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The map label for this gene is cfa [H]

Identifier: 148243671

GI number: 148243671

Start: 46128

End: 47306

Strand: Reverse

Name: cfa [H]

Synonym: Acry_3143

Alternate gene names: 148243671

Gene position: 47306-46128 (Counterclockwise)

Preceding gene: 148243672

Following gene: 148243670

Centisome position: 23.24

GC content: 61.41

Gene sequence:

>1179_bases
ATGTTTATTTCGATATTGAAATCGCTCGTGCACGACGGCAGCCTCGGCGTGATCGATGCCGGAGGCCGCTTGCACAAGGT
CGGCGACGGCTCCGCGCCCAGCGCGACAATCAGGTTGATGTCGAAGGCCATGGAGTATCGGCTTGCCGTCAATCCGGCGC
TCACGGTGGGCGAGGCATACATGAACGGCGCACTGCGGATTGAAGAGGGCACGCTCTATGACTTCGCTGCCGTGATCGGG
CGCAATGCAAGTCAGGCGCGGTCGCTGCCATGGCTTGCGCTGCTCAACCGGGCCCGGCGCCACGTGCGGCAGTCGAACCC
GATGTCGCGGGCGCGGCGCAACGTCGCCCATCATTACGATTTGTCGAACGAATTCTATGCGATGTTTCTCGACCGGGACA
TGCAGTATTCCTGCGCCTATTTCCACTCGCCGGACGATGATCTGGAGACGGCGCAGGCGAACAAGAAGCGGCACATCATG
GCGAAGCTGCTGCTCGACCGGCGCGGACTCCGGGTTCTCGACATCGGCTCAGGCTGGGGCGGCATGTGCCTCGATATCGC
GACGCACTGCGATGCCGAGGTTACGGGCGTGACACTCAGCACCGAGCAGTACAGACTGAGCGTCGAGCGGGCCGCGGCAG
CCGGGGTTGCCGAGCGCGTGGGGTTTCATCTGGAGGATTACCGCGACGAAGCGGGTCCTTATGACCGCATCGTTTCGGTC
GGGATGTTCGAGCATGTGGGAAAGCGGAACTATGCAGAGTTCTTTGCGAAGCTGCGCGACCTGCTGACGGATGACGGCGT
CGCGTTGATCCACACGATCGGGTATTCGGATCATCCCGCGCCGATCAATCCGTTTCTGCGGAAATACATCTTTCCCGGGG
CCGACCTGCCATCCCTGTCGGAGATTGCCGCCGCTGTGGAGTGGAGCGGCCTGATCATAACCGATGTTGAGGTACTGCGG
CTGCATTATGCCGAGACGCTGCGGCACTGGCGCGAGCGTTTCGTCGCGCGGCGGGCGGATGTGGTGCGCCTCTATGACGA
GCGGTTCTACCGGATGTGGGAATTCTATCTCGTCCTGTGCGAGATCGGCTTCCGGATGCGGACGAACGTAGTGTTCCAGA
TCCAGTTGACAAAGCGGCTGGACGCGTTGCCAATTCGCCGTGATTACATGGTCGATTAG

Upstream 100 bases:

>100_bases
ACCATGAACGGTTGCGAACCGTGGCTCATTGGCGATATCATTGTGTCGGACGAGCCAATCTCCCGTTGGCATATGGAAAG
ACGCGAACCGAACGGGCGCA

Downstream 100 bases:

>100_bases
CTTCCAGTTCGACTGGCGACCAGCTTCGTGCTGCCGGACGGATAGCACGACGTCTCAAGTTGAATTTAGGTGGTCACCTG
TGAACTATGTGATCTGGCGG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MFISILKSLVHDGSLGVIDAGGRLHKVGDGSAPSATIRLMSKAMEYRLAVNPALTVGEAYMNGALRIEEGTLYDFAAVIG
RNASQARSLPWLALLNRARRHVRQSNPMSRARRNVAHHYDLSNEFYAMFLDRDMQYSCAYFHSPDDDLETAQANKKRHIM
AKLLLDRRGLRVLDIGSGWGGMCLDIATHCDAEVTGVTLSTEQYRLSVERAAAAGVAERVGFHLEDYRDEAGPYDRIVSV
GMFEHVGKRNYAEFFAKLRDLLTDDGVALIHTIGYSDHPAPINPFLRKYIFPGADLPSLSEIAAAVEWSGLIITDVEVLR
LHYAETLRHWRERFVARRADVVRLYDERFYRMWEFYLVLCEIGFRMRTNVVFQIQLTKRLDALPIRRDYMVD

Sequences:

>Translated_392_residues
MFISILKSLVHDGSLGVIDAGGRLHKVGDGSAPSATIRLMSKAMEYRLAVNPALTVGEAYMNGALRIEEGTLYDFAAVIG
RNASQARSLPWLALLNRARRHVRQSNPMSRARRNVAHHYDLSNEFYAMFLDRDMQYSCAYFHSPDDDLETAQANKKRHIM
AKLLLDRRGLRVLDIGSGWGGMCLDIATHCDAEVTGVTLSTEQYRLSVERAAAAGVAERVGFHLEDYRDEAGPYDRIVSV
GMFEHVGKRNYAEFFAKLRDLLTDDGVALIHTIGYSDHPAPINPFLRKYIFPGADLPSLSEIAAAVEWSGLIITDVEVLR
LHYAETLRHWRERFVARRADVVRLYDERFYRMWEFYLVLCEIGFRMRTNVVFQIQLTKRLDALPIRRDYMVD
>Mature_392_residues
MFISILKSLVHDGSLGVIDAGGRLHKVGDGSAPSATIRLMSKAMEYRLAVNPALTVGEAYMNGALRIEEGTLYDFAAVIG
RNASQARSLPWLALLNRARRHVRQSNPMSRARRNVAHHYDLSNEFYAMFLDRDMQYSCAYFHSPDDDLETAQANKKRHIM
AKLLLDRRGLRVLDIGSGWGGMCLDIATHCDAEVTGVTLSTEQYRLSVERAAAAGVAERVGFHLEDYRDEAGPYDRIVSV
GMFEHVGKRNYAEFFAKLRDLLTDDGVALIHTIGYSDHPAPINPFLRKYIFPGADLPSLSEIAAAVEWSGLIITDVEVLR
LHYAETLRHWRERFVARRADVVRLYDERFYRMWEFYLVLCEIGFRMRTNVVFQIQLTKRLDALPIRRDYMVD

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=355, Percent_Identity=37.4647887323944, Blast_Score=211, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI133904226, Length=292, Percent_Identity=31.8493150684932, Blast_Score=159, Evalue=2e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 44623; Mature: 44623

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFISILKSLVHDGSLGVIDAGGRLHKVGDGSAPSATIRLMSKAMEYRLAVNPALTVGEAY
CHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHH
MNGALRIEEGTLYDFAAVIGRNASQARSLPWLALLNRARRHVRQSNPMSRARRNVAHHYD
HCCEEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
LSNEFYAMFLDRDMQYSCAYFHSPDDDLETAQANKKRHIMAKLLLDRRGLRVLDIGSGWG
CCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
GMCLDIATHCDAEVTGVTLSTEQYRLSVERAAAAGVAERVGFHLEDYRDEAGPYDRIVSV
CHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHH
GMFEHVGKRNYAEFFAKLRDLLTDDGVALIHTIGYSDHPAPINPFLRKYIFPGADLPSLS
HHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCHH
EIAAAVEWSGLIITDVEVLRLHYAETLRHWRERFVARRADVVRLYDERFYRMWEFYLVLC
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGFRMRTNVVFQIQLTKRLDALPIRRDYMVD
HHCCEEECCEEEEEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MFISILKSLVHDGSLGVIDAGGRLHKVGDGSAPSATIRLMSKAMEYRLAVNPALTVGEAY
CHHHHHHHHHCCCCEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHEECCCHHHHHHHH
MNGALRIEEGTLYDFAAVIGRNASQARSLPWLALLNRARRHVRQSNPMSRARRNVAHHYD
HCCEEEEECCCHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCC
LSNEFYAMFLDRDMQYSCAYFHSPDDDLETAQANKKRHIMAKLLLDRRGLRVLDIGSGWG
CCCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCC
GMCLDIATHCDAEVTGVTLSTEQYRLSVERAAAAGVAERVGFHLEDYRDEAGPYDRIVSV
CHHHHHHHCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHH
GMFEHVGKRNYAEFFAKLRDLLTDDGVALIHTIGYSDHPAPINPFLRKYIFPGADLPSLS
HHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCHH
EIAAAVEWSGLIITDVEVLRLHYAETLRHWRERFVARRADVVRLYDERFYRMWEFYLVLC
HHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIGFRMRTNVVFQIQLTKRLDALPIRRDYMVD
HHCCEEECCEEEEEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]