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The map label for this gene is hfq [H]

Identifier: 17935350

GI number: 17935350

Start: 1446124

End: 1446366

Strand: Direct

Name: hfq [H]

Synonym: Atu1450

Alternate gene names: 17935350

Gene position: 1446124-1446366 (Clockwise)

Preceding gene: 15888774

Following gene: 159184763

Centisome position: 50.89

GC content: 53.5

Gene sequence:

>243_bases
ATGGCGGAACGTTCTCAAAACCTTCAGGATCTCTTCCTCAATACCGTTCGTAAGCAGAAGATTTCGCTCACGATTTTCCT
GATCAACGGCGTCAAGCTGACGGGCGTTGTTACCTCCTTCGACAATTTCTGCGTGCTTCTGCGTCGCGATGGTCACTCGC
AGCTGGTCTACAAGCATGCAATCTCCACCATCATGCCCGGCCAGCCGATGCAGATGTTCGAGAGCGAAGAAGGCGCTGCC
TGA

Upstream 100 bases:

>100_bases
GAGTTTGAGGTCGGCCAAGCGGGGGACAAGACTCGGCCGGCTTATTATTGATTGATTATTTTCCGGTATCCCTGCCGGCA
ATAAAGAAAGAAGCGGCGCC

Downstream 100 bases:

>100_bases
TCAGGCTCCTTTAACGGTATCTTCGACAGAGACTGACCTGAATCGGAACATTTCCGGTTCCGTCAGGTTAATCTCCATGG
CCGCCCGCGCGGATGCGGTC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 80; Mature: 79

Protein sequence:

>80_residues
MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPMQMFESEEGAA

Sequences:

>Translated_80_residues
MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPMQMFESEEGAA
>Mature_79_residues
AERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHAISTIMPGQPMQMFESEEGAA

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=77, Percent_Identity=44.1558441558442, Blast_Score=81, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9015; Mature: 8883

Theoretical pI: Translated: 8.53; Mature: 8.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCCHHHHHHHHHHCCEEEEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPGQPMQMFESEEGAA
HHHCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
AERSQNLQDLFLNTVRKQKISLTIFLINGVKLTGVVTSFDNFCVLLRRDGHSQLVYKHA
CCCCCCHHHHHHHHHHCCEEEEEEEEECCEEEEEEEECCCCEEEEEEECCCCHHHHHHH
ISTIMPGQPMQMFESEEGAA
HHHCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA