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The map label for this gene is mtnU [H]

Identifier: 158340500

GI number: 158340500

Start: 51334

End: 52143

Strand: Direct

Name: mtnU [H]

Synonym: AM1_C0045

Alternate gene names: 158340500

Gene position: 51334-52143 (Clockwise)

Preceding gene: 158340499

Following gene: 158340502

Centisome position: 18.8

GC content: 33.7

Gene sequence:

>810_bases
ATGAAAGTAGGTTTTATTCAATTCTCACCTATTCTCGGTAAGCCAACTCAAACTTTAGAACGACTAGAATACTTAATTGA
TAAAGGTAAACATTCAGATATTCTTGTGCTGCCAGAATTGTGTAATTCTGGATATGCCTTTAATTCTAGGCAACAAGCTC
TAAATTCAAGTGAATCTGTCGCTGATAGTAAATTTATTCGTTTTCTTCACGAAAAGTCAAATAAATATAATCTATATATC
GTGTCAGGTTTTTGTGAAAAATCTGACAAGGATTTGTATAATTCTTCTTTTCTAGTTGGACCAAATGAATATATAGAAGT
TTATAGGAAGTCACATCTTTTTCTGAATGAAAAAGATTTTTTTTCTCCTGGGAATACAGATTATTCTGTCTATGACATTG
GTATCTGTAAAATAGGGATGTTGATTTGTTTTGATTGGGTGTTCCCTGAAGCATGGAGAATCTTAGCTCTTAAAGGTGCT
GATATTATTTGTCATCCCTCTAATATTGTTCTACCTGATTTGTGCCAAAAGACCATACCTGGCCACTCTATATGCAATCG
AATGTTCATCGTAACAGCTAACCGTATAGGCACTGAGGATAATCTTACGTTTACAGGTAGTTCAATTATTTGTGACCCTA
GAGGTAATATTCTGACCCAAGCTTCGGATGATCAAGAAGAAGTAATGATTTCAGACATTGATTTGAATTTAGCTAGGGAT
AAATCAATTACATCTAGGAATCATATCTTTCTTGATAGACGGCCAGATAAGTATTTGGATATAGCGAAAGCAATTGAAGA
ATCAGTATAG

Upstream 100 bases:

>100_bases
CTGACATGAGAAGAGTTGTTGATCCAAATTTATATAATATTGGATTACTTCAGTTTATTTAATTACCCTAAAAACTATTC
TACTTCTTGGGCTTAATGAA

Downstream 100 bases:

>100_bases
GTAACATCTAGTTTTGATTTCTAATCCGTTATCACTTTATTTGTTGGAACTACTAAAATGACCTAAATATCTACCGAAAA
TTTTGAAATTATTTCCTAGA

Product: carbon-nitrogen hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MKVGFIQFSPILGKPTQTLERLEYLIDKGKHSDILVLPELCNSGYAFNSRQQALNSSESVADSKFIRFLHEKSNKYNLYI
VSGFCEKSDKDLYNSSFLVGPNEYIEVYRKSHLFLNEKDFFSPGNTDYSVYDIGICKIGMLICFDWVFPEAWRILALKGA
DIICHPSNIVLPDLCQKTIPGHSICNRMFIVTANRIGTEDNLTFTGSSIICDPRGNILTQASDDQEEVMISDIDLNLARD
KSITSRNHIFLDRRPDKYLDIAKAIEESV

Sequences:

>Translated_269_residues
MKVGFIQFSPILGKPTQTLERLEYLIDKGKHSDILVLPELCNSGYAFNSRQQALNSSESVADSKFIRFLHEKSNKYNLYI
VSGFCEKSDKDLYNSSFLVGPNEYIEVYRKSHLFLNEKDFFSPGNTDYSVYDIGICKIGMLICFDWVFPEAWRILALKGA
DIICHPSNIVLPDLCQKTIPGHSICNRMFIVTANRIGTEDNLTFTGSSIICDPRGNILTQASDDQEEVMISDIDLNLARD
KSITSRNHIFLDRRPDKYLDIAKAIEESV
>Mature_269_residues
MKVGFIQFSPILGKPTQTLERLEYLIDKGKHSDILVLPELCNSGYAFNSRQQALNSSESVADSKFIRFLHEKSNKYNLYI
VSGFCEKSDKDLYNSSFLVGPNEYIEVYRKSHLFLNEKDFFSPGNTDYSVYDIGICKIGMLICFDWVFPEAWRILALKGA
DIICHPSNIVLPDLCQKTIPGHSICNRMFIVTANRIGTEDNLTFTGSSIICDPRGNILTQASDDQEEVMISDIDLNLARD
KSITSRNHIFLDRRPDKYLDIAKAIEESV

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=250, Percent_Identity=26.4, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786412, Length=243, Percent_Identity=23.8683127572016, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17533173, Length=237, Percent_Identity=27.8481012658228, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323383, Length=286, Percent_Identity=26.2237762237762, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17933642, Length=250, Percent_Identity=26.8, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21358471, Length=278, Percent_Identity=23.3812949640288, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355835, Length=250, Percent_Identity=25.6, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30556; Mature: 30556

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGFIQFSPILGKPTQTLERLEYLIDKGKHSDILVLPELCNSGYAFNSRQQALNSSESV
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHCCCHHHH
ADSKFIRFLHEKSNKYNLYIVSGFCEKSDKDLYNSSFLVGPNEYIEVYRKSHLFLNEKDF
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHCEEECCCCC
FSPGNTDYSVYDIGICKIGMLICFDWVFPEAWRILALKGADIICHPSNIVLPDLCQKTIP
CCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCCHHHHHHCCC
GHSICNRMFIVTANRIGTEDNLTFTGSSIICDPRGNILTQASDDQEEVMISDIDLNLARD
CHHHHCEEEEEEECCCCCCCCEEEECCEEEECCCCCEEECCCCCCCEEEEEECCEEECCC
KSITSRNHIFLDRRPDKYLDIAKAIEESV
CCCCCCCCEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKVGFIQFSPILGKPTQTLERLEYLIDKGKHSDILVLPELCNSGYAFNSRQQALNSSESV
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHCCCCCCCCHHHHCCCHHHH
ADSKFIRFLHEKSNKYNLYIVSGFCEKSDKDLYNSSFLVGPNEYIEVYRKSHLFLNEKDF
HHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCEEEECCHHHHHHHHHHCEEECCCCC
FSPGNTDYSVYDIGICKIGMLICFDWVFPEAWRILALKGADIICHPSNIVLPDLCQKTIP
CCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCEEEEEEECCEEEECCCCCCCHHHHHHCCC
GHSICNRMFIVTANRIGTEDNLTFTGSSIICDPRGNILTQASDDQEEVMISDIDLNLARD
CHHHHCEEEEEEECCCCCCCCEEEECCEEEECCCCCEEECCCCCCCEEEEEECCEEECCC
KSITSRNHIFLDRRPDKYLDIAKAIEESV
CCCCCCCCEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]