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The map label for this gene is yycF [H]

Identifier: 158340554

GI number: 158340554

Start: 91704

End: 92417

Strand: Reverse

Name: yycF [H]

Synonym: AM1_C0101

Alternate gene names: 158340554

Gene position: 92417-91704 (Counterclockwise)

Preceding gene: 158340555

Following gene: 158340553

Centisome position: 33.84

GC content: 45.52

Gene sequence:

>714_bases
ATGAGGAGTCATCCGCCTGCCATTTTGGTCGTGGATGACGAAGCCAGCATTCGACGAGTTTTAAGCACACGCCTTTCCAA
AATAGGTTACCAAGTTTACACCGCTGCTGATGGGGTGGAAGCACTCGATGTCTTCTATGATCAACGTCCTGACCTGATTA
TCTTAGATGTGATGATGCCTAAGTTGGACGGTTACGGGGTCTGTCAAGCAGTTCGCAAGGCATCAAGAGTCCCCATTATT
ATGCTAACTGCGCTTTCCGATGTCGTTGACCGAATTACTGGCTTAGAAATGGGTGCCGATGATTATGTCGTTAAGCCATT
TTCATTGAAGGAGCTGGAATCGCGTGTTAGGTCTATTCTTCGCCGAATGGAGACTACAAAACCTCTTCCTTTTCATCATC
AAAGTAATGGTGTCATTCGATTTGGTTCAATAACAGTCGATACCAACAAAAGACAGGTTTTCAAGGGACGTAGCCGTATT
TCCCTTACCCATATGGAATTTAGTGTATTGGAATTGTTAGCGACCCATCCAGGAGAACCTATTTCGCGGTCAGAGTTTTT
GCATAAAGTATGGGGATATAGCCATGAGGCTAACGTTGACACTCAGGTCGTTGATATTCATATCTCACACTTACGTCGCA
AACTTGGGGATAGCAGCGGCAACCCCAAACTAATTCATACCGTACACGGGGTAGGTTATACCCTGAAGCCCTAG

Upstream 100 bases:

>100_bases
TTAAACTGCCCAGACATTGCATCTATCAATGATTCTTGCTTACTGAATATTCTGTTTTATCTGAGACGCGATTAATCCGA
ACATAGAATTAATGAATAGT

Downstream 100 bases:

>100_bases
AGAGTTTAGGCCAAGCTCACTTCTATGGTTACCCGCTTGAGCACCACCCAAATGGTGTGTTAGCTCTAGCTTCATAGCAG
AAAATCTCACAAATCCATAA

Product: two-component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MRSHPPAILVVDDEASIRRVLSTRLSKIGYQVYTAADGVEALDVFYDQRPDLIILDVMMPKLDGYGVCQAVRKASRVPII
MLTALSDVVDRITGLEMGADDYVVKPFSLKELESRVRSILRRMETTKPLPFHHQSNGVIRFGSITVDTNKRQVFKGRSRI
SLTHMEFSVLELLATHPGEPISRSEFLHKVWGYSHEANVDTQVVDIHISHLRRKLGDSSGNPKLIHTVHGVGYTLKP

Sequences:

>Translated_237_residues
MRSHPPAILVVDDEASIRRVLSTRLSKIGYQVYTAADGVEALDVFYDQRPDLIILDVMMPKLDGYGVCQAVRKASRVPII
MLTALSDVVDRITGLEMGADDYVVKPFSLKELESRVRSILRRMETTKPLPFHHQSNGVIRFGSITVDTNKRQVFKGRSRI
SLTHMEFSVLELLATHPGEPISRSEFLHKVWGYSHEANVDTQVVDIHISHLRRKLGDSSGNPKLIHTVHGVGYTLKP
>Mature_237_residues
MRSHPPAILVVDDEASIRRVLSTRLSKIGYQVYTAADGVEALDVFYDQRPDLIILDVMMPKLDGYGVCQAVRKASRVPII
MLTALSDVVDRITGLEMGADDYVVKPFSLKELESRVRSILRRMETTKPLPFHHQSNGVIRFGSITVDTNKRQVFKGRSRI
SLTHMEFSVLELLATHPGEPISRSEFLHKVWGYSHEANVDTQVVDIHISHLRRKLGDSSGNPKLIHTVHGVGYTLKP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=38.0952380952381, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=37.3913043478261, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082012, Length=228, Percent_Identity=36.8421052631579, Blast_Score=147, Evalue=6e-37,
Organism=Escherichia coli, GI1786911, Length=227, Percent_Identity=36.5638766519824, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=35.8078602620087, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=35.0877192982456, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=34.4978165938865, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=36.3636363636364, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=36.9098712446352, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=35.8078602620087, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=31.4410480349345, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI145693140, Length=239, Percent_Identity=31.3807531380753, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=31.0043668122271, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1787375, Length=230, Percent_Identity=28.695652173913, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788550, Length=129, Percent_Identity=37.984496124031, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI145693157, Length=103, Percent_Identity=40.7766990291262, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790299, Length=123, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=32.4561403508772, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788191, Length=127, Percent_Identity=32.2834645669291, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788713, Length=114, Percent_Identity=35.9649122807018, Blast_Score=66, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=108, Percent_Identity=35.1851851851852, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26650; Mature: 26650

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHPPAILVVDDEASIRRVLSTRLSKIGYQVYTAADGVEALDVFYDQRPDLIILDVMMP
CCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEEEECC
KLDGYGVCQAVRKASRVPIIMLTALSDVVDRITGLEMGADDYVVKPFSLKELESRVRSIL
CCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHH
RRMETTKPLPFHHQSNGVIRFGSITVDTNKRQVFKGRSRISLTHMEFSVLELLATHPGEP
HHHHCCCCCCCEECCCCEEEEEEEEEECCCHHHHCCCCEEEEEHHHHHHHHHHHHCCCCC
ISRSEFLHKVWGYSHEANVDTQVVDIHISHLRRKLGDSSGNPKLIHTVHGVGYTLKP
CCHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCEEECC
>Mature Secondary Structure
MRSHPPAILVVDDEASIRRVLSTRLSKIGYQVYTAADGVEALDVFYDQRPDLIILDVMMP
CCCCCCEEEEECCHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHCCCCCEEEEEEECC
KLDGYGVCQAVRKASRVPIIMLTALSDVVDRITGLEMGADDYVVKPFSLKELESRVRSIL
CCCCCHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHH
RRMETTKPLPFHHQSNGVIRFGSITVDTNKRQVFKGRSRISLTHMEFSVLELLATHPGEP
HHHHCCCCCCCEECCCCEEEEEEEEEECCCHHHHCCCCEEEEEHHHHHHHHHHHHCCCCC
ISRSEFLHKVWGYSHEANVDTQVVDIHISHLRRKLGDSSGNPKLIHTVHGVGYTLKP
CCHHHHHHHHHCCCCCCCCCEEEEEEEHHHHHHHHCCCCCCCEEEEEEECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]