Click here to switch to the map view.

The map label for this gene is ctrA [H]

Identifier: 103486056

GI number: 103486056

Start: 576804

End: 577511

Strand: Direct

Name: ctrA [H]

Synonym: Sala_0563

Alternate gene names: 103486056

Gene position: 576804-577511 (Clockwise)

Preceding gene: 103486055

Following gene: 103486075

Centisome position: 17.24

GC content: 59.6

Gene sequence:

>708_bases
ATGCGCGTACTGCTGATCGAGGACGAGCCGACGACCGCGAAAGCGATCGACACGATGCTCACGACCGAGGGCTTCAACGT
CTACACCACCGATCTGGGCGAAGAGGGCCTCGATCTGGGTAAGCTCTATGATTACGACATCATCCTGCTCGACCTGAATC
TGCCCGACATGCACGGCTATGACGTGCTCAAGAAGCTCCGCACCGCCAAGGTGCAGACGCCGGTGCTGATCCTGTCGGGC
ATTTCGGAAATGGACAGCAAGGTGCGTTCGTTCGGCTTCGGCGCCGACGATTATGTCACCAAACCCTTCCACCGCGACGA
ACTGGTCGCCCGCATTCACGCGGTCGTCCGCCGGTCGAAAGGCCACAGCCAGAGCGTTATCAAGACGGGCAAGCTCGCGG
TCAATCTGGATACCAAGACGGTCGAAGTCGACAGCATCCGGGTGCATCTGACCGGCAAGGAATATCAGATGCTGGAGCTG
CTCAGCCTGCGCAAGGGCACCACGCTTACCAAGGAAATGTTCCTGAACCACCTGTACGGCGGCATGGACGAGCCCGAGCT
GAAGATCATCGACGTCTTCATCTGCAAGCTGCGCAAGAAGCTCGCACTGGCGTGCGGCGGCGACAATTATATCGAGACGG
TCTGGGGCCGCGGTTATGTCCTTCGCGACATCGACGACGAAGGCAATGAGGTGCGCCGCGTAGCCTGA

Upstream 100 bases:

>100_bases
ATGTTCCGGCAGTCCTGCAACGGGGGTTGGTCGGTGACATCCTTGATGATCATGCGATCGGTTCGCGGGATCATCGTGGG
AAACAGTCAAGGGGTGCCCA

Downstream 100 bases:

>100_bases
CGCCGCGCGCACCGCACACAAGTTAACCGAGGGAAGCCGGCGCGGAGCAATCCGCGCCGGTTTTCCTTTTGAGCCAATAT
CATGTCATCGCGCTCTAACG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: Response regulator SokA [H]

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRVLLIEDEPTTAKAIDTMLTTEGFNVYTTDLGEEGLDLGKLYDYDIILLDLNLPDMHGYDVLKKLRTAKVQTPVLILSG
ISEMDSKVRSFGFGADDYVTKPFHRDELVARIHAVVRRSKGHSQSVIKTGKLAVNLDTKTVEVDSIRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLALACGGDNYIETVWGRGYVLRDIDDEGNEVRRVA

Sequences:

>Translated_235_residues
MRVLLIEDEPTTAKAIDTMLTTEGFNVYTTDLGEEGLDLGKLYDYDIILLDLNLPDMHGYDVLKKLRTAKVQTPVLILSG
ISEMDSKVRSFGFGADDYVTKPFHRDELVARIHAVVRRSKGHSQSVIKTGKLAVNLDTKTVEVDSIRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLALACGGDNYIETVWGRGYVLRDIDDEGNEVRRVA
>Mature_235_residues
MRVLLIEDEPTTAKAIDTMLTTEGFNVYTTDLGEEGLDLGKLYDYDIILLDLNLPDMHGYDVLKKLRTAKVQTPVLILSG
ISEMDSKVRSFGFGADDYVTKPFHRDELVARIHAVVRRSKGHSQSVIKTGKLAVNLDTKTVEVDSIRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLALACGGDNYIETVWGRGYVLRDIDDEGNEVRRVA

Specific function: Forms part of a two-component regulatory system CtrA/CckA that controls multiple events in the cell cycle, including cell division, stalk synthesis and cell cycle-specific transcription. Binds to a group of cell cycle-regulated promoters critical for DNA

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.4801762114537, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=34.375, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI87082012, Length=219, Percent_Identity=34.703196347032, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.4841628959276, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=32.1266968325792, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=29.0748898678414, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.8370044052863, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.5936073059361, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=33.6244541484716, Blast_Score=103, Evalue=7e-24,
Organism=Escherichia coli, GI1786599, Length=222, Percent_Identity=32.4324324324324, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.6306306306306, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788394, Length=227, Percent_Identity=29.0748898678414, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=32.7102803738318, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=23.8938053097345, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25.625, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790299, Length=139, Percent_Identity=28.0575539568345, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26508; Mature: 26508

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDEPTTAKAIDTMLTTEGFNVYTTDLGEEGLDLGKLYDYDIILLDLNLPDMHGY
CEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECEEEEEEEECCCCCCCH
DVLKKLRTAKVQTPVLILSGISEMDSKVRSFGFGADDYVTKPFHRDELVARIHAVVRRSK
HHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GHSQSVIKTGKLAVNLDTKTVEVDSIRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCCHHHEECCCEEEEECCCEEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLALACGGDNYIETVWGRGYVLRDIDDEGNEVRRVA
CCCCCCHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCEEEEECCCCCCCEECCC
>Mature Secondary Structure
MRVLLIEDEPTTAKAIDTMLTTEGFNVYTTDLGEEGLDLGKLYDYDIILLDLNLPDMHGY
CEEEEEECCCCHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECEEEEEEEECCCCCCCH
DVLKKLRTAKVQTPVLILSGISEMDSKVRSFGFGADDYVTKPFHRDELVARIHAVVRRSK
HHHHHHHHHHCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
GHSQSVIKTGKLAVNLDTKTVEVDSIRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CCCHHHEECCCEEEEECCCEEEEEEEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLALACGGDNYIETVWGRGYVLRDIDDEGNEVRRVA
CCCCCCHHHHHHHHHHHHHHHEEEECCCCCEEECCCCCEEEEECCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8548829 [H]