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The map label for this gene is ascN [H]

Identifier: 145301459

GI number: 145301459

Start: 73259

End: 74596

Strand: Direct

Name: ascN [H]

Synonym: ASA_P5G076

Alternate gene names: 145301459

Gene position: 73259-74596 (Clockwise)

Preceding gene: 145301426

Following gene: 145301460

Centisome position: 47.23

GC content: 64.87

Gene sequence:

>1338_bases
ATGGCGCAGATTGTTATGACCCTCTCCCTCGACCACATCCCCGACCAGCTTCGTCACGCCATCGACGAGTGCCGCCTGAT
CCAGATCCGTGGCCGGGTCACCCAGGTGACCGGCACCCTGCTCAAGGCGGTCGTCCCCGGGGTGCGGATCGGCGAGCTCT
GCCATCTGCGCAACCCGGACAACACCCTCTCCCTGCAGGCAGAGGTGATCGGCTTTGCCCAGCATCAAGCGCTGCTCACC
CCCCTTGGCGAAATGTTCGGCATCTCCTCCAACACCGAGGTGAGCCCGACCGGTGCCATGCATCAGGTCGGGGTCGGCGA
ACATCTGCTCGGCCAGGTGCTCGATGGCCTCGGCAACCCCTTTGGCGGCGGCCATCTGCCGGAGCCCGAGGCTTGGTACC
CGGTCTATCGGGATGCGCCCGCTCCCATGAGCCGCAAGCGCATCGCCGAGCCCATTTCACTCGGTATTCGCGCCATCGAC
GGCCTGCTCACCTGCGGTGAGGGGCAACGGATGGGGATCTTCGCGGCCGCCGGTGGTGGCAAGAGCACCCTGCTGGCGTC
GCTTATTCGCAGCGCCGAGGTAGATGTCACCGTGCTGGCGCTGATCGGTGAACGGGGCCGCGAGGTGCGCGAATTTATCG
AAGCGGATCTGGGGGAAGAGGGGCTCAAGAAGGCTGTGCTGGTGGTGGCTACTTCGGATCGCCCCGCCATGGAGCGGGCC
AAGGCGGGCTTTGTCGCCACCTCCATCGCCGAGTATTTCCGCGATCAAGGCAAGCGGGTACTGCTGCTGATGGACTCCGT
CACCCGCTTTGCCCGTGCCCAGCGGGAGATTGGTCTGGCCGCTGGCGAGCCACCAACCCGACGGGGCTATCCGCCGTCGG
TGTTTGCCGCCCTGCCCCGCCTGATGGAGCGGGCCGGTCAGTCAGACAAGGGCTCCATCACTGCCCTCTATACCGTGCTG
GTAGAGGGGGATGACATGACAGAGCCGGTCGCTGACGAGACCCGCTCCATCCTCGATGGCCACATCATCCTGTCGCGCAA
ACTGGCGGCGGCCAACCACTACCCGGCCATCGACGTGCTGCGCTCCGCCAGCCGGGTGATGAACCAGATCATCGAGCCCG
AGCATCAGGCTCAGGCAGGTCGACTGCGCAGCTGGCTGGCGAAATATGAAGAGGTGGAGCTGTTGCTACAGATCGGCGAA
TACCAGAAAGGGCAGGACAAGGTAGCCGATGAGGCGATCGCCCGCATCGAGACTATTCGCCAGTGGCTCAGGCAAGGCAC
TCATGAACCCAGCTCACTGCCGGAAGCCCTCTCGACCCTAGAGGCGCTGACCCGATGA

Upstream 100 bases:

>100_bases
GCCGTGAATTTTTAGCCCGCCCCCAACGGTTTTCTAAAAAGTCCCGACTCGCGCTGAAATCCCCGTAGCCCCCCATCCCC
TATAGTGGCCGCCAGTTTCA

Downstream 100 bases:

>100_bases
TTGGCCGCCTGCAACAAATAAAAGACCTGCGGCTGGATAGGGCCGAGCAGCAGCTCGCCGCCCAGCATGCTCGGGTGCAA
CTCGCCCGCGTCCGCCAGCG

Product: type III secretion system ATPase

Products: NA

Alternate protein names: Yop proteins secretion ATPase [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MAQIVMTLSLDHIPDQLRHAIDECRLIQIRGRVTQVTGTLLKAVVPGVRIGELCHLRNPDNTLSLQAEVIGFAQHQALLT
PLGEMFGISSNTEVSPTGAMHQVGVGEHLLGQVLDGLGNPFGGGHLPEPEAWYPVYRDAPAPMSRKRIAEPISLGIRAID
GLLTCGEGQRMGIFAAAGGGKSTLLASLIRSAEVDVTVLALIGERGREVREFIEADLGEEGLKKAVLVVATSDRPAMERA
KAGFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSDKGSITALYTVL
VEGDDMTEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSASRVMNQIIEPEHQAQAGRLRSWLAKYEEVELLLQIGE
YQKGQDKVADEAIARIETIRQWLRQGTHEPSSLPEALSTLEALTR

Sequences:

>Translated_445_residues
MAQIVMTLSLDHIPDQLRHAIDECRLIQIRGRVTQVTGTLLKAVVPGVRIGELCHLRNPDNTLSLQAEVIGFAQHQALLT
PLGEMFGISSNTEVSPTGAMHQVGVGEHLLGQVLDGLGNPFGGGHLPEPEAWYPVYRDAPAPMSRKRIAEPISLGIRAID
GLLTCGEGQRMGIFAAAGGGKSTLLASLIRSAEVDVTVLALIGERGREVREFIEADLGEEGLKKAVLVVATSDRPAMERA
KAGFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSDKGSITALYTVL
VEGDDMTEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSASRVMNQIIEPEHQAQAGRLRSWLAKYEEVELLLQIGE
YQKGQDKVADEAIARIETIRQWLRQGTHEPSSLPEALSTLEALTR
>Mature_444_residues
AQIVMTLSLDHIPDQLRHAIDECRLIQIRGRVTQVTGTLLKAVVPGVRIGELCHLRNPDNTLSLQAEVIGFAQHQALLTP
LGEMFGISSNTEVSPTGAMHQVGVGEHLLGQVLDGLGNPFGGGHLPEPEAWYPVYRDAPAPMSRKRIAEPISLGIRAIDG
LLTCGEGQRMGIFAAAGGGKSTLLASLIRSAEVDVTVLALIGERGREVREFIEADLGEEGLKKAVLVVATSDRPAMERAK
AGFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSDKGSITALYTVLV
EGDDMTEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSASRVMNQIIEPEHQAQAGRLRSWLAKYEEVELLLQIGEY
QKGQDKVADEAIARIETIRQWLRQGTHEPSSLPEALSTLEALTR

Specific function: Is a component of the Yop secretion machinery using ATP, and it is either the energizer of this machinery, or part of it [H]

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm. Note=But connected to the inner membrane possibly through LcrD (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=353, Percent_Identity=30.8781869688385, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI50345984, Length=366, Percent_Identity=30.0546448087432, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI4757810, Length=366, Percent_Identity=30.0546448087432, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI19913428, Length=415, Percent_Identity=28.6746987951807, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI19913426, Length=417, Percent_Identity=27.3381294964029, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI19913424, Length=248, Percent_Identity=32.6612903225806, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1788251, Length=440, Percent_Identity=43.1818181818182, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1790170, Length=407, Percent_Identity=28.992628992629, Blast_Score=162, Evalue=6e-41,
Organism=Escherichia coli, GI1790172, Length=383, Percent_Identity=27.6762402088773, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790217, Length=223, Percent_Identity=30.4932735426009, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25144756, Length=354, Percent_Identity=30.225988700565, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71988080, Length=363, Percent_Identity=28.6501377410468, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71988063, Length=363, Percent_Identity=28.6501377410468, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17510931, Length=364, Percent_Identity=27.7472527472527, Blast_Score=131, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17570191, Length=412, Percent_Identity=26.4563106796117, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17565854, Length=348, Percent_Identity=30.7471264367816, Blast_Score=128, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI71988074, Length=340, Percent_Identity=27.0588235294118, Blast_Score=116, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319370, Length=351, Percent_Identity=31.9088319088319, Blast_Score=155, Evalue=2e-38,
Organism=Saccharomyces cerevisiae, GI6322581, Length=419, Percent_Identity=28.8782816229117, Blast_Score=153, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6319603, Length=442, Percent_Identity=29.8642533936652, Blast_Score=143, Evalue=7e-35,
Organism=Saccharomyces cerevisiae, GI6320016, Length=223, Percent_Identity=33.6322869955157, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24638766, Length=353, Percent_Identity=30.8781869688385, Blast_Score=152, Evalue=3e-37,
Organism=Drosophila melanogaster, GI28574560, Length=353, Percent_Identity=30.3116147308782, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24658560, Length=366, Percent_Identity=29.2349726775956, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281361666, Length=416, Percent_Identity=27.6442307692308, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24646341, Length=416, Percent_Identity=27.6442307692308, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17136796, Length=416, Percent_Identity=27.6442307692308, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24583992, Length=316, Percent_Identity=30.0632911392405, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24583988, Length=282, Percent_Identity=30.4964539007092, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24583986, Length=282, Percent_Identity=30.4964539007092, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24583984, Length=282, Percent_Identity=30.4964539007092, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI20129479, Length=233, Percent_Identity=32.1888412017167, Blast_Score=118, Evalue=6e-27,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR004100
- InterPro:   IPR005714
- InterPro:   IPR013380 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 48381; Mature: 48250

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQIVMTLSLDHIPDQLRHAIDECRLIQIRGRVTQVTGTLLKAVVPGVRIGELCHLRNPD
CCEEEEEEEHHHCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
NTLSLQAEVIGFAQHQALLTPLGEMFGISSNTEVSPTGAMHQVGVGEHLLGQVLDGLGNP
CCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCC
FGGGHLPEPEAWYPVYRDAPAPMSRKRIAEPISLGIRAIDGLLTCGEGQRMGIFAAAGGG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
KSTLLASLIRSAEVDVTVLALIGERGREVREFIEADLGEEGLKKAVLVVATSDRPAMERA
HHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHCEEEEEECCCCHHHHHH
KAGFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPR
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LMERAGQSDKGSITALYTVLVEGDDMTEPVADETRSILDGHIILSRKLAAANHYPAIDVL
HHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHH
RSASRVMNQIIEPEHQAQAGRLRSWLAKYEEVELLLQIGEYQKGQDKVADEAIARIETIR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QWLRQGTHEPSSLPEALSTLEALTR
HHHHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQIVMTLSLDHIPDQLRHAIDECRLIQIRGRVTQVTGTLLKAVVPGVRIGELCHLRNPD
CEEEEEEEHHHCHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCCCCHHHHHCCCCCC
NTLSLQAEVIGFAQHQALLTPLGEMFGISSNTEVSPTGAMHQVGVGEHLLGQVLDGLGNP
CCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHCCC
FGGGHLPEPEAWYPVYRDAPAPMSRKRIAEPISLGIRAIDGLLTCGEGQRMGIFAAAGGG
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
KSTLLASLIRSAEVDVTVLALIGERGREVREFIEADLGEEGLKKAVLVVATSDRPAMERA
HHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHCCCHHHHHCEEEEEECCCCHHHHHH
KAGFVATSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPR
HHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
LMERAGQSDKGSITALYTVLVEGDDMTEPVADETRSILDGHIILSRKLAAANHYPAIDVL
HHHHCCCCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHH
RSASRVMNQIIEPEHQAQAGRLRSWLAKYEEVELLLQIGEYQKGQDKVADEAIARIETIR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
QWLRQGTHEPSSLPEALSTLEALTR
HHHHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8132449; 2160939 [H]