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The map label for this gene is hmrR2 [H]

Identifier: 103488050

GI number: 103488050

Start: 2712672

End: 2713097

Strand: Reverse

Name: hmrR2 [H]

Synonym: Sala_2572

Alternate gene names: 103488050

Gene position: 2713097-2712672 (Counterclockwise)

Preceding gene: 103488052

Following gene: 103488049

Centisome position: 81.1

GC content: 59.39

Gene sequence:

>426_bases
ATGACTGCGGCACTCACGATCGGAGAACTCGGACGGCGAACGGGAACCAAAGTCGAAACTGTCCGATATTACGAGAAGAT
CGGTCTGCTCGCGCTGCCGAAGCGGACCCGAGGCAACTATCGTGCTTATGGCGAGAATGACGTTGCGCGTCTTTCCTTCA
TTCGCCGGACGCGCGATCTGGGCTTTTCTATCGATCAGGTCCGGGCGCTGTTGTCGCTGGCGGGCGATGAATCCCGCGAT
TGTGCAACGATCGACGCAATTGCCTCGACACATCTTGGGGAAATCGATCGTAAGCTTGCCGATCTTGCCGTTCTGCGCCG
AGAGATCGCCGCGCTGGTCGCGTCATGCGAAGGCGGCACGATCGGTCAGTGCCGCATATTGGAGGCGCTTGCTCCGATCG
CAGGAAGGCGGCCGCCCGATATTTGA

Upstream 100 bases:

>100_bases
GGTCGCCGCGCAACAGTCATCGCATCCAGCCATATTGCCTCCTCGATTCTTTCGATTCGGCTTCCCATATGCACCCTGAA
GCAGCTACAAGGTCAAGGGG

Downstream 100 bases:

>100_bases
GCACGGCGGACGAGATACCCCGATCGCCATATTGGAGCTGTGGTCATGAAGGCTCTGATTGCCTTCGATCTTGACGGCAC
ACTTGCCGAAAGCAAGCAAC

Product: MerR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 140

Protein sequence:

>141_residues
MTAALTIGELGRRTGTKVETVRYYEKIGLLALPKRTRGNYRAYGENDVARLSFIRRTRDLGFSIDQVRALLSLAGDESRD
CATIDAIASTHLGEIDRKLADLAVLRREIAALVASCEGGTIGQCRILEALAPIAGRRPPDI

Sequences:

>Translated_141_residues
MTAALTIGELGRRTGTKVETVRYYEKIGLLALPKRTRGNYRAYGENDVARLSFIRRTRDLGFSIDQVRALLSLAGDESRD
CATIDAIASTHLGEIDRKLADLAVLRREIAALVASCEGGTIGQCRILEALAPIAGRRPPDI
>Mature_140_residues
TAALTIGELGRRTGTKVETVRYYEKIGLLALPKRTRGNYRAYGENDVARLSFIRRTRDLGFSIDQVRALLSLAGDESRDC
ATIDAIASTHLGEIDRKLADLAVLRREIAALVASCEGGTIGQCRILEALAPIAGRRPPDI

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=38.5826771653543, Blast_Score=87, Evalue=3e-19,
Organism=Escherichia coli, GI1786695, Length=133, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 15369; Mature: 15238

Theoretical pI: Translated: 9.26; Mature: 9.26

Prosite motif: PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAALTIGELGRRTGTKVETVRYYEKIGLLALPKRTRGNYRAYGENDVARLSFIRRTRDL
CCCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GFSIDQVRALLSLAGDESRDCATIDAIASTHLGEIDRKLADLAVLRREIAALVASCEGGT
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IGQCRILEALAPIAGRRPPDI
CCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAALTIGELGRRTGTKVETVRYYEKIGLLALPKRTRGNYRAYGENDVARLSFIRRTRDL
CCCCHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
GFSIDQVRALLSLAGDESRDCATIDAIASTHLGEIDRKLADLAVLRREIAALVASCEGGT
CCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IGQCRILEALAPIAGRRPPDI
CCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]