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The map label for this gene is ascC [H]

Identifier: 145301440

GI number: 145301440

Start: 58726

End: 60579

Strand: Reverse

Name: ascC [H]

Synonym: ASA_P5G057

Alternate gene names: 145301440

Gene position: 60579-58726 (Counterclockwise)

Preceding gene: 145301441

Following gene: 145301439

Centisome position: 39.06

GC content: 60.84

Gene sequence:

>1854_bases
ATGGAGACAGATGATATGGCACCCTTGAGCGTGCAACCCCTGCTGCGTCCCCTGTTGTGGATCTGCCTCGCCGTGATGGC
GTGGCAGCGTCCCGCCATGGCACAGGAGCTGGACTGGGTGCCCATGCCTTACAGTTATGTGGCAGAAGGGGAGAGTCTGC
GCGACGTGCTGGTCAACTTCGGTGCCAACTACGAGGTTTCCGTGGTAGTCAGCGACAAGGTCAACGATCAGGTCAACGGC
CAGTTTGAGCATGACGAGCCGCTCGCCTTTTTGCAGCAGCTCTCCTCCCTCTACAACCTGGTCTGGTACTACGACGGCAA
TGTGCTCTACGTCTTCAAGAACAGCGAAGTGCAGTCCCGTCTCATCAATCTGGAGCAGACTGGCGCAGCAGAACTCAAAC
AGGCGCTTCAACGAGCCGGGATCTGGGAGCCCCGTTTTGGCTGGCGCCCCGATGCGGATAACAGGCTGCTCTATGTCTCC
GGACCGCCCCGTTACCTTGAATTGATCGAACAGACCGCGCTGGCATTGGAGCAACAGTCCCAGCTACGCAGCGAGAAGAC
CGGGCCGCTGGCCATCGAGATCTTTCCCCTCAAGTACGCCTCGGCTACCGATCGCTCCATCCAGTACCGCGATACCGATG
TGGCGGCGCCCGGTGTGGCGACCATTTTGGCCAAGCTGCTGAGCGATGCTGGCGTGCAGATGGTCAACGGCGAGGGTAAC
AAGGCAGCGACAGCCACCTCCGGTCAGGCCATCGTGCAGGCCGATCCTTCCCTCAATGCGGTGATCGTGCGCGATGCTCC
GGAGCGGATGGCGATGTACGGCAAGTTGATCGCCGCGCTCGACAAACCGGCGGCCCGCATTGAGGTGGCGCTCTCCATCA
TCGATATCAATGCCGAGGATCTCTCCCAGCTGGGGGTGGATTGGCGAGTGGGGATCCGCACCGGTTCTAACCAGCAGGTG
ATTATCAAGACCACCGGCGATCGCAAGGGGATTGAAGGGGGCGCCGCGCTCGGCAGTCTGGTGGATTCCAAAGGGCTCGA
CTATCTGCTGGCCCGAGTCAATCTGCTGGAAAACGAAGGCAATGCCCAGGTGGTCTCCCGCCCGACCTTGCTGACCCAGG
AGAACACCCAGGCGGTGATCGACCACAGCGAGACTTATTACGTGAAGATCAGCGGTGAGCGGGTGGCCGAGCTGCAGGGG
ATCACCTACGGCACCATGTTGCGGATGACCCCCCGGGTGATCCAGATGGGTGACAGACCCGAGATCAGCCTGAGCCTCCA
TATCGAGGATGGCAACCAGAAACCCAACAGTGCGGGGGCCGATGGCATTCCTACCATCAGTCGTACCGTGGTCGATACCA
TCGCCCGGGTCGGCCACGGCCAGAGCCTGCTGATAGGCGGTATCTACCGCGACGAGATGAGCGAGAACCTGAGCAAGGTG
CCCTTCCTTGGTGACATCCCTTATCTGGGGGCGCTGTTCCGTAGTAAGGACACCCAGACCCGTCGCTCAGTGCGGCTATT
TATCATCGAGCCTCGTCTGATTGATGACGGTATTGCCCACTATCTGGCCCTCGGCAATGGTCAGGATCTGCGCGCCGGGG
TGCTCGGGGCTGATGAAATCTCCAATCAGAGTCTCTCCCTTGGCAAGGTGCTGGGGGGCGCGCAATGCCAGCCGCTGGCT
GCAGCCCGTGACGTGCAGCAGCTGCTGCGTCAGGGGGGTAAGAGCTCGTCCCTCACTCAGTGCCGGATGGGCAATGAGCT
GGGGTGGCGTCTGGTCGAAATGAACAAGGATCAAAAATGTACACCGGCCGCCAGCTGGTGTGTGCAGGCGGGCAATGAGG
GCGCTACCCGATGA

Upstream 100 bases:

>100_bases
AGTGGCTCGACGAGGCGCTGCTGGCGGAGCGCCTGAGCCAGCACATCGCCCTGCTGGAGCGCTTGGAACCCCAATTGACC
GAGGCCGCCTTGGCCCCCCA

Downstream 100 bases:

>100_bases
GCTGGAAGTGCCGCGTATATCGCGGGCTCAACCGCGGGGTAGAAGTTCCTCTGCCGGAGGGGCGTCTGGTCATCGGTTCC
GATCCCCTCAAGGCTGATCT

Product: AscC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 617; Mature: 617

Protein sequence:

>617_residues
METDDMAPLSVQPLLRPLLWICLAVMAWQRPAMAQELDWVPMPYSYVAEGESLRDVLVNFGANYEVSVVVSDKVNDQVNG
QFEHDEPLAFLQQLSSLYNLVWYYDGNVLYVFKNSEVQSRLINLEQTGAAELKQALQRAGIWEPRFGWRPDADNRLLYVS
GPPRYLELIEQTALALEQQSQLRSEKTGPLAIEIFPLKYASATDRSIQYRDTDVAAPGVATILAKLLSDAGVQMVNGEGN
KAATATSGQAIVQADPSLNAVIVRDAPERMAMYGKLIAALDKPAARIEVALSIIDINAEDLSQLGVDWRVGIRTGSNQQV
IIKTTGDRKGIEGGAALGSLVDSKGLDYLLARVNLLENEGNAQVVSRPTLLTQENTQAVIDHSETYYVKISGERVAELQG
ITYGTMLRMTPRVIQMGDRPEISLSLHIEDGNQKPNSAGADGIPTISRTVVDTIARVGHGQSLLIGGIYRDEMSENLSKV
PFLGDIPYLGALFRSKDTQTRRSVRLFIIEPRLIDDGIAHYLALGNGQDLRAGVLGADEISNQSLSLGKVLGGAQCQPLA
AARDVQQLLRQGGKSSSLTQCRMGNELGWRLVEMNKDQKCTPAASWCVQAGNEGATR

Sequences:

>Translated_617_residues
METDDMAPLSVQPLLRPLLWICLAVMAWQRPAMAQELDWVPMPYSYVAEGESLRDVLVNFGANYEVSVVVSDKVNDQVNG
QFEHDEPLAFLQQLSSLYNLVWYYDGNVLYVFKNSEVQSRLINLEQTGAAELKQALQRAGIWEPRFGWRPDADNRLLYVS
GPPRYLELIEQTALALEQQSQLRSEKTGPLAIEIFPLKYASATDRSIQYRDTDVAAPGVATILAKLLSDAGVQMVNGEGN
KAATATSGQAIVQADPSLNAVIVRDAPERMAMYGKLIAALDKPAARIEVALSIIDINAEDLSQLGVDWRVGIRTGSNQQV
IIKTTGDRKGIEGGAALGSLVDSKGLDYLLARVNLLENEGNAQVVSRPTLLTQENTQAVIDHSETYYVKISGERVAELQG
ITYGTMLRMTPRVIQMGDRPEISLSLHIEDGNQKPNSAGADGIPTISRTVVDTIARVGHGQSLLIGGIYRDEMSENLSKV
PFLGDIPYLGALFRSKDTQTRRSVRLFIIEPRLIDDGIAHYLALGNGQDLRAGVLGADEISNQSLSLGKVLGGAQCQPLA
AARDVQQLLRQGGKSSSLTQCRMGNELGWRLVEMNKDQKCTPAASWCVQAGNEGATR
>Mature_617_residues
METDDMAPLSVQPLLRPLLWICLAVMAWQRPAMAQELDWVPMPYSYVAEGESLRDVLVNFGANYEVSVVVSDKVNDQVNG
QFEHDEPLAFLQQLSSLYNLVWYYDGNVLYVFKNSEVQSRLINLEQTGAAELKQALQRAGIWEPRFGWRPDADNRLLYVS
GPPRYLELIEQTALALEQQSQLRSEKTGPLAIEIFPLKYASATDRSIQYRDTDVAAPGVATILAKLLSDAGVQMVNGEGN
KAATATSGQAIVQADPSLNAVIVRDAPERMAMYGKLIAALDKPAARIEVALSIIDINAEDLSQLGVDWRVGIRTGSNQQV
IIKTTGDRKGIEGGAALGSLVDSKGLDYLLARVNLLENEGNAQVVSRPTLLTQENTQAVIDHSETYYVKISGERVAELQG
ITYGTMLRMTPRVIQMGDRPEISLSLHIEDGNQKPNSAGADGIPTISRTVVDTIARVGHGQSLLIGGIYRDEMSENLSKV
PFLGDIPYLGALFRSKDTQTRRSVRLFIIEPRLIDDGIAHYLALGNGQDLRAGVLGADEISNQSLSLGKVLGGAQCQPLA
AARDVQQLLRQGGKSSSLTQCRMGNELGWRLVEMNKDQKCTPAASWCVQAGNEGATR

Specific function: Very likely required for the export process of the yop proteins [H]

COG id: COG1450

COG function: function code NU; Type II secretory pathway, component PulD

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=355, Percent_Identity=25.6338028169014, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082242, Length=399, Percent_Identity=24.3107769423559, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005644
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR003522 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N [H]

EC number: NA

Molecular weight: Translated: 67406; Mature: 67406

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METDDMAPLSVQPLLRPLLWICLAVMAWQRPAMAQELDWVPMPYSYVAEGESLRDVLVNF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHCCHHHHHHHHHC
GANYEVSVVVSDKVNDQVNGQFEHDEPLAFLQQLSSLYNLVWYYDGNVLYVFKNSEVQSR
CCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCEEEEEECCHHHHH
LINLEQTGAAELKQALQRAGIWEPRFGWRPDADNRLLYVSGPPRYLELIEQTALALEQQS
HHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
QLRSEKTGPLAIEIFPLKYASATDRSIQYRDTDVAAPGVATILAKLLSDAGVQMVNGEGN
HHHHCCCCCEEEEEEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCC
KAATATSGQAIVQADPSLNAVIVRDAPERMAMYGKLIAALDKPAARIEVALSIIDINAED
CCEEECCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHH
LSQLGVDWRVGIRTGSNQQVIIKTTGDRKGIEGGAALGSLVDSKGLDYLLARVNLLENEG
HHHCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCC
NAQVVSRPTLLTQENTQAVIDHSETYYVKISGERVAELQGITYGTMLRMTPRVIQMGDRP
CCEEEECCEEEECCCCEEEEECCCEEEEEECCCCEEHHCCCEEHHHHHCCHHHHCCCCCC
EISLSLHIEDGNQKPNSAGADGIPTISRTVVDTIARVGHGQSLLIGGIYRDEMSENLSKV
CEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHC
PFLGDIPYLGALFRSKDTQTRRSVRLFIIEPRLIDDGIAHYLALGNGQDLRAGVLGADEI
CCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHEEECCCCCCEECCCCHHHH
SNQSLSLGKVLGGAQCQPLAAARDVQQLLRQGGKSSSLTQCRMGNELGWRLVEMNKDQKC
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEECCCCCCC
TPAASWCVQAGNEGATR
CHHHHHHHHCCCCCCCC
>Mature Secondary Structure
METDDMAPLSVQPLLRPLLWICLAVMAWQRPAMAQELDWVPMPYSYVAEGESLRDVLVNF
CCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHCCHHHHHHHHHC
GANYEVSVVVSDKVNDQVNGQFEHDEPLAFLQQLSSLYNLVWYYDGNVLYVFKNSEVQSR
CCCEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHEEEEEECCCEEEEEECCHHHHH
LINLEQTGAAELKQALQRAGIWEPRFGWRPDADNRLLYVSGPPRYLELIEQTALALEQQS
HHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
QLRSEKTGPLAIEIFPLKYASATDRSIQYRDTDVAAPGVATILAKLLSDAGVQMVNGEGN
HHHHCCCCCEEEEEEEEEECCCCCCCEEECCCCCCCCCHHHHHHHHHHCCCEEEECCCCC
KAATATSGQAIVQADPSLNAVIVRDAPERMAMYGKLIAALDKPAARIEVALSIIDINAED
CCEEECCCCEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCHHH
LSQLGVDWRVGIRTGSNQQVIIKTTGDRKGIEGGAALGSLVDSKGLDYLLARVNLLENEG
HHHCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCC
NAQVVSRPTLLTQENTQAVIDHSETYYVKISGERVAELQGITYGTMLRMTPRVIQMGDRP
CCEEEECCEEEECCCCEEEEECCCEEEEEECCCCEEHHCCCEEHHHHHCCHHHHCCCCCC
EISLSLHIEDGNQKPNSAGADGIPTISRTVVDTIARVGHGQSLLIGGIYRDEMSENLSKV
CEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHC
PFLGDIPYLGALFRSKDTQTRRSVRLFIIEPRLIDDGIAHYLALGNGQDLRAGVLGADEI
CCCCCCHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHEEECCCCCCEECCCCHHHH
SNQSLSLGKVLGGAQCQPLAAARDVQQLLRQGGKSSSLTQCRMGNELGWRLVEMNKDQKC
CCCCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEECCCCCCC
TPAASWCVQAGNEGATR
CHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1860816 [H]