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The map label for this gene is rfaC [H]

Identifier: 108562706

GI number: 108562706

Start: 284247

End: 285269

Strand: Direct

Name: rfaC [H]

Synonym: HPAG1_0281

Alternate gene names: 108562706

Gene position: 284247-285269 (Clockwise)

Preceding gene: 108562705

Following gene: 108562707

Centisome position: 17.81

GC content: 37.15

Gene sequence:

>1023_bases
TTGAAAATAGCGATTGTCAGGCTTTCAGCGCTTGGGGATATTATTGTGAGCGCGGTGTTTTTAGCGGCTATCAAAGAGCG
TTTTACTGACGCTCAAATAGAATGGTTCGTGGATGAGAGATTCAGCGCGATTTTAGAGCATTCCCCTTATATTGATAAAT
TACACCCCATCGCTTTAAAAAGCGCGCTTAAAACCTTTAACCCTTTGAAGATTTTCAAGCTTTTTAAATCTTTAAGGGCT
TATGAATACGATATAGTCATTGACATGCAAGGCCTAGTCAAATCCGCTCTCATCACTCAAACGTTAAAAGCCCCTAAAAA
AGTCGGCTTTGATTACGCTTCGGCTAGAGAGGGTTTGAGTGCGTTTTTTTACTCGCAAAAAGTTTCTATCGCTTATGATG
AGCCCATTTTAAAACGCAATTTCACGCTCCTATTCCATGCCCTAAACTTACCCCAAAAAGAAATTTTAAAAGAAATTTCA
GAGAGCTTAAGCTCTAGATCTAAAGTGTTTTCTTACCAACCTTCTCCAAAAATTGATGCGTTAAATTTGAATAAGAATAA
GCTAAAAATCCTTTTTGTTTTAGAAACTTCTAAAATCAATAAAACTTACCCCATAGAGCGTTTTAAAGAGCTGGCTTTGA
TGCTAGAAAATTTTCAAATTTGCTTGTTATGGCATGCTGATGAAGATAAGGCCACTACGCTTTATCATTCTTTAAAAAAC
CAATGCGATGTGTTATTGCTCCCTAAACTCACTTTAAACGAGGTTAAGGCGTTGCTTTTTAAAATGGATTTGATTATTGG
GGGCGATACGGGCATTACGCATTTAGCATGGGCGTTGCAAAAACCCAGTATCACCCTTTATGGCAACACGCCCATGGAGC
GTTTTAAATTAGAAAGCCCGATCAATGTTTCGCTCACCGGTAATTCAAACGCCAGCTACCATAAAAAGGATTTTTCTATC
CAAAATATAGAGCCTAAAAAAATTAAAGAATGCGTTTTAAACATTTTAAAGGAAAAAGAATGA

Upstream 100 bases:

>100_bases
AAAAAAACAAGCTTGTGATCCATTCTAGCGATACGCTTTACTTGGCTAAAGAGATGCTCCCTAAACTCGTTAAGCCCATT
GCTTTGATGATAGAGTTTGC

Downstream 100 bases:

>100_bases
CTTATAAAGAACGACTCATACACGAAAAGATATTGAACCAAAACGACAAGGGTTTGAAAACGGAATTACGCATTTTGAGT
ATTTTTATCGTGGAATCTTT

Product: lipopolysaccharide heptosyltransferase-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKIAIVRLSALGDIIVSAVFLAAIKERFTDAQIEWFVDERFSAILEHSPYIDKLHPIALKSALKTFNPLKIFKLFKSLRA
YEYDIVIDMQGLVKSALITQTLKAPKKVGFDYASAREGLSAFFYSQKVSIAYDEPILKRNFTLLFHALNLPQKEILKEIS
ESLSSRSKVFSYQPSPKIDALNLNKNKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKATTLYHSLKN
QCDVLLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVSLTGNSNASYHKKDFSI
QNIEPKKIKECVLNILKEKE

Sequences:

>Translated_340_residues
MKIAIVRLSALGDIIVSAVFLAAIKERFTDAQIEWFVDERFSAILEHSPYIDKLHPIALKSALKTFNPLKIFKLFKSLRA
YEYDIVIDMQGLVKSALITQTLKAPKKVGFDYASAREGLSAFFYSQKVSIAYDEPILKRNFTLLFHALNLPQKEILKEIS
ESLSSRSKVFSYQPSPKIDALNLNKNKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKATTLYHSLKN
QCDVLLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVSLTGNSNASYHKKDFSI
QNIEPKKIKECVLNILKEKE
>Mature_340_residues
MKIAIVRLSALGDIIVSAVFLAAIKERFTDAQIEWFVDERFSAILEHSPYIDKLHPIALKSALKTFNPLKIFKLFKSLRA
YEYDIVIDMQGLVKSALITQTLKAPKKVGFDYASAREGLSAFFYSQKVSIAYDEPILKRNFTLLFHALNLPQKEILKEIS
ESLSSRSKVFSYQPSPKIDALNLNKNKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKATTLYHSLKN
QCDVLLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESPINVSLTGNSNASYHKKDFSI
QNIEPKKIKECVLNILKEKE

Specific function: Heptose transfer to the lipopolysaccharide core. It transfers the innnermost heptose to [4'-P](3-deoxy-D-manno- octulosonic acid)2-IVA [H]

COG id: COG0859

COG function: function code M; ADP-heptose:LPS heptosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 9 family [H]

Homologues:

Organism=Escherichia coli, GI1790051, Length=301, Percent_Identity=29.5681063122924, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1790062, Length=286, Percent_Identity=24.1258741258741, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002201
- InterPro:   IPR011908 [H]

Pfam domain/function: PF01075 Glyco_transf_9 [H]

EC number: 2.4.1.-

Molecular weight: Translated: 38802; Mature: 38802

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIVRLSALGDIIVSAVFLAAIKERFTDAQIEWFVDERFSAILEHSPYIDKLHPIALK
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHH
SALKTFNPLKIFKLFKSLRAYEYDIVIDMQGLVKSALITQTLKAPKKVGFDYASAREGLS
HHHHHCCHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AFFYSQKVSIAYDEPILKRNFTLLFHALNLPQKEILKEISESLSSRSKVFSYQPSPKIDA
HHHHHCEEEEEECCCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEE
LNLNKNKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKATTLYHSLKN
EECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHC
QCDVLLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESP
CCCEEEECCCCHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHCCCCC
INVSLTGNSNASYHKKDFSIQNIEPKKIKECVLNILKEKE
CEEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIAIVRLSALGDIIVSAVFLAAIKERFTDAQIEWFVDERFSAILEHSPYIDKLHPIALK
CEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHH
SALKTFNPLKIFKLFKSLRAYEYDIVIDMQGLVKSALITQTLKAPKKVGFDYASAREGLS
HHHHHCCHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
AFFYSQKVSIAYDEPILKRNFTLLFHALNLPQKEILKEISESLSSRSKVFSYQPSPKIDA
HHHHHCEEEEEECCCHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHEEEECCCCCEEE
LNLNKNKLKILFVLETSKINKTYPIERFKELALMLENFQICLLWHADEDKATTLYHSLKN
EECCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHC
QCDVLLLPKLTLNEVKALLFKMDLIIGGDTGITHLAWALQKPSITLYGNTPMERFKLESP
CCCEEEECCCCHHHHHHHHHHHHEEEECCCCHHHHHHHCCCCCEEEEECCCHHHHCCCCC
INVSLTGNSNASYHKKDFSIQNIEPKKIKECVLNILKEKE
CEEEEECCCCCCEECCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1527014; 11677609; 1657881 [H]