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The map label for this gene is ascV [H]

Identifier: 145301453

GI number: 145301453

Start: 68769

End: 70934

Strand: Reverse

Name: ascV [H]

Synonym: ASA_P5G070

Alternate gene names: 145301453

Gene position: 70934-68769 (Counterclockwise)

Preceding gene: 145301454

Following gene: 145301452

Centisome position: 45.73

GC content: 60.99

Gene sequence:

>2166_bases
ATGAAGCCCGTTTTGCCTATCAACAATACCTCGAACTGGAAGAGCAGAATGAATCAACGCACCCTTGAGTTGCTGCGCCG
GATAGGCGAACGCAAGGACATCATGCTGGCGATCCTGCTGCTGGCCATCGTCTTTATGATGGTCTTGCCGCTGCCGCCGG
TGGCCCTCGATATCCTGATTGCCATCAACATGACCATCTCGGTGGTACTGCTGATGATGGCGGTTTATATCAATTCGCCG
CTGCAGTTCTCCGCCTTTCCGGCGGTGCTGCTGATCACCACCCTGTTCCGGCTTGCCTTGTCGGTGAGTACCACCCGGAT
GATCCTGCTGCAGGCTGATGCGGGGCAGATAGTCTACACCTTCGGCAACTTCGTGGTGGGGGGCAATCTGGTGGTGGGGA
TCGTCATCTTCCTCATCATCACCATCGTCCAGTTTCTGGTGATCACCAAGGGCTCGGAGCGGGTCGCCGAGGTGAGCGCC
CGCTTTTCCCTCGATGCCATGCCGGGTAAGCAGATGAGTATCGATGGTGACATGCGCGCCGGGGTGATCGACGTGCACGA
GGCGCGGGATCGCCGCGGGGTCATCGAGAAGGAGAGCCAGATGTTCGGCTCCATGGATGGCGCCATGAAGTTTGTGAAGG
GGGACGCCATCGCGGGCCTCATCATCATCTTCGTCAACATCCTCGGTGGCGTCACCATCGGGGTGACCCAGAAGGGGTTA
TCCGCCGCCGATGCGCTGCAGCTCTACTCCATCCTGACGGTGGGTGATGGCATGGTCTCCCAGGTGCCGGCGCTGCTGAT
CGCCATCACCGCGGGCATTATCGTCACCCGGGTCTCCTCCGAAGAGTCTTCCGATCTGGGTACCGATATCGGCGCCCAGG
TGGTGGCCCAGCCCAAGGCGCTACTGATCGGCGGTCTGCTGCTGGTGCTGTTCGGGTTGATCCCGGGCTTCCCGATGATC
ACCTTCTTTGCGCTGTCGGCCATCGTCACGGCGGGCGGTTACTTTATCGGCTTGCGACAACGCAAGGCGCAAAGCAGCAA
CAGTCAGGATCTTCCTGCCGTGCTGGCGCAGGGGGCCGGGGCCCCAGCTGCCCGCAGCAAGCCAAAACCGGGCAGCAAGC
CGCGGGGCAAGCTGGGGGAGAAGGAGGAGTTTGCCATGACGGTGCCGCTCCTTATCGATGTGGATGCTGCTTTGCAGGCC
GAGCTGGAGGCGATTGCCCTCAACGACGAACTGGTGCGGGTGCGCCGCGCCCTCTATCTCGATCTCGGGGTGCCTTTCCC
GGGTATTCACCTGCGTTTCAACGAGGGGATGGGGCCTGGCGAATACCTGATCCAGCTGCAGGAGGTGCCGGTCGCCCGCG
GTCTGCTGCGCCCGGGCCATCAGCTGGTGCAGGAGAGCGCCTCCCAGCTCGATCTGCTGGGGATCCCCTACGAAGAGGGG
GCGCCGTTACTGCCGGGACAACCGACCTTGTGGGTCGCTAATGAACATCAGGAGCGACTGGAGAAGTCACGGCTGGCCAC
CCTCACCACCGATCAGGTGATGACCTGGCATCTATCCCATGTGCTGCGGGAATATGCCGAGGACTTTATCGGCATTCAGG
AGACCCGCTACCTGCTGGAGCAGATGGAGGGGAGCTATAGCGAGCTGGTGAAGGAGGCGCAACGCATCATCCCGCTGCAG
CGTATGACCGAAATTTTGCAGCGGCTGGTGGGGGAGGATATCTCCATCCGCAACATGCGCGCCATCCTCGAGGCGATGGT
GGAGTGGGGCCAGAAGGAGAAGGATGTGGTGCAGCTCACCGAGTACATCCGTAGCAGCCTCAAGCGCTACATCTGCTACA
AGTACGCCAACGGCAACAACATTTTGCCTGCCTATCTGCTCGATCAGCAGGTGGAGGAGCAGCTCCGCGGCGGCATTCGC
CAGACTAGTGCCGGCAGCTATCTGGCGCTCGATCCCACTATTACCCAGAGCTTCCTCGATCAGGTGCGCCACACCGTCGG
TGATCTGGCCCAGATGCAGAACAAACCGGTGCTCATTGTCTCCATGGATATCCGCCGCTATGTGCGCAAGCTCATCGAGG
GGGATTACCATGCCCTGCCGGTGCTCTCCTATCAGGAGCTGACCCAGCAGATCAATATCCAGCCCCTCGGGAGGGTCTGC
CTGTGA

Upstream 100 bases:

>100_bases
GCGGCGCTGGCCCATGTCGATCAGCTGATGCAGCAAGGGGAGGCCGACGGCCCGCTCTGGCTCTGTCGCAGCCGAGCCTG
CCAGTTGGCAGGGCGGCTGG

Downstream 100 bases:

>100_bases
GGGGGGACCCGTTAACCTCTGACCCCCTGATCCCCTGGCTGCAGGCCAAGGGTGTGGCGGTTGCCTCTCACTATCTGGGG
GCAACCCCCATCCAGCTCGG

Product: AscV protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 721; Mature: 721

Protein sequence:

>721_residues
MKPVLPINNTSNWKSRMNQRTLELLRRIGERKDIMLAILLLAIVFMMVLPLPPVALDILIAINMTISVVLLMMAVYINSP
LQFSAFPAVLLITTLFRLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLVVGIVIFLIITIVQFLVITKGSERVAEVSA
RFSLDAMPGKQMSIDGDMRAGVIDVHEARDRRGVIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGL
SAADALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEESSDLGTDIGAQVVAQPKALLIGGLLLVLFGLIPGFPMI
TFFALSAIVTAGGYFIGLRQRKAQSSNSQDLPAVLAQGAGAPAARSKPKPGSKPRGKLGEKEEFAMTVPLLIDVDAALQA
ELEAIALNDELVRVRRALYLDLGVPFPGIHLRFNEGMGPGEYLIQLQEVPVARGLLRPGHQLVQESASQLDLLGIPYEEG
APLLPGQPTLWVANEHQERLEKSRLATLTTDQVMTWHLSHVLREYAEDFIGIQETRYLLEQMEGSYSELVKEAQRIIPLQ
RMTEILQRLVGEDISIRNMRAILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLLDQQVEEQLRGGIR
QTSAGSYLALDPTITQSFLDQVRHTVGDLAQMQNKPVLIVSMDIRRYVRKLIEGDYHALPVLSYQELTQQINIQPLGRVC
L

Sequences:

>Translated_721_residues
MKPVLPINNTSNWKSRMNQRTLELLRRIGERKDIMLAILLLAIVFMMVLPLPPVALDILIAINMTISVVLLMMAVYINSP
LQFSAFPAVLLITTLFRLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLVVGIVIFLIITIVQFLVITKGSERVAEVSA
RFSLDAMPGKQMSIDGDMRAGVIDVHEARDRRGVIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGL
SAADALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEESSDLGTDIGAQVVAQPKALLIGGLLLVLFGLIPGFPMI
TFFALSAIVTAGGYFIGLRQRKAQSSNSQDLPAVLAQGAGAPAARSKPKPGSKPRGKLGEKEEFAMTVPLLIDVDAALQA
ELEAIALNDELVRVRRALYLDLGVPFPGIHLRFNEGMGPGEYLIQLQEVPVARGLLRPGHQLVQESASQLDLLGIPYEEG
APLLPGQPTLWVANEHQERLEKSRLATLTTDQVMTWHLSHVLREYAEDFIGIQETRYLLEQMEGSYSELVKEAQRIIPLQ
RMTEILQRLVGEDISIRNMRAILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLLDQQVEEQLRGGIR
QTSAGSYLALDPTITQSFLDQVRHTVGDLAQMQNKPVLIVSMDIRRYVRKLIEGDYHALPVLSYQELTQQINIQPLGRVC
L
>Mature_721_residues
MKPVLPINNTSNWKSRMNQRTLELLRRIGERKDIMLAILLLAIVFMMVLPLPPVALDILIAINMTISVVLLMMAVYINSP
LQFSAFPAVLLITTLFRLALSVSTTRMILLQADAGQIVYTFGNFVVGGNLVVGIVIFLIITIVQFLVITKGSERVAEVSA
RFSLDAMPGKQMSIDGDMRAGVIDVHEARDRRGVIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGL
SAADALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEESSDLGTDIGAQVVAQPKALLIGGLLLVLFGLIPGFPMI
TFFALSAIVTAGGYFIGLRQRKAQSSNSQDLPAVLAQGAGAPAARSKPKPGSKPRGKLGEKEEFAMTVPLLIDVDAALQA
ELEAIALNDELVRVRRALYLDLGVPFPGIHLRFNEGMGPGEYLIQLQEVPVARGLLRPGHQLVQESASQLDLLGIPYEEG
APLLPGQPTLWVANEHQERLEKSRLATLTTDQVMTWHLSHVLREYAEDFIGIQETRYLLEQMEGSYSELVKEAQRIIPLQ
RMTEILQRLVGEDISIRNMRAILEAMVEWGQKEKDVVQLTEYIRSSLKRYICYKYANGNNILPAYLLDQQVEEQLRGGIR
QTSAGSYLALDPTITQSFLDQVRHTVGDLAQMQNKPVLIVSMDIRRYVRKLIEGDYHALPVLSYQELTQQINIQPLGRVC
L

Specific function: Could be involved in the secretion of the yop virulence proteins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=683, Percent_Identity=34.2606149341142, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 79314; Mature: 79314

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPVLPINNTSNWKSRMNQRTLELLRRIGERKDIMLAILLLAIVFMMVLPLPPVALDILI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AINMTISVVLLMMAVYINSPLQFSAFPAVLLITTLFRLALSVSTTRMILLQADAGQIVYT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEE
FGNFVVGGNLVVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDGDMRA
ECCEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCC
GVIDVHEARDRRGVIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGL
CEEEHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCC
SAADALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEESSDLGTDIGAQVVAQPKA
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCHH
LLIGGLLLVLFGLIPGFPMITFFALSAIVTAGGYFIGLRQRKAQSSNSQDLPAVLAQGAG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCCCHHHHHHCCCC
APAARSKPKPGSKPRGKLGEKEEFAMTVPLLIDVDAALQAELEAIALNDELVRVRRALYL
CCCCCCCCCCCCCCCCCCCCCCHHEEEECCEEECCHHHHHHHHHHCCCHHHHHHHHHHHH
DLGVPFPGIHLRFNEGMGPGEYLIQLQEVPVARGLLRPGHQLVQESASQLDLLGIPYEEG
CCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHCEEECCCCCCC
APLLPGQPTLWVANEHQERLEKSRLATLTTDQVMTWHLSHVLREYAEDFIGIQETRYLLE
CCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QMEGSYSELVKEAQRIIPLQRMTEILQRLVGEDISIRNMRAILEAMVEWGQKEKDVVQLT
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
EYIRSSLKRYICYKYANGNNILPAYLLDQQVEEQLRGGIRQTSAGSYLALDPTITQSFLD
HHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHH
QVRHTVGDLAQMQNKPVLIVSMDIRRYVRKLIEGDYHALPVLSYQELTQQINIQPLGRVC
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCEECCCCHHHHHHHCCCCCCCCCC
L
C
>Mature Secondary Structure
MKPVLPINNTSNWKSRMNQRTLELLRRIGERKDIMLAILLLAIVFMMVLPLPPVALDILI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AINMTISVVLLMMAVYINSPLQFSAFPAVLLITTLFRLALSVSTTRMILLQADAGQIVYT
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEEEE
FGNFVVGGNLVVGIVIFLIITIVQFLVITKGSERVAEVSARFSLDAMPGKQMSIDGDMRA
ECCEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEECCCCCCCCCCCCCCC
GVIDVHEARDRRGVIEKESQMFGSMDGAMKFVKGDAIAGLIIIFVNILGGVTIGVTQKGL
CEEEHHHHHHHCCCHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCC
SAADALQLYSILTVGDGMVSQVPALLIAITAGIIVTRVSSEESSDLGTDIGAQVVAQPKA
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCHHHHHHHCCHH
LLIGGLLLVLFGLIPGFPMITFFALSAIVTAGGYFIGLRQRKAQSSNSQDLPAVLAQGAG
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCCCCCHHHHHHCCCC
APAARSKPKPGSKPRGKLGEKEEFAMTVPLLIDVDAALQAELEAIALNDELVRVRRALYL
CCCCCCCCCCCCCCCCCCCCCCHHEEEECCEEECCHHHHHHHHHHCCCHHHHHHHHHHHH
DLGVPFPGIHLRFNEGMGPGEYLIQLQEVPVARGLLRPGHQLVQESASQLDLLGIPYEEG
CCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHCEEECCCCCCC
APLLPGQPTLWVANEHQERLEKSRLATLTTDQVMTWHLSHVLREYAEDFIGIQETRYLLE
CCCCCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
QMEGSYSELVKEAQRIIPLQRMTEILQRLVGEDISIRNMRAILEAMVEWGQKEKDVVQLT
HHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
EYIRSSLKRYICYKYANGNNILPAYLLDQQVEEQLRGGIRQTSAGSYLALDPTITQSFLD
HHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEECHHHHHHHHH
QVRHTVGDLAQMQNKPVLIVSMDIRRYVRKLIEGDYHALPVLSYQELTQQINIQPLGRVC
HHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCEECCCCHHHHHHHCCCCCCCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11402007 [H]