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The map label for this gene is insK [C]

Identifier: 158340535

GI number: 158340535

Start: 78542

End: 79390

Strand: Reverse

Name: insK [C]

Synonym: AM1_C0080

Alternate gene names: 158340535

Gene position: 79390-78542 (Counterclockwise)

Preceding gene: 158340536

Following gene: 158340532

Centisome position: 29.07

GC content: 42.4

Gene sequence:

>849_bases
ATGGTAAATCAACTCAAAGAACACTATCCCATTCAGATGATTTGTAATGTGATTGGATACAGTAGAAGTCGATATTACTA
CCATCAAAATCCAGGGAAGGAAAATCGGAAAGAAGTAATTCTTAAATCTGCGATTGCAGATGTAGCAGGTCGATATCCGA
CCCATGGCTATCGGCGTATTACTCAGCAATTACGTCGTGAAGGCCACACCGTCAATCACAAGCGAGTCAGTCGTTTGATG
CGAGGAATGGGGTTACTTGCTAAACAGCGGGTCCAGCGGAAGCGAACCACCAATAGTGTTCATGGGTACAAACGATATCC
TAATCTAGTGAAGGCCCTAACGATGGTGCGTCCCAACCAAGTATGGGTAGCCGATATCACCTATATCCGACTCCGAGAAG
AGTTTGTGTACCTAGCGGTATTGATGGATGTCTTTACGCGGGGAATTCGGGGTTGGCATTTGGATTGGACGATGGAAAAG
AGCTTGACGATTACAGCCCTGGAAAAAGCTTTGCTTGGCCACACCCCAGAGATTCATCATTCAGATCAAGGTGTCCAATA
TGCTGCAAATGACTATGTCAAAATGCTGGAGGATAACGATGTCAAAATCAGTATGGCTGCAGTAGGAAAAGCCTATGAAA
ATGGTTTTGCAGAACGACTGATGAGAACCATTAAAGAAGAGGAAGTTGACTTATCAGAATATCGAAATTTTAGAGAGGTC
AATGAACGAATAGAAATGTTCTTGGAAGAGGTATACATGAAGAAGAGAATTCATTCATCATTGAGCTATTTAACACCGAG
TGAATTTGAAGAAAAGTGGAGGTATGAACAAGAGAATATTCAGATGTGA

Upstream 100 bases:

>100_bases
AACGAATTGCTGAATTGGAGCGGATGATTGGTCGATTAACGATGGAGCTAGAAGTAGCAAAAAAGGCTTCCGACATGTGG
AATCTCAACGAAAATATGAA

Downstream 100 bases:

>100_bases
TACATGTTGTGTGGTTCTATCTCATTCCTGATTTTACTGTCCAAGTTCAGGGGTGTTTAATGTCAATTAGATAGGCCAAA
CTTTTTGGTTCTAACTTCAT

Product: integrase, catalytic region

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MVNQLKEHYPIQMICNVIGYSRSRYYYHQNPGKENRKEVILKSAIADVAGRYPTHGYRRITQQLRREGHTVNHKRVSRLM
RGMGLLAKQRVQRKRTTNSVHGYKRYPNLVKALTMVRPNQVWVADITYIRLREEFVYLAVLMDVFTRGIRGWHLDWTMEK
SLTITALEKALLGHTPEIHHSDQGVQYAANDYVKMLEDNDVKISMAAVGKAYENGFAERLMRTIKEEEVDLSEYRNFREV
NERIEMFLEEVYMKKRIHSSLSYLTPSEFEEKWRYEQENIQM

Sequences:

>Translated_282_residues
MVNQLKEHYPIQMICNVIGYSRSRYYYHQNPGKENRKEVILKSAIADVAGRYPTHGYRRITQQLRREGHTVNHKRVSRLM
RGMGLLAKQRVQRKRTTNSVHGYKRYPNLVKALTMVRPNQVWVADITYIRLREEFVYLAVLMDVFTRGIRGWHLDWTMEK
SLTITALEKALLGHTPEIHHSDQGVQYAANDYVKMLEDNDVKISMAAVGKAYENGFAERLMRTIKEEEVDLSEYRNFREV
NERIEMFLEEVYMKKRIHSSLSYLTPSEFEEKWRYEQENIQM
>Mature_282_residues
MVNQLKEHYPIQMICNVIGYSRSRYYYHQNPGKENRKEVILKSAIADVAGRYPTHGYRRITQQLRREGHTVNHKRVSRLM
RGMGLLAKQRVQRKRTTNSVHGYKRYPNLVKALTMVRPNQVWVADITYIRLREEFVYLAVLMDVFTRGIRGWHLDWTMEK
SLTITALEKALLGHTPEIHHSDQGVQYAANDYVKMLEDNDVKISMAAVGKAYENGFAERLMRTIKEEEVDLSEYRNFREV
NERIEMFLEEVYMKKRIHSSLSYLTPSEFEEKWRYEQENIQM

Specific function: Involved in the transposition of the insertion sequence is150 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=269, Percent_Identity=31.5985130111524, Blast_Score=131, Evalue=7e-31,
Organism=Escherichia coli, GI1789981, Length=277, Percent_Identity=31.0469314079422, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1788405, Length=281, Percent_Identity=28.1138790035587, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1787263, Length=281, Percent_Identity=28.1138790035587, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786753, Length=281, Percent_Identity=28.1138790035587, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786570, Length=281, Percent_Identity=28.1138790035587, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1786490, Length=281, Percent_Identity=28.1138790035587, Blast_Score=117, Evalue=7e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33526; Mature: 33526

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNQLKEHYPIQMICNVIGYSRSRYYYHQNPGKENRKEVILKSAIADVAGRYPTHGYRRI
CCCCHHHHCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
TQQLRREGHTVNHKRVSRLMRGMGLLAKQRVQRKRTTNSVHGYKRYPNLVKALTMVRPNQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC
VWVADITYIRLREEFVYLAVLMDVFTRGIRGWHLDWTMEKSLTITALEKALLGHTPEIHH
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCC
SDQGVQYAANDYVKMLEDNDVKISMAAVGKAYENGFAERLMRTIKEEEVDLSEYRNFREV
CCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NERIEMFLEEVYMKKRIHSSLSYLTPSEFEEKWRYEQENIQM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MVNQLKEHYPIQMICNVIGYSRSRYYYHQNPGKENRKEVILKSAIADVAGRYPTHGYRRI
CCCCHHHHCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
TQQLRREGHTVNHKRVSRLMRGMGLLAKQRVQRKRTTNSVHGYKRYPNLVKALTMVRPNQ
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC
VWVADITYIRLREEFVYLAVLMDVFTRGIRGWHLDWTMEKSLTITALEKALLGHTPEIHH
EEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHCCCCCCCC
SDQGVQYAANDYVKMLEDNDVKISMAAVGKAYENGFAERLMRTIKEEEVDLSEYRNFREV
CCCCCHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
NERIEMFLEEVYMKKRIHSSLSYLTPSEFEEKWRYEQENIQM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]