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The map label for this gene is ligD [H]

Identifier: 103485868

GI number: 103485868

Start: 385276

End: 386121

Strand: Direct

Name: ligD [H]

Synonym: Sala_0373

Alternate gene names: 103485868

Gene position: 385276-386121 (Clockwise)

Preceding gene: 103485865

Following gene: 103485870

Centisome position: 11.52

GC content: 65.72

Gene sequence:

>846_bases
ATGGACTTTCAGGGCAAGAGCGTCGTGATCACCGGTGGTGCGACAGGCATCGGTTTTGCGCTGGCGAAGCGGATCGGGAC
GGCAGGCGCGCGGATCATCCTGTTTGAACCGCGTGAGGAAAGACTTGCCGCGGCCGTCGAGGCGCTGGCGCCGTTCGGGG
TCAATGCGTGCGCGTTCGCGGGTGATGTCACCGATGCCGCTGCGGTAGAGGCGCTCGCCGATTTCGCCTGGGCAACGCAT
GGCCGCGCCGACGCAATCATCGCCAACGCCGGGGTCGGCGGGGTTCGGACCGAGATACTCGATACCGACGATGCCGCGGC
GCGCGCGCTGATCGAGGTCAACTTCTGGGGCGTATGGAATTGCGTCCGCACCTTCGGCCGGCGCTTTCAGGGCGATGGCC
TCCCGTCGGCGATCTACGCGACAGCGTCGGAGAATGGCCTGTTCAACGCGGTGCGCCGGAACGGCGGCATCTATGTCGCC
AGCAAGCATGCCGTGATTGGCCTGATGGACACGCTGCGCAACGAGGCGCCGGACACGATCGAGGTCGGCGTGATCATTCC
CGGCTGGGTGAAGTCCGACATGACGCGCCACGCCGATGCGGCGATGGACGCCGACGTCTTTGCGAATCGCATCGTGCCGC
AGATGGAGGCAGGCCAATTCTACCTCGTCAGCCATCCGTACAACGTCGTGCGGATGGAAGAGCGCTGGGCCGAGGCCTAT
GCCGCCTTTGCCAAATACGCCCCGCGCGAGCCCGGCGATGACGCGATGGACGTCGCGCTATTCATGGAACGCATGCGCGC
CGAGCGCGAAGGCCTTACACCCCCGCCAGCAACCCCTCATCCTTGA

Upstream 100 bases:

>100_bases
GACATGGGCGAGGGAGCGAGAGTCAAGGGCATCGGTGATCCCCTGCTGCGTTGACGCTGATGGCGCAGCGCGCCTAGCCT
TGCAAGAAAGGAGAGAAGCG

Downstream 100 bases:

>100_bases
TCCGCTTTTGCCACAGCTTCGGCGCGTTGACGTGGACGTTCTGGCCTTCGCTGTCGACCGCGACGGTGACGGGGAAGTCC
TGCACCTCGAACTCGTAGAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MDFQGKSVVITGGATGIGFALAKRIGTAGARIILFEPREERLAAAVEALAPFGVNACAFAGDVTDAAAVEALADFAWATH
GRADAIIANAGVGGVRTEILDTDDAAARALIEVNFWGVWNCVRTFGRRFQGDGLPSAIYATASENGLFNAVRRNGGIYVA
SKHAVIGLMDTLRNEAPDTIEVGVIIPGWVKSDMTRHADAAMDADVFANRIVPQMEAGQFYLVSHPYNVVRMEERWAEAY
AAFAKYAPREPGDDAMDVALFMERMRAEREGLTPPPATPHP

Sequences:

>Translated_281_residues
MDFQGKSVVITGGATGIGFALAKRIGTAGARIILFEPREERLAAAVEALAPFGVNACAFAGDVTDAAAVEALADFAWATH
GRADAIIANAGVGGVRTEILDTDDAAARALIEVNFWGVWNCVRTFGRRFQGDGLPSAIYATASENGLFNAVRRNGGIYVA
SKHAVIGLMDTLRNEAPDTIEVGVIIPGWVKSDMTRHADAAMDADVFANRIVPQMEAGQFYLVSHPYNVVRMEERWAEAY
AAFAKYAPREPGDDAMDVALFMERMRAEREGLTPPPATPHP
>Mature_281_residues
MDFQGKSVVITGGATGIGFALAKRIGTAGARIILFEPREERLAAAVEALAPFGVNACAFAGDVTDAAAVEALADFAWATH
GRADAIIANAGVGGVRTEILDTDDAAARALIEVNFWGVWNCVRTFGRRFQGDGLPSAIYATASENGLFNAVRRNGGIYVA
SKHAVIGLMDTLRNEAPDTIEVGVIIPGWVKSDMTRHADAAMDADVFANRIVPQMEAGQFYLVSHPYNVVRMEERWAEAY
AAFAKYAPREPGDDAMDVALFMERMRAEREGLTPPPATPHP

Specific function: Catalyzes the C alpha dehydrogenation of arylglycerol- beta-aryl ether (C alpha alcohol type) (compound IV) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI87082100, Length=204, Percent_Identity=31.8627450980392, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787335, Length=223, Percent_Identity=28.6995515695067, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790717, Length=195, Percent_Identity=32.3076923076923, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=196, Percent_Identity=30.6122448979592, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=199, Percent_Identity=25.1256281407035, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=198, Percent_Identity=26.2626262626263, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17567345, Length=197, Percent_Identity=26.3959390862944, Blast_Score=64, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30112; Mature: 30112

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFQGKSVVITGGATGIGFALAKRIGTAGARIILFEPREERLAAAVEALAPFGVNACAFA
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHCC
GDVTDAAAVEALADFAWATHGRADAIIANAGVGGVRTEILDTDDAAARALIEVNFWGVWN
CCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCHHHEEEEEEECHHHHH
CVRTFGRRFQGDGLPSAIYATASENGLFNAVRRNGGIYVASKHAVIGLMDTLRNEAPDTI
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCEE
EVGVIIPGWVKSDMTRHADAAMDADVFANRIVPQMEAGQFYLVSHPYNVVRMEERWAEAY
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHH
AAFAKYAPREPGDDAMDVALFMERMRAEREGLTPPPATPHP
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDFQGKSVVITGGATGIGFALAKRIGTAGARIILFEPREERLAAAVEALAPFGVNACAFA
CCCCCCEEEEECCCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCCHHHCC
GDVTDAAAVEALADFAWATHGRADAIIANAGVGGVRTEILDTDDAAARALIEVNFWGVWN
CCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEECCCCHHHEEEEEEECHHHHH
CVRTFGRRFQGDGLPSAIYATASENGLFNAVRRNGGIYVASKHAVIGLMDTLRNEAPDTI
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCEE
EVGVIIPGWVKSDMTRHADAAMDADVFANRIVPQMEAGQFYLVSHPYNVVRMEERWAEAY
EEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEHHHHHHHHH
AAFAKYAPREPGDDAMDVALFMERMRAEREGLTPPPATPHP
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1744051; 8495726; 7764263 [H]