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The map label for this gene is minD [H]

Identifier: 108562760

GI number: 108562760

Start: 345961

End: 346767

Strand: Direct

Name: minD [H]

Synonym: HPAG1_0335

Alternate gene names: 108562760

Gene position: 345961-346767 (Clockwise)

Preceding gene: 108562759

Following gene: 108562761

Centisome position: 21.67

GC content: 41.88

Gene sequence:

>807_bases
ATGGCAATAGTAGTTACTATCACTTCAGGCAAGGGGGGCGTGGGTAAAAGCACCACCACGGCTAATTTAGCGATCGGCTT
GGCTGAGAGCGGTAAAAAAGTCGTAGCGGTTGATTTTGACATAGGCCTTAGGAACTTGGACATGATTTTAGGCTTAGAAA
ATCGCATTGTTTATGATGTGGTGGATGTGATGGAAAAAAATTGCAACCTTTCGCAGGCTTTGATCACGGATAAAAAGACG
AAAAACCTTTCTTTTTTAGCGGCCTCACAAAGTAAGGATAAAAATATTTTAGATAAGGAAAAAGTAGCGATTTTAATCAA
CGCTTTAAGGGCGGATTTTGACTATATTTTGATTGACTCACCAGCTGGGATTGAAAGCGGTTTTGAGCATGCGATTTTGC
ATGCGGACATGGCGTTAGTGGTGGTAACGCCGGAGGTAAGCTCTTTAAGAGATAGCGACAGAGTGGTTGGCATTATTGAT
GCGAAGTCTAATCGGGCCAAAAAGGGCATGGAGGTGCATAAGCATTTGATAATCAATCGCTTAAAACCTGAATTAGTGGC
AAATGGCGAGATGATTCCTATAGAAGAAGTGCTTAAGATTTTATGCTTGCCTTTAATTGGGATCATTCCTGAAGATCACC
ATATTATTTCAGCGACCAATAAGGGCGAGCCGGTGATTCGCGCAGATTGCGAGAGCGCAAAGGCTTACCAACGCATCACC
AGAAGGATTTTAGGCGAAGAAGTGGAATATGTGGAATTTAAGGCTAAAAGAGGTTTTTTTAGCACGTTAAAAGGGATATT
TTCATGA

Upstream 100 bases:

>100_bases
AGAGGAAAGCCCTTAAAGAGACTAAAATAGAACAAATTGGGGAAATTTTACGCGCCCCATTCAACCATAAAAAATAAATC
ATTAAATTAAAAGGAATCAT

Downstream 100 bases:

>100_bases
GTTTGTTTGGTTTTTTTAAAAACAAAGGGAGCGCGACCACCGCAACAGATAGATTGAAATTGATTTTAGCCAAAGAGCGC
ACTTTAAATTTACCCTACAT

Product: cell division inhibitor

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MAIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKT
KNLSFLAASQSKDKNILDKEKVAILINALRADFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVVGIID
AKSNRAKKGMEVHKHLIINRLKPELVANGEMIPIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRADCESAKAYQRIT
RRILGEEVEYVEFKAKRGFFSTLKGIFS

Sequences:

>Translated_268_residues
MAIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKT
KNLSFLAASQSKDKNILDKEKVAILINALRADFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVVGIID
AKSNRAKKGMEVHKHLIINRLKPELVANGEMIPIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRADCESAKAYQRIT
RRILGEEVEYVEFKAKRGFFSTLKGIFS
>Mature_267_residues
AIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDVVDVMEKNCNLSQALITDKKTK
NLSFLAASQSKDKNILDKEKVAILINALRADFDYILIDSPAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVVGIIDA
KSNRAKKGMEVHKHLIINRLKPELVANGEMIPIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRADCESAKAYQRITR
RILGEEVEYVEFKAKRGFFSTLKGIFS

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Homo sapiens, GI118572611, Length=265, Percent_Identity=26.7924528301887, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=49.6296296296296, Blast_Score=265, Evalue=2e-72,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 29305; Mature: 29173

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDV
CEEEEEEECCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEEECCCHHHHHH
VDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNILDKEKVAILINALRADFDYILIDS
HHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVVGIIDAKSNRAKKGMEVHKHLIINR
CCCCCCCHHHHHEECCEEEEEECCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LKPELVANGEMIPIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRADCESAKAYQRIT
CCHHHCCCCCEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHH
RRILGEEVEYVEFKAKRGFFSTLKGIFS
HHHHCCCHHEEEEHHCCCHHHHHHHHCC
>Mature Secondary Structure 
AIVVTITSGKGGVGKSTTTANLAIGLAESGKKVVAVDFDIGLRNLDMILGLENRIVYDV
EEEEEEECCCCCCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEEECCCHHHHHH
VDVMEKNCNLSQALITDKKTKNLSFLAASQSKDKNILDKEKVAILINALRADFDYILIDS
HHHHHCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEC
PAGIESGFEHAILHADMALVVVTPEVSSLRDSDRVVGIIDAKSNRAKKGMEVHKHLIINR
CCCCCCCHHHHHEECCEEEEEECCCHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHH
LKPELVANGEMIPIEEVLKILCLPLIGIIPEDHHIISATNKGEPVIRADCESAKAYQRIT
CCHHHCCCCCEECHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHH
RRILGEEVEYVEFKAKRGFFSTLKGIFS
HHHHCCCHHEEEEHHCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]