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The map label for this gene is queC2

Identifier: 103488120

GI number: 103488120

Start: 2788101

End: 2788811

Strand: Reverse

Name: queC2

Synonym: Sala_2643

Alternate gene names: 103488120

Gene position: 2788811-2788101 (Counterclockwise)

Preceding gene: 103488121

Following gene: 103488119

Centisome position: 83.37

GC content: 62.73

Gene sequence:

>711_bases
ATGACCGGCGACGCTGGCGCGCTCGTCCTTTTCTCTGGTGGGCAGGACAGCGCCACTTGTCTTGCCTGGGCATTGGACCG
GTTCGAGACCGTCGAGACCGTCGGGTTCGACTATGGCCAGCGTCACCGCGTCGAACTCGAATGCCGCGACGATTTTCGTG
CGCGCATTGTTGAATTGAATCCGGCATGGGCCGCGCGGCTCGGGCCGGATCACAAGCTCGACCTCTCGGTGCTGGGCCAG
GTCAGCGAGACCGCGCTCACCCGCGATGCCGAGATCGCGCTGCGCGCCGATGGCTTGCCCAACACCTTCGTGCCCGGTCG
CAATCTGTTGTTCTTTACGCTCGCCGCTGCGCTCGCCTCACGCCGCGAACTGCGGCATCTCGTCGGCGGCATGTGCGAGA
CCGACTATTCGGGCTATCCCGATTGCCGCGACGATACGCTCAAATCGCTCCAAGTCACGCTCAACCTCGGTATTGGCAGC
CGCTCGGTCGTCCACACGCCGTTGATGTGGCTCGATAAGGCGCAGACCTGGGGTCTGGCAAAAATACTGGGTGGCGAGAA
ACTGGTCGACCTCATCCGCACCGGCACTCATACTTGCTATCGTGGCGACCACGATCGCTTGCAGGACTGGGGCTACGGCT
GTGGCACCTGTCCGGCTTGCGAATTGCGCATGAAGGGCTGGCAAGAACATCGGAGCAGTTTGGACGAGTAG

Upstream 100 bases:

>100_bases
GGAACCGGCTCTCGCCCGAACTCGACAATCTGTTCAAGGTCAGCGTCTACCGCGACAGCAGCGGCGACGCCTGCACCTAT
TGGGGCGAGGAAGTCGCGGC

Downstream 100 bases:

>100_bases
CGCTTGCCGTTTTTGGTTGGTTCTCAACCCTCTGTCAGTAAGATGGTCCTAACGGTGCGATTGTGGGGAATCGCCCATCG
AGGGATACGGGTCTGTTCAG

Product: ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase 2; PreQ(0) synthase 2; Queuosine biosynthesis protein queC 2

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTGDAGALVLFSGGQDSATCLAWALDRFETVETVGFDYGQRHRVELECRDDFRARIVELNPAWAARLGPDHKLDLSVLGQ
VSETALTRDAEIALRADGLPNTFVPGRNLLFFTLAAALASRRELRHLVGGMCETDYSGYPDCRDDTLKSLQVTLNLGIGS
RSVVHTPLMWLDKAQTWGLAKILGGEKLVDLIRTGTHTCYRGDHDRLQDWGYGCGTCPACELRMKGWQEHRSSLDE

Sequences:

>Translated_236_residues
MTGDAGALVLFSGGQDSATCLAWALDRFETVETVGFDYGQRHRVELECRDDFRARIVELNPAWAARLGPDHKLDLSVLGQ
VSETALTRDAEIALRADGLPNTFVPGRNLLFFTLAAALASRRELRHLVGGMCETDYSGYPDCRDDTLKSLQVTLNLGIGS
RSVVHTPLMWLDKAQTWGLAKILGGEKLVDLIRTGTHTCYRGDHDRLQDWGYGCGTCPACELRMKGWQEHRSSLDE
>Mature_235_residues
TGDAGALVLFSGGQDSATCLAWALDRFETVETVGFDYGQRHRVELECRDDFRARIVELNPAWAARLGPDHKLDLSVLGQV
SETALTRDAEIALRADGLPNTFVPGRNLLFFTLAAALASRRELRHLVGGMCETDYSGYPDCRDDTLKSLQVTLNLGIGSR
SVVHTPLMWLDKAQTWGLAKILGGEKLVDLIRTGTHTCYRGDHDRLQDWGYGCGTCPACELRMKGWQEHRSSLDE

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=229, Percent_Identity=46.7248908296943, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC2_SPHAL (Q1GPS4)

Other databases:

- EMBL:   CP000356
- RefSeq:   YP_617681.1
- ProteinModelPortal:   Q1GPS4
- SMR:   Q1GPS4
- GeneID:   4081773
- GenomeReviews:   CP000356_GR
- KEGG:   sal:Sala_2643
- NMPDR:   fig|317655.9.peg.2516
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK864419
- BioCyc:   SALA317655:SALA_2643-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 26141; Mature: 26010

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGDAGALVLFSGGQDSATCLAWALDRFETVETVGFDYGQRHRVELECRDDFRARIVELN
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEC
PAWAARLGPDHKLDLSVLGQVSETALTRDAEIALRADGLPNTFVPGRNLLFFTLAAALAS
CHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RRELRHLVGGMCETDYSGYPDCRDDTLKSLQVTLNLGIGSRSVVHTPLMWLDKAQTWGLA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHH
KILGGEKLVDLIRTGTHTCYRGDHDRLQDWGYGCGTCPACELRMKGWQEHRSSLDE
HHHCCHHHHHHHHCCCCCEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGDAGALVLFSGGQDSATCLAWALDRFETVETVGFDYGQRHRVELECRDDFRARIVELN
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEEC
PAWAARLGPDHKLDLSVLGQVSETALTRDAEIALRADGLPNTFVPGRNLLFFTLAAALAS
CHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RRELRHLVGGMCETDYSGYPDCRDDTLKSLQVTLNLGIGSRSVVHTPLMWLDKAQTWGLA
HHHHHHHHCCCCCCCCCCCCCCCHHHHHEEEEEEEECCCCCHHHHHHHHHHHCCCCCCHH
KILGGEKLVDLIRTGTHTCYRGDHDRLQDWGYGCGTCPACELRMKGWQEHRSSLDE
HHHCCHHHHHHHHCCCCCEECCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA