGFRDDYTKINQQNN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
AGMSAKMKFGMLFVLSLVVSVLLSLKGLDTFLYAPFLKNPLFEMPTMLAVGFWVLVFLST
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
SNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALV
CCCEECCCCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCHHHHHHHHHHHHHHHHH
GSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVVETLSVILQ
HHHHHHHHCCCCCCEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGSYKTRKKRLFLMAPIHHHFEQKGWAENKVIVRFWIISMLSNLVALLSLKVR
HCCCCHHHHEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLYSLLYGYFNINLFQYLTFRAGLGFFIAFFLTLFLMPKFILWAKAKKANQPISSFVPSH
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC
QNKKDTPTMGGIVFVFATIVASVLCASLGNLYVLLGIIVLVGFSFVGFRDDYTKINQQNN
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCC
AGMSAKMKFGMLFVLSLVVSVLLSLKGLDTFLYAPFLKNPLFEMPTMLAVGFWVLVFLST
CCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHC
SNAVNLTDGLDGLASVPSIFTLLSLSIFVYVAGNAEFSKYLLYPKVIDVGELFVVSLALV
CCCEECCCCCCHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHCHHHHHHHHHHHHHHHHH
GSLFGFLWYNCNPASVFMGDSGSLALGGFIAYNAIVSHNEILLVLMGSIFVVETLSVILQ
HHHHHHHHCCCCCCEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VGSYKTRKKRLFLMAPIHHHFEQKGWAENKVIVRFWIISMLSNLVALLSLKVR
HCCCCHHHHEEEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA