Click here to switch to the map view.

The map label for this gene is acrH [H]

Identifier: 145301449

GI number: 145301449

Start: 66385

End: 66888

Strand: Reverse

Name: acrH [H]

Synonym: ASA_P5G066

Alternate gene names: 145301449

Gene position: 66888-66385 (Counterclockwise)

Preceding gene: 145301450

Following gene: 145301448

Centisome position: 43.13

GC content: 57.14

Gene sequence:

>504_bases
ATGCAGACCGACACCACCCTGACCCCGGAATATGAAGCAGAGCTGGAGGCCTTTATGGCTGACGGTGGTACCCTGGCTAT
GCTGCAGGATATCTCTGGCGACACCTTGGAACAGCTCTATGCCCTGGCCTTTAGCCAGTATCAGGCCGGCAAGTGGGAAG
ATGCTCACAAAATCTTCCAGGCTCTCTGCATGCTGGATCACTACGAGCCACGCTATTTCCTCGGGCTGGGTGCTTGCCGT
CAGGCGATGGGGGAGTTTGAAACGGCAGTTCAGAGTTACAGCTTTGGCGCCATGCTCGACCTGAAAGATCCCCGTTTCCC
ATTTCATGCAGGCGAGTGCCGGCTGCAACAAGGTGATTTGAACGGTGCCGAGAGTGGCTTCCACTCGGCCCGACTGCTGG
CGGACACAGATCCCCAGCAGGCAGACCTGGCGGCAAGCGCCAAGGTCATGTTGGAAGCCATCGCAATCAGAAGGGATCTG
CAAGATGAACCCGATCAGCAATGA

Upstream 100 bases:

>100_bases
CAGTTCGCGCTACAACGCTGCCATCGAGGCACTCAACCGCTTTATCCAGAAATACGACAGCATCATGCGCGACATTCTTG
GCGCAATTTGAGGAGAGATC

Downstream 100 bases:

>100_bases
AAGACAGGTTTCCCCGCTGGGAAACACAGGTGACGTCGCGGGCCTCGTACCCGTTACCCAGCCTCGCAGTGAAACACGGC
TCGATGCCGCAACGGTGCAA

Product: AcrH protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 167; Mature: 167

Protein sequence:

>167_residues
MQTDTTLTPEYEAELEAFMADGGTLAMLQDISGDTLEQLYALAFSQYQAGKWEDAHKIFQALCMLDHYEPRYFLGLGACR
QAMGEFETAVQSYSFGAMLDLKDPRFPFHAGECRLQQGDLNGAESGFHSARLLADTDPQQADLAASAKVMLEAIAIRRDL
QDEPDQQ

Sequences:

>Translated_167_residues
MQTDTTLTPEYEAELEAFMADGGTLAMLQDISGDTLEQLYALAFSQYQAGKWEDAHKIFQALCMLDHYEPRYFLGLGACR
QAMGEFETAVQSYSFGAMLDLKDPRFPFHAGECRLQQGDLNGAESGFHSARLLADTDPQQADLAASAKVMLEAIAIRRDL
QDEPDQQ
>Mature_167_residues
MQTDTTLTPEYEAELEAFMADGGTLAMLQDISGDTLEQLYALAFSQYQAGKWEDAHKIFQALCMLDHYEPRYFLGLGACR
QAMGEFETAVQSYSFGAMLDLKDPRFPFHAGECRLQQGDLNGAESGFHSARLLADTDPQQADLAASAKVMLEAIAIRRDL
QDEPDQQ

Specific function: Mediates the negative regulation of the lcrGVH operon by ATP or calcium. Acts as a modulator of the yop operon expression [H]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lcrH/sycD chaperone family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005415
- InterPro:   IPR016379
- InterPro:   IPR011716
- InterPro:   IPR013026
- InterPro:   IPR011990 [H]

Pfam domain/function: PF07720 TPR_3 [H]

EC number: NA

Molecular weight: Translated: 18566; Mature: 18566

Theoretical pI: Translated: 4.07; Mature: 4.07

Prosite motif: PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTDTTLTPEYEAELEAFMADGGTLAMLQDISGDTLEQLYALAFSQYQAGKWEDAHKIFQ
CCCCCCCCCCHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALCMLDHYEPRYFLGLGACRQAMGEFETAVQSYSFGAMLDLKDPRFPFHAGECRLQQGDL
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCC
NGAESGFHSARLLADTDPQQADLAASAKVMLEAIAIRRDLQDEPDQQ
CCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQTDTTLTPEYEAELEAFMADGGTLAMLQDISGDTLEQLYALAFSQYQAGKWEDAHKIFQ
CCCCCCCCCCHHHHHHHHHCCCCCEEEEHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALCMLDHYEPRYFLGLGACRQAMGEFETAVQSYSFGAMLDLKDPRFPFHAGECRLQQGDL
HHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCEEEECCCC
NGAESGFHSARLLADTDPQQADLAASAKVMLEAIAIRRDLQDEPDQQ
CCCCCCCHHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477361; 9746557; 9748454; 11586360 [H]